Care of Clients With Problems in Cellular Aberrations Key Terms
Care of Clients With Problems in Cellular Aberrations Key Terms
Key Terms
anaplasia: cells that lack normal cellular characteristics and differ in shape andorganization with
respect to their cells of origin; usually, anaplastic cells are malignant.
cancer: a disease process whereby cells proliferate abnormally, ignoring growth regulating
signals in the environment surrounding the cells
chemotherapy: use of drugs to kill tumor cells by interfering with cellular functions and
reproduction
cytokines: substances produced by cells of the immune system to enhance production and
functioning of components of the immune system
dysplasia: bizarre cell growth resulting in cells that differ in size, shape, or arrangement from
other cells of the same type of tissue
extravasation: leakage of medication from the veins into the subcutaneous tissues
grading: identification of the type of tissue from which the tumor originated and the degree to
which the tumor cells retain the functional and structural characteristics of the tissue of origin
hyperplasia: increase in the number of cells of a tissue; most often associated with periods of
rapid body growth
metaplasia: conversion of one type of mature cell into another type of cell
metastasis: spread of cancer cells from the primary tumor to distant sites
nadir: lowest point of white blood cell depression after therapy that has toxic effects on the bone
marrow
radiation therapy: use of ionizing radiation to interrupt the growth of malignant cells
stomatitis: inflammation of the oral tissues, often associated with some chemotherapeutic
agents
thrombocytopenia: decrease in the number of circulating platelets; associated with the potential
for bleeding
tumor-specific antigen (TSA): protein on the membrane of cancer cells that distinguishes the
malignant cell from a benign cell of the same tissue type
vesicant: substance that can cause tissue necrosis and damage, particularly when extravasated
xerostomia: dry oral cavity resulting from decreased function of salivary glands