An Overview of Mixed Methods Research - Revisited: Louise Doyle
An Overview of Mixed Methods Research - Revisited: Louise Doyle
Louise Doyle
Assistant Professor, School of Nursing and Midwifery, Trinity College Dublin, Ireland
Anne-Marie Brady
Associate Professor, School of Nursing and Midwifery, Trinity College Dublin, Ireland.
Gobnait Byrne
Assistant Professor, School of Nursing and Midwifery, Trinity College Dublin, Ireland.
Abstract
Mixed methods have become increasingly popular in health-related research, allowing a broader
and deeper understanding of complex human phenomena. This growth in popularity has increased
the range of usage and complexity in design approaches, producing greater need for understanding
of logistical and practical application in this field. This paper aims to provide an overview of mixed
methods research and orientate readers to the critical issues that arise for researchers. It provides
an introduction to mixed methods design and the rationale and philosophical underpinnings for this
methodological approach. It navigates the reader through some real world or ‘hot’ topics within
mixed methods, including data analysis, integration and quality appraisal criteria.
Keywords
healthcare research, integration, mixed methods, qualitative research, quantitative research
Introduction
The landscape of mixed methods research has advanced significantly in the years since the
publication of our original ‘overview of mixed methods research’ (Doyle et al., 2009). Its
popularity as a research design has continued to grow, particularly in the fields of nursing
and health sciences (Creswell, 2015a) where it is commonly used as a design for graduate
theses and evaluation research. Concomitant with the increased use of mixed methods is an
exponential increase in the amount of instructional texts guiding novice and experienced
researchers alike (Creswell, 2015a; Sandelowski, 2014). This paper aims to provide an
overview of the current state of mixed methods research with a focus on a number
Corresponding author:
Louise Doyle, School of Nursing and Midwifery, Trinity College Dublin, 24 D’Olier St, Dublin 2, Ireland.
Email: [email protected]
624 Journal of Research in Nursing 21(8)
of critical issues. There continues to be significant debate about what constitutes mixed
methods research (Hesse-Biber, 2015); we are guided by the definition of Creswell (2015a),
who suggests that mixed methods research is an approach in which the researcher collects,
analyses and interprets both quantitative and qualitative data, integrates the two approaches
in various ways and frames the study within a specific design.
Triangulation Using quantitative and qualitative methods so that findings may be mutually
(convergence): corroborated.
This may also be an unanticipated outcome of the study where a mixed
methods study was undertaken for another reason, but convergence was
evident.
Expansion: The first phase has findings that require explanation qualitatively.
Unexpected findings that need to be explained.
Exploration: An initial phase is required to develop an instrument or intervention,
identify variables to study or develop a hypothesis that requires testing.
Completeness: Provides a more comprehensive account of phenomena under study.
Offset weaknesses: Ensures that weaknesses of each method are minimised (Creswell, 2015a).
Caution is required when identifying this as a primary rationale as each
method should be sufficiently rigorous in its own right (O’Cathain, 2010).
Different research Both quantitative and qualitative questions may be posed at the beginning of
questions: the study in addition to mixed methods questions (Creswell, 2015b).
Illustration: Qualitative data are used to illuminate quantitative findings.
Putting ‘meat on the bones’ of dry quantitative data (Bryman, (2006).
Doyle et al. 625
Philosophical underpinnings
Paradigms can be viewed as a system of beliefs and practices that influence how researchers
select both the questions they study and the methods they use to study them (Morgan, 2007).
The ‘paradigm wars’, which centred on the perceived differences in philosophical assumptions
between the positivist/post-positivist paradigms and the constructivist/interpretivist
paradigms, raged from the 1970s to the 1990s (Teddlie and Tashakkori, 2003). This war
fuelled the ‘incompatibility thesis’, the belief that the two paradigms could never be mixed
due to the inherent differences underlying them. It is beyond the scope of this paper to provide
an in-depth discussion of the paradigm wars; readers are directed elsewhere (Howe, 1988;
Morgan, 2007; Sale et al., 2002; Teddlie and Tashakkori, 2003). However, the incompatibility
thesis does pose a challenge – how can researchers mix methods when the paradigms on which
they are based have vastly difference ontological, epistemological and methodological
assumptions? For some, the adoption of a dialectical approach which advocates using two
or more paradigms together (Shannon-Baker, 2015) provides a solution to this issue. For
most, however, the answer is to adopt an alternative paradigm, that embraces a plurality of
assumptions and methods (Greene, 2007). Critical realism is one such paradigm which
supports the belief that quantitative and qualitative research can work together to address
the other’s limitations (Shannon-Baker, 2015) and offers strategies for mixed methods
researchers to better understand the context of what they study (Maxwell and Mittapalli,
2010). Other approaches include the transformative paradigm, which is a framework of belief
systems that places priority on social justice and human rights (Mertens, 2010) and the
incorporation of value-based goals within a mixed methods study (Shannon-Baker, 2015).
Pragmatism, however, is the most frequently identified alternative paradigm on which
mixed methods researchers base their work (Feilzer, 2010). The utility of pragmatism is that
it aims to find middle ground between philosophical dogmatisms (Johnson and Onwuegbuzie,
2004). On a practical level, pragmatism offers health researchers the freedom to choose the best
methods to answer the research question to hand (Bishop, 2015a), advocating for a balance
between subjectivity and objectivity throughout the research (Shannon-Baker, 2015). On a
philosophical level, pragmatism supports the view that while qualitative and quantitative
methods are distinct, they are also commensurate as both advance knowledge production
(Bishop, 2015a) and shared meaning making (Shannon-Baker, 2015).
overarching research question and is used primarily, although not exclusively, when
researchers are looking for convergence affording a more complete understanding of
phenomena (Doyle, 2015). Within this design, quantitative and qualitative data are
collected concurrently but remain separate – the findings of one phase are not dependent
on the results of another (Creswell and Plano Clark, 2011). In most convergent designs,
equal priority is assigned to quantitative and qualitative data and results are usually merged
in the interpretation phase of the research where meta-inferences are developed. It is an
efficient design as all data are gathered around the same time so the population remains
accessible. This is particularly beneficial in nursing and healthcare research where the sample
(frequently patients) may be discharged, thereby making a second phase of recruitment
difficult. One of the main challenges of a convergent design is deciding what to do if,
instead of converging, the findings actually diverge. Novice researchers in particular often
express a desire for convergence in their study in the hope of tying all the results up neatly
and strengthening the validity of their findings. However, as discussed later in this paper, it is
important to note that divergence is not necessarily a sign that something is wrong with the
study (O’Cathain et al., 2010). Stoddart et al. (2014) utilised a convergent (concurrent)
design to explore the new clinical leadership role of senior charge nurses. Quantitative
data were collected from 50 participants through the use of an online survey, and
nine participants took part in qualitative interviews to explore the views and
experiences of senior nurses regarding the implementation of a national clinical leadership
policy. This design provided a depth of responses that would not have been achievable with
the sole use of quantitative methods, with the additional benefit of a good degree of
convergence between quantitative and qualitative responses, thereby increasing the
validity of the study.
straightforward with distinct sequential phases of data collection making it possible for a
lone researcher to complete (Creswell and Plano Clark, 2011). Challenges include the fact
that because it is generally an emergent design where the second phase cannot be fully
developed until the first phase has been completed, the study may have to go before an
ethics committee or institutional review board (IRB) for a second time to gain approval for
the qualitative phase (Creswell and Plano Clark, 2011). Furthermore, the longer timeframe
required to undertake the study may make recruitment for the qualitative phase problematic
as the sample may no longer be available to the researcher. An explanatory sequential design
was used by Jellesmark et al. (2012) to explore fear of falling (FOF) and functioning ability
among older people following a hip fracture. In the first phase, surveys were used to identify
FOF and related factors. This was followed up by qualitative interviews with a sub-group of
participants who were identified from survey data as having a high degree of FOF. The
qualitative data allowed for an in-depth explanation of what influenced participants’ fear of
falling and how this impacted on their life.
Data analysis
Most mixed methods studies separately analyse quantitative and qualitative data with
methods suitable to their own tradition, merging the findings in the interpretation phase
(Creswell and Plano Clark, 2011). However, there is potential to further integrate data
analysis in mixed methods research using a number of techniques.
Typology development. Analysis of one method provides a framework for analysis of the
second; in most cases, quantitative data provide a framework to ‘hang’ qualitative data
on. A coding matrix is developed which identifies the main quantitative findings with a
text box underneath for the explanatory qualitative data. The qualitative data are then
630 Journal of Research in Nursing 21(8)
usually subjected to another level of thematic analysis. This method is particularly useful in
sequential explanatory designs as it helps to ensure that questions raised in the quantitative
phase are answered. However, it is important not to ignore other qualitative data, which
may not be directly linked to the quantitative data but may nonetheless provide valuable
insights.
Data transformation. Here one form of data is transformed into another. It can take the form
of qualitising data, where quantitative data are transformed into qualitative data. This is not
a frequently used method and usually involves constructing narrative profiles from
quantitative data. The most common form of data transformation occurs when
qualitative data are transformed into quantitative data (quantitising). This can occur
when qualitative data are assigned a binary value and are then analysed statistically
(Collingridge, 2013). Quantitising can also take the form of ‘counting’, where responses of
participants to various questions are counted. This generates descriptive statistics, which
allows for the identification of patterns in the data that may have been missed through
qualitative analysis (Collingridge, 2013). However, there is a note of caution with the use
of quantitising: qualitative data by their nature are not randomly selected or normally
distributed so caution is required when interpreting statistical tests and the generalisability
of the results (Maxwell, 2010). Furthermore, there is a real danger that the very essence of
qualitative research (production of rich, depth data) will be lost through this method, so
quantitisation should not replace qualitative analysis.
Software programs. Programs such as NVivo and MAXQDA can incorporate quantitative
data into a qualitative analysis. They can also facilitate the linking of demographic detail or
responses on a survey to qualitative data from individual cases (Bazeley, 2012), thereby
facilitating further integration of data.
Integration
Data integration has become a ‘hot topic’ in mixed methods research and is one of the major
issues facing those using these designs (Creswell, 2015b). Although much of the literature
refers to integration as the mixing of qualitative and quantitative data, it is broader than that
and can be defined as the bringing together of quantitative and qualitative components of a
study (O’Cathain et al., 2010). It is essentially the point(s) where quantitative and qualitative
phases intersect – it is the ‘mixing’ in a mixed methods study. Bryman (2007) suggests that
those reading mixed methods research deserve more from the findings than being presented
with parallel accounts that barely connect. Good integration in a mixed methods study
should provide ‘a whole greater than the sum of its parts’.
In a move away from the notion that integration in mixed methods research refers only to
data integration, Fetters et al. (2013) have identified how it can occur at the design, methods
and reporting/interpretation levels of research.
Integration at design level. An overlooked point of integration in mixed methods studies is the
setting of qualitative and quantitative questions within one study and/or the setting of
research questions that are inherently mixed methods from the outset (Creswell, 2015b).
Research questions that require both quantitative and qualitative methodologies to
answer them necessitate a mixed methods design – the development of which is a second
Doyle et al. 631
point of integration in mixed methods studies. The research design of a mixed methods study
should have at least one connecting point of integration and may have more. In the
explanatory and exploratory designs, one phase feeds directly into another. In convergent
designs, the two forms of data are directly compared.
Integration at methods level. At the methods level there may be several points of integration,
particularly in studies using a sequential design. Findings from the first phase may inform
development of a sampling frame for the second. This may occur in an explanatory design
where the qualitative sample is purposively selected to followup unusual results. Integration
can also occur when findings from the first phase are used to inform the development of the
second phase, termed integration – though building by Fetters et al. (2013). In an
exploratory study, findings from interviews may be used to develop an instrument that is
then tested quantitatively in phase two. In an explanatory study, findings from the
quantitative phase can inform the development of the interview guide and other data
collection tools such as vignettes to help inform the qualitative phase. The final point of
integration at the methods phase is at data analysis level as previously discussed.
Integration at discussion level. At the very least, a mixed methods study must be integrated at
discussion level (Creswell and Plano-Clark, 2011). Within the discussion section, inferences
may be drawn from each phase of the study separately. A crucial step forward is to then
develop meta-inferences, which are integrated understandings derived from both the
quantitative and qualitative data (Tashakkori and Teddlie, 2008). Meta-inferences go
beyond what is learned from the quantitative and qualitative components in isolation;
they provide a sense of the overall findings. In essence, the meta-inference(s) should
answer the mixed methods questions.
that high quality quantitative and qualitative components are necessary but not sufficient for a
quality mixed methods study (Tashakkori and Teddlie, 2008), a number of mixed methods
quality frameworks have been advanced; however, there are no agreed criteria for evaluating
mixed methods studies (Ivankova, 2014). In a bid to advance the ‘quality’ argument, O’Cathain
(2010) developed an eight-domain quality framework focusing on important components
including planning quality, design quality and reporting quality. This quality framework can
be a useful tool to determine quality. However, there are two caveats: first O’Cathain herself
recognises that in practice, this framework has too many criteria and that there is a need to
prioritise the most important elements; and second, quality frameworks should not be viewed
as rigid templates, but rather as general guidelines for use (Creswell, 2015b).
Conclusion
The use of mixed methods research continues to grow, and as a design it has much to offer
nursing and healthcare researchers. Its appeal is largely grounded in its ability to offer a
broader and deeper understanding of complex health circumstances and human phenomena
and in its ability to incorporate ‘the patient’s voice’ (Morse, 2015). This is evident in some of
the examples of mixed methods designs presented in this paper in which patients’ experiences
were qualitatively elucidated to explain results in more detail, making them more meaningful
to healthcare practitioners. To date, there have been limited texts providing an overview
Doyle et al. 633
of mixed methods research for those considering its use in healthcare research. The focus
instead has been on specific issues within mixed methods, including the paradigm wars and
the issue of data integration. This paper provides a sound starting point for novice researchers
and more experienced researchers unfamiliar with mixed methods designs by identifying key
issues and potential challenges in the use of this design. We hope that this paper encourages
healthcare researchers to undertake mixed methods studies, successful application of which
will be characterised by wisely selected research designs and careful diligence in planning and
addressing issues such as integration, analysis and quality appraisal.
Funding
The author(s) received no financial support for the research, authorship and/or publication of this
article.
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Doyle et al. 635
Louise Doyle (PhD, MSc, BNS, RPN, RNT) is an Assistant Professor in mental health
nursing at the School of Nursing and Midwifery, Trinity College Dublin. She has
experience using a range of mixed methods, designs primarily within the area of mental
health focusing on topics including self-harm in young people, adolescent help-seeking and
the mental health of lesbian, gay, bisexual, trans and/or intersex (LGBTI) people. She has
led mixed methods projects which evaluated innovative mental health interventions
including wellness interventions for the general population. She delivers workshops for
PhD students and early career researchers on mixed methods research and has published
mixed methods studies.
Anne-Marie Brady (PhD, MSc, DSN, Pg Dip Stats, Pg Dip CHSE, RGN, RNT) is Director
of the Centre for Practice & Healthcare Innovation in Trinity College Dublin. She is an
experienced mixed methods researcher in the field of healthcare systems, evaluation and
quality improvement. She has employed a range of mixed method studies in collaboration
with health service providers to examine real world issues around health service delivery,
integration of care, system- and patient-related outcomes, safety, workload and competency
among healthcare workers.
Gobnait Byrne (MPH, Pg Dip Stats, BNS, RGN, RNT) is an Assistant Professor in general
nursing in the School of Nursing and Midwifery, Trinity College Dublin. She has recently
completed a mixed methods study exploring the health, lifestyles and use of health services
by Polish migrants living in Ireland.