Lab Report PDF
Lab Report PDF
What will happen to the hydrophilic and lipophilic part of an active molecule
when dispersed in the water?
When the hydrophilic and lipophilic part of an active molecule is dispersed in
water, the surfactants orientate themselves at the surface in order for the
lipophilic region to be removed from the aqueous environment. This results to a
reduction in surface tension as the water molecules are being replaced by the
surfactant molecules in the surface. In line with this, the forces of attraction
between the surfactant and water molecules are quite low, reducing the
contraction force between the molecules (Attwood & Florence, 2008).
Other than the interaction of the active molecule with water, surfactants may also
adsorb at interfaces between two immiscible liquids such as oil and water. These
surfactants will orientate themselves in such a way that the hydrophilic part
interacts with water and the lipophilic part interacts with oil. Due to such similar
imbalance of attractive forces, the interfacial tension will be reduced from the
adsorption (Attwood & Florence, 2008).
References:
Cationic surfactants | STOCKMEIER Chemie. (2020). STOCKMEIER Holding.
https://www.stockmeier.com/en/products/chemical-distribution-production/
specialty-chemicals/home-industrial-care/cationic-surfactants/
Florence, A., & Attwood, D. (2008). Physical Pharmacy: Fast Track. PharmaPress.
https://www.pharmpress.com/files/docs/FTphyspharm_sample.pdf
Hirsch, M. (2018, July 11). Surface Active Agents (Surfactants): Types and
Applications. Prospector Knowledge Center. https://knowledge.ulprospector.com/
3106/pc-surface-active-agents-surfactants/