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Drug Study: Patient: B.V Age: 58y/o

Cyclophosphamide is an alkylating chemotherapy drug used to treat various cancers by interfering with DNA replication and protein synthesis. It works by alkylating DNA to inhibit cell division. Common side effects include vomiting, diarrhea, alopecia, and hematuria. Nursing interventions include encouraging fluid intake to promote uric acid excretion and monitoring for signs of cardiac or respiratory issues.
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0% found this document useful (0 votes)
127 views

Drug Study: Patient: B.V Age: 58y/o

Cyclophosphamide is an alkylating chemotherapy drug used to treat various cancers by interfering with DNA replication and protein synthesis. It works by alkylating DNA to inhibit cell division. Common side effects include vomiting, diarrhea, alopecia, and hematuria. Nursing interventions include encouraging fluid intake to promote uric acid excretion and monitoring for signs of cardiac or respiratory issues.
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DRUG STUDY

Patient: B.V Diagnosis: Invasive Ductal Carcinoma


Age: 58y/o Date: October 8, 2020

Name of Drug Mechanism of Action Indication Contraindication Side Effects Nursing Intervention

Generic Name: Inhibition of protein synthesis Its most important areas of use  Hypersensitivity, Vomiting • Encourage patient to
through interference with are non-Hodgkin's diarrhea drink 2000 – 3000
CYCLOPHOSPHAMIDE DNA lymphomas, multiple  Severe bone marrow mL/day to promote
replication by alkylation of myelomas, chronic lymphatic depression. Caution: weight loss excretion of uric
Brand Name:Cytoxan DNA leukemia, breast cancer, hematuria acid.
small-cell lung cancer,  Pregnancy,
Dosage: alopecia
neuroblastomas, and several  Liver or kidney • Alkalinization of the
PO: 1-5 mg/kg over 2-5 sarcomas. impotence
disease urine may be used to
IV: 40-50 mg/kg in sterility help prevent uric
divided doses acid nephropathy.
ovarian fibrosis
PO/IV: 1-5 mg/kg in divided headache
• Assess cardiac and
doses or 50-150 mg/m2 dizziness respiratory status for
dermatitis dyspnea,
Route: rales/crackles,
cough, weight gain,
IV,IO edema.

Frequency:

maintenance therapy is 1–5


mg/kg daily

Classification:

Alkylating agents

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