AUTONOMIC PHARMACOLOGY

Cholinergic Anticholinergic
1. Directly acting 1. Anti-muscarinic
A. Choline ester: A. Naturally occurring alkaloids:
i) Acetylcholine i) Atropine
ii) Betha-choline ii) Scopolamine
iii) Metha-choline B. Atropine substitutes:
iv) Carbachol a) Atropine like mydriatics:
B. Alkaloids i) Homatropine
i) Pilocarpine ii) Cyclopentolate
ii) Muscarine iii) Tropicamide
iii) Nicotine b) Smooth muscle relaxant:
2. Indirectly acting i) Methantheline
A. Reversible ii) Propantheline
i) Physo-stigmine iii) Oxyphenonium
ii) Neo-stigmine iv) Hyosine-N-butyl bromide
iii) Pyrido-stigmine v) Dicyclomine
B. Irreversible vi) Tiemonium methyl sulphate
i) Malathion c) Anti-parkinsonism:
ii) Parathion i) Benztropine
iii) Eco-thiophate ii) Benzhexol
iv) Tetra-Ethyl iii) Biperimide
Pyrophosphate d) Anti-asthmatics:
v) Octa-Methyl i) Ipratropium
Pyrophosphate ii) Oxytropium
2. Antinicotinic
A. Neuromuscular blocking drugs:
a) Non-depolarizing/reversible/competitive
i) Gallamine
ii) Isoquinidine derivatives:
 D-tubocurarine
 Atracurium
 Pancurium
 Doxacurium
 Mivocurium
iii) Steroids derivatives:
 Pancuronium
 Vecuronium
 Rocuronium
b) Depolarizing/reversible/competitive:
i) Suxamethonium
ii) Decamethonium
B. Ganglion blocking drugs:
a) Quaternary ammonium compound:
i) Hexamethonium
ii) Tetraethyl ammonium
b) Tertiary ammonium compound
Trimethapan
c) Secondary ammonium compound
Mecamylamine

pg. 1
 AUTONOMIC PHARMACOLOGY
Adrenergic Antiadrenergic
1. Directly acting: 1. Centrally acting:
A. Non selective: i) α-Methyl dopa
i) Adrenaline ii) Clonidine
ii) Nor-adrenaline 2. Peripherally acting:
iii) Dopamine a) Ganglion blocker:
iv) Isoprenaline i) Hexamethonium
B. Selective: ii) Mecamylamine
i) α 1 selective: b) Neuron blockers:
 Phenylephrine i) Guanethidine
 Methoxamine ii) Reserpine
ii) α 2 selective: iii) Bretylium
 Clonidine c) Receptor blocker:
i) α receptor blocker:
 Methylnorepinephri
α selective:
ne
iii) β  Prazosine
1 selective:
 Terazosine
 Dobutamine
 Tamsulosin
 Isoproterenol
β Non selective:
iv) 2 selective:
 Phentolami
 Salbutamol
ne
 Terbutaline
 Phenoxy-
 Fenoterol Benzamine
2. Indirectly acting: ii) β receptor blocker:
i) Amphetamine Cardio-selective(
ii) Tyramine β 1 selective)
iii) Hydroxy amphetamine
 Atenolol
iv) Amitryptyline
v) Selegiline  Bisoprolol
vi) Enta-capone  Acetbutolol
3. Mixed:  Esmolol
i) Ephedrine Non selective
ii) Metaramenol  Propanolol
 Pindolol
 Timolol
β 2 selective
Butoxamine
iii) Both α and β receptor
blocker:
 Carvedilol
 Labetalol
 Medroxalol
CVS DRUGS
pg. 2
Anti-hypertensive Anti-angina Anti-heart failure
1. Diuretics: 1. Nitrates 1.Positive
i) Frusemide a) Short inotropes:
ii) Hydrochlorothi
zid
acting: a) Cardiac
2. Calcium channel blockers: Glyceryl glycosides:
i) Amlodipine tri-nitrate i) Digoxin
ii) Nifedipine b) Long ii) Digitoxin
iii) Verapamil acting: i) iii)Oubain
3. ACE Inhibitor:
i) Ramipril
Isosorbide b)Phosphodiesteras
ii) Captopril di-nitrate e inhibitor:
iii) Enalapril ii)Isosrbide Amrinone
4. Ang II receptor blocker: mononitrat β 1 agonist:
i) Losartan e Dobutamine
ii) Candesartan
iii) Valsartan
iii)Erythrit 2.Without positive
(BAND) yl tetra inotropic effects:
iv) Omelsartan nitrate 1.Diuretics
5. Sympatholytic drugs 2. β blockers: Spironolactone
 β adrenergic i)Atenolol 2.ACE inhibitors
antagonists: ii)Metoprolol Ramipril
Atenolol
Metoprolol
iii)Propanolol Captopril
Propanolol 3. Calcium Enalapril
 α adrenergic channel 3.Ang II receptor
antagonists: blocker: blockers:
Prazosine i)Verapamil Losartan
Terazosine ii)Diltiazem Omelsartan
Doxazosin
Tamsulosin
4. K +¿¿ channel 4.Renin inhibitor-
 Both α and β opener: Aliskiren
adrenergic i)Nicorandil 5.Adrenergic
blockers: 5. Antiplatelet antagonist-Prazosin
Labetalol, drug: Labetalol
carvedilol i)Low dose 6.Vasodilators
 Centrally
acting:
aspirin Nitroprusside
α -Methyl dopa ii)Clopidogrel Hydralazine
Clonidine
 Adrenergic
neuron blocker:
Guanethidine
Reserpine
Bretylium
6. Vasodilators:
 Arterial
i) Hydralazine
ii) Minoxidil
 Both arterial
and venous
Nitroprusside

CVS DRUGS
pg. 3
Anti-coagulant Anti-platelet Anti-fibrin/ Anti- Lipid lowering
Fibrinolytic/ arrhythmic agents
Thrombolytic
1.Used in vivo: 1.COX inhibitor: 1.Streptokinase 1.Class I: A.Competitive
A)Parenteral: Low dose aspirin 2.Urokinase a)Ia Na+¿¿ inhibitors of
a)Indirect 2.Glycoprotein 3.Alteplase channel HMG-CoA
thrombin inhibitor: 4.Anistriplase blocker: reductase:
inhibitor: Abei-xi-mab 5.Reteplase Quinidine Lovastatin
i)Unfractionated 3.ADP inhibitor: 6.Recombinant Disopyramide Simvastatin
heparin Clopidogrel prourokinase b)Ib Na+¿¿ Pravastatin
ii)Low molecular Prasu-grel channel Atovastatin
weight heparin- 4.Adenosine blocker: B.Niacin
Enoxaparin reuptake inhibitor: Lidocaine, (Nicotinic
Delteparin Di-pyri-damole Mexiletine acid)
iii)Synthetic 5.Phosphodiesterase c)Ic Na+¿¿ C.Activated
pentasaccharide inhibitor: channel lipoprotein
-Fondaparinux Cilos-tazole blocker: lipase (fibric
b)Direct 6.Inhibitor of TxA2: Flecainide acid
thrombin Dazoxiben Encainide derivatives)
inhibitor: 7.Potent 2.Class II: Gemfibrozil
Hirudin vasodilator: Receptor Phenofibrate
B.Oral Prostacycline regulated Ciprofibrate
Warfarin 8.ADP receptor calcium D.Bile acid
Dicaumarol inhibitor: channel binding resins:
Phenindione Ticlopidine blocker: Colistipol
2.Used in vitro: β Cholestyramine
Heparin -adrenocepto E.Inhibitors of
EDTA r antagonist: intestinal
3.8% sodium Propanolol sterol
citrate Sotalol absorption:
3.In vivo & in 3.Class III: Ezetimibe
vitro: Voltage
Heparin sensitive K +¿¿
channel
blocker:
Bretylium
Amiodarone
4.Class IV:
Calcium
antagonist:
Verapamil

RESPIRATORY DRUGS AND RENAL DRUGS

Respiratory drugs Renal drugs

pg. 4
  Drugs used in bronchial asthma: 1. Osmotic diuretics:
1. Bronchodilator: Mannitol
a) Beta agonist (adrenergic drugs)- Urea
i) Selective β 2 agonist- Inulin
salbutamol, terbutaline, Isosorbide
salmeterol, formomoterol, 2. Carbonic anhydrase enzyme
albuterol, remiterol, inhibitors:
pirbuterol Acetazolamide
ii) Non selective α and β Brinzolamide
agonists: Dorzolamide
Adrenaline 3. Loop diuretics:
iii) Non selective β 1 and β 2 Frusemide
agonist: Torsemide
Isoproterenol Bumetanide
b) Methylxanthines- 4. Thiazide diuretics:
Aminophylline Chlorothiazide
Theophylline Hydrochlorothiazide
Theobremine Indapamide
c) Anti-muscarinic- Metolazone
Ipratropium bromide 5. Potassium sparing diuretics:
Oxytropium i) Aldosterone receptor
Tiotropium blocker-Spironolactone,
2. Anti-inflammatory drugs: Eplerenone
a) Corticosterioides: ii) Sodium channel
 Inhaled: blocker-Triamterene,
Fruticasone amiloride
Beclomethasone
Budesonide
Flunisalide
 Systemic:
Prednisone
Methylprednisolone
 I/V
Hydrocortisone
b) Mast cell stablizers:
Cromolyn, Medocromil
c) Leukotrines antagonists:
Montelucast, Zafrilucast
d) IgE antibody:
Omalizumab

CNS DRUGS
Sedative Analgesic Anti- Anti- Anti- Anti- Anesthetic
hypnotics psychotic depressant epileptic parkinsonism

pg. 5
A.Benzodiazepine A.Opoid: A.Pheno- A.Amine A.Major A.Dopaminer- A.General
a.Long acting: i)Natural thiazines pump anti- gic: anesthetics:
1.Diazepam opium i)Aliphatic inhibitors: convul- 1.Levodopa i)Inhaled
2.Flurazepam alkaloids: side chain: 1.Imipra- sants: 2.Carbidopa anesthesia:
3.Clonazepam 1.Morphine 1.Chlor- mine 1.Pheny- 3.Bromo- a)Volatile
4.Quazepam 2.Codeine promazine 2.Amityp- toin criptine liquids:
b.Intermediate ii) 2.Trifluo- tyline 2.Carba- 4.Ropinirole 1.Halothane
acting: Semisynthetic promazine 3.Nortrip- mazepine 5.Amanta- 2.Enflurane
1.Alprazolam opoids ii)Piperi- tyline 3.Pheno- dine 3.Isoflurane
2.Nitrazepam 1.Diacetyl dine side 4.Clomipra- barbitone 6.Rimanta- 4.Des-
3.Temazepam morphine chain: Mine 4.Val- dine flurane
4.Lorazepam 2.Pholcodeine Thio- 5.Protrip- proate B.Anti- b)Gases:
5.Oxazepam 3.Hydro- ridazine tyline B.Newer muscarinic: 1.Chloro-
6.Chlordiazepoxid morphone iii)Pipera- B.Hetero- drugs: 1.Benztro- propane
e 4.Hydro- zine side cyclics: 1.Lamo- pine 2. N 2 O
c.Short acting codone chain i)Second trigine 2.Benzhexol ii)I/V
1.Midazolam 5.Oxycodone 1.Trifluo- generation 2.Leveti- 3.Biperi- anesthesia:
2.Triazolam iii)Synthetic perazine and sub- racetam dine a)Barbi-
3.Chlorazepate 1.Pethidine 2.Fluphe- sequent 3.Prega- 4.Procycli- turates:
B.Barbiturates 2.Fentanyl nazine agents: balin dine 1.Thio-
a.Long acting: 3.Methadone B.Butyro- 1.Amoxa- 4.Gaba- C.MAO pental Na
1.Phenobarbitone 4.Tramadol phenones: pine pentin inhibitor: 2.Metho-
2.Butobarbitone 5.Sulfentanil 1.Haloperi- 2.Maproti- 5.Oxcar- 1.Selegiline hexital
b.Intermediate B.Non-opoid/ dol line bazepine 2.Rasagiline b)Benzo-
acting: NSAIDS 2.Trifluo- 3.Trazodone D.COMT diazepines:
1.Pentobarbitone i)Strong anti- peidol ii)Newer 3rd inhibitor: 1.Diazepam
c.Short acting inflammatory C.Thio- generation: 1.Enta-capone 2.Mida-
1.Secobarbitone : xanthenes: 1.Vanlafa- 2.Tol-capone zolam
2.Hexobarbitone 1.Aspirin a.Flupen- xine c)Opoids:
d.Ultra-short 2.Diclofenac trixol 2.Mitraza- 1.Morphine
acting: 3.Indo- b.Thio- pine 2.Pethidine
1.Thiopental Methacin thixene 3.Nefazo- d)Propofol
sodium 4.Sulindac D.Other done e)Ketamine
2.Methohexital 5.Piroxicam hetero- C.SSRI: f)Miscella-
C.Newer group: ii)Mild to cyclics: 1.Fluoxe- neous:
1.Zopiclone moderate: 1.Pimozide tine 1.Droperi-
2.Zaleplon 1.Propionic 2.Molin- 2.Paroxe- dol
3.Zolpidem Acid Done tine 2.Eto-
4.Eszopiclone 2.Ibuprofen E.Atypical 3.Sertraline midate
5.Buspirone 3.Ketoprofen anti- 4.Citalo- B.Local
4.Naproxen psychotics: pram anesthetics:
5.Mefenamic 1.Loxapine D.MAO i)Esters:
acid 2.Cloza- inhibitors: 1.Cocaine
iii)Weak: Pine 1.Phenel- 2.Procaine
Paracetamol 3.Risperi- zine 3.Tetracaine
Done 2.Isocarbo- ii)Amides:
4.Olan- xazid 1.Lidocaine
zapine 2.Bupi-
vacaine
3.Prilocaine

AUTACOIDS
Histamine Histamine Serotonin Serotonin Prostaglandin Prostaglandin
agonists antagonists agonists antagonists agonists antagonists

pg. 6
A. H 1 A.First 1.Buspi- 1.Cypro- A.PG E1: A.NSAIDs:
receptor generation: Rone heptadine 1.Al-prostadil 1.Low dose
agonists: i)Ethano- 2.Suma- 2.Ketan- 2.Miso-prostol Aspirin
1.2-methyl lamines: Triptan serin B.PG E2: 2.Cele-coxib
histamine 1.Dyphen- 3.Nara- 3.Ritan- Dino-prostone 3.Rofe-coxib
2.2-pyridyl- Hydramine Triptan serin C.PG F 2α : B.Cortico-
ethylamine 2.Dymen- 4.Riza- 4.Ondan- 1.Bimato- steroid:
B. H 2 receptor Hydrinate Triptan setron prost 1.Cortisone
agonists: 3.Doxilamine 5.Zolmi- 5.Grani- 2.Carbo- 2.Hydro-
1.4-methyl ii)Alky- Triptan serton prost Cortisone
histamine lamines: 6.Tera- 6.Risperi- 3.Dino- 3.Predni-
2.Dimaprit 1.Chlorpheni- serod done prost solone
3.Impromidin ramine maleate 7.Ketotifen 4.Latano- 4.Methyl-
e 2.Brompheni- prost prednisolone
C. H 3 receptor ramine maleate D.PG I 2: 5.Beta-
agonists: iii)Pheno- 1.Ilo-prost methasone
1.α-methyl thiazines: 2.Epo- 6.Dexa-
histamine Promethazine prostanol methasone
2.Imetit iv)Piperazines:
1.Meclizine
2.Cyclizine
3.Hydroxy-
zine
v)Piperidines:
Cyproheptadin
e
B.Second
generation:
1.Loratadine
2.Desloratidine
3.Fexofenadine
4.Cetrizine

OTHERS
Uterine Uterine Anti- Anti- Anti-gout Anti-glucoma

pg. 7
stimulants relaxants migraine rheumatic
(Ecbolics) (Tocolytics) fever
1.Oxytocin 1.β A. Treatment 1.NSAIDs: 1.Acute gout: 1.Cholinomi
2.Ergot adrenorece of acute i)Paracetam i)NSAIDS metic:
alkaloids- ptor migraine ol ii)Corticoster i)Pilocarpine
ergometrin, agonists: headache: ii)Aspirin oides ii)Carbachol
methylergome i)Salbutamo 1.NSAIDS: iii)Diclofen 2.Chronic 2.α agonists:
trine l i)Paracetamol ac gout: i)Epinephrine
3.Prostaglan ii)Ritodrine ii)Aspirin 2.Disease i)Probenicid ii)Brimonidine
dins- iii)Terbutali iii)Diclofenac modificatio ii)Sulfinpyraz 3.β blockers:
Misoprostol, ne 2.Anti-emetic n: one i)Timolol
Dinoprostone 2.Mg or D2 i)Methotrex iii) ii)Betaxolol
(PG E2), sulphate receptor ate Allopurinol 4.Diuretics:
Dinoprost 3.Calcium antagonists: ii)Azathiopr i)Acetazolami
4. channel i)Domperidon ine de
Miscellaneou blocker- e iii)Cyclospo ii)Dorzolamid
s- Nifedipine ii)Metoclopra rine e
ethacridine, 4.PG mide iv)Sulfasala 5.Prostagland
quinine synthesis 3.Serotonin zine ins:
inhibitors- agonist: 3.Response i)Latanoprost
Low dose i)Sumatriptan modificatio ii)Bimatoprost
aspirin, ii)Rizatriptan n:
cele-coxib, 4.Ergot i)Etanercept
hydro- alkaloid: 4.Adjuvant
cotisone. Ergotamine drug:
5.Oxytocin B.Prophylaxi Prednisolon
antagonist- s of e
Atosiban migraine:
1.Serotonin
antagonist:
Pizotifen
2.β-blocker:
Propranolol
3.TCA:
i)Amitriptylin
e
ii)Nortriptylin
e
4.Calcium
channel
blocker:
i)Verapamil
ii)Nifedipine

ENDOCRINE DRUGS

pg. 8
Anti-diabetic Glucocorticoids Hormonal Anti-thyroid
contraceptives
A.Injectable: A.According to A.Oral: 1.Inhibits hormone
Insulin duration of action: 1.Combined OCP: synthesis:
Rapidly acting: 1.Short acting: Estrogen- Propylthiouracil
Insulin lispro Hydrocortisone Ethinylestradiol Methimazole
Insulin aspart Cortisone Progestin- Carbimazole
Insulin glulisine 2.Intermediate Levonorgestrel 2.Inhibit I 2
Short acting: acting: 2.Phase regimen: trapping:
Regular (soluble) Prednisolone Estrogen Thiocyanates-SCN
insulin Methyl prednisolone Progesterone-low in Perchlorate
Intermediate acting: Paramethasone first phase and higher Nitrates
Insulin zinc Triamicilone in 2nd & 3rd phase 3.Inhibit hormone
preparation or lente 3.Long acrting: 3.Minipill: release:
Natural protamine Betamethasone Progestin only I2
Long acting: Dexamethasone 4.Postcoital pill: KI, NaI
Protamine zinc insulin B.According to Levonorgestrel Organic iodide
Insulin glargine potency: +Ethinylestradiol 4.Destroy thyroid
B.Oral: 1.Less potent: Levonorgestrel alone tissue:
1.Sulfonylureas: Hydrocortisone Mifepristone Radioactive I 2:
i)First generation: Cortisone B.Injectable: 131I2

Tolbutamide 2.More potent: Depot medroxy

125 I
2

Chlorpromide Prednisolone progesterone acetate

ii)Second generation: Methyl prednisolone Norethindrone- 123 I 2

Glibenclamide Paramethasone Ethanthate 200mg

Glipizide Triamicilone
2.Biguanides: 3.Most potent:
Metformin Betamethasone
3.Meglitinide: Dexamethasone
Rapaglinide C.According to
Nateglinide source:
4.Thiazolidinediones 1.Natural:
: Hydrocortisone
Rosiglitazone Cortisone
5.α glucosidase 2.Synthetic:
inhibitors: Prednisolone
Acarbose Methyl prednisolone
Miglitol Paramethasone
Triamicilone
Betamethasone
Dexamethasone

GIT DRUGS

pg. 9
Peptic ulcer disease Anti-emetic Anti-constipation Anti-diarrheal
(PUD) (Laxatives)
&Purgative
A.Drugs that decrease 1.5-HT 3 1.Bulk forming 1.Opoid agonists:
HCL secretion: antagonists: laxatives: Loperamide
a. H 2 receptor blocker: Ondansetron Bran sugar Diphenoxylate
Ranitidine Granisetron Psyllium preparation 2.Colloidal
Famotidine Dolasetron Methyl cellulose Bismuth
Nizotidine 2.Surfactant/emollient compounds:
2. D2 receptor
Cimetidine laxatives: Bismuth
b. Proton pump antagonist:
Domperidon Sorbitol subsalicylate
inhibitor:
Omeprazole Haloperidol Lactulose Bismuth subcitrate
Lansoprazole Chlorpromazine Docusate 3.Kaolin & pectin
Esomeprazole 3.Anticholinergic: 3.Irritan stimulant 4.Bile salt binding
Rabeprazole Scopolamine laxatives: resins:
c. Antimuscarinic 4. H 2 receptor Bisacodyl Cholestyramin
drugs: antagonist: Glycerol Colestipol
Pirenzipine 4.Osmotic diuretics: 5.Somatostatin
Diphenhydramine
Telenzipine Na phosphate
B.Neutralization of
Dimenhydramine
Meclizine Mg phosphate
secreted acid: 5.Others:
a.Non systemic antacids: Cyclizine
5.Corticosteroides: Liquid paraffin
Mg trisilicate
Aluminium hydroxide Dexamethasone Glycerin suppository
MgO Methyl prednisolone Enema
b.Systemic antacids: 6.Benzodiazepine: Soap water
NaHCO 3 Lorazepam
C.Enhancement of
mucosal resistant by
various mechanism:
Colloid bismuth
compound-Sub
citrate,sub salicylate
Misoprostol
D. Drugs eradicating
H.pylori:(Triple
therapy)
i)Omeprazole
(20mg)/Pantoprazole
ii)Clarithromycin
(500mg)
iii)Metronidazole(400mg
) or
tetracycline(500mg)
or
Amoxicillin (1gm)

ANTIMICROBIALS

pg. 10
Cell wall synthesis inhibitors Protein synthesis Nucleic acid synthesis
inhibitors inhibitors
A.β lactam antibiotics: A.Acts on 30s ribosomal A.Directly inhibit nucleic
1.Penicillin subunit: acid synthesis:
i)Narrow spectrum: 1.Tetracycline 1.Quinolones
Benzyl penicillin i)Short acting: 2.Newer quinolones
Phenoxymethyl penicillin Teracycline (Fluroquinolones)
Cloxacillin Chlortetracycline i)First generation:
Flucloxacillin Oxytetracycline Norfloxacin
ii)Broad spectrum: ii)Intermediate acting: ii)Second generation:
Ampicillin Demeclocycline Ciprofloxacin
Amoxacillin Methacycline Pefloxacin
Mecillinam iii)Long acting: Ofloxacin
Carboxy penicillin:ticarcillin Doxycycline iii)Third generation:
Uredopenicillin:piperacillin Minocycline Sparfloxacin
2.Cephalosporin B.Aminoglycosides: Gatifloxacin
i)First generation: i)Narrow spectrum: Lomefloxacin
Parenteral:Cefazolin,Cephalolothin Streptomycin iv)Fourth generation:
Oral:Cephalexin,Cephradine Kanamycin Moxifloxacin
ii)Second generation: Amikacin Trovafloxacin
Parenteral:Cefuroxime,cefoxitin Sisomycin B.Indirectly inhibit
Oral:Cefaclor,Cefuroxime ii)Broad spectrum: nucleic acid synthesis or
iii)Third generation: Gentamycin Anti-folate drugs:
Parenteral:Ceftriaxone,Ceftizoxim Tobramycin 1.Sulphonamide
e Neomycin i)Rapidly absorbed and
Oral:Cefixime, Ceftodoxime Paromomycin excreted:
iv)Fourth generation: C.Acts on 50s ribosomal Sulfisoxazole
Parenteral:Cefepime, Cefpirome subunit: Sulfamethoxazole
B.Non-β lactam antibiotics: i)Macrolides: ii) Rapidly absorbed and
i)Bacitracin Erythromycin slowly excreted:
ii)Cycloserine Azithromycin Sulfadoxine
iii)Vancomycin Clarithromycin Sulfadimethoxine
Clindamycin iii)Poorly absorbed
ii)Chroramphenicol sulfonamide:
Sulfasalazine
Sulfaguanidine
Succinyl sulfathiazole

Drugs against specific bacteria, virus, fungus

pg. 11
Anti-tubercular Anti-leprosy Anti-fungal Anti-viral
1.A.5 first line agents: 1.Rifampicin A.Antibiotics: A.Anti-herpes
Isoniazid 2.Dapsone a.Polyenes: virus:
Rifampicin 3.Clofazamine Amphotericin B Idoxurine
Pyrazinamide Hamycin Acyclovir
Ethambutol Nystatin Valacyclovir
Aminoglycoside b.Heterocyclic Famciclovir
B.6 months regimens: benzofuran: Ganciclovir
a.Initial phase (2 Griseofulvin B.Anti-retrovirus:
months): B.Antimetabolites: a.Nucleoside
Isoniazid Flucytosine reverse
Rifampicin C.Azoles: transcriptase
Pyrazinamide a.Imidazole inhibitors:
Ethambutol/Streptomyci (topical) Zidovudine
n Ketoconazole Lamivudine
b. Continuation phase Econazole b.Non-nucleoside
(4 months): Cotrimazole reverse
Isoniazid Miconazole transcriptase
Rifampicin b.Triazole inhibitors:
C.9 months regimen: (systemic) Nevirapine
a.Initial phase (2 Fluconazole Efavirenz
months): Voriconazole c.Protease
Isoniazid Itraconazole inhibitor:
Rifampicin D.Allylamine: Ritonavir
Ethambutol/streptomycin Terbinaafine Atazanavir
b. Continuation phase E.Other topical Indinavir
(7 months): agents: Nelfinavir
Isoniazid Tolnaftate Lopinavir
Rifampicin Undecylenic acid C.Anti-influenza:
2.Second line drugs for Benzoic acid Amantadine
TB: Butenafine Rimantadine
Ethionamide D.Non-selective
Capreomycin antiviral drugs:
Cycloserine Ribavirin
Rifabutin Adefovir
Rifapentin Dipivoxil
Amikacin Tenofovir
Kanamycin

pg. 12
 DRUGS AGAINST PARASITE
Anti-malarial Anti-kala- Anti-filarial Anti-amoebic Anthelmintic
azar
A.According to 1.Antimonia 1.Diethyl A.Tissue A.According to
selective action on l: carbamazine amoebicidal: type of
different phase of Sodium 1 gm (3 tab) a.Nitroimidazole: parasites:
parasitic life cycle: stibogluconat 2.Albendazo Metronidazole a.Chemothera
1.Tissue e (SSG) le 400 mg Tinidazole py of
schizonticides: 2.Diamidine tablet Ornidazole nematodes:
Primaquine : Secnidazole Albendazole
Proguanil Pentamidine b.Emetics: Mebendazole
2.Blood 3.Antifungal  Emetine Pyrental
schizonticides: drugs: hydrochloridepamoate
Chloroquine Amphoterici  Dehydroemeti DEC
Quinine nB ne b.Chemothera
Mefloquine Ketoconazol py of
Fansider e c.Chloroquine trematodes:
3.Gametocides: 4.Others: B.Luminal Praziquantal
Primaquine Miltefosine amoebicidal: c.Chemothera
Chroloquine Paromomyci a.Dichloroacetamide py of cestodes:
4.Radical cure: n derivatives: Niclosamide
Primaquine Allupurinol Diloxanide furoate B.According to
5.Chemoprophylax b.Nitroimidazole that act on
is: derivatives: nerve of
Chloroquine Metronidazole nematodes:
Mefloquine Tinidazole a.Act as
B.According to Ornidazole ganglionic
chemical Secnidazole nicotinic Ach
structures: c.Antibiotics: agonist:
1.4- Tetracycline Levamisole
aminoquinolines: Paromomycin Pyrental
Chloroquine Erythromycin pamoate
Amodiaquine d.Hydroxyquinolone b.Act directly
2.8- : or indirectly as
aminoquinoline: Iodoqinol GABA agonist:
Primaquine e.Other Piperazine
Tafenoquine amoebicidal: c.Act on
3.Phenanthrine Nitazoxanide chloride
methanol: C.Mixed channel:
halofantrine amoebicidal: Ivermectin
Lumefantrine Metronidazole
4.Antimetabolites:
Proguanil
5.Sesquiterpenes:
Artesunate
Artemether

pg. 13
 MISCELLANEOUS
Anti-neoplastic drugs Anti-scabies
Drugs in
anemia/Haematinic
drugs
A.Drugs acting directly B.Drugs altering 1.Permethrin 1.Iron
on cell: hormonal milieu: 2.Sulfar preparations:
1.Alkylating agent: 1.Glucocorticoid: 3.Lindane a.Oral preparation:
a.Nitrogen mustard: Prednisolone 4.Dicophane Ferrous sulfate
Mechlorethamine 2.Estrogen: 5.Benzyl Ferrous fumerate
Cyclophosphamide
Fosfesterol benzoate b.Parenteral
b.Ethylamine:
Thio-TEPA Ethinylestradiol 6.Ivermectin preparation:
c.Alkyl sulfonate: 3.Selective estrogen 7.Crotamiton Iron dextran
Busulfan receptor modulators: Iron sodium
d.Nitrosureas: Tamoxifen gluconate complex
Carmastine Tormifene 2.Vitamin B12
Lomustine 4. Selective estrogen preparations
e.Triazine: receptor down 3.Folic acid
Dicarbazine regulation: preparations
2.Antimetabolites: Fulvestrant 4.Erythropoietin
a.Folate antagonist: 5.Aromatase inhibitors:
Methotrexate
Letrozole
b.Purine antagonist:
6-mercaptopurine Anastrozole
6-thioguanine 6.Anti androgen:
c.Pyrimidine antagonist: Flutamide
5-flurouracil 7.5α reductase
Cytarabine inhibitor:
3.Vinca alkaloids: Finasteride
Vincristine Dutasteride
Vinblastine 8.GnRH analog:
4.Taxanes: Nafarelin
Paclitaxel Triptorelin
5.Epipododophyllo toxin:
9.Progestins:
Etoposide
6.Camptothecin analogs: Hydroxyprogesterone
Tropotecan actatate
7.Antibiotics:
Actinomycin D
Doxorubicin
8.Miscellaneous:
Hydroxyurea
Procarbazine

pg. 14
 SAME DRUG IN DIFFERENT CLASS

DRUGS CLASS
1.Acetazolamide Diuretics, Anti-glucoma, anti-epileptic
2.Tetracycline Antimicrobial, Drug of PUD, Anti-amoebic
3.Doxycycline Antimicrobial, Antimalarial
4.Metronidazole Anti-amoebic, Drug of PUD, Anti-IBD
5.Ethinylestradiol Contraceptive, Anti-neoplastic
6.Allopurinol Anti-gout, Anti-kala-azar
7.Amikacin, kanamycin Aminoglycoside, Second line drug of TB
8.Streptomycin Aminoglycoside, First line drug of TB
9.Buspirone 5-HT agonist, Sedative-hypnotics
10.Benzodiazepine Anxiolytic, Anti-convulsant, Hypnotic,
Anesthesia, Antiemetic (Lorazepam)
11.Barbiturate Anticonvulsant, Muscle relaxant, Anesthesia
12.Amoxicillin Antimicrobial (Penicillin), Drug of PUD
13.Clarithromycin Antimicrobial (Macrolides), Drug of PUD
14.Ketokonazole Anti-fungal, Anti-kala-azar
15.Cholestyramine, Colestipol Lipid lowering drugs, Anti-diarhoeal
16.Salbutamol Drugs of bronchial asthma, Tocolytics
17.Calcium channel blocker Antihypertensive, Anti-angina, anti-arrhythmic,
Tocolytics (Nifedipine), anti-migraine
18.Misoprostol Ecbolics, NSAID, Drugs of PUD, Anti-
constipation
19.Rifampicin Anti-tubercular, Anti-leprosy.
20. β blocker Antihypertensive, Anti-migraine, anti-arrhythmic,
Anti-angina, anti-thyroid
21.Aspirin (Antiplatelet, Antianginal in low dose), NSAID
22.Adrenaline Drugs of bronchial asthma, anaphylactic shock
23.Dopamine Drug of cardiogenic shock, heart failure.
24.Sulfasalazine Sulfonamide, Anti-IBD, Anti-Rheumatic fever
25.Sorbitol Diuretic, Laxative
26.Hydrocortisone Drugs of bronchial asthma, drug of anaphylactic
shock
27.Methyl prednisolone Drug of bronchial asthma, Antiemetic.
28.Promethazine Sedative-hypnotic, local anesthetic, drug of
anaphylactic shock
29.Meclizine Anti-emetic, Drug of motion sickness.
30.Quinidine Anti-arrhythmic, Antimalarial
40.Lidocaine Local anesthetic, anti-arrhythmic.
41.Frusemide, Thiazide, Nitroprusside, Antihypertensive, anti-heart failure.
Captopril, Losartan
42.Amitriptyline Antidepressant, Anti-migraine
43.Ergotamine Ecbolics, Anti-migraine
44.Prenisolone Antineoplastic, anti-gout, anti-rheumatic fever
45.Methotrexate Antineoplastic, anti-rheumatic fever, drug of
psoriasis.
46.DEC, Albendazole Antifilarial, anthelmintic
47.Ivermectin Anthelmintic, Anti-scabies.

pg. 15
pg. 16