Virus, bacteria & odor control

for textiles

March 16, 2020

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 PFC-free
Sustainability water repellent:
HeiQ Eco Dry Rapid
is at the core of our business. polyester dyeing:
HeiQ is bluesign
Award-winning partner since
For HeiQ, sustainability HeiQ Clean Tech 2011
encompasses not only economic,
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principles, but also product
quality. Our purpose is to 50% less
insulation yet Oeko-tex conform
help make textiles
100% warmth: products
better. Destroys HeiQ XReflex
Coronavirus in
seconds
HeiQ Viroblock Silver-free
bio-based odor
control:
HeiQ Fresh FFL

4
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Concord, North Carolina USA ▪ Chemical reactions
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17 major recognitions in 15 years
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HeiQ scientific board
Martin Loessner ETH Zürich
Microbiology & food sciences
Prof. Dr. Switzerland

Clemens Holzer Montanuniversitaet Leoben

Polymer science & processing
Univ. Prof. Dipl. Eng. Dr. mont. Austria

Hyung Gyu Park POSTECH

Nanotechnology & process engineering
Prof. Dr. South Korea

Thierry Pelet EPFL Lausanne

Molecular biology & virology
Dr. Switzerland

Wey Yang Teoh

Australia Nanotechnology & Photocatalysis
Dr.

Hendrik Tevaearai
Switzerland Cardiology & medical sciences
Prof. Dr. med., EMBA HSG

Paul Collins Deakin University

Engineering & sports physiology
Assoc. Prof. Dr. Australia

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Biomaterials & materials science
Assoc. Prof. Dr. Australia

9
HeiQ research network
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team of 12 chemists
HeiQ achieves its research
objectives primarily through a
boundless research network
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with researchers at universities and
institutes around the world
Today dozens of PhD’s work on HeiQ
projects

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HeiQ key innovation families

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Antiviral and antimicrobial range

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What is the issue?

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Viruses
What is a virus?
▪ Extremely small and infectious substances that reproduce by
invading a living host cell. The host cell replicates and releases
the new viruses which go on to infect other cells
▪ Viruses usually infect specific cell types and most viruses infect
only a few species of plants or animals; some infect only humans
What is an enveloped virus?
▪ Many pathogenic viruses are enveloped by a lipid (fatty)
membrane
▪ The lipid membrane protects the genetic material inside the virus
and provides additional functions for cell attachment,
morphogenesis and transmission
▪ Enveloped viruses represent more than 60% of all existing
viruses and include major human pathogens
▪ Examples: coronavirus, human and avian influenzas, H5N1,
Herpes, hepatitis, and AIDS
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Bacteria
What are bacteria?
▪ Single cell organisms capable of rapidly reproducing by cell division
▪ A natural part of the environment, and present in large numbers
inside and on the outside our bodies
▪ Most bacteria are harmless; however some bacteria can cause
harmful disease
▪ Bacteria can be broadly classified as gram positive or gram negative
depending on the structure of the cell wall
▪ Gram positive bacteria are primarily responsible for body odors:

Gram positive bacteria Gram negative bacteria

▪ Staphylococcus aureus ▪ Escherichia coli
▪ MRSA ("golden staph") ▪ Klebsiella pneumoniae
▪ MSSA ▪ Salmonella typhimurium
▪ Listeria monocytogenes ▪ Pseudomonas aeruginosa
▪ etc. ▪ etc.
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Textiles: a vector for viruses and bacteria
Bacteria need 4 conditions to survive & reproduce:
Textiles provide
a large surface
area for
Bacteria Fat & protein Hosting bacteria
Warmth Moisture
(from human sweat) surface

Viruses can persist on surfaces and remain infectious

E.g research has shown that the human coronavirus (SARS-CoV)
can persist for up to 2 days on surgical gowns at room
Viruses
temperature.1)

[1] Kampf, G., Todt, D., Pfaender, S. and Steinmann, E., 2020. Persistence of coronaviruses on inanimate surfaces and its inactivation with biocidal agents. Journal of
Hospital Infection.
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Infection & transmission 2)

▪ Many viruses and bacteria are

pathogens that can lead to severe
sickness and mortality
▪ Thousands of deaths every year can
result from transmission of pathogenic
viruses and bacteria 1)
▪ Viruses and bacteria can remain 2)
active on textile surfaces from days to
months [2]

1) K.Sack “Hospital Infection Problem Persists”, New York Times (April 13, 2010).
2) A.Kramer, I.Schwebke, G.Kampf (2006) "How long do nosocomial pathogens persist on
inanimate surfaces? A systematic review", BMC Infectious Diseases, 6(130).

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Textiles: a vector for viruses and bacteria
▪ Textiles from clothing, gowns, drapes and sheets provide an
ideal surface for contamination with viruses and bacteria.
Contaminated textiles can act as a surface for transmitting
pathogens 1, 2, 3)
▪ Antiviral and antibacterial textiles can play a part in an
overall strategy to address transmission of bacteria and
viruses in sensitive environments
▪ Preventing bacteria and viruses from contaminating textiles
can play a role in minimizing opportunities for transmission 4)
▪ Textiles treated with HeiQ Viroblock are designed to reduce
virus and bacteria contamination of textile fabrics in
sensitive environments
1) A.Kramer, I.Schwebke, G.Kampf (2006) "How long do nosocomial pathogens persist on inanimate surfaces? A systematic
review", BMC Infectious Diseases, 6(130).
2) A.Neely & M.Maley (2000) "Survival of Enterococci and Staphylococci on Hospital Fabrics and Plastic", Journal of Clinical
Microbiology, 38, p.724–726.
3) RW.Sidwell, GJ.Dixon, E.McNeil (1966) "Quantitative Studies on Fabrics as Disseminators of Viruses. I. Persistence of
Vaccinia Virus on Cotton and Wool Fabrics", Applied Microbiology, 14(1), p.55-59.
18
4) D.Höfer “The Role of Textiles in Chains of Infection”, AMH Magazine, (April 2010).
Bacteria is a reason for bad odor in textiles
Synthetic fibers are generally perceived Which textiles are perceived as the most smelly?
to be much smellier than natural fibers
By sweating we transport nutrients like
lipids and sugars into textiles on which
bacteria can feed and rapidly grow by
doubling every 20 minutes
Bacteria cause bad odors and
discomfort
The odor development is particularly
strong on synthetic textiles, already after
few hours Wear trial at University of Alberta1

[1] McQueen, Rachel H., et al. "Retention of axillary odour on apparel fabrics." Journal of the Textile Institute 99.6 (2008): 515-523.
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What is the solution?

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HeiQ’s three innovative technology platforms
Technology platform

Bio-based
Vesicle technology Silver
amino sugar polymer
HeiQ products
HeiQ Pure TAG

HeiQ Viroblock NPJ03 HeiQ Pure SPQR

Target performance

Antiviral & Antimicrobial

Antimicrobial
antimicrobial odor control

For non-wash medical non-woven For clothing and washable items

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 HeiQ Viroblock NPJ03

HeiQ Viroblock NPJ03 – antiviral technology

▪ Effective against common harmful viruses such as Technical USPs
influenza and coronavirus
✓ Non-dangerous good: logistics
▪ Combination of innovative antibacterial silver and and storage convenient
antiviral cholesterine depleting lipid vesicle ✓ Can be applied to all types of
technologies fabrics and non-wovens
▪ Kills bacteria and destroys viruses in minutes ✓ Standard continuous wet-
processing applications
▪ Effective protection against contamination and (padding, kiss-roll etc.)
transmission of viruses and bacteria that use textile ✓ Application 5% to 20% w.o.f.
as a hosting surface
▪ Harnesses the natural antiviral and antibacterial
properties of silver
▪ Ideal for disposable non-woven medical garments,
face masks, drapes, air filters, and other non-wash
items
Oekotex, Bluesign, ZDHC: pending for approval
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 HeiQ Pure TAG

HeiQ Pure TAG – based on recycled silver

▪ Inhibiting the growth of all bacteria on textiles
Technical USPs
▪ Non-leaching antimicrobial agent
✓ Non-ionic = best compatibility
▪ Especially suitable for protective textiles
with most textile finishings
▪ Highly resistant to washing and dry cleaning ✓ 2 year storage stability
✓ No shade influence
▪ Harness the natural properties of silver, based on
✓ No impact on the hand
silver salt from recycled silver source
✓ No foaming behavior, suitable
▪ Bluesign approved, ZDHC, Oekotex Class 1-4 on jets
EPA registered ✓ High bath stability
✓ Application 0.5% to 1.5% w.o.f.

Based on silver salt from recycled silver source 23

 HeiQ Pure SPQR

HeiQ Pure SPQR – hybrid efficiency

▪ Excellent dual-action properties:
antimicrobial and odor absorbing
Technical USPs
▪ Contains >60% bio-based amino sugar polymer ✓ Non-dangerous good: logistics
(ASP) and silver salt based on recycled silver and storage convenient
✓ Best product for exhaust
▪ ASP binds odors emitted from the body &
application (e.g. seamless
refreshes at every wash, prevents permastink
garments for sport)
▪ Especially suitable for textiles worn next to the skin ✓ Excellent wash durability
✓ Flexible application by padding
▪ Bluesign approved, ZDHC, Oekotex Class 1-4
or exhaust
EPA registered, USDA bio-preferred certified ✓ Super bath-stable
✓ Application 4% to 6% w.o.f.

Based on silver salt from recycled silver source 24

Vesicle & silver technologies
Highly efficient antiviral and antibacterial effect

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 HeiQ Viroblock NPJ03

Protection against viruses and bacteria

▪ HeiQ Viroblock provides textiles with effective protection against contamination and
transmission of viruses and bacteria
▪ A unique combination of two leading HeiQ technologies:
▪ HeiQ vesicle technology targets lipid-enveloped viruses providing rapid virus destruction
▪ HeiQ silver technology targets both bacteria and viruses kills and inhibits replication

Virus examples (enveloped type): Bacteria examples:

▪ Coronavirus (SARS-CoV, Covid-19, etc) ▪ Staphylococcus aureus
▪ H1N1 ▪ MRSA ("golden staph")
▪ H5N1 ▪ MSSA
▪ HIV ▪ Listeria monocytogenes
▪ RSV ▪ Escherichia coli
▪ Herpes Simplex ▪ Klebsiella pneumoniae
▪ Sendai ▪ Salmonella typhimurium
▪ etc. ▪ Pseudomonas aeruginosa
▪ Candida albicans (yeast)

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 HeiQ Viroblock NPJ03

HeiQ Viroblock – Vesicle component

▪ HeiQ Viroblock vesicle technology
functions by directly targeting the lipid
envelope (membrane) surrounding the Vessicle structure
virus
▪ The vesicle structures rapidly deplete
cholesterol from the viral envelope
exposing and destroying the virus
▪ The vesicles destroys the viruses
through a physical contact mechanism
Cholesterol
in seconds
(lipid) envelope

Virus
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 HeiQ Viroblock NPJ03

HeiQ Viroblock – Silver component

6)

▪ Small silver particles are potent “antimicrobial and

antiviral agents” due to high surface area to volume
ratio and unique chemical and physical properties 5)
▪ Small silver particles are effective against viruses,
effectively eliminating them following short
A) Transmission electron micrograph showing an amorphous silicon
exposure of isolated viruses to silver 5) dioxide aggregate particle (gray structure) together with numerous
supported silver metal particles (dark spots). (B) Scanning transmission
▪ Silver interacts with the sulfur-bearing moieties of electron micrograph of the structure shown in panel A, providing better
contrast between the silica structure (gray) and the silver metal particles
viruses and can form complexes with electron donor (bright spots). (C) Higher magnification of the region in panel B enclosed
groups leading to inhibition of post-entry stages of in a box. The silver metal particles are typically between 1 and 10 nm in
diameter.
infection through blocking of viral proteins
▪ HeiQ small silver particles contribute to a broad-
spectrum of anti-viral mechanisms that are not
prone to inducing resistance

5) Stefania Galdiero et. al. (2011) “Silver Nanoparticles as Potential Antiviral Agents”, molecules 2011, 16, 8894-8918.
6) Egger et. al., 2009. Antimicrobial properties of a novel silver-silica nanocomposite material. Appl. Environ. Microbiol., 75(9), pp.2973-2976. 28
 HeiQ Viroblock NPJ03

How does it work?

Untreated fabric HeiQ Viroblock treated fabric

▪ Textiles treated with HeiQ Viroblock actively

▪ Textiles provide an ideal surface for
inhibit viruses and kill bacteria upon contact
harboring viruses and bacteria
▪ By keeping the textile free of viable viruses
▪ Over the time, viruses and bacteria be re-
and bacteria HeiQ Viroblock treated textiles
transmitted from the textile (eg. contact with
help to minimize the potential for re-
other surfaces)
transmission of pathogens from textiles
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 HeiQ Viroblock NPJ03

Sendai virus time series

▪ Non-woven fabric treated with HeiQ Viroblock NPJ03
▪ Residual virus infectivity tested according to a modified ISO 20743 method (Sendai virus)

▪ Rapid anti-viral effect demonstrated within 2 to 5 minutes 30

 HeiQ Viroblock NPJ03

Staphylococcus aureus time series

▪ Polyester fabric treated with HeiQ Viroblock NPJ03
▪ Time series effectiveness based on modified ISO 20743 test method

The time series study

showed >99% effect
against
Staphylococcus aureus
within 20 min

▪ Rapid anti-bacterial effect demonstrated within 20 to 30 minutes

 HeiQ Viroblock NPJ03

Antimicrobial effect on bacteria and yeast

▪ Non-woven fabric treated with HeiQ Viroblock NPJ03
▪ Antimicrobial activity tested according to a ISO 20743

▪ Broad spectrum activity against gram negative and gram positive bacteria (and yeast)
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 HeiQ Viroblock
aerosol challenge testing

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Aerosol challenge test (antiviral effect)
Method
▪ Test mask mounted and sealed within a test
chamber
▪ A nebulizer delivers an aerosol of the target
virus inoculum to the upstream side of the
mask
▪ A vacuum draws air through the mask
▪ A collection dish placed below the mask
downstream collects aerosol droplets that
pass through the mask sample
▪ The reduction in infectivity with and without
mask is calculated as an indicator of
effectiveness

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 HeiQ Viroblock NPJ03

Aerosol challenge test (antiviral effect)

▪ FFP2 face masks (untreated control vs HeiQ Viroblock
treated)
Log reduction % reduction
Study ID Agent Control Viroblock Control Viroblock

798-110 H1N1 (Human Influenza A) 3.63 5.38 99.9766% 99.9996%

798-111 H5N1 (Avian Influenza A) 2.86 4.86 99.862% 99.999%

798-112 229E (Human Coronavirus) 2.90 4.48 99.874% 99.997%
H7N9 (2013 Influenza A
798-114 1.93 4.24 98.825% 99.994%
virus)
RSV (Respiratory Syncytial
798-115 1.40 3.10 96.02% 99.92%
Virus)
Mycobacterium terrae (ATCC
798-116 0.26 1.98 45.05% 98.95%
15755)

▪ HeiQ Viroblock NPJ03 (Viroblock) treated FFP2 mask shows

dramatically (>10 times) improved reduction in virus infectivity
▪ Effective against key virus types: H1N1, H5N1, H7N9,
Coronavirus, and RSV
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Antiviral efficacy test (ISO 18184)
1200
Determination of antiviral activity of textile

Residual Viral Infectivity

1000 % Inhibition: 22.3 99.3 39.8 100
products 800

▪ ISO 181841) measures the property to 600

give the morphological change or 400

structural damage to the surface 200

protein of virus 0
Control Untreated Treated SM Untreated Treated FFP2
SM FFP2 (0) (0)
▪ A reference cloth used to verify the
stability of the test virus on a textile
fabric
▪ Infectivity titre of virus is measured
with the number of infectious viral
particles present per unit volume in a
cell lysate or in a solution
96 wells microplate for TCID50 method
Please consult your local testing laboratories to carry out ISO18184 tests if needed

1) ISO 18184:2019, Textiles — Determination of antiviral activity of textile products, International Organization for Standardization (ISO) 36
 HeiQ Viroblock NPJ03

Misting study results

▪ Cotton fabric (Untreated control vs HeiQ Viroblock
treated)
▪ Exposure to Human influenza A (H1N1)
Time
Study Agent Control Viroblock
(mins)
H1N1 (Human
798-119 60 0.63 3.35
Influenza A)
120 0.15 2.47
180 0.40 2.47

▪ HeiQ Viroblock treated fabric shows dramatically

improved reduction (>100 times) in virus infectivity
over a 3 hour period

37
 HeiQ Viroblock NPJ03

FFP2 control facemask vs FFP2 treated HeiQ Viroblock

control

38
 HeiQ Viroblock NPJ03

Misting study results

▪ FFP2 face masks (untreated control vs HeiQ Viroblock
treated)
FFP2 HeiQ
Study Agent FFP2 Control
Viroblock
798-126 H1N1 (Human Influenza A) 1.11 3.71

▪ HeiQ Viroblock treated FFP2 mask shows dramatically

(>100 times) improved reduction in virus infectivity
(mist contact)

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 HeiQ Viroblock NPJ03

Face mask performance comparison

▪ FFP3 masks have a higher resistance to breathing than FFP2 masks leading to higher metabolic
cost. Higher resistance can lead to greater fatigue and exertion for prolonged periods of mask
wearing. 1, 2)
▪ FFP2 mask material treated with HeiQ Viroblock showed similar virus reduction to FFP3 mask
material 3)
▪ Masks treated with HeiQ Viroblock provide significantly greater protection against surface
contamination of the mask material 4)
Log reduction (H1N1 human influenza)
Aerosol protection 3 Surface protection 4
Metabolic cost Max breathing HeiQ HeiQ
Mask type Control Control
(W/m2) 1 resistance (Pa) 2 Viroblock Viroblock
FFP2 20 70 5.22 1.11 3.71

FFP3 40 100 5.11

[1] Roberge, R.J., Kim, J.H. and Coca, A., 2012. Protective facemask impact on human thermoregulation: an overview. Annals of occupational hygiene, 56(1), pp.102-112.
[2] Senić, Ž., Ilić, M., Radojković, A., Rajić, D. And Karkalić, R., Efficiency of Respiratory Protection Devices Against Bird Flu Virus. 4th International Conference on Defensive Technologies, OTEH 2011,
2011 Oct 6-7th.
[3] Viroblock, Aerosol study 798-121
[4] Viroblock, Misting study 798-126
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 HeiQ Viroblock NPJ03

Droplet breakthrough
▪ A cough can release around 100,000 droplets into the air 1)

▪ A scenario of a mask exposed to all 100,000 droplets yields different resulting numbers
of viable virus droplets passing through:
Viable droplets passing
Mask Log reduction [2] % reduction
through mask

FFP2 control 3.63 99.9766% >23

FFP2 & HeiQ Viroblock 5.38 99.9996% <1 !

▪ HeiQ Viroblock treatment enhances the level of virus protection for masks by >10 times

1) Gerone, P.J., Couch, R.B., Keefer, G.V., Douglas, R.G., Derrenbacher, E.B. and Knight, V., 1966. Assessment of experimental and natural viral aerosols. Bacteriological reviews, 30(3), p.576.
[2) Viroblock, Aerosol study 798-110 41
Recycled silver &
bio-based amino sugar polymer
Antimicrobial odor control

42
 Silver salt based on
recycled silver
Harness the natural antimicrobial properties of silver.

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Silver – the sustainable technology
Ag2S Unique qualities of silver:
Acanthite Ore ▪ No human & skin toxicity 1)
▪ Effective in very low concentrations 2)
Ag2S Ag0 ▪ Low risk for bacteria resistance 3)
▪ Immediately de-activated in waste
water treatment plant & effluent
sludge/land-fill 4)
HeiQ Pure
Disposal
(Ag0 or Ag+) 1) US Environmental Protection Agency, R.E.D, 1991
2) Gilchrist T, et al., Biomaterials, 1991, 12: 76-78
3) Damm, C. et al., Soft materials, 2006, 3:71-88
Textile Product 4) Kägi, R. et al., Environmental Science, & Technology, 2011

*Cradle to Cradle is a holistic economic, industrial, social framework that seeks to create products that are efficient but also essentially
waste free. 44
 HeiQ Viroblock NPJ03 HeiQ Pure SPQR HeiQ Pure TAG

HeiQ Pure – Mode of Action

HeiQ Pure coating The silver ions generated from HeiQ Pure
stops bacterial growth and odor development
Filament → Very low likelihood of resistance building1
Moisture from
Ambient
1.1 Perforates the cell membrane

Silver 2.2 Interferes with respiration

Storage
SILVER 3.3 Stops reproduction

Ag+
Silver Bacterium
Ions

[1] Jakobsen et.al. Int. Jour. Of Antimicrobial Agents, 2011 45

Safe to the Skin
Leaching technologies like Triclosan
migrate out of the textile and potentially Untreated Triclosan
onto the skin; a “halo” of an inhibition
zone is detectable. They should not be
used close to skin.
Leaching
Halo-Effect

Non-leaching technologies like silver do

not migrate away from the textile; the
bacteria can grow in the immediate
proximity of a treated textile; there is no
migration of bioactive silver onto the
skin

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Silver & skin flora – Study performed by Hohenstein
Hohenstein researchers carried out field
study into the effect of silver treated
clothing on skin flora and microclimate
A total of 60 healthy volunteers took part in antimicrobial
treated
this trial for a period of 6 weeks
Trials show that the natural skin flora are
unaffected even after long periods of wear
As conclusion, in this field study the skin
flora and microclimate of healthy skin
remained unaffected by the silver treated t-
shirts that were worn next to the skin

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 HeiQ Pure SPQR

Amino sugar polymer:

Bio-based odor adsorber
A key ingredient in HeiQ’s best odor control technology:
HeiQ Pure SPQR

48
 HeiQ Pure SPQR

Sweat odor: Did you know?

▪ Sweat does not smell
▪ Gram-positive bacteria, eg. Staphylococcus Aureus found on skin, produce the bad smell
▪ By sweating we transport moisture and nutrients into textiles which feed the bacteria
▪ Bacteria break down fat and protein into a smelly acids (VOCs) similar to rancid butter*

Sweat odors need 5 precursors to emerge

HeiQ Pure SPQR tackles in two actions

Fat & protein Hosting

Bacteria Warmth
(from human sweat)
Moisture
surface
Sweat odor VOCs

*Butanoic acid 49
 HeiQ Pure SPQR

Detailed mode of action of the Amino Sugar Polymer

Binding of odor molecules via salt bridge (chemisorption mechanism): Effect on odor molecule:
OH OH
O
OH OH
OH O H3C
OH O O OH OH
OH
O H3C O
O HO
O
O
O HO
NH2
OH O
O NH3
+ free short chain fatty acid is
HO HO HO
HO NH2
Propionic acid +
NH2 volatile = smell perceived
HO n NH2
HO NH3 n
(odor molecule / salt bridge
Amino Sugar Polymer (ASP) short chain fatty acid) salt bridge O
OH
H3C -
O
O
H3C O 1
O -
OH
OH
OH
OH
OH
OH
OH OH O HO R
O OH OH OH
OH
OH OH O OH OH O OH OHO OH O OH H3C -
O O O +
HO
O O
HO NH2O
OHO
O NHO
2 O
OHO O NH2
O
O O
HO O NH2O OHO ONH2 O
O
OHO NH2 HO NH3
HO NH2 HO HONH2 HO NH
HO
2 HO NH2 HO HO NH2
HO NH2 HO NH2 HO NH2 HO NH2

bound short chain fatty acid is

ASP film on fiber surface non volatile = no smell perceived

▪ The amino groups (-NH2) chemisorb short chain fatty acids (-COOH) and form a salt
bridge (-NH3+ /-COO-) resulting in mineralization of odor molecules1
▪ Action is directly between odor molecules and the amino sugar polymer. NOT an
antimicrobial mechanism2

[1] M. V. Shamov, S. Yu. Bratskaya, and V. A. Avramenko, Interface Science 249, 316–321 (2002)
[2] L. John R. Foster, Julian Butt, Biotechnology Letters (2011) 33:417–421
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How can HeiQ Viroblock
and HeiQ Pure
be tested?

52
 HeiQ Viroblock NPJ03 HeiQ Pure SPQR HeiQ Pure TAG

HeiQ Yogurt Bac test – Qualitative method

Fast and simple test for quick proof of concept
Procedure:
Adding diluted sterile UHT (Ultra High Temperature) milk and non-
pathogenic blended (Yogurt/bifidus) bacteria sample onto fabric
(incubation: 15 hours at 40°C)

Evaluation:
pH-measurement for control purposes:
Fail pH< 5.5 (lactic acid present)
Pass pH> 6.5 (no noteworthy amount of lactic acid)
Qualitative olfactory evaluation:
Fail Odor present
Pass Odor not present

*QC = Quality Control test method (at cost)

53
 HeiQ Viroblock NPJ03 HeiQ Pure SPQR HeiQ Pure TAG

Bacteriostatic efficacy test (ISO 20743)

Quantitative test method for the determination of bacteriostatic
activity on textiles including nonwovens

▪ This test method is applicable to all

textile products including material
for apparel, home textiles, cloth,
wadding, thread etc.
Untreated
▪ Widely accepted method for textile
samples
▪ Specified organism:
Staphylococcus aureus
Klebsiella pneumoniae
Treated with
HeiQ Pure TAG
*QA = Quality Assurance test method (at cost if used for QC purpose)
54
[1] ISO 20743:2013, Textiles — Determination of antibacterial activity of textile products, International Organization for Standardization (ISO)
 HeiQ Viroblock NPJ03 HeiQ Pure SPQR HeiQ Pure TAG

Testing Method – ISO 20743

55
[1] ISO 20743:2013, Textiles — Determination of antibacterial activity of textile products, International Organization for Standardization (ISO)
 HeiQ Viroblock NPJ03 HeiQ Pure SPQR HeiQ Pure TAG

ISO 20743 results

▪ HeiQ Pure TAG treated samples of PES and CO both show 99,999%
antimicrobial activity versus Staphylococcus aureus and versus Klebsiella
pneumoniae

56
 HeiQ Pure SPQR

Odor emission test (adapted ISO 17299-2)

Test method for measuring
VOC emission from sweaty
textile apparel

ISO 17299-2 Adapted ISO 17299-2

Diluted propionic acid (=main Rate of Desorption of
odiferous metabolite in human treated fabric
Type of VOC Ammonia
sweat) → Artificial body odor
solution (ABOS)

VOC is inoculated VOC is inoculated directly on

Inoculation into the air (in textile to simulate the
the bag) absorption of the sweat
Fabric sample treated with HeiQ Fresh
Measurement of Adsorption Desorption

*QA = Quality Assurance test method (at cost if used for QC purpose)
57
 HeiQ Pure SPQR

Amino sugar polymer sweat odor capturing effect

16 O
▪ The perception of sweat mimicking H3C
OH

PAc gas phase equilibrium concentration

odors is drastically reduced as Amino 14 free short chain fatty acid is
volatile = smell perceived
sugar polymer is able to mineralize the
12
most prominent odor forming
molecules originating from sweat 10
components (short chain fatty acid, e.g.

[ppm]
OH
8 O

propionic acid), by forming a salt bridge H3C -

O HO
O 1
R
+

between the amino group of the amino 6 HO NH3

bound short chain fatty acid is
sugar polymer and the carboxylic acid 4
non volatile = no smell perceived

of the odorous molecule

2
▪ The volatility is strongly reduced - 93.8%
0
▪ The mode of action does not affect the Untreated PES PES treated with HeiQ
microbe flora FreshSPQR
Pure FFL (4%)
(6%)

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Where can HeiQ Viroblock
and HeiQ Pure be used?

59
HeiQ Viroblock application areas
All fiber types
Non-wovens
▪ HeiQ Viroblock NPJ03 is ideal for non-woven
products:
▪ Face masks
▪ Air filters
▪ Medical non-wovens (eg. surgical gowns,
scrubs, drapes, curtains etc.)

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HeiQ Viroblock’s unique selling points
▪ HeiQ Viroblock treated textiles help to
reduce the risk of viral and bacterial
persistence on dry inanimate surfaces,
thereby lowering the potential for
transmission
▪ HeiQ Viroblock confers antiviral &
antibacterial effect to textiles
Every few years, epidemics breakout globally or regiionally
▪ HeiQ Viroblock is a Swiss technology causing disruption to lifes, sometimes leading to social
distress, financial market crashes and economic
▪ HeiQ Viroblock technologies effectiveness downturn.
has been tried and tested as active against Photo: Commuters wearing protective masks in a MTR
viruses that commonly affect human health. station in Hong Kong on the 5th day after first confirmed
case of novel coronavirus (Covid-19) in Hong Kong.
Photo from CNBC, Paul Yeung | Bloomberg

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HeiQ Viroblock ingredient brand and hangtag
HeiQ Viroblock hangtag

HeiQ Viroblock logo SWISS TECH INSIDE logo

Sewn-in label

Requirements to use HeiQ Ingredient Brand elements:

▪ Fabric testing: The HeiQ treated fabric has to be tested prior to the
hangtag application.
A test report needs to be submitted for HeiQ’s review.
▪ Acceptable tests for HeiQ Pure treated fabrics: ISO 18184.
▪ Third-party laboratory tests are accepted. HeiQ does not offer ISO 18184 test.
▪ Trademark license agreement: Use of the hangtags requires adherence to HeiQ’s standard license
agreement. Providing the brand company name and contact person is mandatory.
▪ Strict product label claim approval by HeiQ required (no direct or implied healthcare claims allowed!)
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HeiQ Pure application areas
Garments
▪ Underwear, sports apparel, hiking
shirts, fleece, socks, linings,
footwear and gloves
▪ Casual and business wear
▪ Home textiles, such as towels and
bed linens
▪ Ideal for next-to-skin products
▪ Applicable to all fabric types
▪ Uniforms in clinical and care
facilities
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HeiQ Pure ingredient brand and hangtag
HeiQ Pure hangtag

HeiQ Pure logo SWISS TECH INSIDE logo

Sewn-in label

Requirements to use HeiQ Ingredient Brand elements:

▪ Fabric testing: The HeiQ treated fabric has to be tested prior to the
hangtag application.
A test report number needs to be submitted for HeiQ’s review.
▪ Acceptable tests for HeiQ Pure treated fabrics: ISO 20743, JIS L 1902:2002, AATCC 100.
▪ Tests are changed at cost. Third-party laboratory tests are accepted.
▪ Trademark license agreement: Use of the hangtags requires adherence to HeiQ’s standard license
agreement. Providing the brand company name and contact person is mandatory.
▪ Strict product label claim approval by HeiQ required (no direct or implied healthcare claims allowed!)
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 Regulatory coverage of
HeiQ Viroblock and HeiQ Pure

65
Regulations & labels
All HeiQ Pure & HeiQ Viroblock products are
thoroughly tested for Safety, Sustainability and
Environment
▪ Harmless to skin and body
▪ Uses a minimum of active ingredient, best in
industry class
The family contains products and actives compliant
with EU BPR, EU REACH, US FIFRA, JP METI, JP
SEK, CN IECSC, TK BPR, bluesign approved and
OEKO-TEX® conform
Check with HeiQ which product can be utilized in
your target market

66
Differentiate.
Innovate.
HeiQ Switzerland HeiQ Australia HeiQ China HeiQ Portugal
HeiQ Materials AG HeiQ Australia Pty. Ltd. HeiQ Materials Company Limited c/o Idvance Consulting, LDA
Ruetistrasse 12 P.O. Box 940 Shanghai Rua Dr.Joaquim Nogueira dos
8952 Schlieren (Zurich) Geelong VIC 3220 Room 2011, Xuhui Commercial Santos, nº852, 5
Switzerland Australia Mansion, No. 168 Yude Road, 4475-474 Maia
Shanghai Portugal
Phone: +41 56 250 68 50 China
Fax: +41 56 250 68 41
[email protected] HeiQ Taiwan HeiQ USA
HeiQ Company Limited HeiQ ChemTex Inc.
No. 14, Ln. 50, Wufu 1st Rd. P.O. Box 5228
Luzhu District Concord, NC 28027
Taoyuan City 33850 USA
www.heiq.com Taiwan (R.O.C.)

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