JAWAHARLAL INSTITUTE OF POSTGRADUATE

MEDICAL EDUCATION & RESEARCH

(An Institution of National Importance under
Ministry of Health & Family Welfare, Govt. of India)
Dhanvantri Nagar, Puducherry – 605 006.

MBBS Revised Curriculum

Phase – II
(Approved by 11th Standing Academic Committee, JIPMER)

2018

Page 1 of 94
 CURRICULUM COMMITTEE

1. Dean (Academic) Chairperson

2. Head of the Department of Anatomy Member
3. Head of the Department of Biochemistry Member
4. Head of the Department of Physiology Member
5. Head of the Department of Microbiology Member
6. Head of the Department of Pathology Member
7. Head of the Department of Pharmacology Member
8. Head of the Department of Forensic Medicine Member
9. Head of the Department of P & SM Member
10. Head of the Department of Medicine Member
11. Head of the Department of Paediatrics Member
12. Head of the Department of Surgery Member
13. Head of the Department of Obst. & Gynae. Member
14. Head of the Department of Psychiatry Member
15. Head of the Department of Dermatology Member
16. Head of the Department of Orthopaedics Member
17. Head of the Department of ENT Member
18. Head of the Department of Ophthalmology Member
19. Head of the Department of Anaesthesiology Member
20. Prof. & Head, Department of Medical education Member
21. Faculty(Academic) Member Secretary

Page 2 of 94
 ACADEMIC AFFAIRS MEMBERS

1. Director Chairman
2. Dean (Academic) Member Secretary
3. Faculty (Academic) Member
4. Controller of Examinations Member
5. Assistant Controller of Examinations Member
6. HOD of Medical Education Member
7. Professor (Examinations) Member

Page 3 of 94
 ACKNOWLEDGEMENT
A curriculum is considered as the “heart” of any learning institution which
means that any college or university cannot exist without a curriculum. With its
importance in formal education, the curriculum has become a dynamic process
due to the changes that occur in our society. Curriculum reform is a challenging
and difficult task. Even the effort to ascribing a single definition to curriculum is
difficult. Curriculum serves as a body of knowledge to be transmitted. It is also
viewed as a process, and as praxis.
I express my heartfelt gratitude to the Director, JIPMER who inspite of
being extraordinarily busy in his schedule spared his valuable time for providing
guidance in making reforms in this curriculum.
I take this opportunity to express my deepest gratitude to
Dr.D. Kadambari, HOD of Medical Education, Dr. Debdatta Basu, Professor
(Sr.Scale) of Pathology, Dr. Zayapragassarazan. Z, Additional Professor of
Medical Education, Dr. Nanda Kishore Maroju, Additional Professor of Surgery,
Dr. Santosh Kumar, Technical Consultant, Medical Education and Head of the
Departments and faculty members of Microbiology, Pathology, Pharmacology
and Forensic Medicine who earnestly offered their support to develop this
curriculum.

I would also express my thanks to the staff members of academic section

for their support in bringing out this curriculum in an effective manner.

Dr. R.P. SWAMINATHAN

Dean (Academic)

Page 4 of 94
 PREAMBLE
Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER),
Puducherry, under Government of India since the year 1956, is one of the leading Medical
Institutions of India. Spread over a sprawling 195 acre campus in an urban locale of
Puducherry (formerly Pondicherry), The Institute was functioning under the administrative
control of Directorate General of Health Service, Ministry of Health and Family Welfare,
New Delhi On 14-7-2008 JIPMER has been declared as an “Institution of National
Importance” by an Act of Parliament, JIPMER, Puducherry. A copy of the Act was Gazette
notified on 14-7-2008.In order to demonstrate high standard of medical education on par
with international level JIPMER is empowered to set patterns in Undergraduate and
Postgraduate Medical Education in all its branches to encourage experiments in the
curriculum as per the act and it is outside the jurisdiction of Medical Council of India. The
Institution is now empowered to award Medical Degrees, Diplomas, etc., under the clauses
23 & 24 of the said Act. Such Degrees / Diploma, etc., shall be deemed to be included in the
schedules to the respective Acts governing Medical Council of India, Indian Nursing Council
and Dental Council of India, entitling the holders to the same privileges as those attached to
the equivalent awards from the recognized Universities of India.
JIPMER imparts Undergraduate (UG), Postgraduate (PG) and Super Specialty
Medical Training through a working hospital (JIPMER Hospital) with bed strength of
2134.Undergraduate degrees M.B.B.S., B.Sc. Nursing, B.Sc. Allied Medical Sciences and
post graduate degrees M.Sc., M.D., M.S are offered in 43 disciplines. Super specialty
courses (D.M./ M.Ch.) are offered in the following disciplines (Cardiology, Neurology,
Cardiothoracic Surgery, Neurosurgery, Urology, Plastic Surgery, Pediatric Surgery, Pediatric
Critical care, Neonatology, Clinical Immunology, Clinical Pharmacology, Nephrology,
Medical Oncology, Endocrinology, Surgical Oncology, Cardiac Anaesthesia, Medical
Gastroenterology and Surgical Gastroenterology). In addition to this Post-Doctoral
Fellowship courses are also offered in 12 disciplines. Full-time Ph.D. Programs are also
available in eleven disciplines as on date. Master of Public Health& Post Basic Diploma
Courses in Nursing were started in January 2014. JIPMER also has started its outreach
campus at Karaikal with an intake of 50 students for MBBS course, from the academic
session 2015-16.

Page 5 of 94
 CONTENTS

SL. PAGE
SUBJECT
NO NO.
1 OUTCOMES OF MBBS COURSE 7
2 GUIDELINES FOR IMPLEMENTATION 8
3 ANNUAL TIMETABLE 9
4 SYSTEMS - BASED & TEMPORALLY SYNCHRONISED TOPICS 10
5 TIME TABLES 72
6 LEARNING RESOURCE MATERIALS 77
7 LAB PROCEDURAL SKILLS 80
8 EXAMINATION REGULATIONS 82
9 ANNEXURE -I – MODEL QUESTION PAPERS 83

Page 6 of 94
 1. OUTCOMES FOR MBBS COURSE
A. GOAL
Developing graduates who are capable of independently rendering comprehensive
primary healthcare and well versed with fundamentals of course disciplines.

B. ENTRUSTABLE PROFESSIONAL ACTIVITIES

1. Diagnosing and managing common Clinical Presentations
2. Diagnosing and providing first-line care for medical and surgical emergencies
3. Performing general medical procedures
4. Defining and managing common health problems of the community
5. Implementing National Health Programmes
6. Participating in health quality improvement initiatives

C. COMPETENCIES
1. Medical expertise
2. Communication
3. Collaboration
4. Professionalism
5. Health advocacy
6. Leadership
7. Scholarship
D. LIST OF CLINICAL PRESENTATIONS (Appendix1)
E. ESSENTIAL SKILLS LIST FOR MBBS (Appendix2)
F. OBJECTIVES FOR EACH DEPARTMENT
1. To learn fundamentals of the discipline
2. To enable achievement of JIPMER MBBS Curricular Goal

Page 7 of 94
 2. GUIDELINES FOR IMPLEMENTATION OF MBBS PROGRAMME
A. OVERALL GUIDELINES
1. Competencies and skills to be facilitated and assessed by formative and summative exams
throughout the course to enable achievement of capability to render comprehensive primary
healthcare.
2. Fundamentals of course disciplines to be facilitated and assessed by formative and summative
exams throughout the course to enable further studies in various disciplines.
3. Integrated Learning to be facilitated by systems-based temporally synchronized teaching- learning
and intra-departmental horizontal and vertical correlations of content.
4. Adult learning principles to be followed in teaching-learning and student centered learning strategy
to be used.
5. A minimum of 10% of simple theory content in a module to be assigned for self-directed learning.
Peer-assisted learning to be used.
6. Early clinical exposure to be used in Phase I. Teaching-learning of Basic Sciences to be included
in Phase III.
7. Electives to be included in Phase III.
8. Student doctor method of clinical teaching to be incorporated.
9. Skills to be acquired and certified in skills lab, diagnostic lab and clinical areas.
10. E-learning methods to be used.
11. A Foundation Course to be conducted before MBBS Phase I.
12. Existing time-frame and teaching hours to be maintained.
13. Departmental identities to be maintained in teaching-learning program, examinations and mark
sheets.
B. GUIDELINES FORTEACHING-LEARNING
1. Lectures to include active learning strategies.
2. Practicals to emphasize individual learning of skills.
3. Clinical teaching to emphasize individual learning of skills.
4. Skills lab to be used for skills learning.
5. Self-learning to be promoted by use of e-learning. Peer assisted learning to be promoted through
discussions.
6. Spiral curriculum model to be used in clinical teaching-learning which has first cycle in Phase I,
second cycle in Phase II and third cycle in Phase III.
7. Student doctor method to be used in clinical teaching using Reporter-Interpreter- Manager-
Educator (RIME)strategy
C. GUIDELINES FORASSESSMENT
1. Skills to be assessed and certified in skills lab and in practical and clinical sessions using
performance criteria.
2. Assessment methods to include assignments, projects, portfolios, MCQs, OSPE and OSCE.
D. GUIDELINES FOR PROGRAMME EVALUATION
Programme evaluation to be done throughout the course.
E. GUIDELINES FOR STUDENT SUPPORT
Student support to be provided throughout the course.
F. GUIDELINES FOR FACILITATION OFIMPLEMENTATION
Central facilitation to be provided throughout the course.

Page 8 of 94
 3. ANNUAL TIMETABLE

Departments of Microbiology, Pathology, Pharmacology and Forensic Medicine

Module Name of Module Week and Class Nos Duration
1-7
 General module Class nos.
1  Immunological system 1-14-Micro 7 weeks
SPANDAN HOLIDAYS 1-18- Path
17-Pharm
First Internal assessment test (approximate period- middle of September)- week 8
9-14
Class nos.
 General module
1 cont’d. 15-36- Micro 6 weeks
 Immunological system
19-36- Path
18-36- Pharm
Second Internal Assessment Test (approximate period- middle of November)- week 15
Winter vacation- December
Hematological system
16- 25
Respiratory system
2 Class nos. 10 weeks
Autonomic nervous
37-67
system
Third Internal Assessment Test (approximate period- beginning of February)- week 26
27- 32
 Gastrointestinal system
3 Class nos. 6 weeks
 Cardiovascular system
68-86
Fourth Internal Assessment test(approximate period beginning of April) week- 33
Summer vacation- May
34- 39
 Genitourinary system
4 Class nos. 6 weeks
 Central nervous system
87-104
Fifth Internal Assessment test (approximate period end of July) week- 40
Endocrine system 41-50
5 Miscellaneous Class nos. 10 weeks
SPANDAN HOLIDAYS 105- end
Internal Assessment test (approximate period end of September/ beginning of October)
week-51
Revision classes – week 52-53
Send up examination
Preparatory holidays
Exit examination

Number of the weeks mentioned is only approximate and subject to change based on holidays.

Page 9 of 94
 4. SYSTEMS - BASED & TEMPORALLY SYNCHRONISED TOPICS
Sl. Forensic
Microbiology Pathology Pharmacology P&SM Medicine Surgery
NO medicine
1. General module and Immunological system
Nutrition –
Macronutrien
Introduction& Introduction History
Introduction of Introduction of Introduction and t&
1. History of on Practice of of
Pathology Pharmacology History Micronutrient
Microbiology Medicine Surgery
s, trace
elements
Processing of
Nomenclature
samples and Introduction
2. Microscopy &Sources of
laboratory and History-2
Drugs
issues

Structure of Cell injury Routes of Drug Medical

3. Bacteria I ( 5classes) Administration Jurisprudence 1

Negligence,
Patient
autonomy,
Balanced diet, conflict of
Structure of Pharmacokinetic Medical Wound
4. Cell injury 2 dietary goals interest,
Bacteria II s–1 Jurisprudence 2 healing
and RDA Confidentialit
y, Informed
consent,
Euthanasia

Classification,
Nomenclature Pharmacokinetic Medical
5. Cell injury 3
and bacterial s–2 Jurisprudence 3
metabolism

Growth,
nutrition and Pharmacokinet Medical
6. Cell injury 4
Cultivation of ics – 3 Jurisprudence 4
bacteria
Genetics –
Basic
(modes of
Sterilization inheritance, Wound
Pharmacodyn Medical Nutritional
7. and Cell injury 5 pedigree, healing
amics – 1 Jurisprudence 5 assessment
Disinfection I clinical 2
application
and
counseling
Sterilization
and
Disinfection
II SDL – Inflammation Pharmacodyn Medical
8. Sterilization and repair (6) amics – 2 Jurisprudence 6
controls and
disinfectant
testing

Page 10 of 94
 Adverse Drug
Reactions, Drug
Inflammation and Interactions, Medical
9. TUTORIALS
repair 2 Bioassay & Jurisprudence 7
Biostandardisati
on

Nutritional Nutritional
Bacterial Inflammation and Drug Discovery deficiency, assessment Fluid
10. Identification 1
genetics I repair 3 & Development public health and balance 1
problem requirements

Bacterial
genetics II
Approach to
SDL- Inflammation
11. NSAIMs – 1 Identification 2 infectious
bacteriophage and repair 4
diseases
s and
bacteriocins

Molecular
Diagnosis in Inflammation and
12. Infectious NSAIMs – 2 Identification3
repair 5
Diseases
Approach to
infectious
Food
Pathogenesis of diseases -
Inflammation and Histamine Death fortification Fluid
13. infectious diagnostic
repair 6 &Antihistamines /Thanatology 1 and balance 2
Disease– I and
adulteration
therapeutic
principles
Pathogenesis Serotonin
Hemodynamics Death /
14. of Infectious agonists &
5 Classes Thanatology 2
Disease –II antagonists

Introduction to
immunology
Hemodynamics Pharmacothera Death /
15. and anatomy
2 py of migraine Thanatology 3
of the immune
apparatus
Drugs
affecting Introduction
Innate Hemodynamics Death / Nutritio
16. Immunity peptide to Medical
3 Thanatology 4 n1
derived Sociology
autacoids
Drugs
Hemodynamics affecting lipid Death /
17. Antigens
4 derived Thanatology 5
autacoids
Drugs for
Hemodynamics Death /
18. Antibodies treatment of
5 Thanatology 6
shock

Page 11 of 94
 Approach to
infectious
Behaviour, diseases -
Humoral
Drugs for Culture, diagnostic
immune Immunology
rheumatoid Medico legal Role of and Nutritio
19. response Hypersensitivity
arthritis & Autopsy 1 family in therapeutic n2
SDL- reactions 1
gout– 1 health and principles;
complement
disease Immune
defence
mechanisms
Drugs for
Cellular
Hypersensitivity rheumatoid Medicolegal
20. immune reactions 2 arthritis & Autopsy 2
response
gout– 2
Antigen Essential
Medicolegal
21. antibody Autoimmunity 1 Medicines &
Autopsy 3
reaction I P drugs
Metabol
Social ic
Alterations
Modern security, respons
Antigen in
SLE and mortuary and psychology e to
22. antibody Chelating agents Temperatur
others 2 Autopsy Room and social trauma
reactions II e, Fever
Hazards organization and
patterns
s surgery
1
Pain –
Immunosuppre Pathophysiolo
Transplant
Immuno ssant And gy, Clinical
23. prophylaxis and tumor Injuries 1
Immunomodul types,
immunity1
ators Assessment,
Management
General
Immunodeficien principles of
24. TUTORIALS Injuries 2
cy – Primary antimicrobial
use – 1
Metaboli
Secondary
General Alteration c
Overview of immunodeficien
principles of Introduction in Pulse response
25. bacterial cy- AIDS Injuries 3
antimicrobial to RCH and Blood to trauma
infections I Pathogenesis
use – 2 Pressure and
and pathology
surgery 2
Overview of Weight Loss
Anthelmintic
26. bacterial Amyloidosis Injuries 4 and Weight
drugs – 1
infections II Gain
Overview of Genetics and
Anthelmintic Firearm Injuries
27. bacterial Metabolic
drugs – 2 1
infections III diseases 1

Page 12 of 94
 Antimicrobial
agents and
Genetics and Dyspnea,
mechanisms Antifungal Firearm Injuries Maternal Infection
28. Metabolic Chest Pain,
of agents – 1 2 Health s1
diseases 2 Palpitation
antimicrobial
resistance

Antimicrobial
Genetics and
susceptibility Antifungal Firearm Injuries
29. testing and Metabolic
agents – 2 3
diseases 3
interpretation

Overview of Penicillin and

Neoplasia (6 Regional Injuries
30. viral Cephalosporins -
classes) 1
infections I 1

Cough,
Overview of Penicillin and
Regional Injuries Haemoptysis, Infection
31. viral infections Neoplasia 2 Cephalosporins– Newborn care
2 Cyanosis, s2
II 2
Clubbing
Overview of
Thermal Injuries
32. viral Neoplasia3 Sulfonamides
1
infections III
Overview of
Aminoglycoside Thermal Injuries
33. parasitic Neoplasia 4
s 2
infections I
Herpes
Overview of zoster,
Thermal Injuries
34. parasitic Neoplasia 5 Macrolides Child health EBV, Burns 1
3
infections II CMV,
HHV-8
Overview of
Transportation
35. fungal Neoplasia 6 Tetracyclines
Injuries
infections I
Nutritional
diseases 1(PEM
Overview of Explosion
and obesity) Fluoroquinolone
36. fungal Injuries and Fall Burns 2
Vitamin s
infections II from Height
deficiency to be
taught as SDL

Page 13 of 94
 2. Hematological system, Respiratory system & Autonomic nervous system
Pallor,
Bleeding,
Hematology –
Haem – 1 – Drugs for Medico-legal Thrombosis,
Introduction, Indicators of
1 Sepsis and treatment of Aspects of Splenomegal
BM, cell counts MCH care
CRBSI anemia – 1 Injuries y,
etc
Lymphadeno
pathy

Decompression,
Drugs for
Haem – 2- Radiation and
2 RBC disorders 1 treatment of
Enteric fever Altitude
anemia – 2
Sickness

Haem – 7- Drugs for

Starvation
3 Trypanosomi RBC disorders 2 trypanosomiasi Burns 3
Deaths
asis s
End of III Semester- One week of exam (Theory and Practicals)
HIV –
Definitions,
transmission
School ,
Haem – 6 – Drugs for
4. RBC disorders 3 Asphyxia Health epidemiolog Shock 1
Leishmaniasis Leishmaniasis
Program y, clinical
manifestatio
ns,
diagnosis
Haemo
parasites (plus
integrated HIV and
Haem – 8 – Drugs for
5. during Micro Asphyxia 2 opportunisti
Malaria- I malaria 1
classes) c infections
Malaria, Kala
Azar, Filaria)

Haem – 9 – Drugs for

6. Malaria - II RBC disorders 4
malaria 2

Infectious
Managemen
Haem – 3 – Drugs for disease
7. RBC disorders 5 Asphyxia 3 t of HIV/ Shock 2
Brucellosis malaria 3 epidemiology
AIDS
-1
Haem – 4 –
Leptospirosis Bacteremia,
and Fibrinolytic & sepsis, SIRS,
8. RBC disorders 6 Asphyxia 4
Borreliosis Antifibrinolytics MODS,
Listeriosis – Septic shock
SDL
Haem – 5 –
9. Rickettsia WBC 1 Anticoagulants 1
infections

Page 14 of 94
 Infectious
Haem – 10 -
Anticoagulants – disease
10. Schistosomias WBC 2 Asphyxia 5 Malaria Shock 3
2 epidemiology
is
-2
Haem – 11 – Brucellosis,
Anticoagulants –
11. Lymphaticfilar WBC 3 Asphyxia 6 Plague,
3
iasis Anthrax
Haem – 12 –
Antiplatelet
12. Dengue and WBC 4
drugs
chikungunya
Clostridial
Misc – infections -
Approach
12Viral Drugs used in Tetanus, gas
13. WBC 5 Asphyxia 7 Malaria to Chest
hemorrhagic dyslipidemia gangrene,
trauma 1
fever botulinum,
CDAD
Haem – 13 – Introduction to Filariasis;
Platelets and
14. Systemic Autonomic Asphyxia 8 Leishmanias
coagulation 1
mycosis Nervous System is
Directly Acting
Haem – 14 – Platelets and
15. Cholinergic
Candidiasis coagulation 2
Drugs
RS – I – Hemorrhagi
Defence c fevers
Virginity, Approach
mechanisms Platelets and Cholinesterase Dengue, (Dengue);
16. Pregnancy and to Chest
of respiratory coagulation 3 Inhibitors Filaria and JE Leptospirosi
Delivery trauma 2
tract and s; Rickettsia
normal flora infection
Common
RS – 2 – URI - fungal
1– infections
Streptococcal Platelets and Anticholinergic– (Candida,
17. Abortion
infections coagulation4 1 Aspergillus,
SDL- Mucor,
enterococci Cryptococcu
s)
Blood
RS – 3–URI - Anticholinergics
18. 2-Diphtheria banking 3
–2
classes
Introduction
RS – 4 –URI –
to Blood
3– Adrenergic Infanticide and
19. Blood banking 2 demography Pneumonia transfusio
Haemophilus Drugs – 1 Child Abuse
andvital n
and Bordetella
statistics
RS – 5 – URI -
4 – Sinusitis
Blood Adrenergic Impotence and
20. and otitis Influenza
banking 3 Drugs – 2 Sterility
including
zygomycosis

Page 15 of 94
 RS – 6 – URI –
5- Viral upper
respiratory
Lymph nodes and
infections- Antiadrenergics
21. spleen (3 classes)
Rhinovirus, –1
1
adenovirus and
infectious
mononucleosis
Anorexia,
RS – 7 –LRI Nausea,
Fertility and Lymphno
-4 –ILI and Antiadrenergics– Sexual Vomiting,
22. orthomyxovir LN 2 Mortality deswellin
2 Jurisprudence 1 Abdominal
indicators g
us Pain,
dysphagia
Treatment of
RS – Diarrhoea,
Alzheimer’s Sexual
23. 8Paramyxovir LN/spleen 3 Constipation,
Disease & Jurisprudence 2
uses G.I.Bleeding
Glaucoma
Respiratory 6
(Including
RS – Antitussives,
Pneumoconiosis
24. 9Paragonimia mucolytics &
which was being
sis expectorants
covered in Gen
Path
RS –10 –
Pneumocystis Acute
Drugs for
jirovecii, Acute infectious Approach
treatment of Sexual
25. Aspergillosis Respiratory 2 Respiratory diarrhoeal to arterial
bronchial asthma Jurisprudence 3
and other Infection diseases - disease
–1
fungal overview;
pneumonias
Food
poisoning
RS- Drugs for and toxin
11Pneumococ treatment of Sexual mediated
26. Respiratory 3
cal bronchial asthma Jurisprudence 4 diarrhoea
pneumonia –2 (Cholera);
Traveller's
diarrhoea
RS-12 typical
pneumonia
Drugs for Approach
Mycoplasma
27. Respiratory 4 treatment of to venous
Chlamydophiil
tuberculosis -1 diseases
a and
Legionella

RS-13 Drugs for

28. Tuberculosis Respiratory 5 treatment of Forensic science Tuberculosis
NTM – SDL tuberculosis -2
RS – 14-
Ventila tor Skeletal Muscle Analytical
29. Associated Respiratory 6
Relaxants Forensics
Pneumonia

Page 16 of 94
 Misc-
Approach
4Bacteri Environment al
Anticancer Analytical to
30. ology of air, disease 2
agents-1 Forensics 2 Lymphati
water and classes
c diseases
milk
Introduction Enteric
Bioterrorism
Anticancer to fever and
31. SDL- Plague, Env disease 2
agents-2 biostatistics Salmonella
Tularemia
Types of data infections

3. Gastrointestinal system (including Liver, Pancreas) & Cardiovascular system

CVS –
Infective Shigellosis;
endocarditis CVS 5 classes Antihypertensive Forensic EIEC;
1.
and CVS 1 –1 Psychiatry 1 Amoebiasis;
Rheumatic Giardiasis
heart disease
GIT –1 -
Normal
Approach
commensals– Antihypertensive Forensic
2. CVS 2 to cardiac
E.coli, –2 Psychiatry 2
trauma
Klebsiella,
Proteus
Worm
Measures of infestations
GIT–2– central (Hookworm
Shigellosis tendency and ,
Antihypertensive
3. and non CVS 3 dispersion, roundworm,
–3
typhoidal concept of tapeworm,
salmonellosis statistical pinworm,
significance Strongyloidi
asis)

GIT –3– Antihypertensive Forensic

4. Cholera CVS 4
–4 Psychiatry 3

Abdomen
GIT –4– Pain
Jaundice,
Helicobacter and Antihypertensive Abdomen
5. CVS 5 Hepatomegal
Campylobacter, –5 mass
y
Yersinia Weight
changes
GIT –5 –
Antibiotic
Hydatid
associated Acute
Drugs for angina disease;
6. diarroheaa- GIT 1 Diarrheal
-1 Toxoplasm
C.difficile and Diseases
osis
non sporing
anaerobes
GIT – 6 – Drugs for angina
7. Amoebiasis GIT 2
–2

Page 17 of 94
 GIT –
Drugs for Upper GI
7Giardiasis
8. GIT 3 treatment of complain
and
heart failure – 1 ts
Balantidiasis
Urinary
tract
symptoms
(Oliguria,
GIT –8– General anuria,
Intestinal Drugs for Epidemiolog dysuria,
9. coccidian GIT 4 treatment of y – Basic pyuria,
parasites and heart failure – 2 measurement hematuria,
micros poridia of health polyuria,
nocturia,
chyluria
and
enuresis)
GIT – 9 –
Intestinal
helminths- I
Antiarrhythmic
10. cestodes- GIT 5
drugs – 1
D.latum,
Taenia,
Hymenoilepis
GIT- 10
Intestinal
helminths- II
Ascites, Upper GI
Intestinal Antiarrhythmic
11. GIT 6 Edema, complain
nematodes- drugs – 2
Anasarca ts 2
Ascaris,
hookworm,
Trichinella
GIT-11
Intestinal
nematodes-
Trichuris, Diuretics &
12. Enterobius and Liver 1 Study designs
Antidiuretics
Strongy
loidesSDL-
Larvamigrans
GIT-12Viral Drugs used for
13 gastroenteritis Liver 2
peptic ulcer – 1

Upper GI
GIT-13Food Drugs used for Descriptive
14 Liver 3 complaints
poisoning peptic ulcer – 2 study
3
Liver-
15. 1Hepatitis Liver 4 Antiemetics
viruses I
Liver-
2Hepatitis Drugs for
16. viruses Liver 5 treatment of
IISDL- diarrhea
Yellow fever
Page 18 of 94
 End of IV semester
Urinary
tract
infections –
etio
Drugs for pathogenesi Lower GI
Liver 3- General Case control
17. Liver6 treatment of s, types, complain
Echinococcus Toxicology 1 study
constipation clinical ts 1
features,
diagnosis
and
treatment

Liver
4Clonorchis Drugs for
Lower GI
and other treatment of General
18. parasitic Gall bladder complain
inflammatory Toxicology 2
ts 2
infections of bowel disease
liver

Misc - Drugs for

11Organisms treatment of
Exocrine General
19. with amoebiasis,
Pancreas Toxicology 3
Oncogenicpot giardiasis,
ential trichomoniasis

Page 19 of 94
 4. Genitourinary system and Central nervous system

Introduction;
Presenting
problems in
Renal and Hepatobil
GUT-1 Urinary Estrogens & Corrosive Cohort renal diseases
urinary system iary and
1. (Edema,
tract infections 8 classes antiestrogens Poisons 1 study
hypertension, Portal 1
Urinalysis 1
renal failure,
hematuria,
proteinuria )

GUT-2
Bacterial STD-I Oral & Hepatobil
Corrosive
2. Gonorrhoea and Renal 2 injectable iary and
Poisons 2
non gonococcal contraceptives Portal 2
urethritis

GUT-3 Bacterial Progestins & Corrosive

3. STD- II Syphilis Renal 3 antiprogestins Poisons 3

Glomerular
disorders –
overview;
GUT-4Bacterial Nephritic
STD- III LGV, syndrome – Upper
Granuloma Inorganic etiology, urinary
Oxytocics & Intervention
4. inguinale, soft Renal 4 Metallic Irritants types, tract
uterine relaxants study
chancre, 1 pathology, Symptom
Bacterial clinical atology 1
vaginosis features,
diagnosis,
treatment and
complications
Upper
Inorganic urinary
GUT-5 Herpes Androgens &
5. Renal 5 Metallic Irritants tract
viruses antiandrogens
2 Symptom
atology 2
Inorganic
GUT-6 IV-1 Introduction to
6 Renal 6 Metallic Irritants
CNS drugs
3

Page 20 of 94
 Nephrotic
syndrome – Lower
GUT-7 HIV-2 Inorganic causes, clinical urinary
Urinary
7 SDL- Tricho Opioids – 1 Metallic Irritants HIV/AIDS features, tract
Bladder 1
monasv aginalis 4 diagnosis, symptom
complications atology 1
and treatment.
Congenital Lower
infections- Male genital Inorganic urinary
8 1Cytome system – 3 Opioids – 2 Metallic Irritants tract
galovirus and classes 5 symptom
rubella atology 2

CNS – 1-
Mening itis –
Meningococci
and other Inorganic
9 bacterial agents MGT 2 Opioids – 3 Metallic Irritants
of acute 6
pyogenic
meningitis,
brain abscess

Tubular
disorders,
CNS -2 Aseptic Bias & Ischemic
Sedative Organic Irritants - Penile
10 meningitis- viral MGT 3 Confoundin Kidney Disease,
hypnotics – 1 Vegetable 1 lesions 1
and spirochaetal g Drugs and
Toxin induced
nephropathy.
Female
reproductive Sedative Organic Irritants - Penile
11 CNS 3 -Tetanus tract (5 hypnotics – 2 Vegetable 2 lesions 1
classes)FGT 1

CNS-4Parasites
affecting brain- Organic Irritants -
12 1PAM,neurocys FGT 2 Alcohol
Vegetable 3
ticercosis

CNS-5Parasites Headache
Drugs for Somniferous Scrotum
affecting brain- Poliomyeliti (migraine),
13 I1Toxoplasmos FGT 3 treatment of Poisons (Narcotic complain
s vertigo and
epilepsy – 1 Poisons) 1 ts
is dizziness

CNS-6 VIRAL Drugs for Somniferous

CNS
14 INFECTIONS-I FGT 4 treatment of Poisons (Narcotic
Trauma 1
Poliomyelitis epilepsy – 2 Poisons) 2

Page 21 of 94
 CNS-7 VIRAL Drugs for
Inebriants-
15 INFECTI ONS-II FGT 5 treatment of
Alcohol 1
Rabies epilepsy- 3

CNS-8 VIRAL Drugs for

INFECTI ONS- CNS (3 classes) treatment of Inebriants - Seizures, CNS
16 III Arboviral CNS 1 LP and Rabies
parkinsonism Alcohol 2 Syncope Trauma 2
encephalitis infections
–1
Tutorials
CNS-9 VIRAL Dermat
Drugs for
INFECTI ONS- Inebriants— ologic
17 IV Slow viral CNS 2- tumors treatment of
Alcohol 3 system
infections parkinsonism – 2
1
CNS – 10
CNS
Cryptococcal CNS 3 – stimulants & Inebriants -
18 meningitis and degenerative
No tropic Alcohol 4
other fungi disorders
agents
affecting CNS
Breast (2 Association
SSTI-1 Motor and Dermatol
classes)Non- and
19 Staphylococcal Drugs of abuse Barbiturates sensory ogic
neoplastic, Causation
infections disturbances system 2
benign 1 of Disease
Approach
SSTI-2Cellulitis Antiviral agents
Breast to breast
20 and necrotizing (except Deliriants 1
carcinoma 2 complain
fasciitis antiretrovirals)
ts 1

SSTI-3 Myositis Disorders of Antiretroviral

21 Deliriants 2
and gas gangrene skin 1 drugs – 1
Disorders of
skin 2 (
Including SCC, Disturbances
Screening
BCC, of Approach
Spinal and of Disease
SSTI-4 melanoma, Antiretrovir consciousness, to breast
22 Peripheral and types
Anthrax cutaneous al drugs – 2 (brain death complain
Nerve Poisons of
fungal diseases and organ ts 2
screening
like Mycetoma, donation)
bullous lesions
etc)
Diseases of
Drugs used in Thyroid
infancy and
23 SSTI-5Leprosy dermatologic Cardiac Poisons dysfunctio
childhood –
disorders n1
non neoplastic
Drugs
SSTI-6 Tumors of affecting
24 Cardiac Poisons 2
Melioidosis childhood calcium
metabolism

Page 22 of 94
 Drugs
Introduction Rabies and
Endocrine 6 affecting Thyroid
SSTI-7 Surgical to NCD and other
25 classes anterior Cardiac Poisons 3 dysfuncti
site infections Mental encephalitides
Pituitary 1 pituitary on 2
Health (JE, HSV)
hormones
Thyroid &
SSTI-8 anti thyroid Hydrocyanic Acid
26 Poxviruses Thyroid 1
drugs – 1

SSTI-9 Thyroid & Approach

Varicella zoster, antithyroid drugs Asphyxiants to Goitre
27 Thyroid 2
HHV-
–2 1
8,Papovaviruses

SSTI-10 Diabetes 4
Tissue (Integrated Drugs for
War Gases and Risk Approach
nematodes- with endocrine treatment of Bacterial
28 Biological factors for to Goitre
Onchocerca, Loa – and not to be diabetes meningitis
Weapons NCD 2
loa and covered in mellitus – 1
Dracunculus general path)
Drugs for
SSTI- treatment of Agricultural
29 11Superficial Parathyroid 5
diabetes mellitus Poisons
fungal infections
–2
Drugs for Hypocalc
SSTI-12 treatment of Agricultural emia and
30 Subcutaneous Adrenal 6
diabetes mellitus Poisons 2 Hypercal
fungal infections
–3 cemia

Arthralgias,
Misc-1Ocular Skeletal system Alphos
Corticosteroids– (Aluminum Diabetes arthritis and Adrenal
31 infectionsSDL- (3
1 Mellitus myalgias; mass 1
Trachoma classes)Bone1 Phosphide)
Chikungunya
Misc -2Osteo
Corticosteroids– Medicinal
32 myelitis and Bone 2
2 Poisons
septic arthritis
General
Misc- principles of
3Biomedical Adrenal
33 Joints 3 anaesthesia & Drug Dependence
waste mass 2
preanaesthetic
management
medication
Cardio-
Rational use of vascular
Misc-4Hospital Inhaled Drug Dependence Nosocomial
34 Investigations diseases:
infections 1 anaesthetics 2 infections
in Pathology HTN, IHD,
Stroke

Page 23 of 94
 Revision
Classes on
Systemic and
applied Stings and
Misc-5 pathology bites (Snake Musculo
Intravenous Drug Dependence
35 Hospital (Anemia, bite, scorpion skeletal
anesthetics 3
infections 2 Bleeding, sting and system 1
Nephrotic others)
syndrome,
Jaundice,
PUO etc.)1-10
Misc-6 Revision
Antimicrobial Classes on Musculo
Local Drug
36 stewardship and Systemic and skeletal
anesthetics – 1 Dependence 4
rational use of applied system 2
antibiotics 2 pathology
Poisoning -
Applied general
Misc-7 Rational pathology- principles; OP
use of Processing of Local Kerosene Oil poisoning,
37 Microbiological Cancers
samples - anesthetics – 2 Poisoning Carbamate
investigations histopatholog poisoning,
y Organochlorin
e poisoning
Plant poisons
Applied (Yellow
Misc-8Infections pathology- oleander,
in the immune Antipsychotics
38 Processing of Food Poisoning abrus,
compromised –1
samples - cleistanthus
patient s
cytology collinus and
datura)
Applied
Misc -9Rodent pathology- Antipsychotics Anesthetic
39 borne viral Universal work –2 Deaths
infections
precautions
Applied Yellow
Misc- 10 pathology- phosphorus,
Emerging and Clinico Antidepressants Postmortem Paraquat,
40 Re emerging Blindness
pathological –1 Artifacts Corrosives,
infections case Prescription
discussions drug poisoning
Heat related
Misc- 11 Applied
disorders;
Microbiological pathology- Antidepressants Torture and
41 investigations of Radiation
Evaluation of –2 Custodial Deaths
related
a febrile patient anemias
disorders

Page 24 of 94
 Applied
Drugs for
pathology-
treatment of Medico-legal
42 Revision class Evaluation of
mania & bipolar Aspects of HIV
bleeding
disorders
disorders
Applied Drugs for Mass Disaster Drowning and
Road traffic
43 Revision class pathology- treatment of and electrical
accidents
jaundice leprosy Investigation injuries
Legal and
Compliance, Ethical issues in
44 Revision class Autopsy 1
Placebo & FDC Biomedical
Research
Therapeutic
Legal and Ethical
drug
issues in
45 Revision class Autopsy 2 monitoring &
Biomedical
Rational Use of
Research 2
Medicines

End of V semester –send up &exam

Page 25 of 94
 5 SYSTEMS - BASED DEPARTMENTWISE CONTENT
MICROBIOLOGY
1. GENERAL MICROBIOLOGY ANDIMMUNOLOGY
 Introduction & History of Microbiology, Classification, Nomenclature of
bacteria
 Microscopy
 Structure of Bacteria(2)
 Growth, nutrition and bacterial metabolism
 Cultivation and Identification of bacteria
 Sterilization and Disinfection(2)
 Bacterial genetics(2)
 Molecular Diagnosis in Infectious Diseases
 Pathogenesis of Infectious Diseases(2)
 Introduction to immunology and anatomy of the immune apparatus
Theory  Innate Immunity
 Antigens
 Antibodies
 Humoral immune response
 Cellular immune response
 Antigen antibody reaction(2)
 Immunoprophylaxis
 Overview of bacterial infections(3)
 Antimicrobial agents and mechanisms of antimicrobial resistance
 Antimicrobial susceptibility testing and interpretation
 Overview of viral infections(3)
 Overview of parasitic infections(2)
 Overview of fungal infections(2)
 Sterilization controls and disinfectant testing
Theory SDL  Bacteriophages and bacteriocins
 Complement
Demo :
 Microscopy
 Morphology of bacteria
 Culture media and bacterial identification based on biochemical reactions
 Visit to CSSD, sterilization and disinfection
 Anatomy of immune apparatus
 Antigen and antibody reactions
 Molecular diagnosis of infectious diseases
 Collection and transport of specimens
Practical  Antimicrobial susceptibility testing
 Direct examination of samples for bacteria, viruses, parasites and fungi
 Cultivation of viruses and viral inclusions
Practical:
 Simple staining
 Gram staining
 Motility of bacteria by hanging drop
 Gram stain of specimens (CSF, pus, sputum) and interpretation
 Interpretation of AST-problems
 Stool examination for parasites

Page 26 of 94
 2 HEMATOLOGY, RESPIRATORY SYSTEM AND AUTONOMIC NERVOUS SYSTEM
 Sepsis and CRBSI
 Enteric fever
 Trypanosomiasis
 Leishmaniasis
 Malaria(2)
 Brucellosis
 Leptospirosis and Borreliosis
 Rickettsial infections
 Schistosomiasis
 Lymphatic filariasis
 Dengue and chikungunya
 Viral haemorrhagic fevers
 System icmycosis
 Candidiasis
 Defence mechanisms of respiratory tract and normal flora
Theory  URI -1 – Streptococcal infections
 URI -2 –Diphtheria
 URI - 3 – Haemophilus and Bordetella
 URI - 4 – Sinusitis and otitis (including Zygomycosis)
 URI - 5- Viral upper respiratory infections- Rhinovirus, adenovirus and infectious
mononucleosis
 ILI andorthomyxovirus
 Paramyxovirus
 Paragonimiasis
 Pneumocystis jirovecii, Aspergillosis and other fungal pneumonias
 Pneumococcal pneumonia
 A typical pneumonia Mycoplasma, Chlamydophila and Legionella
 Tuberculosis
 Ventilator Associated Pneumonia
 Bacteriology of air, water and milk
 Bioterrorism
 Enterococci
Theory SDL  NTM
 SDL-Plague, Tularemia
Demo:
 Salmonella
 Brucella
 Leishmania
 Plasmodium
 Streptococcus
 Corynebacterium diphtheriae
 Haemophilus
 Tuberculosis and NTM
Practical  Aspergillus – LPCB mount
 Pneumocystis jirovecii
 Diagnosis of VAP- Non fermenters
Practical
 Gram stain
 Albert stain
 Kinyoun stain
 Peripheral blood smear- Leishman/Giemsastain
 LPCB wet mount for fungi

Page 27 of 94
 GASTROINTESTINAL SYSTEM (INCLUDING LIVER AND PANCREAS) AND
3
CARDIOVASCULAR SYSTEM
 Infective endocarditis and Rheumatic heart disease
 Normal commensals–Escherichia.coli,Klebsiella, Proteus
 Shigellosis andnontyphoidalsalmonellosis
 Cholera
 Helicobacter andCampylobacter,Yersinia
 Antibiotic associateddiarrhea-C.difficile and non sporing anaerobes
 Amoebiasis
 Giardiasis andBalantidiasis Intestinal coccidian parasites andmicrosporidia
 Intestinal helminths- Icestodes-D.latum, Taenia, Hymenolepis
Theory  Intestinal helminths- IIIntestinal nematodes- Ascaris, hookworm,Trichinella
 Intestinal nematodes-Trichuris,Enterobius andStrongyloides
 Viralgastroenteritis
 Foodpoisoning
 Hepatitis virusesI
 Hepatitis virusesII
 Echinococcus
 Clonorchis and other parasitic infections ofliver
 Organisms with Oncogenic potential
 Yellow fever
Theory  Larvamigrans
SDL  IntestinalTrematodes
Demo:
 Escherichia.coli, Klebsiella,Proteus
 Shigella
 Vibrio
 Entamaeba,Giardia
 Cestodes
 Trematodes
Practical  Intestinal coccidianparasites
 Intestinalnematodes
 Non sporinganaerobes
Practical:
 Stoolexamination
 Albert stain
 Kinyounstaining
 Gram staining

Page 28 of 94
 GENITOURINARY TRACT, CENTRAL NERVOUS
4
SYSTEM
 Urinary tract infections and CAUTI
 Bacterial STD-I Gonorrhoea and nongonococcal urethritis
 Bacterial STD-IISyphilis
 Bacterial STD-III -LGV, Granuloma inguinale, Soft chancre, Bacterial vaginosis
 Herpes viruses
 HIV-1
 HIV-2
 Congenital infections-1 Cytomegalovirus and rubella
 Meningitis – Meningococci and other bacterial agents of acute pyogenic meningitis,
Theory brain abscess
 Aseptic meningitis- viral and spirochaetal
 Tetanus
 Parasites affecting brain- 1 PAM, neurocysticercosis
 Parasites affecting brain- II Toxoplasmosis
 Viral infections-I Poliomyelitis
 Viral infections-II Rabies
 Viral infections-III Arboviral encephalitis
 Viral infections-IV Slow viral infections Cryptococcal meningitis and other fungi
affecting CNS
Theory SDL  Trichomonas vaginalis
Demo:
 Urinary Tract Infections
 Toxoplasma
 Rabies
 Neisseria meningitidis and N. gonorrhoeae
Practical
Practicals:
 Gram stain

Page 29 of 94
5 SKIN AND SOFT TISSUE INFECTIONS AND MISCELLANEOUS
 Staphylococcal infections
 Cellulitis and necrotizing fasciitis
 Myositis and gas gangrene
 Anthrax
 Leprosy
 Melioidosis
 Surgical site infections
 Poxviruses
 Varicella zoster, HHV-8, Papova viruses
 Tissue nematodes- Onchocerca ,Loa loa and Dracunculus
 Superficial fungal infections
Theory
 Subcutaneous fungal infections
 Ocular infections
 Osteomyelitis and septic arthritis
 Biomedical waste management
 Hospital infections(2)
 Antimicrobial stewardship and rational use of antibiotics
 Rational use of Microbiological investigations
 Rodent borne viral infections
 Approach to a patient with fever
 Infections in the immune-compromised patients
 Emerging and reemerging infections
Theory SDL  Trachoma
Demo:
 Staphylococcus
 Bacillus
 Clostridium perfringens
 Superficial and subcutaneous fungal infections
Practical
Practical:
 Gram stain
 Albert stain
 Kinyoun stain
 Problem based exercises

Page 30 of 94
 PATHOLOGY
CELL INJURY, INFLAMMATION AND REPAIR, HEMODYNAMICS, DISEASES
1 OF IMMUNE SYSTEM, GENETIC AND METABOLIC DISEASES, NEOPLASIA
AND NUTRITIONAL DISEASES
Theory Cell injury :
 Cause and mechanism: Ischemic, Toxic, Free- radical induced, Apoptosis
 Reversible cell injury: Types, morphology, hyaline and fatty change
 Cellular adaptation - Atrophy, Hypertrophy, Hyperplasia, Metaplasia
 Irreversible injury: Necrosis and gangrene
 Calcification: Dystrophic and metastatic
 Cellular accumulations: Protein, glycogen, pigment deposition such as melanin,
bilirubin, hemosiderin and carbon
Inflammation & Repair:
 Acute inflammation: Features, Causes, vascular, cellular events and morphological
variants
 Inflammatory cells and mediators
 Chronic inflammation: Causes, types, non- specific and Granulomatous with
examples
 Wound healing and repair by primary and secondary union and factors modifying
them.
Hemodynamic disorders:
 Oedema: Pathogenesis and types
 Chronic venous congestion: Lung, Liver and Spleen
 Thrombosis and Embolism: Formation, Types and Fate, Effect on tissues
 Infarction: Types and Common sites
 Shock: Pathogenesis, types and morphology
Diseases of immune system:
Introduction ( Correlated with what has been taught in Microbiology)
 Type I Hypersensitivity reaction
 Type II & III Hypersensitivity reaction
 Type IV Hypersensitivity reaction – Transplant rejection
 Auto immunity SLE
 Amyloidosis
 Immunodeficiency -AIDS
Genetics & Metabolic disorders:
 Autosomal & sex linked disorders
 Cytogenetic disorders & diagnosis of genetic disease
 Lysosomal disorders, Marfan syndrome, Ehlers-Danlos, Cystic fibrosis
Neoplasia :
 Growth disturbance - Aplasia, Malformation
 Dysplasia and Intraepithelial Neoplasia including carcinoma in situ, Premalignant
conditions
 Neoplasia: Causes, Classification, Histogenesis and molecular basis, Biological
behaviour,
 Benign versus Malignant, Nomenclature
 Malignant Neoplasms: Grade and Stage, metastasis and invasion
 Carcinogenesis: Environmental carcinogens, viral, chemical, occupational,
hereditary
 Laboratory Diagnosis of cancer, Tumor markers, Paraneoplastic syndromes
 Gross and microscopic features, clinical correlation, mode of spread and prognosis
of common
 benign and malignant tumors
Nutritional diseases :PEM and Obesity
Page 31 of 94
Theory SDL Cell injury
 Role of Ca2+ in cell injury
 Cellular aging
Inflammation & Repair
 Role of arachidonic acid metabolites in inflammation
 Morphological patterns of inflammation
 Fracture healing
Hemodynamic disorders
 Starling law
 Normal hemostasis
 Thrombosis due to hypercoagulability
Diseases of immune system:
 B & T Lymphocytes
 I0 immunodeficiency disorders
 Immunological tolerance
 Natural history of HIV infection
 HIV genome
Genetic & Metabolic disorders
 Lyons hypothesis
 Cytogenetic testing
Neoplasia:
 Tumor immunology
 Is cancer hereditary?
 Occupation &cancer
 Smoking and cancer
Nutritional diseases
 Scurvy
 Rickets
 Beriberi
 Vitamin A deficiency
Practical Cell injury:
 Gross: Pregnant uterus, Cardiac hypertrophy, Brown atrophy heart, Hypoplastic
kidney, Granular contracted kidney
 BPH, Endometrial hyperplasia
 Melanoma, Anthracosis
 Fatty liver, Gangrene foot, intestine
 Caseous necrosis – LN, Lung
 Splenic infarct, Liverabscess
 Slides: Testicularatrophy
 BPH
 Anthracosis, Melanoma, Dystrophic calcification
 Fatty liver
 Caseous necrosis – LN, Myocardial infarct Slides
Inflammation & Repair
 Gross: Pyaemic abscess kidney
 Lobar pneumonia
 Acute appendicitis
 C/C cholecystitis
 C/C pyelonephritis
 TB lung &LN
 Peptic ulcer & Trophic ulcer leg
 Slides: Lobar pneumonia
 Acute appendicitis

Page 32 of 94
  C/C cholecystitis
 Plasma cells
 FB granuloma
 TB granuloma
 Ulcer with granulation tissue
Hemodynamic disorders
 Gross: CVC liver &spleen
 Infarction spleen,lung,heart
 Thrombus
 Slides: CVC liver &spleen
 Infarctionspleen
 Recent & Organizing thrombus
Diseases of immune system:
 Gross: TB lung
 Hashimotothyroiditis
 Amyloid kidney, spleen
 Slides: Eosinophilia
 Spherocytosis(AIHA)
 TB LN
 LE cell
 Hashimoto thyroiditis
 Medullary Ca thyroid
Neoplasia:
 Gross: Characteristics of benign & malignant tumors
 Benign –circumscription,cystic,polyp
 Malig –ulcerative,diffuse,proliferative
 Benign & malig ulcers
 Benign & malig breast tumors
 Invasion – Chorio Ca, Osteosarcoma, Breast Cancer, RCC renal vein invasion
 Metastasis – Gastric & Krukenberg
 Melanoma LN mets
 Vertebral Mets
 Pleural Mets, Liver & Lung mets
 Lipoma, Haemangioma,
 Leiomyoma, Teratoma
 SCCa cervix, penis, oesophagus
 Melanoma foot
 Adenoca stomach, endometrium, colon
 Slides: Anaplasia
 Metastasis –LN,liver
 Lipoma, Haemangioma, Leiomyoma, Neurilemmoma, Teratoma
 SCC,BCC
 Melanoma
 Adenoca

Page 33 of 94
2 HEMATOLOGY, RETICULOENDOTHELIAL SYSTEM, RESPIRATORY SYSTEM
AND ENVIRONMENTAL DISEASES
Hematology:
RBC disorders:
 Constituents of blood and bone marrow, regulation of hematopoiesis
 Anemia: Classification and clinical features, Laboratory approach
 Nutritional anemia: Iron deficiency, Vitamin B12 and Folate deficiency
 Hemolytic Anemia: Classification and Laboratory diagnosis.
 Thalassemia, Hemoglobinopathy like Sickle cell A.
 Hereditary Spherocytosis, G6PDdeficiency
 Acquired hemolytic anemia: Autoimmune hemolytic and Microangiopathic hemolytic
anemia, hemolytic disease of newborn
 Aplastic Anemia, PNH, Pancytopenia, myelopthisic anemia
WBC disorders:
 Leukocytosis, leukemoid reaction
 Leukemia: Acute and Chronic – classification and diagnosis
 Other myeloproliferative neoplasm like CML
 Myelodysplastic syndromes
 Plasma cell disorders
Disorders of platelets and coagulation :
 Hemostatic disorders: Platelet deficiency, ITP
 Coagulation disorders like Hemophilia, Von Willebrand Disease
 DIC
Blood bank and immune haematology:
Theory  ABO & Rh system. Blood grouping, cross matching, Coombs, HDN
 Blood transfusion –donor selection, blood storage, complications
 Rational use of blood, component therapy
Hemoparasites :
 Malaria, Leishmaniasis, Filariasis
Disorders of spleen and lymph node:
 Hodgkin lymphoma, Non Hodgkin lymphoma
Diseases of respiratory system:
 Structure of bronchial tree and alveoli, normal and altered lung function, concept of
obstructive and restrictive lung disease,
 Pneumoconiosis
Inflammatory diseases of lung like Chronic Obstructive Pulmonary disease, Emphysema,
Chronic Bronchitis, Bronchial Asthma, Bronchiectasis
 Pneumonia
 Lung Abscess
 Pulmonary Tuberculosis
 Lung tumors: etio pathogenesis and types
Environmental disorders :
 Hazards of smoking, alcohol &Radiation

Page 34 of 94
 WBC disorders :
 Quantitative /Reactive disorders
Disorders of platelets and coagulation
 Normal hemostasis
 Thrombophilia
Disorders of spleen and lymph node : Splenomegaly, hypersplenism ,reactive
lymphadenopathy
Theory SDL Diseases of respiratory system:
 Diseases of pleura
 Interstitial lung disease
Environmental disorders:
 Deleterious effects of tobacco
 Factors affecting biological effects of radiation
 Lead poisoning
 Deleterious effects of alcohol
RBC disorders:
 Experiment: Visit to lab
 Anticoagulant tubes
 Peripheral smear staining
 Hb estimation
 Red cell indices
 ESR,PCV
 Reticulocyte count
 Slides: Iron deficiency anemia
 Megaloblastic A –PS &BM
 Thalassemia
 Sickle cell Anemia
 Spherocytosis
 Malarial parasites
WBC disorders:
 Experiment:
 DC,TC
 Bone marrow asp needle
 Slides: Neutrophilia, Eosinophilia,
Practical
 Lymphocytosis
 Acute leuk –ALL,AML
 c/c leuk –CLL,CML
 Multiple myeloma
Disorders of platelets and coagulation:
 BT demonstration
 PT, APTT – demonstration in labs
Blood bank and immunohematology:
 Blood bags
 Blood grouping
 Visit to blood bank
Disorders of spleen and lymph node:
 Gross: TBLN
 CVC spleen
 Hodgkin lymphoma
 Slides: TBLN
 CVC spleen
 Hodgkin lymphoma
 Filarial lymph node

Page 35 of 94
Diseases of respiratory system:
 Gross: TB lung-apical, fibro cavitary, military
 Pneumonia-lobar, broncho
 Abscess
 Bronchiectasis
 Ca-IO,2O
 Slides: TB lung
 Bronchiectasis
Environmental disorders
 Gross and slide: Anthracosis and Cirrhosis

Page 36 of 94
3 CARDIOVASCULAR SYSTEM, GASTROINTESTINAL SYSTEM AND
HEPATOBILIARY INCLUDINGPANCREAS
Cardiovascular system:
 Hypertension, Atherosclerosis, Aneurysms
 Ischemic heart disease
 RHD, Infective endocarditis
Diseases of gastrointestinal tract :
 Oral pathology: Leukoplakia, Premalignant conditions and Carcinoma
 Salivary gland pathology: Common benign and malignant tumors,
 Diseases of esophagus: Barrett Esophagus and Carcinoma
 Gastritis – types, H. Pylori infection
 Tumors of stomach: benign and malignant
 Infectious diseases of intestine: Typhoid, Tuberculosis, Amebic colitis, Hydatid cyst,
 Inflammatory bowel disease –Ulcerative
Theory
 Crohn’s disease
 Intestinal tumors: Polyps, Carcinoma, Lymphoma and Carcinoid, Appendicitis
Diseases of liver and gall bladder:
 Jaundice: types, etio pathogenesis, differential diagnosis
 Hepatitis: Acute and Chronic, Pathology
 Cirrhosis: Etiology, classification, Post necrotic, alcoholic, metabolic, Morphology,
complications
 Alcoholic liver disease
 Tumors of liver: hepatocellular carcinoma, metastasis
 Gall bladder diseases: Cholecystitis, cholelithiasis,carcinoma
Diseases of pancreas:
Pancreatitis and tumorscolitis,
Cardiovascular system:
 Congenital heart disease
 Cardiomyopathy
 Pericarditis, Myxoma
Theory Diseases of gastrointestinal tract:
SDL  Oral cavity tumors
 Malabsorption
Diseases of liver:
 Congenital hyperbilirubinemia
 Primary biliary cirrhosis, Primary sclerosing cholangitis
Cardiovascular system:
 Gross: Atherosclerosis,
 Aneurysms-ath, syphilitic
 MI, RHD, Infective endocarditis
 Slides: Atherosclerosis
 MI
 Aschoff nodule
Diseases of gastrointestinal tract :
Practical  Gross: Pleomorphic adenoma
 Ca oesophagus
 Gastric ulcer
 Ca stomach-ulceroprolif, linitis
 TB, Typhoid, Amoebiasis, Hydatid
 Ca colon, multiple polyposis
 Slides: Pleomorphic adenoma
 Gastric ulcer
 Ca stomach

Page 37 of 94
  TB intestine
 Adeno Ca colon
Diseases of liver:
 Gross: Fatty liver, CVC liver, Abscess liver,
 Cirrhosis-micro ,macro with Ca
 Ca 10,20
 Liver biopsy needle
 Slides: Fatty liver, CVC liver
 Cirrhosis
Diseases of gall bladder:
 Gross: Chronic cholecystitis with gallstones
 Slide: Chronic cholecystitis

Page 38 of 94
 4 GENITOURINARY AND CNS
Diseases of urinary tract :
 Renal function tests
 Urinalysis
 Acute and Chronic renal failure, End-stage renal disease
 Glomerulonephritis: Post streptococcal, Crescentic GN
 Secondary renal diseases
 Nephrotic Syndrome
 Acute tubular necrosis
 Urinary tract infection and Pyelonephritis
 Nephrolithiasis
 Renal tumors : Renal cell carcinoma, Wilms Tumor
 Urinary bladder: cystitis, urothelial carcinoma
Theory Diseases of the male genital tract:
 Disease of penis- premalignant and carcinoma, Syphilis
 Nodular hyperplasia of prostate and carcinoma prostate
 Tumors of testis
Diseases of female genital tract:
 Diseases of cervix: Cervical carcinoma, PAP stain, Screening and diagnosis
 Endometrial hyperplasia and carcinoma, Smooth muscle Tumors, Endometriosis
 Trophoblastic diseases: Hydatidi form mole and Choriocarcinoma
 Ovarian tumors
Diseases of CNS:
 CSF and its disturbance
 Inflammatory disorders: Meningitis and Brain abscess
 CNS tumors: Astrocytoma and Meningioma: classification
 Degenerative disorder
Diseases of urinary tract:
 Immunofluorescence of renal diseases
 Polycystic renal disease
 Bladder cancer
Diseases of the male genital tract:
Theory SDL  Mal e infertility and Semen analysis
Diseases of female genital tract:
 Hormonal changes in endometrium
Diseases of CNS:
 PRION disease, Alzheimers
 Subdural and intracranial hemorrhage
Diseases of urinary tract:
 Gross/ Experiment: Urine Analysis
 Polycystic kidney–adult, infantile
 Chronic pyelonephritis
 Hydronephrosis with urolithiasis
 Granular contracted kidney
 RCC, Wilms tumor, Ca bladder
Practical  Slides:RCC
 Chronic pyelonephritis
 Wilms tumor
Diseases of the male genital tract:
 Gross: BPH Ca penis
 Seminoma
 Non seminomatoustrs
 Slides: BPH and Seminoma

Page 39 of 94
Diseases of female genital tract:
 Gross: Ayre spatula ,Ca cervix
 Leiomyoma, Endometrial Ca
 Serous /Mucinous cyst/Ca
 Dermoid cyst
 Krukenberg
 Dysgerminoma
 H mole, ChorioCa
 Slides: Leiomyoma
 Endometrial hyperplasia
 Ovteratoma
 Hmole
Diseases of CNS:
 Gross:
 Meningioma
 LP needle

Page 40 of 94
 5 BREAST, DISEASES OF SKIN, DISEASES OF INFANCY AND CHILDHOOD,
ENDOCRINES, DISEASES OF BONE AND JOINT AND MISCELLANEOUS
Diseases of breast: Fibrocystic d/s, Fibroadenoma, Phyllodes Carcinoma
Diseases of skin:
SCC, BCC, melanoma, Leprosy
Other cutaneous infectious diseases like Mycetoma, Molluscum,
Rhinosporidiosis Diseases Of Infancy and Childhood: Non-neoplastic like
Hydrops fetalis Tumors of childhood
Diseases of endocrine system:
Non neoplastic lesions of thyroid: Thyroid function tests, Iodine deficiency, Goitre,
Autoimmune thyroiditis, Myxedema and thyrotoxicosis Tumors of thyroid
Adrenal diseases: Hyper function and hypo function, Tumors
Theory Parathyroid hyperplasia and adenoma
Pituitary hyper function and hypo function, tumors Multiple endocrine neoplasia
Diabetes Mellitus
Diseases of bone & joints: Osteomyelitis, osteoporosis, Bone tumors
Osteoarthritis, Rheumatoid arthritis, Gout
Miscellaneous:
 Revision Classes on Systemic and applied pathology
 Anemia, Bleeding, Nephrotic syndrome, Jaundice, PUO, bleeding disorder etc
 Processing of samples
 Universal work precautions
 Autopsy
Diseases of skin: Bullous diseases, Psoriasis
Diseases of bone & joints:
Theory  Paget disease of bone, Osteomalacia, Osteoporosis
SDL  Metastatic tumors in bone
Endocrine: Hyper function and hypo function of endocrine organs, Thyroid function tests
Diseases of breast:
 Gross: Fibroadenoma and IDC
 Slide: Fibroadenoma
Diseases of skin:
 Gross: SCC, melanoma, Mycetoma
 Slides: SCC, BCC, Melanoma,
 Mycetoma, leprosy, Molluscum, Rhinosporidiosis
Diseases of endocrine system:
 Gross/ Experiment: MNG, Colloid goiter
 Papillary Ca thyroid
Practical  Pheochromocytoma
 Urinalysis – sugar and ketones
 Slides: MNG
 Papillary Ca
 Medullary Ca
 KW lesion
Diseases of bone & joints:
 Gross: Sequestrum
 GCT
 Osteosarcoma
 Ewings
 Chondrosarcoma, Vertebral mets
 Slides: Osteomyelitis
 GCT
 Osteosarcoma

Page 41 of 94
 PHARMACOLOGY

1 GENERAL PHARMACOLOGY AND IMMUNOPHARMACOLOGY - I

 Introduction to Pharmacology Course

 Nomenclature & Sources of Drugs
 Routes of Drug Administration
 Pharmacokinetics – 3classes
 Pharmacodynamics – 2classes
 Adverse Drug Reactions, Drug Interactions
 Drug Discovery &Development
 NSAIMs – 2classes
 Histamine &Antihistamines
 Serotonin agonists &antagonists
 Pharmacotherapy of migraine
 Drugs affecting lipid derived autacoids
 Drugs for treatment of shock
Theory
 Drugs for rheumatoid arthritis & gout-2classes
 Essential Medicines & P drugs
 Chelating agents
 Immuno suppresants &immune modulators
 General principles of antimicrobial use – 2 classes
 Anthelmintic drugs – 2classes
 Antifungal agents – 2classes
 Penicillins & cephalosporins – 2classes
 Sulfonamides
 Aminoglycosides
 Macrolides
 Tetracyclines
 Fluoroquinolones
 Bioassay and biostandardisation
 Drugs affecting peptide derived autacoids
 General principles of poisoning
 Chelating agents
Theory SDL
 Vitamins
 Miscellaneous cell wall synthesis inhibitors
 Chloramphenicol
 Miscellaneous protein synthesis inhibitors
 Introduction to Practical pharmacology and sources of drugs
 Oral and parenteral dosage forms
 Topical dosage forms and devices
 Parenteral drug administration
 Prescription writing and auditing –Basic concepts
Practical  Prescription writing Autacoids
 Good laboratory practice
 Calculation of drug dosage and percentage solutions
 Data presentation and analysis
 Study of action of drugs on the rabbit'seye – CAL
 Effective doctor-patient communication

Page 42 of 94
 2 DRUGS FOR HEMATOLOGIC DISORDERS, DRUGS AFFECTING RESPIRATORY
SYSTEM AND AUTONOMIC
NERVOUS SYSTEM
 Drugs for treatment of anemia - 2classes
 Drugs for trypanosomiasis
 Drugs for leishmaniasis
 Drugs for treatment of malaria – 3classes
 Fibrinolytics & Antifibrinolytics
 Anticoagulants – 3classes
 Antiplatelet drugs
 Drugs used in dyslipidemia
 Introduction to Autonomic Nervous System
Theory  Directly Acting Cholinergic Drugs
 Cholinesterase Inhibitors
 Anticholinergics – 2classes
 Adrenergic Drugs – 2classes
 Antiadrenergics – 2classes
 Treatment of Alzheimer’s Disease &Glaucoma
 Drugs for treatment of bronchial asthma – 2 classes
 Drugs for treatment of tuberculosis – 2classes
 Skeletal Muscle Relaxants
 Anticancer agents – 2classes
Theory  Antitussives, mucolytics &expectorants
SDL  Coagulants
 Effect of drugs on ciliary movement of frog's oesophagus -CAL
 Effect of drugs on perfused frog's heart - CAL
 Effect of drugs on dog's blood pressure – CAL
Practical
 Bioassay of histamine – CAL
 General principles of anti-microbial use
 Prescription writing Chemotherapy1

Page 43 of 94
 DRUGS AFFECTING CARDIOVASCULAR SYSTEM AND GASTROINTESTINAL
3
SYSTEM
 Antihypertensives – 5classes
 Drugs for angina -2classes
 Drugs for treatment of heart failure – 2classes
 Antiarrhythmic drugs – 2classes
 Diuretics
Theory  Drugs used for peptic ulcer – 2classes
 Antiemetics
 Drugs for treatment of diarrhea
 Drugs for treatment of constipation
 Drugs for treatment of inflammatory bowel disease
 Drugs for treatment of amoebiasis, giardiasis and trichomoniasis
Theory SDL  Antidiuretics
 P drug concept, individualization of drug therapy and pharmacoeconomics
 Study of absorption and bio availability of drugs in man
 Preparation of solution for test dose of penicillin
Practical  Therapeutic drug monitoring
 Critical appraisal of drug advertisements
 Essential medicines list
 Prescription writing Chemotherapy2

4 DRUGS AFFECTING GENITOURINARY SYSTEM AND

CENTRAL NERVOUS SYSTEM
 Estrogens &antiestrogens
 Oral & injectable contraceptives
 Progestins &antiprogestins
 Oxytocics & uterine relaxants
 Androgens & antiandrogens
Theory  Introduction to CNS drugs
 Opioids – 3classes
 Sedative hypnotics – 2classes
 Alcohol
 Drugs for treatment of epilepsy – 3classes
 Drugs for treatment of parkinsonism – 2 classes
Theory SDL  CNS stimulants & Nootropicagents
 Management of common poisonings
 ADR monitoring and causality analysis
 Medical ethics and Informed consent for research on humans
Practical
 Randomized controlled clinical trials
 Fixed dose drug combinations
 Prescription writing CVS

Page 44 of 94
 5 DRUGS AFFECTING ENDOCRINE SYSTEM AND MISCELLANEOUS
 Drugs of abuse
 Antiviral agents (except anti-retrovirals)
 Antiretroviral drugs – 2classes
 Drugs affecting calcium metabolism
 Thyroid & anti thyroid drugs – 2classes
 Drugs for treatment of diabetes mellitus – 3 classes
 Corticosteroids – 2classes
 General principles of anaesthesia & preanaesthetic medication
Theory  Inhaled anaesthetics
 Intravenous anaesthetics
 Local anaesthetics – 2classes
 Antipsychotics – 2classes
 Antidepressants – 2classes
 Drugs for treatment of mania & bipolar disorders
 Drugs for treatment of leprosy
 Compliance, Placebo &FDC
 Therapeutic drug monitoring & Rational Use of Medicines
 Drugs used in dermatologic disorders
Theory SDL  Drugs affecting anterior pituitary hormones
 Medication errors
 Sources of drug information and evidence based drug use
Practical  Prescription writing CNS
 Prescription writing Endocrine system

Page 45 of 94
 FORENSICMEDICINE
1 GENERAL FORENSIC MEDICINE
 Introduction and History
 Inquest
 Police Inquest
 Magistrate Inquest
 Courts of Law
Theory
 Subpoena or Summons
 Conduct Money
 Medical Evidence
 Types of Witness
 Recording of Evidence
Theory SDL  Conduct and Duties of a Doctor in the Witness Box
Practical NIL

2 MEDICAL JURISPRUDENCE AND ETHICS

 State Medical Council(SMC)
 Duties of a Doctor
 Privileged Communication
 Medical Malpractice
 Unethical Acts
 Professional Misconduct (Infamous Conduct)
 Erasure of Name
 Types of Physician-Patient Relationship
 Professional Negligence
 Preventing Medical Litigation
 Defenses Against Negligence
 Doctrine of Res Ipsa Loquitur
 Calculated Risk Doctrine
 Doctrine of Common Knowledge
Theory  Doctrine of Avoidable Consequence Rule
 Medical Maloccurrence
 Novus Actus Interveniens
 Contributory Negligence
 Therapeutic Misadventure/Hazard
 Vicarious Liability/Respondent Superior
 Corporate Negligence
 Products Liability
 Consent
 Medical Records
 Malingering(Shamming)
 Euthanasia (Mercy Killing)
Acts Related to Medical Practice
 The Consumer Protection Act, 1986(CPA)
 The Workmen's Compensation Act,1923
 The Medical Termination of Pregnancy (MTP)Act, 1971
 The Prenatal Diagnostic Techniques (PNDT) Act, 1994 and PCPNDT Act
 The Transplantation of Human Organs Act,1994
Theory
 Medical Council of India(MCI)
SDL
 Functions of MCI
Red Cross Emblem
Practical  Dying declaration
Page 46 of 94
  Consent for Operation
 Discharge Against Medical Advice
 Police Intimation Letter

3 IDENTIFICAT(ION
 Corpus Delicti
 Race and Religion
 Sex
 Nuclear Sexing
 Intersex
 Sex from Skeletal Remains
 Age
 Age from Ossification of Bones
 Age Determination in Adults Over 25Years
 Medico-legal Importance of Age
 Stature
 Anthropometry (Bertillon System)
Theory
 Dactylography(Dactyloscopy)
 Hair
 Superimposition
 Forensic Odontology
 Miscellaneous Methods of Identification
 Scars
 Poroscopy
Theory
 Lip Prints(Cheiloscopy)
SDL
 Tattoo Marks
 Estimation of Age by Bone
 Estimation of Sex by Bone
 Estimation of Stature
 Estimation of Race
 Cluster of Bone Examination
Practical  Forensic Radiology
 Dental Examination
 Age Estimation
 Hair and Fibers
Fingerprint

Page 47 of 94
4 THANATOLOGY AND POSTMORTEM CHANGES
 Brain/Brainstem Death
 Cause, Mechanism and Manner of Death
 Cause of Death
 Modes of Death (Proximate Causes of Death)
 Anoxia
 Sudden Death
 Coronary Atherosclerosis
Signs of Death
Theory  Immediate Changes (Somatic Death)
 Suspended Animation (Apparent Death)
 Early Changes (Molecular Death)
 Cooling of the Dead Body
 Postmortem Staining
 Rigor Mortis
 Cadaveric Spasm
 Heat Stiffening
 Cold Stiffening
 Decomposition/Putrefaction
 Decomposition of Submerged Body
 Floatation of a Dead Body on Water
 Adipocere(Saponification)
 Mummification
 Estimation of Time Since Death (TSD) or Postmortem
 Interval(PMI)
 Preservation of Dead Bodies
 Entomology
Theory SDL  Presumption of Survivorship
Presumption of Death
 Autopsy demonstration
Practical Forensic Entomology

Page 48 of 94
5 MEDICO-LEGAL AUTOPSY
 Purpose/Objectives of Autopsy
 Procedure for Medico-legal Autopsies
 Instruments for Autopsy Examination
 External Examination
 Internal Examination
 Skin Incisions
 Evisceration Methods
 Examination Proper
Theory  Chest
 Heart
 Neck
 Skull and Brain
 Description of an Organ
 Report
 Demonstration of Pneumothorax
 Demonstration of Air Embolus
 Collection of Samples
 Preservation of Viscera
 Preservation of Samples
 Obscure and Negative Autopsy
 Second Autopsy
 Examination of Decomposed, Mutilated and Skeletonized Remains
 Exhumation
Theory SDL  Samples for Laboratory Investigations
Practical  Autopsy demonstration

6 MODERN MORTUARY AND AUTOPSY ROOM HAZARDS

 Criteria of a modern mortuary.
Theory  Commonly Acquired Infections
 Autopsy of HIV Positive and HBV Patients Second Autopsy
Theory SDL  Autopsy and Disposal of Radioactive Corpse Practical
Practical  Autopsy demonstration

7 Injuries
 Classification of Wounds/Injuries
 Abrasion
Theory  Bruise/Contusion
 Lacerated Wound
 Incised Wound
 Chop Wounds
 Stab Wound
 Defense Wounds
 Fabricated Wounds (Fictitious/Forged Wounds)
Theory SDL  Therapeutic or Diagnostic Wounds
Practical  Medical Sickness/Under Treatment Certificate
 Medical Fitness Certificate
 Certificate of Physical Fitness
 Injury / Wound Certificate
 Examination of Weapon

Page 49 of 94
8 Firearm Injuries
 Classification of Firearms
 Rifled Firearms
 Smooth Bore Firearms/Shotguns
 Bore(Gauge/ Calibre)
 Bullet
 Cartridge
 Gun powders (Propellant Charge)
 Mechanism of Discharge of Projectile
Theory  Wound Ballistics and Mechanism of Injury
 Firearm Wounds
 Characteristics of Shotgun Wounds
 Characteristics of Rifled Firearms Wounds
 Firearm Wounds on Skull
 Exit Wounds
 Postmortem Examination
 Preservation and Marking of Exhibits
Theory SDL  Peculiar Effects of Firearms
Practical NIL
9 . Regional Injuries
 Cranio cerebral Injuries
 Soft Tissue Injury
 Skull Fractures
 Coup and Contre-coup Injury
 Brain Injury
 Cerebral Concussion
 Diffuse Axonal Injury (DAI)
 Cerebral Contusion and Laceration
Theory  Intracranial Hematoma
 Extradural/Epidural Hematoma(EDH)
 Subdural Hematoma(SDH)
 Subarachnoid Hematoma(SAH)
 Intracerebral Hematoma(ICH)
 Diffuse Injury to the Brain
 Spinal Cord
 Neck
 Vertebral Column
 Chest & Lungs
Theory SDL Heart, Abdomen, Kidneys, Bones and Joints
Practical NIL
10 Thermal Injuries
 Cold & Heat Injury
 Heat Hyperpyrexia or Heat Stroke
 Burns
 Postmortem Examination
Theory  Medico-legal Questions
 Scalds
 Electrical Injuries(Electrocution)
 Lightning Stroke
Theory SDL  Judicial Electrocution
Practical  Autopsy demonstration
Page 50 of 94
11 Transportation Injuries
 Pedestrian Injuries
 Injuries Sustained by Vehicle Occupants
 Role of Seat Belts and Air Bags
Theory  Motorcycle and Cycle Injuries
 Postmortem Examination
 Alcohol, Drugs and Trauma
Theory SDL  Railway Injuries
Practical  Autopsy demonstration

12 Explosion Injuries and Fall from Height

 Explosion Injuries
 Mechanism of Action
Theory  Classification of Injuries
 Medico-legal Aspects
 Injury Patterns
Theory SDL  Fall from Height
Practical  Autopsy demonstration

13 . Medico-legal Aspects of Injuries

 Simple Hurt/Injury
 Grievous Hurt/Injury
THEORY  Punishments
 Cause of Death from Wounds
 Medico-legal Questions
 Injury Report
Theory SDL NIL
Practical NIL

14 Decompression, Radiation and Altitude Sickness

 Decompression Sickness
Theory  Autopsy in Decompression Sickness
 Altitude Illness
Theory SDL  Ionizing Radiation Reactions
Practical NIL

15 Starvation Deaths
 Mode of Starvation
Theory  Pathophysiology
 Signs and Symptoms
 Postmortem Findings
 Medico legal questions
Theory SDL NIL
Practical NIL

Page 51 of 94
15 Asphyxia
 Pathophysiology of Asphyxia
Theory  Etiology of Asphyxia
 Clinical Effects of Asphyxia
 Hanging
 Autopsy of Neck (Asphyxial Deaths)
 Postmortem Findings in Hanging
 Medico-legal Questions
 Lynching
 Judicial Hanging
 Strangulation
 Ligature Strangulation
 Postmortem Examination
 Medico-legal Questions
 Throttling or Manual Strangulation
 Postmortem Examination
 Medico-legal Questions
 Hyoid Bone Fractures
 Suffocation
 Café-coronary
 Drowning
 Postmortem Examination
 Medico-legal Questions
 Sexual Asphyxia (Autoerotic Asphyxia/ Hypoxyphilia, Asphyxiophilia)
Theory SDL  Hyperventilation Deaths
Practical  Autopsy demonstration

17 Virginity, Pregnancy and Delivery

 Normal Female Anatomy (in Virgins)
Theory  Medico-legal Aspects
 Presumptive Signs/Symptoms
 Probable Signs of Pregnancy
 Positive/Conclusive Signs of Pregnancy
 Pseudocyesis (Spurious/False/Phantom Pregnancy)
 Legitimacy and Paternity
 Signs and Symptoms of Recent Delivery in Living
 Signs of Remote Delivery in Living
 Medico-legal Aspects of Pregnancy and D elivery
 Nullity of Marriage and Divorce
Theory SDL  Superfecundation
 Superfetation
Practical  Certification of Recent delivery

18 Abortion
 Classification of Abortion
Theory  Criminal Abortion
 Complications of Criminal Abortion
 Duties of a Doctor in Suspected Criminal Abortion
 Examination of a Woman with Alleged History of Abortion
 Postmortem Examination
 Trauma and Abortion
Theory SDL  Trauma and Abortion
Practical NIL
Page 52 of 94
19 Infanticide and Child Abuse
 Postmortem Examination of Infants
Theory  Age of Fetus
 Rule of Hasse
 Demonstration of Centres of Ossification
 Features of Dead-Born Fetus
 Signs of Live Birth
 Postmortem Examination
 Infant Death
 Battered Baby Syndrome(Caffey /Maltreatment Syndrome)
Theory SDL  Sudden Infant Death Syndrome (SIDS, Cot Death or Crib Death)
Practical  Examination of Foetus
20 Impotence and Sterility
 Causes of Impotence and Sterility in Males
Theory  Causes of Impotence and Sterility in Female
Examination of a Person in an Alleged Case of
 Impotence and Sterility
 Sterilization & Artificial Insemination(AI)
Theory SDL  Surrogate Mother
Practical  Determination of Potency
21 Sexual Jurisprudence
Natural Sexual Offences
Theory  Rape
 Duties of a Doctor in case of an Alleged Victim of Rape
 Examination of the Rape Victim
 Examination
 Corroborative Signs of Rape
 Rape on Deflorate/Sexually Active Woman
 Rape on Children
 Medico-legal Questions
 Rape Trauma Syndrome
 Examination of Rape Accused
Unnatural Sexual Offences
 Sodomy
 Examination of Passive Agent of Sodomy
 Opinion
 Examination of Active Agent of Sodomy
 Tribadism/Lesbianism
 Bestiality (Zoophilia)
 Buccal Coitus
Sexual Perversions/Deviations
 Sadism (Algolagnia)
 Masochism (Passive Algolagnia)
 Transvestic Fetishism (Eonism)
 Voyeurism(Scoptophilia)
 Exhibitionism
 Fetishism
 Frotteurism (Toucherism)
 Pedophilia
 Masturbation (Onanism) & Indecent Assault
Theory SDL  Incest & Adultery
Practical  Examination of Accused & Examination of Victim
Page 53 of 94
21 Forensic science
 Forensic Science Laboratory
Theory  Forensic Science Organization and its sections
Theory SDL  Locard’s Principle
Practical  Forensic Serology & Hair and Fibers

22 Analytical Forensic Bloodstain Analysis

 Bloodstain Pattern Analysis
Theory  Presumptive Tests for Blood
 Confirmatory Tests for Blood
 Species Identification
 Genetic Markers in Blood
 Medico-legal Application of Blood(Groups)
Seminal Stain and Other Biological Samples
 Purpose of Seminal Identification
 Examination of Seminal Stains
 Confirmatory Tests
 Identification of Species Origin
 Individualization of Seminal Stains
 Identification of Biological Samples and Body Fluids
DNA Fingerprinting
 RFLP & PCR
 Specimen Selection and Preservation
 Uses of DNA Fingerprinting
 Limitations of DNA Testing
Newer Techniques and Recent Advances
 Polygraph
 Brain Fingerprinting (Brain Mapping)
 Narco-Analysis
Theory SDL  Species Identification, Genetic Markers in Blood
 Identification of Biological Samples and Body Fluids
 Limitations of DNA Testing
Practical NIL
23 Forensic Psychiatry
 Delusion
Theory  Hallucination
 Illusion
 Impulse
 Obsession
 Lucid Interval
 Role of Forensic Psychiatrist
 Psychiatric Assessment
 Classification of Mental and Behavioral Disorders
 Organic Mental Disorders
 Schizophrenia
 Mood (Affective)Disorders
 Neurotic and Somatoform Disorders
 Behavioral Syndromes
 Mental Disorder and Responsibility
 The Mental Health Act,1987
Theory SDL  Mental Retardation
Practical NIL

Page 54 of 94
24 General Toxicology
 Medico-legal Aspects of Poisons
Theory  Classification of Poisons
 Factors Modifying the Action of Poisons
 Diagnosis of Poisoning in Living
 Diagnosis of Poisoning in Dead
 Failure to Detect Poison
 Management of Poisoning Cases
 Removal of Unabsorbed Poison
 Administration of Antidotes
 Elimination of Poison by Excretion
Samples Preserved for Toxicological Analysis
Theory SDL  Duties of a Doctor in a Case of Suspected Poisoning
Practical  Doctors, Poisoning and Law
 Preservation of Viscera In Case of Suspected Poisoning

25 Corrosive Poisons
 Mineral Acids
Theory  Vitriol age (Vitriol Throwing)
 Oxalic Acid (Acid of Sugar)
 Carbolic Acid(Phenol)
 Strong Alkalis (Caustic Alkalis)
Theory SDL NIL
Practical NIL
26 Inorganic Metallic Irritants
Arsenic
Theory  Signs and Symptoms (Acute Poisoning)
 Treatment
 Postmortem Findings
 Chronic Arsenic Poisoning
 Postmortem Imbibition of Arsenic
Mercury
 Signs and Symptoms (Acute Poisoning)
 Treatment
 Postmortem Findings
 Chronic Mercury Poisoning (Hydrargyrism)
Lead
 Chronic Lead Poisoning (Plumbism/Saturnism)
 Signs and Symptoms
 Treatment
 Postmortem Findings
 Postmortem Findings
 Chronic Copper Poisoning
Copper
 Signs and Symptoms (Acute Poisoning)
 Treatment
Thallium
 Signs and Symptoms
 Treatment
 Postmortem Findings

Page 55 of 94
 Non-metallic and Mechanical Irritants
 Phosphorus
 Chronic Phosphorus Poisoning
 Mechanical Irritants
Theory SDL Other Inorganic Metallic Irritants
 Cadmium, Barium, Zinc, Metal Fume Fever (MFF), Methemoglobinemia
Inducing Agents
Practical  Toxicology Spotters

27 Organic Irritants—
Vegetable
Theory  Ricinus Communis(Castor)
 Croton Tiglium (Jamalgota)
 Abrus Precatorius (Rati, Gunchi, Jequirity)
 Suis
 Semecarpus Anacardium
 Capsicum Annum
 Calotropis (‘RubberBush’)
 Ergot
Animal
 Snakes
 Signs and Symptoms of Ophitoxemia
 Management
 Postmortem Findings
 Medico-legal Aspects
 Cantharides (Spanish Fly)
 Scorpions
Theory SDL  Bees and Wasps
Practical  Spotters

28 Somniferous Poisons (Narcotic Poisons)

Theory  Opium
 Signs and Symptoms
 Treatment
 Postmortem Findings
 Body Packers
 Chasing the Dragon
 Chronic Morphine Poisoning (Morphinism)
 Fentanyl
Theory SDL NIL
Practical NIL

Page 56 of 94
29 Inebriants—Alcohol
Theory  Signs and Symptoms (Acute Poisoning)
 Treatment
 Postmortem Findings
 Medico-legal Aspects
 Chronic Alcoholism (Systemic Effects)
 Delirium Tremens
 Alcoholic Hallucinosis
 Wernicke's Encephalopathy
 Korsakoff's Psychosis
 Drunkenness
 Diagnosing a Case of Drunkenness
 Laboratory Investigations
 Collection of Samples in Living
 Methyl Alcohol(Methanol)
Theory SDL  Isopropyl Alcohol, Ethylene Glycol
Practical  Examination of A Case of Drunkenness

30 Barbiturates
Theory  Signs and Symptoms
 Management
 Treatment
 Postmortem Findings
Theory SDL  Barbiturate Automatism(Self-poisoning)
Practical NIL
31 Deliriants – Dhatura /Datura
Theory  Dhatura /Datura
 Signs and Symptoms
 Treatment
 Postmortem Findings
Cannabis
 Signs and Symptoms
 Treatment
Cocaine
 Signs and Symptoms
 Treatment
 Cocainism (Cocainomania /Cocainophagia)
Theory SDL  Run-amok
 Magnan's Syndrome/Cocaine Bugs
Practical NIL

32 Spinal and Peripheral Nerve Poisons

 Strychnos Nux-vomica(Kuchila)
Theory
 Curare
Theory SDL  Conium Maculatum (Hemlock)
Practical  Nil

Page 57 of 94
33 Cardiac Poisons

Theory  Aconite (Monk's Hood, Mitha Zaher,Bish)

 Nicotiana Tabacum (Tobacco)
 Digitalis Purpurea (Foxglove)
 Nerium Odorum (White Oleander, Kaner)
 Cerbera Thevetia (Yellow Oleander, Pila Kaner)
Theory SDL  Quinine
Practical NIL

34 Hydrocyanic Acid
Theory  Signs and Symptoms
 Treatment
 Postmortem Findings
 Judicial Execution
Theory SDL NIL
Practical NIL

35 Asphyxiants
Theory  Carbon Monoxide(CO)
 Carbon Dioxide(CO2)
 Hydrogen Sulphide (H2S)
Theory SDL  Nil
Practical  Nil
36 War Gases and Biological Weapons
Theory  War Gases
 Types of Chemical Warfare Agents(CWAs)
 Biological Weapons
 Types of Biological Warfare Agents
Theory SDL NIL
Practical NIL

37 Agricultural Poisons
Theory  Organophosphorus Compounds(OPCs)
 Signs and Symptoms
 Treatment
 Postmortem Findings
 Endrin
 Naphthalene
 Paraquat
 Pyrethrins and Pyrethroids
Theory SDL  Pyrethrins and Pyrethroids
Practical NIL

38 Alphos (Aluminum Phosphide)

Theory  Signs and Symptoms
 Treatment
 Postmortem Findings
Theory SDL NIL
Practical NIL

Page 58 of 94
39 Medicinal Poisons
 Paracetamol(Acetaminophen)
 Iron
 Antipsychotic Drugs(Tranquillizers)
 Antihistaminics
Theory
 Tricyclic Antidepressants(TCAs)
 Benzodiazepines
 Acetylsalicylic Acid(Aspirin)
 Chloral Hydrate
Theory SDL  Acetylsalicylic Acid (Aspirin), Chloral Hydrate
Practical NIL

40 Drug Dependence
Theory  Patterns of Drug Use Disorders
 DSM-IV Criteria for Diagnosis of Substance Dependence
 Psychoactive Substances
 Complications of Drug Abuse
 Postmortem Findings
Theory SDL NIL
Practical NIL

41 Kerosene Oil Poisoning

Theory  Signs and Symptoms
 Treatment
 Postmortem Findings
Theory SDL NIL
Practical NIL

42 Food Poisoning
Theory  Bacterial Food Poisoning
 Botulism (Allantiasis)
 Lathyrus Sativus ('KesariDhal')
Theory SDL  Food poisoning by Mushrooms, Argemone Mexicana (Prickly Poppy)
Practical NIL

43 Anesthetic Deaths
Theory  Death during Administration of Anesthesia
 Deaths Directly Related to Administration of an Anesthetic
 Postmortem Examination
Theory SDL NIL
Practical NIL

44 Postmortem Artifacts
Theory  Artifacts due to Postmortem Changes
 Third Party Artifacts
 Environmental Artifacts
 Other Artifacts
Theory SDL NIL
Practical NIL

Page 59 of 94
45 Torture and Custodial Deaths
Theory  Types of Torture
 Medical Practitioner and Torture
 Custodial Deaths
Theory SDL NIL
Practical NIL

46 Medico-legal Aspects of HIV

Theory  HIV Testing Policy
 Health Care Workers and HIV Infection
 Partner Notification
 Clinical Trials and HIV
Theory SDL  Blood Donation and HIV
Practical NIL

47 Mass Disaster and Investigation

Theory Mass Disaster and Investigation
Theory SDL NIL
Practical NIL

48 Legal and Ethical issues in Biomedical Research

Theory  Legal and Ethical issues in Biomedical Research
Theory SDL  ICMR regulation
 Procedure adopted
 Rules and regulations
 Informed consent
Practical NIL

Page 60 of 94
 PREVENTIVE AND SOCIAL MEDICINE
1 NUTRITION
 Macronutrient& Micronutrients, trace elements
 Balanced diet, dietary goals and RDA
Theory  Nutritional assessment
 Nutritional deficiency, public health problem
 Food adulteration, fortification and standards
Theory SDL  Public health acts related to food quality
 Principles of Nutrition& Diet planning
Practical  Nutrition & Diet planning- case scenarios
 Nutrition spotters demonstration

2 Sociology
Theory  Introduction to Medical Sociology
 Behaviour, Culture, Role of family in health and disease
 Social security, psychology and social organizations
Theory SDL  Student seminar based on case scenarios – ( Role of Behaviour, Role of Culture,
Social problems, Social class, Role of family in health and disease)
 Group Discussions - Social security , Social Organizations, Intelligence,
Psychology , Motivation, Art of Interviewing
Practical  Social Problems Related to Geriatric Care

3 REPRODUCTIVE AND CHILD HEALTH

 Introduction to RCH
 Maternal health
 New Born Care
Theory
 Child Health ( Growth & Development ,ICDS)
 Indicators of MCH Care
 Programmes ( School Health Programme)
 Juvenile Delinquency
 Child abuse, Street Children , Refugee and Displaced Children, Child Labour, Child
Trafficking
 Maternal and child tracking system
Theory SDL  Every New Born Action Plan
 India New Born Action Plan
 Mission Indradhanush
 Elimination of maternal and neonatal tetanus
 Global strategic measles and rubella Plan
 Immunisation
 Immunisation spotters
 Family welfare measures
 Family welfare spotters
Practical  Integrated management of neonatal and childhood illness
 Exercises on IMNCI
 Adolescent health
 Spotters on IMNCI
 Growth monitoring

Page 61 of 94
4 Biostatistics
 Introduction to biostatistics, Types of data
Theory
 Measures of central tendency and dispersion, concept of statistical significance
 Sources of health information
Theory SDL  Sampling- revision
 Probability
 Measures of central tendency/Location
Practical  Measures of dispersion(Range, Standard deviation, Standard error, Co-
efficient of variation)

5 Demography
 Introduction to demography and vital statistics, uses and demographic transition
Theory
 Fertility and Mortality indicators
 Family planning measures-Revision
Theory SDL
 Population stabilisation
 Fertility indicators, dependency ratios
Practical
 Mortality indicators
6 Epidemiology
 Introduction to Epidemiology &Study Designs
 Basic Measurements in Epidemiology
 Descriptive Studies
 Case control Studies
Theory  Cohort Studies
 Interventional Studies
 Bias and confounding
 Association& Causation of Disease
 Screening for Diseases- Types of screening, definitions
 Measurements in health and disease
Theory SDL  Standardization
 International death certificate
 Exercises on Morbidity indicators
 Exercises on case control study
 Exercises on Cohort study
Practical  Investigation of outbreak
 Exercise on Outbreak investigation
 Exercises on Screening –Sensitivity, Positive Predictive value, Negative Predictive
value

7 ENVIRONMENT
Theory  ENVIRONMENT
 Water – Sources, Water related diseases
 Air Pollution – Prevention and control
Theory SDL
 Noise Pollution –Effects, Prevention and control
 Radiation
 Sewage treatment methods - Visit to Sewage treatment plant
 Water quality standards - Visit to Water works, Muthirapalayam
 Water purification methods - Horrock’s apparatus and Choloroscope
Practical demonstration
Block posting  Housing – Housing assessment during Family health advisory posting
 Light and ventilation – Housing assessment during Family health advisory posting
 Medical Entomology
Page 62 of 94
8 COMUNICABLE DISEASES
 Infectious disease epidemiology, Dynamics of disease control
 Principles of Disease prevention and control
 Acute Respiratory Illness
 Tuberculosis
 Malaria
Theory
 Dengue, Filariasis & JE
 Acute Diarrheal Diseases
 Poliomyelitis
 Rabies
 HIV/AIDS
 Control of Infectious diseases - Achievements in public health
 Small Pox, ChickenPox, Measles
 Diphtheria, Pertussis Tetanus
 Emerging and re-emerging diseases- Influenza, ebola, zika
 Plague ,leptospirosis
Theory SDL
 Leishmaiasis
 Syndromic approach for STD’s
 Typhoid, cholera
 Rickettsial infections
 RF/ RHD
 Exercises on Communicable diseases control –Malaria
Practical  Exercises on Communicable diseases control – Filariasis, others
 Communicable diseases control –TB

9 NCD Epidemiology
 Introduction to NCD and Mental Health
 Risk factors for NCD
 Diabetes Mellitus
 Cardio-vascular diseases: HTN, IHD, Stroke
Theory
 Cancers
 Blindness
 Road Traffic Injuries
 Health Promotion 2,3,4,5,6,7,8: SCL . 1,9,10 : Lecture-Discussion
Theory SDL
 Practical session on “Prevention and Control of Injuries” – 2sessions
Practical  WHO-ISH carting and risk calculation as a part of FHAP
 IDRS calculation as a part of FHAP
(Family Health  Behavioural change communication as a part of FHAP
Advisory  GHQ assessment as a part of FHAP
programme)  Assessment of ADL as a part of FHAP
 Health Communication with the elderly as a part of FHAP
 Case scenario discussion – 1, 2- 7: Skill based learning and evaluation

Page 63 of 94
 GENERAL MEDICINE
III Semester
Introductory 1 Introduction on Practice of Medicine (Art of Medicine, Doctor-Patient
classes relationship, Responsibilities of a doctor and Evidence Based Medicine)
2 Negligence, Patient autonomy, conflict of interest,
Confidentiality, Informed consent, Euthanasia
3 Genetics – Basic (modes of inheritance, pedigree, clinical application
and counseling
4 Nutritional assessment and requirements
General symptoms 5 Pain - Pathophysiology, Clinical types, Assessment, Management
6 Weight Loss and Weight Gain
Infectious 7 Approach to infectious diseases - diagnostic and therapeutic
diseases - principles; Immune defence mechanisms
introduction
8 Alterations in Temperature, Fever patterns
9 Alteration in Pulse and Blood Pressure
Symptomatology; 10 Dyspnea, Chest Pain, Palpitation
Infectious diseases - 11 Cough, Haemoptysis, Cyanosis, Clubbing
RS,CVS 12 Pneumonia
13 Influenza
IV Semester
14 Anorexia, Nausea, Vomiting, Abdominal Pain, dysphagia
15 Diarrhoea, Constipation, G.I. Bleeding
16 Jaundice, Hepatomegaly
17 Acute infectious diarrhoeal diseases - overview; Food
poisoning and toxin mediated diarrhoea (Cholera); Traveller's
GIT
diarrhea
18 Shigellosis; EIEC; Amoebiasis; Giardiasis
19 Enteric fever and Salmonella infections
20 Worm infestations (Hookworm, roundworm, tapeworm, pinworm,
Strongyloidiasis)
21 Urinary tract symptoms (Oliguria, anuria, dysuria, pyuria, hematuria,
polyuria, nocturia, chyluria and enuresis)
Renal, urinary tract 22 Ascites, Edema, Anasarca
23 Urinary tract infections - etio-pathogenesis, types, clinical features,
diagnosis and treatment
Hematology 24 Pallor, Bleeding, Thrombosis, Splenomegaly,
Lymphadenopathy
25 Headache (migraine), vertigo and dizziness
26 Seizures, Syncope
27 Motor and sensory disturbances
Central nervous system
28 Disturbances of consciousness, (brain death and organ donation)
29 Rabies and other encephalitides (JE, HSV)
30 Bacterial meningitis
Articular symptoms 31 Arthralgias, arthritis and myalgias; Chikungunya
32 Malaria
33 Haemorrhagic fevers (Dengue); Leptospirosis; Rickettsial infection
34 Bacteremia, sepsis, SIRS, MODS, Septic shock
Not classifiable into a
35 Brucellosis, Plague, Anthrax
particular system: ID
36 Clostridial infections - Tetanus, gas gangrene, botulinum, CDAD
37 Nosocomial infections
38 Herpes zoster, EBV, CMV, HHV-8
Page 64 of 94
 Not classifiable into a 39 HIV - Definitions, transmission, epidemiology, clinical
particular system: ID manifestations, diagnosis
40 HIV and opportunistic infections
41 Management of HIV/ AIDS
V SEMESTER
Not classifiable into a 42 Common fungal infections (Candida, Aspergillus, Mucor, Cryptococcus)
particular system: ID 43 Filariasis; Leishmaniasis
44 Hydatid disease; Toxoplasmosis
45 Stings and bites (Snake bite, scorpion sting and others)
46 Poisoning - general principles; OP poisoning, Carbamate poisoning,
Not classifiable into a Organochlorine poisoning
particular system: 47 Plant poisons (Yellow oleander, abrus, cleistanthus collinus
Envenoma and datura)
48 Yellow phosphorus, Paraquat, Corrosives, Prescription drug
poisoning
Not classifiable into a 49 Heat related disorders; Radiation related disorders
particular system:
50 Drowning and electrical injuries
Environment
51 Introduction; Presenting problems in renal diseases (Edema,
hypertension, renal failure, hematuria, proteinuria)
52 Glomerular disorders – overview; Nephritic syndrome – etiology,
types, pathology, clinical features, diagnosis, treatment and
Nephrology: Few classes complications.
53 Nephrotic syndrome – causes, clinical features, diagnosis,
complications and treatment.
54 Tubular disorders, Ischemic Kidney Disease, Drugs and
Toxin induced nephropathy.

Page 65 of 94
 GENERAL SURGERY
Clinical presentation Theory Theory SDL Practical
1. Nervous system Trauma Assessment

2. Endocrine system
a. Approach to Goitre Thyroid function Clinical examination of
1. Thyroid
b. Thyroid dysfunction test Interpretation Thyroid
a. Hypocalcemia and
2. Parathyroid Investigations
Hypercalcemia
3. Breast a. Approach to breast
complaints Clinical examination
b. Gynecomastia of Breast
c. Investigations
4. Adrenalmass a. Presentation

a. Shock
b. Approach to arterial Assessment of shock
disease Clinical examination of
c. Approach to venous Arterialdisease
3. Cardiovascular
diseases Clinical examination of
system Assessment
d. Approach to Lymphatic venousdisease
diseases Clinical examination of
e. Approach to cardiac lymphatic diseases
trauma
4. Respiratory system Approach to Chest trauma
a. Abdomen Pain
b. Abdomen mass
c. Weight changes
d. Upper GI complaints
a. Oral lesions
b. Dysphagia
c. Vomiting
d. Bleeding
e. Abdomen
Clinical examination of
distension a. Gastric
Acute abdomen
f. Upper abdomen pain function tests
Clinical examination of
5. Gastrointestinal e. Lower GI complaints b. Liver
Chronic abdomen
system a. Abdomen function test
complaints
distension c. Pancreatic
Clinical examination of
b. Abdomen pain function test
jaundice
c. Vomiting
d. Constipation
e. Diarhoea
f. Fecalincontinence
g. Anorectal pain
f. Hepatobiliary andPortal
a. Hepatosplenomegaly
b. Jaundice
c. Liver functiontest

Page 66 of 94
 a. Upper urinary tract
Symptomatology
a. Hematuria/pyuria
b. Dysuria
c. Flankpain
d. Abdomenmass
b. Lower urinary tract
6. Renal and Urinary symptomatology
system a. Dysuria/Pain
b.Hematuria/pyuria
c. Urinary
incontinence
d.Urinary retention
e. Ostructive and irrative
symptoms
f. Prostatomegaly
Clinical examination of
7. Male reproductive a. Penile lesions Penile lesions
system b. Scrotum complaints Clinical examination
of Scrotal mass
Clinical examination of
a. Soft tissue swelling
8. Musculoskeletal Swelling
b. Limb swelling
system Examination of Foot
c. Foot Infection
Infections
Clinical examination of
9. Hematologic system Lymph node swelling
lymph node
a. Swellings
b. Ulcers
Clinical examination of
10. Dermatologic system c. Pigmentation
Skin lesions
abnormalities/ Colour
changes/ skin changes
Wound healing Infections
Fluid balance Nutrition
11. General surgery Preoperative care
Post-operative care
Blood transfusion

Page 67 of 94
 OBSTETRICS & GYNECOLOGY
IV and V Semesters
1 Introduction
Definition of Obstetrics,
Theory
Epidemiology of Obstetrics,
Theory SDL Importance of obstetrics
2 Maternal and perinatal morbidity and mortality
Causes
Theory Prevalence
Rates
Theory SDL Maternal mortality rate in India
3 Fundamentals of reproduction
Fertilization,
Theory
Implantation
Theory SDL Decidua
4 Embryogenesis
Theory Stages of embryo development
Theory SDL Pictorial representation of stages
5 Factors influencing normal development
Drugs
Theory Radiation
Infections
Theory SDL Environmental influences
6 Development of fetus
Fetal physiology
Theory
Fetal circulation and changes at birth
Theory SDL Abnormalities of fetal circulation
7 Development of placenta
Development
Theory
Placenta circulation, function,ageing
Theory SDL Umbilical cord
8 Tutorial
9 Endocrinology of pregnancy
Placental endocrinology
Theory
Protein hormones
Theory SDL Importance of various hormones
10 Endocrinology of pregnancy
Steroid hormones
Theory
Changes of endocrine glands
Theory SDL Maintenance of lactation
11 Symptoms of pregnancy
Trimesters-1st,2nd,3rd
Theory Chronological appearance of symptoms of pregnancy Differential diagnosis
Estimation of gestational age and prediction of expected date of delivery
Theory SDL Different methods of estimation of gestational age

Page 68 of 94
12 Signs of pregnancy
Trimesters-1st,2nd,3rd
Theory Chronological appearance of signs of pregnancy Differential diagnosis
Estimation of fetal weight
Theory SDL Signs of previous childbirth
13 Tutorial
14 Physiological and Emotional changes during pregnancy
Genital organs
Breasts
Theory
Cutaneous changes
Hematologic changes
Theory SDL Importance of changes in pregnancy
15 Physiological and Emotional changes during pregnancy
Body and water metabolism
Cardiovascular changes
Theory
Metabolic changes
Systemic changes
Theory SDL Weight gain
16 Diagnosis of pregnancy ( laboratory & ultrasound )
Urine/Blood -pregnancy Test
Theory
Ultrasound - 1st,2nd,3rd Trimesters
Theory SDL False positive/negative urine pregnancy tests
17 Theory test
18 Antenatal Care
Procedure at first and subsequent visits
Theory
Methods of obstetrical Examination
Theory SDL Values of antenatal care
19 Antenatal care 2
Minor ailments in pregnancy Antenatal advice
Theory
Preconceptional care
Theory SDL Folic acid supplementation
20 Antenatal care 3
Clinical evaluation of fetal well being
Theory Special investigations
Pregnancy assessment
Theory SDL Antenatal counselling
21 Tutorial
22 Nutrition in pregnancy
Calories
Theory Daily requirement of Carbohydrates, Protein, Fats
Micronutrients
Theory SDL Sources of dietary iron
23 Anatomy of normal labour
Causes of onset of labour
Theory
Contractile system of myometrium
Theory SDL Pictorial representation of anatomical changes
Page 69 of 94
24 Physiology of normal labour
Stages
Theory Events in labour
Mechanism of normal labour
Theory SDL Labour video
25 Partogram
Concept Uses
Theory Components
Advantages
Theory SDL WHO partogram
26 Normal puerperium
Involution of the uterus
Lochia
Theory
General physiologic changes
lactation
Theory SDL Menstruation and ovulation after delivery
27 Tutorial
28 Family welfare programme
Family planning infrastructure/organization
Theory Evolution of the programme
Trends and Indian statistics
Theory SDL Population policy
29 Fertility control
Contraception
Theory
Introduction to various methods
Theory SDL Reasons for fertility control
30 Demography
World population statistics National population policy
Theory
Demographic changes
Theory SDL Indian statistics
31 Population dynamics.
Terminology
Theory
Population growth
Theory SDL National rural health mission
32 Theory test

Page 70 of 94
 PEDIATRICS
1. Introduction to Pediatrics
1.1 Definition of Pediatrics, differences between child and adult
1.2 Symptoms based approach to pediatrics (common symptoms related to CVS, RS,GIT)
1.3 Symptoms based approach to pediatrics (common symptoms related to renal, CNS,
musculoskeletal systems)
1.4 Cardinal signs relevant to pediatrics (Pallor, Icterus, Cyanosis, Clubbing,
Lymphadenopathy and Edema)
1.5 Vital signs: normative data in children
1.6 Recognition of a sick child
Integrated management of neonatal and childhood illness
2 Introduction to Neonatology
2.1 Definition of Neonatology and normal findings in a newborn
2.2 Gestational and birth weight based classification of neonates
2.3 Temperature regulation and feeding of neonates
SDL. Community based interventions for the prevention of low birth weight babies
3 Growth and development
3.1 Principles of growth and development and factors affecting growth and development
3.2 Key developmental milestones (gross motor, fine motor, cognitive, social and language)
3.3 Developmental delay- risk factors and assessment
3.4 Assessment of growth
3.5 Disorders of growth
3.6 Adolescent growth and development
SDL Growth charts and their utilities
4 Fluid and Electrolyte Homeostasis
4.1 Principles of fluid therapy in children
4.2 Regulation of acid base balance in children and disorders related to them
4.3 common electrolyte abnormalities in children and their management
4.4 Fluid management in special situations
SDL Composition of different types of intravenous fluid preparation and their utility
5 Nutrition
5.1 Basics of nutrition and nutritional requirements of children 5.2Principles of breast feeding
and advantages
5.3 Impediments to breast feeding and their management
5.4 principles of complementary feeding
5.5 Fat soluble vitamins: Vitamin A and D- sources, deficiency features, toxicity and
management
5.6 Fat soluble vitamins: Vitamin E and K- sources, deficiency features, toxicity and
management
5.6 Water soluble vitamins: Thiamine, Riboflavin, Niacin, Pantothenic acid- source,
deficiency features and management
5.7 Water soluble vitamins: Pyridoxine, Biotin, Folic acid, cyanacobalamin, vitamin C- source,
deficiency features and management
5.8 Minerals and trace element deficiencies in children
5.9 Protein Energy Malnutrition – Definition, classification, clinical features, management
strategies and prevention
SDL Age independent anthropometric measures for detecting malnutrition in the community

Page 71 of 94
 TOTAL TEACHING HOURS

Subject Discipline Theory Practicals Total

1 Microbiology 131 66 197
2 Pathology 131 65 196
3 Pharmacology 131 90 221
4 Forensic Medicine 136 84 220

WEEKLY TIMETABLES FOR MBBS PHASE II

III SEMESTER (REGULAR) –JULY END-AUGUST TO DECEMBER

10.00- 1.00
Days 8.00-9.00 AM 9.00-10.00 AM 2.00-3.00PM 3.00-4.30 PM
PM

Pathology
Forensic
Pharmacology Clinics/ Pathology - Practicals A,B batch
Monday Medicine - 1
-1 (Theory) Skills lab 1 (Theory) Microbiology
(Theory)
Practicals C, D batch

Medicine Microbiology - 1 Clinics/

Tuesday Community Medicine
(Theory) (Theory) Skills lab

Forensic Microbiology Pathology

Pathology – 2 Clinics/ Practicals C, D batch
Wednesday Medicine -2 –2
(Theory) Skills lab Microbiology
(Theory) (Theory) Practicals A,B batch

Time :- 02.00 PM to 3.15 PM

Pathology
Practicals A,B batch
Forensic Medicine
Practicals C, D batch
Pathology -3 Community Clinics/
Thursday Time :- 3.15 PM to 04.30 PM
(Theory) Medicine Skills lab
Pathology
Practicals C,D batch
Forensic Medicine
Practicals A, B batch

Pharmacology -2 Clinics/
Friday Surgery (Theory) Pharmacology
(Theory) Skills lab

Microbiology -3 Pharmacology – 3 Clinics/

Saturday
(Theory) (Theory) Skills lab

Page 72 of 94
 IV SEMESTER (REGULAR) – DECEMBER TO MAY

10.00- 1.00
Days 8.00-9.00 AM 9.00-10.00 AM 2.00-3.00PM 3.00-4.30 PM
PM

Pathology
Pharmacology Pathology -1 Clinics/ Microbiology-1 Practicals A,B batch
Monday
-1 (Theory) (Theory) Skills lab (Theory) Microbiology
Practicals C, D batch

Forensic Clinics/ Pathology – 2 Forensic Medicine -

Tuesday Paediatrics Medicine - 1
(Theory) Skills lab (Theory) Practicals

Pathology
Pharmacology
Clinics/ Pathology – 3 Practical C,D batch
Wednesday Obst & Gynae –2
Skills lab (theory) Microbiology
(theory)
Practical A, B batch

Medicine Community Clinics/ Microbiology 2 Community

Thursday
(Theory) Medicine Skills lab (theory) Medicine
Pharmacology Clinics/
Friday Medicine Pharmacology
-3 (Theory) Skills lab
Surgery Microbiology – Clinics/
Saturday
(Theory) 3 (Theory) Skills lab

V SEMESTER (REGULAR) - MAY - DECEMBER

10.00- 1.00
Days 8.00-9.00 AM 9.00-10.00 AM 2.00-3.00PM 3.00-4.30 PM
PM
Microbiology - Clinics/
Monday Surgery Pharmacology
1(Theory) Skills lab
Pathology
Forensic Med Clinics/ Microbiology Practical A,B batch
Tuesday Paediatrics
– 1(Theory) Skills lab 2 (theory) Microbiology
Practical C, D batch

Pharmacology Clinics/
Wednesday Obst & Gynae Forensic Medicine
– 1(Theory) Skills lab

Pharmacology Community Clinics/ Microbiology Community

Thursday
– 2(Theory) Medicine Skills lab 3(theory) Medicine

Pathology
Pharmacology – Clinics/ Pathology Practicals C,D batch
Friday Medicine
3 (Theory) Skills lab 1(theory) Microbiology
Practicals A, B batch

Pathology – Clinics/
Saturday Surgery
2(theory) Skills lab
Page 73 of 94
 TIME TABLE FOR CLINCIAL TRAINING OF III, IV & V SEMESTER

CLINICAL POSTINGS OF III SEMESTER

Community
Period Surgery OBGY Medicine
Medicine
1 Month A B D C

1 Month C A B D

1 Month D C A B

1 Month B D C A

CLINICAL POSTINGS OF IV & V SEMESTER

End Batch A Batch B Batch C Batch D

2 Weeks Medicine Surgery Community M Community M
2 Weeks Medicine Surgery Community M Community M
2 Weeks Medicine Surgery OBG Paediatrics
2 Weeks Surgery Medicine OBG Paediatrics
2 Weeks Surgery Medicine OBG Paediatrics
2 Weeks Surgery Medicine OBG Skin
2 Weeks OBG Paediatrics Medicine Surgery
2 Weeks OBG Paediatrics Medicine Surgery
2 Weeks OBG Paediatrics Medicine Surgery
2 Weeks OBG Ortho Surgery Medicine
2 Weeks Skin Ortho Surgery Medicine
2 Weeks Anaesthesiology Skin Surgery Medicine
2 Weeks Community M Community M Anaesthesiology OBG
2 Weeks Community M Community M ID OBG
2 Weeks Paediatrics Anaesthesiology ID OBG
2 Weeks Paediatrics ID Ortho OBG
2 Weeks Paediatrics ID Ortho Anaesthesiology
2 Weeks ID OBG Paediatrics Ortho
2 Weeks ID OBG Paediatrics Ortho
2 Weeks Ortho OBG Paediatrics ID
2 Weeks Ortho OBG Skin ID

Page 74 of 94
III Semester – Clinical Training in the subjects of Medicine, Surgery & OG – content –
first four months of intensive clinical posting in various departments.
1. Communication skills development
2. Bedside Manners
3. History Recording of a patient
4. Physical Examination of a patient
5. Analysis of Symptoms and signs
6. Diagnosis

1. Communication skills development – Tamil Language teaching at bedside

2. Bedside Manners – How to behave in front of a patient, developing rapport with patient, getting
consent for examination, learning empathy and sympathy

3. History Recording of a patient – Name, age, sex, address, occupation, Present illness, past illness,
family pedigree, drug intake,

4. Physical Examination of a patient – Height, weight, BMI, vitals recording (pulse, blood pressure,
temperature and respiratory rate), system examination-inspection, palpation, percussion and
auscultation

5. Analysis of symptoms and signs – to identify the system involved and focus on the examination of
the particular system in an algorithmic manner.

6. Arriving at a diagnosis using not a single physical sign but using multiple physical signs.

7. Learning to use clinical medicine tools – stethoscope, Torch light, tongue depressor, tuning fork,
inch tape, knee hammer, trans illuminator, wearing gloves, proctoscopy.

Clinical training in IV & V Semester

1. Clinical case record maintenance

2. Clinical case presentation

3. OSCE

4. Learning about investigations

5. Interpretation of investigations

6. Learning algorithm of investigations for various disorders

7. Learning about various formulae used in clinical medicine

Page 75 of 94
 II - PROFESSIONAL YEAR (Para-Clinical Subjects)
Name of the Subject Evaluation parameter Maximum Passing
Marks minimum
Written (2 Papers) 160 80
Written including oral 180 90
Microbiology Practical 100 50
Internal Assessment (Theory-40; Practical-30) 70 35
Overall (Total) 350 175
Written (2 Papers) 160 80
Written including oral 180 90
Pathology Practical 100 50
Internal Assessment (Theory-40; Practical-30) 70 35
Overall (Total) 350 175
Written (2 Papers) 160 80
Written including oral 180 90
Pharmacology Practical 100 50
Internal Assessment (Theory-40; Practical-30) 70 35
Overall (Total) 350 175
Written (1 Paper) 80 40
Written including oral 100 50
Forensic Medicine Practical 100 50
Internal Assessment (Theory-20; Practical-20) 40 20
Overall (Total) 240 120

Eligibility to appear for examination

Attendance = 75 %
Internal Assessment Marks = 50%

Marks qualifying for pass

50% in Theory
50% in Theory including Viva-Voce
50% in Practical
50% in Internal Assessment
50% in Total Aggregate

Page 76 of 94
 LEARNING RESOURCE MATERIALS
MICROBIOLOGY
RECOMMENDED TEXTBOOKS

1. Jawetz Melnick and Adelberg’s Medical Microbiology, 2016, 27th edition , LANGE Publications
2. Ananthanarayan , Paniker and Arti Kapil’s Textbook of Microbiology, 2013, 9th edition,
University Press
3. Subhash Chandra Parija Textbook of Microbiology and Immunology, 2016, 3rd edition, Elsevier
India
4. Subhash Chandra Parija Textbook of Medical Parasitology, 2013, 4th edition, All India
Publishers New Delhi
5. Sastry Apurba Sankar Essentials of Medical Microbiology, 2016, 1st edition,
JAYPEE BROTHERS Publishers
6. Mandell, Douglas and Bennett’s Principles and Practice of Infectious Disease, vol 1 and
2, 2015, 8th edition, Elsevier

REFERENCE TEXTBOOK
1. Lynne S. Garcia, Diagnostic Medical Parasitology, 2016, 6th edition, Garland Science,
Taylor and Francis Group
2. Peter J. Delves, Seamus J. Martin, Dennis R. Burton, Ivan M. Roitt Essential
Immunology, 2016,13th edition, Wiley- Blackwell publications
3. Jagdish Chander, Textbook of Medical Mycology, 2009, 3rd edition, Mehta publications
4. Kasper, Fauci, Hauser, Longo, Jameson, Loscalzo, Harrison’s Principles of Internal
Medicine, vol 1 and 2, 2015, 19th edition, McGraw Hill Publications
5. N.N Damani, Manual of Infection Control Procedures, 2004, 2nd edition, Cambridge University
Press
6. Peter Lydyard, Michael Cole, John Holton, Will Irving, Nino Porakishvili, Pradhib
Venkatesan, Kate Ward, Case Studies in Infectious Diseases, 2010, 1st edition, Garland
Science, Taylor and Francis Group

Page 77 of 94
 PATHOLOGY

BOOKS:

1. Kumar V, Abbas A, Aster JC. Pathologic basis of disease: South Asia edition. 9 ed.
Haryana: Elsevier; 2014.
2. Kumar V, Abbas A, Aster JC. Robbins Basic Pathology. 9 ed. Philadelphia: Elsevier ;2013.
3. Walter JB, Talbot IC. Walter and Israel General Pathology. 7 ed. Edinburgh; Elsevier ;1963
4. Cross SS. Underwood’s Pathology: A clinical approach. 6 ed. China; Elsevier;2013
5. Singh T. Text and Practical Hematology for MBBS. New Delhi: APC Publications;2010.
6. Chaturvedi U, Singh T. Practical Pathology. 2 ed. New Delhi: Arya Publications;2015.

Online Resources:

1. www.pathologyoutlines.com/

2. http://www.webpathology.com

PHARMACOLOGY
1. Katzung BG, Trevor AJ, Master SB. Basic and clinical pharmacology. 13th ed. New
York: Mc Graw Hill;2015.
2. Bennett PN, Brown MJ, Sharma P. Clinical pharmacology. 11th ed.
Edinburgh: Churchill Livingstone;2012.
3. Trevor AJ, Katzung BG, Knuidering-Hall M. Katzung & Trevor’s Pharmacology
examination and board review. 11thed. New York:McGraw-Hill;2015.
4. Brenner GM, Stevens C. Pharmacology. 4th ed. Edinburgh: ChurchillLivingstone;2013.

5. Neal MJ. Medical Pharmacology at a glance. 8th ed. Oxford:Wiley-Blackwell;2016.

6. Whalen K. Lippincott Illustrated Reviews: Pharmacology. 6th ed. New Delhi: Wolters
Kluwer (India); 2014.
7. Rang HP, Dale MM, Ritter JM, Flower RJ, Henderson G. Rang & Dale’s
Pharmacology. 8th ed. Edinburgh: ChurchillLivingstone;2015.
8. Papadakis MA, Mcphee SJ, Rabow MW. Current medical diagnosis and treatment 2017.
56th edition. New York: McGrawHill;2016.
9. Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J. Harrison’s
Principles of internal medicine. 19th ed. New York: Mc GrawHill;2015.
10. Bhat P, Dretler A, Gdowski M, Ramgopal R, Williams D. The Washington
manual ofmedical therapeurtics. 35thed. New Delhi: Wolters Kluwer (India).2016.

Page 78 of 94
 A. FORENSIC MEDICINE
LIST OF BOOKS
1. Knight’s Forensic Pathology Saukko & Knight 3rd Ed
2. Colour Atlas of Forensic Medicine A. Govindiah 2ndEd
3. The Essentials of Forensic Medicine &Toxicology K.S.Narayan Reddy 33rdEd
4. Textbook of Forensic Medicine &Toxicology V V Pillay 17thEd
5. Review of Forensic Medicine & Toxicology Gautam Biswas 3rdEd
6. Principle of Forensic Medicine & Toxicology Rajesh Bardale 1stEd
7. Textbook of Forensic Medicine &Toxicology Nagesh Kumar Rao 2ndEd
8. Modern Medical Toxicology VV Pillay 4th Ed
9. Textbook of Forensic Medicine &Toxicology KrishnanVij 6th Ed
10. Oral & Practical Examination Questions in ForensicMedicine D.Govindiah 1stEd
11. Practical Forensic Medicine Nagesh KumarRao 3rdEd
12. Textbook of Medical Jurisprudence, Forensic Medicine & Toxicology Parikh 7thEd
13. Modi A textbook of Medical Jurisprudence &Toxicology KKannanetal 25thEd
14. Practical Aspect of Forensic Medicine RK Gorea et al 1stEd
15. Principles of Forensic Medicine including Toxicology Apurba Nandy 3rdEd
16. Lyon’s Medical Jurisprudence and Toxicology Dogra,T.D 11thEd
17. Forensic Medicine & Toxicology: Theory, Oral and Practical Karmakar, R. L 5thEd
18. Forensic Medicine and Toxicology Ignatius, P.C 2ndEd
19. Textbook of Forensic Medicine &Toxicology Anil Agarwal 1stEd

LIST OF JOURNALS
1. Journal of Indian Academy of Forensic Medicine
2. Journal of Indian Society of Toxicology
3. Legal Medicine
4. Journal of Forensic and Legal Medicine
5. American Journal of Forensic Medicine and Pathology
6. Forensic Science International

Page 79 of 94
 ESSENTIAL SKILLS LIST: LAB PROCEDURALSKILLS

MICROBIOLOGY
S. No Practical skill Timing of Assessment
Performance and interpretation of Gram stain of direct
1 Internal assessment and Final exam
and culture smears
Performance and interpretation of Albert stain for
2 Internal assessment
granules of Corynebacterium diphtheria
Performance and interpretation of Kinyoun stain of
3 Internal assessment and Final exam
sputum smears for AFB
Preparation and interpretation of wet mount of stool
4 Internal assessment and Final exam
specimens forova/cysts of parasites
Preparation of thick and thin smears of peripheral blood
5 Formative assessment
for malarial parasites
Collection , transport and storage of samples for
6 Formative assessment
microbiological investigations
Interpretation of culture and AST reports Choice of
7 Internal assessment and final exam
empirical therapy for different clinical syndromes
Interpretation of common serological tests – Widal,
8 VDRL/RPR, Weil-Felix. SAT for brucellosis, ASLO, Internal assessment and final exam
CRP etc
Principles of sterilization and biomedical waste
9 Formative assessment
management
Principles of universal/airborne/contact precautions and
10 Internal assessment
other measures to control HAI

PATHOLOGY
a) Be able to collect, store and transport materials for various pathological tests including
histopathology, cytopathology, hemato pathology, Blood bank and clinical pathology in a proper
manner.
b) Describe accurately and arrive at a logical diagnosis of common macroscopic specimens (gross
appearance) such as cirrhosis, gangrene, tumors etc. Interpret and arrive at a conclusive diagnosis in
the microscopic analysis of common diseases like tuberculosis, carcinoma, acute inflammation etc.
c) Perform with accuracy and reliability various hematological procedures such as Hemoglobin
estimation, Total and differential leucocyte count, peripheral smear staining and reporting.
d) Calculate red cell indices and interpret the significance
e) Perform independently complete examination of urine and detect abnormal findings and interpret
the results
f) Perform independently grouping of blood.
g) Be aware of the procedure for common tests like Bleeding time, Clotting time, ESR, PCV, bone
marrow examination, semen analysis and interpret abnormal findings.
h) Interpret abnormal laboratory (biochemical, hematological and serological) values of common
diseases.
i) Adopt universal precautions for self-protection against HIV and hepatitis

Page 80 of 94
 PHARMACOLOGY
S. No Skill
1 Loading the given amount of drug in the syringe
Administering the drug subcutaneously / intramuscularly /
2
intravenously in the given model
3 Setting up of an intravenous infusion
Prescribing for common medical conditions that will be
4
encountered by a general practitioner
Communicate effectively regarding the correct use, storage
5
and disposal of medicines and devices like metered dose inhaler and spacer

6 Interpreting the results of therapeutic drug monitoring report

7 Critically appraise the drug promotional literature

Page 81 of 94
 FINAL EXIT EXAMINATION – RULES & REGULATIONS

Final exit examinations are to be designed with a view to ascertain whether the candidate has
acquired the necessary knowledge, minimum skills, ethical and professional values with clear concepts of
the fundamentals which are necessary for him/her to function effectively and appropriately as a physician of
first contact. Assessment shall be carried out on an objective basis to the extent possible. Eligibility to
appear for final exit examination for all the subjects include 75% attendance in theory, 75%
attendance in practicals, 50% marks in theory internal assessment and 50% marks in practicals
internal assessment, duly certified by the concerned department HOD/ Faculty In-charge of
examinations from the department.
The candidates who lacks eligible attendance and/ or internal assessment marks will be detained. The
detained candidates in phase II has to improve the attendance and/or internal assessment by attending special
classes/ notified tests within the period of next examination. Those candidates who fulfil the above said
criteria alone will be permitted along with other candidates in the next examinations. Medical leave of
absence of more than one month has to be certified by Medical board of JIPMER. Medical Leave more than
three months, the candidate will be permitted to appear for examination.
Nature of questions will be structured essay, short answer type/objective type and marks for each
part indicated separately.
Practical/clinical examinations will be conducted in the laboratories or hospital wards. The objective
will be to assess proficiency and skill to conduct experiments, interpret data and form logical conclusion.
Clinical cases kept in the examination must be common conditions that the student may encounter as a
physician of first contact in the community. Rare syndromes and disorders are to be discouraged. Emphasis
should be on candidate’s capability in elicit a history demonstrate physical signs write a case record, analyze
the case and develop a management plan.
Viva/oral includes assessment of management approach and handling of emergencies, ethical and
professional values. Candidate’s skill in interpretation of common investigative data, X‐Rays, identification
of specimens, ECG, etc. also is to be assessed.
A student shall not be allowed to graduate later than 09 (nine) years of joining first MBBS
course (Double the duration of the course). The candidate’s name will be struck off from the roll if
he/she did not complete the entire course within the stipulation mentioned (Double the duration of the
course).

Page 82 of 94
Annexure- I – MODEL QUESTION PAPERS

Page 83 of 94
 MICROBIOLOGY
Paper - I
Time: Three Hours Maximum Marks: 80
Each Section to be answered in separate answer book
Illustrate your answers with suitable diagrams
SECTION A (Marks : 40)
(General Microbiology and Immunology)

1. Long questions 1X10=10

A 17-year old student who has recently joined MBBS, came back to the hostel after the first
vacation. After entering her hostel room, she suddenly developed an episode of severe sneezing, and
dyspnea. She had to be admitted to the casualty and when asked, she gave a history of similar episodes
since her childhood.
a. What type of immune reaction is this? (3 marks)
b. Describe the pathogenesis of this condition and management. (7 marks)

II. Short notes 5X4=20

a. Bacterial cell wall- structure with labelled diagram
b. Spaulding’s classification of medical devices
c. PCR-principle and application pertaining to diagnostic microbiology
d. Automated blood culture system- types, principle, advantages over conventional system
e. Monoclonal antibody- hybridoma technology, application

III. Ultrashort notes 5X2=10

a. Selective media-definition with example
b. Define minimal inhibitory concentration (MIC) of an antibiotic and name the methods of detection of
MIC
c. Differences between innate immunity and acquired immunity
d. Subunit vaccines- Definition and examples
e. Applications of immunochromatographic test

Page 84 of 94
 SECTION B (Marks : 40)
(Blood Steam Infections, CVS Infections And Respiratory Infections
I. Long question 1X10=10
A 9-year-old boy was admitted with complaints of productive cough, chest pain, and shortness
of breath for past 3 days. Clinical examination revealed dullness over left sixth intercostal space on
percussion and crepitations and rales with reduced breath sounds over left sixth intercostal space on
auscultation. Chest X-ray showed homogeneous ground glass opacification in the left lower lobe. His
sputum was collected and subjected to microscopy (revealed Gram-positive cocci in pairs, lanceolate
shaped) and culture (revealed alpha-hemolytic, carrom coin colonies).
Questions:
What is your clinical and etiological diagnosis of these cases? (2 marks)
What are pathogenesis and clinical manifestations of these conditions? (3 marks)
Describe in detail about your approach for the laboratory diagnosis of this clinical condition? (3 marks)
What are the treatment modalities for these clinical conditions? (2 marks)

II. Short notes 5X4=20

a. Laboratory diagnosis of infective endocarditis
b. Laboratory diagnosis of cerebral malaria
c. Infectious mononucleosis- clinical features and laboratory diagnosis
d. Laboratory diagnosis of pulmonary tuberculosis
e. Laboratory diagnosis of influenza

III. Ultrashort notes 5X2=10

a. What is atypical pneumonia?
b. Standard agglutination test- For which clinical disease this test is done and its principle
c. Criteria for diagnosis of Dengue haemorrhagic fever
d. Diagnostic criteria for Catheter related blood stream infection
e. Oriental sore- agent and vector

Page 85 of 94
 MICROBIOLOGY
Paper - II
Time: Three Hours Maximum Marks: 80
Each Section to be answered in separate answer book
Illustrate your answers with suitable diagrams
SECTION A (Marks : 40)
(Gastrointestinal Infections, Liver, Genitourinary Infections, CNS Infections)
I. Long question 1X10=10
A 4-year-old boy developed severe watery diarrhea and vomiting. The stool collected has a rice
water type of appearance. It was sent for bacteriological analysis.
a. What is the probable etiological diagnosis of this condition? (2 marks)
b. Describe in detail the pathogenesis of this condition. (4 marks)
c. Add a note on its laboratory diagnosis. (4 marks)
II. Short notes 5X4=20
a. Risk factors and laboratory diagnosis of antibiotic associated diarrhoea
b. Laboratory diagnosis of hookworm infection
c. Markers of hepatitis B infection
d. Etiological agents and laboratory diagnosis of urinary tract infection
e. VDRL test – principle , merits and demerits

III. Ultrashort notes 5X2=10

a. Agents causing nongonococcal urethritis
b. Differences between pyogenic and aseptic meningitis in the cerebrospinal fluid
c. Triad of congenital rubella syndrome
d. Neurocysticercosis- agents, infective form, mode of transmission
e. National immunization schedule for polio

Page 86 of 94
 SECTION B
(Skin and soft tissue infections, Hospital infection control and Miscellaneous microbiology)
I. Long question 1X10=10
A 55-year-old male was admitted to the hospital with complaints of severe pain in the lateral aspect
of his left calf and small amount of pus discharge from the site. On physical examination, the local area was
found to be red, warm and tender. Pus was aspirated and was subjected to Gram stain (showed gram-positive
cocci in clusters), culture on blood agar (showed golden yellow pigmented beta haemolytic colonies).
a. What is the clinical diagnosis and its causative organism? (2 marks)
b. Enumerate various agents producing similar clinical condition. (2 marks)
c. List the infections caused by this organism. (2 marks)
d. List the virulence factors of this organism. (2 marks)
e. Briefly discuss the laboratory diagnosis. (2 marks)

II. Short notes 5X4=20

a. Recent change in 2016 biomedical waste management guidelines
b. Virulence factors of Bacillus anthracis
c. Clinical features and laboratory diagnosis of Melioidosis
d. Prevention of surgical site infections
e. Pathogenesis of gas gangrene, draw a neat labelled gram-stained morphology of Clostridium
perfringens

III. Ultrashort notes 5X2=10

a. Enumerate the agents causing dermatophytosis
b. Agents causing eumycotic mycetoma
c. Five moments of hand hygiene
d. India ink wet mount examination
e. Parasitic agents causing ocular infection

Page 87 of 94
 PATHOLOGY
PAPER - I
Time: Three Hours Maximum Marks: 80
Each Section to be answered in separate answer book
Illustrate your answers with suitable diagrams
SECTION A (Marks : 40)
(General Pathology)
I. Long question 1X10=10
Define apoptosis with examples. Discuss the biochemical features and mechanisms of apoptosis
(2+3+5=10 marks)
II. Short answer questions 5X4=20
a. Explain the pathogenesis and mediators of Granulomatous inflammation
b. Discuss the pathogenesis of edema in renal diseases
c. Discuss the role of Human papilloma virus in carcinogenesis
d. Discuss common causes and morphology of fatty liver
e. Write briefly Pathogenesis of Type I hypersensitivity
III. Very short answer questions 5X2=10
a. Write very briefly on the components of Virchow’s triad
b. What is the mechanism by which a patient with carcinoma lung develops Cushing syndrome?
c. What is the morphological appearance and the clinical significance of Barrett esophagus?
d. Name the biochemical abnormality and the classical morphological appearance of Gauchers
disease?
e. Enumerate the cardinal signs of acute inflammation
Section B
(Hematology, Transfusion Medicine and Reticuloendothelial system (Lymph Node, Spleen))
I. Long question 1X10=10
A 20 year old engineering student presented with complaints of easy fatiguability, bleeding gums.
No jaundice and organomegaly on examination. Routine hemogram showed Hb- 5gm/dl with normocytic
normochromic anemia; Reticulocyte count – <0.2%. TLC of 2100/mm3, DLC shows N20 L77 E2 M1. No
atypical cells and platelet count of 10,000/mm3.
a. What is the most probable diagnosis? (1)
b. What is the next investigation to be done to confirm the diagnosis and what are the findings
expected? (4)
c. What is the etiopathogenesis of this condition? (5)
II. Short answer questions 5X4=20
a. Write briefly on the laboratory diagnosis of multiple myeloma
b. Write briefly about pathophysiology of DIC
c. Discuss the pathogenesis and morphology of Burkitt lymphoma
d. Discuss the utility of ESR in clinical practice
e. Discuss the types and indications of Coombs test
III. Very short answer questions 5X2=10
a. A 20 week pregnant lady is evaluated for anemia. Hb 11gm%, RBC count – 6 million /mm3
with MCV – 60 fl, MCH – 21, MCHC- 25 and RDW of 12. TLC and Platelet are normal.
What is your diagnosis?
b. Mention two causes of prolonged PT?
c. What is Philadelphia Chromosome and in which condition it is seen?
d. Define massive splenomegaly and gives two causes
e. What is the pathogenesis of cerebral malaria in Plasmodium falciparum infection?

Page 88 of 94
 PATHOLOGY
PAPER II
Time: Three Hours Maximum Marks: 80
Each Section to be answered in separate answer book
Illustrate your answers with suitable diagrams
SECTION A (Marks: 40)
(Blood Vessels and CVS, Respiratory System, GIT, Hepatobiliary tract, CNS)
I. Long question 1X10=10
Describe the autopsy findings in lungs and heart in a 40 year old male with longstanding rheumatic
heart disease with mitral stenosis (5+5 marks)
II. Short answer questions 5X4=20
a. What are the macroscopic changes and complications seen in a case of bronchiectesis?
b. Tabulate the differences in CSF findings between tuberculous and pyogenic meningitis.
c. Explain the macroscopic and microscopic changes seen in alcoholic cirrhosis with a labeled
diagram
d. Discuss the morphological appearance of Primary pulmonary tuberculosis.
e. Discuss the adenoma- carcinoma sequence pertaining to colonic cancer.
III. Very short answer questions 5X2=10
a. Explain why smokers develop emphysema.
b. A 10 year old boy, known thalassemia develops gall stones. Mention the reason and the gross
appearance of gall stones
c. Explain the term “Interface hepatitis”.
d. Explain the basis of treebark appearance seen in syphilitic aneurysm.
e. Briefly enumerate the etiology of chronic pancreatitis.

Section B
(Renal, Male and female reproductive system, Breast, Endocrine, Musculoskeletal system, and Skin)
I. Long question 1X10=10
A 35 year old male presents with painless enlargement and heaviness of the right testis since 2
months. Ultrasound showed a hypoechoic and homogenous mass in the right testis. (4+4+2)
a) Discuss the investigations you would like to do to arrive at a diagnosis.
b) How are testicular tumors classified broadly?
c) Discuss the clinical relevance of this classification of testicular tumors.
II. Short answer questions 5X4=20
h. A 45 year old male presents with a swelling over the right knee joint of three months duration. X-
Ray reveals an expansile lytic lesion, predominantly in the epiphysial region of right lower femur
without any cortical breach. (2+2)
i) What is the likely diagnosis and why?
ii) Explain with a labeled diagram, the likely histological features of this condition.
b. Discuss the etiopathogenesis and urinary findings in post streptococcal glomerulonephritis.
c. Discuss the gross and microscopic appearance (with a diagram) of hydatid form mole.
d. Discuss the etiopathogenesis of multinodular goitre.
e. Explain the molecular basis of classification of Carcinoma breast.
III. Very short answer questions 5X2=10
a. Discuss briefly the genetic basis of Ewing sarcoma
b. Describe two histological features seen in papillary carcinoma thyroid
c. Write the risk factors for endometrial carcinoma
d. Mention the light microscopic and ultrastructural findings in minimal change disease of kidney
e. What are Virchows cells and in which disease are they seen?

Page 89 of 94
 PHARMACOLOGY
PAPER - I
Time: Three Hours Maximum Marks: 80
Each Section to be answered in separate answer book
Illustrate your answers with suitable diagrams
SECTION A (General Pharmacology and CNS)
I. Long Answer Question
1. A 26 year old man experiences frequent (twice in a month) episodes of sudden unconsciousness and
jerking movement of extremities for 2 minutes. After this he regains consciousness but is confused. He is
diagnosed to have epilepsy (generalised tonic clonic seizures).
a. List the first line antiepileptics for this patient and explain the mechanism of action of any one. (1+2)
b. What are the adverse effects that are common to many antiepileptics? (2)
c. If this patient is started on a first line agent, dose slowly titrated over two years to a maximum but
still uncontrolled, should he be switched to combination therapy? Justify with reason(s). (2)
d. Name two antiepileptics that are first line drugs for many types of seizure and mention the types of
seizure for which they are effective. Why are they effective against a wide range of seizures? (1+2)
II. Short Answer Questions
2. Write short notes for the following: 5 x 4 = 20
a. Explain the clinical implications of a drug possessing high volume of distribution.
b. Differentiate first order and zero order drug elimination with an example. Why should a treating
physician be aware of the order of elimination of the drug prescribed?
c. Explain the rationale for therapeutic drug monitoring.
d. Explain the mechanism of action and adverse effects of opioids.
e. Explain the pharmacological basis for using selective serotonin reuptake inhibitors in depression
III. Very Short Answer Questions
3. Explain the reasons for the following 5 x 2 = 10
a. Even though both benzodiazepines and barbiturates act on the same receptors, barbiturates have less
margin of safety than benzodiazepines,
b. Antipsychotics can cause parkinsonism.
c. Adrenaline is combined with lignocaine.
d. Sevoflurane is close to an ideal anaesthetic.
e. Ethyl alcohol is used in methyl alcohol poisoning.

Page 90 of 94
 SECTION B (Chemotherapy and GIT)

IV. Long Answer Question

4. A 36 year old man weighing 50 kg presents with evening rise of temperature, cough with expectoration
and weight loss for the past one month. Sputum microscopy reveals acid fast bacilli and chest
radiography shows cavitary lesions. (3 + 3 + 3 + 1 = 10)
a. Explain the treatment for this patient according to the national programme.
b. If this patient becomes a defaulter during therapy and later presents after one year how should he be
treated?
c. List three serious adverse effects of this therapy and mention ways to prevent / reduce each of them.
d. Mention briefly the mechanism of action of any one first line agent for this disease.
V. Short Answer Questions
5. Write short notes for the following 5 x 4 = 20
a. Explain the pharmacological basis for once a day aminoglycoside therapy.

b. Explain the treatment of chloroquine resistant falciparum malaria.

c. Explain the rationale for each constituent of oral rehydration salt

d. Explain the mechanism of action, uses and adverse effects of bisacodyl.

e. Differentiate the mechanism of action of alkylating agents and antimetabolites. Why anticancer
agents are administered in cycles with intervening periods of no treatment?

VI. Very Short Answer Questions

6. Explain the reasons for the following 5 x 2 = 10

a. The actions of penicillin and aminoglycosides are synergistic.

b. Fluoroquinolones should be used with caution in children.

c. Neomycin is used only as a topical agent.

d. Proton pump inhibitors should not be coadministered with any other acid suppressing agent.

e. Prokinetic agents can hasten the onset of action of coadministered drugs.

Page 91 of 94
 PHARMACOLOGY

PAPER - II

Time: Three Hours Maximum Marks: 80

Each Section to be answered in separate answer book

Illustrate your answers with suitable diagrams
SECTION A (Endocrines, Cardiovascular system and Blood)
I. Long Answer Question
1. A 10 year old boy presents with weight loss despite increased appetite. He has polyuria and polydipsia.
His fasting blood glucose is 170 mg/dL and 2 hour postprandial glucose is 250 mg/dL.
a. What is the drug of choice for this patient? Justify with reason(s). (½+1½)
b. Describe the principles / steps to be followed while initiating therapy with this drug.(3)
c. What are the glycemic goals of therapy in this patient? (2)
d. Differentiate insulin analogs and incretin analogs with an example for each. (3)
II. Short Answer Questions
2. Write short notes for the following: 5 x 4 = 20
a. Explain the mechanism of action and uses of loop diuretics
b. Explain the treatment of acute myocardial infarction
c. Differentiate unfractionated heparin and low molecular weight heparin. What are the clinical
implications of these differences?
d. Explain the mechanism of action and uses of low dose combined oral contraceptive pills.
e. Explain the treatment of hypertensive emergencies
III. Very Short Answer Questions
3. Explain the reasons for the following 5 x 2 = 10
a. Angiotensin converting enzyme inhibitors can cause hyperkalemia.
b. Oral iron is always administered as ferrous salts and not in ferric form.
c. Low dose aspirin is used for antiplatelet action.
d. Patients on nitrates require eight hour drug free interval.
e. Levothyroxine (T4) is preferred over triiodothyronine (T3) for hypothyroidism.

Page 92 of 94
 SECTION B
(Respiratory system, Autonomic nervous system, Autacoids & their antagonists, therapy of common
poisoning and heavy metal antagonists)
IV. Long Answer Questions
4. A 30 year old lady presents with repeated attacks (5 times a month) of unilateral throbbing headache
with vomiting and photophobia lasting for 8 to 10 hours for the past 6 months. Her neurological
examination is normal and is diagnosed to have migraine.
a. Which group of drugs is effective in relieving moderate to severe attacks in this patient? Explain how
it relieves a acute attack. (½+1½)
b. Explain the rationale / lack of rationale for the use of the combination, ergotamine with caffeine in
migraine. (2)
c. State the criteria for initiating prophylactic drug therapy in migraine. How long the prophylaxis
should be continued? (1+1)
d. List four drugs (belonging to different class) that are effective for prophylaxis in this patient and
explain how they reduce the frequency of attacks. (4)
V. Short Answer Questions
5. Write short notes for the following 5 x 4 = 20
a. Explain the uses and adverse effects of beta blockers.

b. Explain the treatment of acute severe asthma (status asthmaticus).

c. Mention the first line agents for chronic open angle glaucoma. Explain the rationale fr each.

d. Explain the mechanism of action and uses of dimercaprol.

e. Explain the treatment of organophosphorus poisoning.

VI. Very Short Answer Questions

6. Explain the reasons for the following 5 x 2 = 10
a. Adrenaline is the drug of choice for anaphylactic shock.

b. Anticholinergics should be used with caution in elderly.

c. Saline gargling is advised after inhaled corticosteroids.

d. Mast cell stabilisers are not effective for an acute attack of asthma.

e. N acetyl cysteine is used in paracetamol poisoning.

Page 93 of 94
 FORENSIC MEDICINE & TOXICOLOGY
Paper - I
Time: Three Hours Maximum Marks: 80
Each Section to be answered in separate answer book
Illustrate your answers with suitable diagrams
SECTION A (Marks : 40)
(Forensic Pathology, Clinical Forensic Medicine)
I. Long question 1X10=10
A forty year old male was found dead in the bushes. The police took custody of the corpse and sent
for medico legal autopsy. Enumerate the various methods of assessing the time since death. Explain how
time since death can be estimated with core temperature of the corpse and the various factors affecting
this method of time estimation (5+5)
I. Short answer questions 5X4=20
a. Explain the mechanism of skull fracture. What are the various skull fractures that can be caused due
to gun-shot injury to skull? (2+3)
b. A four month old baby was physically abused by his/her step mother. One fine day she had violently
shaken the baby and the child became unconscious. The child was brought to the hospital for
treatment. What are the findings in the baby that will give clues of abuse to the treating doctor? (5)
c. A pregnant woman, with 20 week gestation, belonging to low socio economic status came to OPD
for medical termination of pregnancy. What is the act that regulates the termination of pregnancy?
Explain the rules of the act and the punishments for non-compliance. (1+4)
d. A person found dead near to the beach due to drowning. What are the types of drowning? What is the
pathophysiology of death in above mentioned case? (1+4)
II. Very short answer questions 5X2=10
a. What is suspended animation?
b. What is corpus delicti?
c. What is café coronary?
d. Draw labeled diagram of the entry wound of rifled firearm, fired from close range.
e. What is acid phosphatase test?
Section B (Marks : 40)
(Medical Jurisprudence, Forensic Psychiatry, Forensic Toxicology)
I. Long question 1X10=10
A 45 year old male suffering from paranoid schizophrenia was found wandering in the street. Due to
his mental defect he assaulted a police officer during enquiry. What is the procedure to restrain him?
Explain the legal tests that will protect him from legal action by the police (4+6)
II. Short answer questions 5X4=20
a. A 16 year old boy was working in an oil mill. During the castor oil extraction process he accidentally
consumed the left over cake from the seeds. He became sick and was admitted to the hospital.
What is the active principle, mechanism of action and clinical features of this poison?
b. What is professional misconduct? What is the procedure for punishing the Doctor for professional
misconduct?
c. What is the consent? What are the rules of obtaining informed consent?
d. What is the treatment for removal of unabsorbed poison?
III. Very short answer questions 5X2=10
a. What is therapeutic privilege?
b. Enlist the conditions where magistrate inquest is conducted.
c. What is testamentary capacity?
d. What are various preparations of cannabis and its active principle
e. What are the clinical features of chronic lead poisoning?

Page 94 of 94