MDMA Facilitation
MDMA Facilitation
3-4 Methylenedioxymethamphetamine
This medicine works by helping you trust yourself and helping you accept parts
of yourself. It provides a feeling of safety and peacefulness that allows you to
revisit past experiences and aspects of yourself.
PTSD
Depression
Anxiety
Relationship satisfaction
Couples therapy
General personal growth and life enjoyment
Therapeutic introspection
Heightened self-esteem
Openness and self-forgiveness
Heightened empathy and sociability
Increased energy “The Empathogenic effect of the
Enhanced tactile, visual and auditory senses substance facilitates an emotional
understanding of the self and
emotions” David E. Nichols
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Pharmacology:
MDMA causes a release of serotonin as well as other neurotransmitters, like dopamine and
norepinephrine. It also causes increased levels of various hormones, including oxytocin that
helps humans experience others in a less negative way.
MDMA also decreases activity in the amygdala, the fear center. And it increases activity in the
prefrontal cortex, which is the higher processing center. This medicine has the ability to
decrease activity in the brain’s limbic system and reduce communication between the
temporal lobe and prefrontal cortex, both of which are involved in emotional control and
response.
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The Experience
• The MDMA assisted session takes place in a quiet and safe environment. It lasts up
to 3 hours.
• The person will feel somatic and emotional reactions. These feelings will not
necessarily be positive or negative. This is the stage at which the memories are
processed. It occurs internally, with the facilitator there to guide the individuals if
they need to talk or takes notes.