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Original DNA Sequence: TAC ACC TTG GCG ACG ACT: (Circle Any Changes)

This document provides a worksheet for students to practice identifying different types of mutations in DNA sequences. The worksheet contains an original DNA sequence and 5 mutated sequences. For each sequence, students are asked to transcribe the DNA into mRNA, translate the mRNA into amino acids, identify the type of mutation, and determine how the mutation affects the amino acid sequence or protein.

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Joelle Assaf
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0% found this document useful (0 votes)
185 views

Original DNA Sequence: TAC ACC TTG GCG ACG ACT: (Circle Any Changes)

This document provides a worksheet for students to practice identifying different types of mutations in DNA sequences. The worksheet contains an original DNA sequence and 5 mutated sequences. For each sequence, students are asked to transcribe the DNA into mRNA, translate the mRNA into amino acids, identify the type of mutation, and determine how the mutation affects the amino acid sequence or protein.

Uploaded by

Joelle Assaf
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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Class: 11 Subject: Life Science

HW:Types of Mutation

Name: --------------------------------- https://youtu.be/HIuv9ifnb14

_________________________________________________________________________________________________

DNA Mutations Practice Worksheet


DIRECTIONS: Transcribe and translate the original DNA sequence. Then, do the same for each mutated
DNA sequence. Then, determine the consequence, if any, for each mutation, by circling your choice for
each question. You will need a Genetic Code Chart.

Original DNA
TAC ACC TTG GCG ACG ACT
sequence:
mRNA transcript:

amino acids:

Mutated DNA
TAC ATC TTG GCG ACG ACT
sequence #1:
mRNA transcript:
(Circle any changes)
amino acids:
Type of
Point Frameshift
mutation Substitution Insertion or Deletion
 
(Circle one.)
How did the
mutation
affect the 1 amino 1 amino acid All the amino acids
Premature No stop
amino acid No change acid added/ changed after the
stop signal signal
sequence changed deleted point of mutation
(protein)?
(Circle one.)

Mutated DNA
TAC GAC CTT GGC GAC GAC T
sequence #2:
1
mRNA transcript:
(Circle any changes)
amino acids:
Type of
Point Frameshift
mutation Substitution Insertion or Deletion
 
(Circle one.)
How did the
mutation
affect the 1 amino Prematur 1 amino acid All the amino acids
No stop
amino acid No change acid e stop added/ changed after the
signal
sequence changed signal deleted point of mutation
(protein)?
(Circle one.)

Mutated DNA
TAC ACC TTA GCG ACG ACT
sequence #3:
mRNA transcript:
(Circle any changes)
amino acids:
Type of
Point Frameshift
mutation Substitution Insertion or Deletion
 
(Circle one.)
How did the
mutation
affect the 1 amino Prematur 1 amino acid All the amino acids
No stop
amino acid No change acid e stop added/ changed after the
signal
sequence changed signal deleted point of mutation
(protein)?
(Circle one.)

Mutated DNA
TAC ACC TTG GCG ACT ACT
sequence #4:
mRNA transcript:
2
(Circle any changes)
amino acids:
Type of
Point Frameshift
mutation Substitution Insertion or Deletion
 
(Circle one.)
How did the
mutation
affect the 1 amino Prematur 1 amino acid All the amino acids
No stop
amino acid No change acid e stop added/ changed after the
signal
sequence changed signal deleted point of mutation
(protein)?
(Circle one.)

Mutated DNA
TAC ACC TTG GGA CGA CT
sequence #5:
mRNA transcript:
(Circle any changes)
amino acids:
Type of
Point Frameshift
mutation Substitution Insertion or Deletion
 
(Circle one.)
How did the
mutation
affect the 1 amino Prematur 1 amino acid All the amino acids
No stop
amino acid No change acid e stop added/ changed after the
signal
sequence changed signal deleted point of mutation
(protein)?
(Circle one.)

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