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Mechanism of Action: Calendula Officinalls

Calendula officinalis has been shown to promote wound healing through several mechanisms. It may stimulate epithelial cell growth and enhance immune responses, reducing wound healing time. Calendula also has potent anti-inflammatory properties, inhibiting proinflammatory cytokines and Cox-2 to decrease prostaglandin synthesis. While calendula is generally safe, pregnant women should avoid internal or topical use due to a potential risk of miscarriage. People on medications should check for drug interactions before using calendula.

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Abdelrhman Abooda
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41 views1 page

Mechanism of Action: Calendula Officinalls

Calendula officinalis has been shown to promote wound healing through several mechanisms. It may stimulate epithelial cell growth and enhance immune responses, reducing wound healing time. Calendula also has potent anti-inflammatory properties, inhibiting proinflammatory cytokines and Cox-2 to decrease prostaglandin synthesis. While calendula is generally safe, pregnant women should avoid internal or topical use due to a potential risk of miscarriage. People on medications should check for drug interactions before using calendula.

Uploaded by

Abdelrhman Abooda
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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: dried flower of calendula officinalis family Mechanism of action

compositea
• Wound healing effects: it has been proposed that
Calendula officinalls extract may aid in wound healing
by promoting epithelial growth and by enhancing
immune responses. Rao et al observed a reduction of
active constituents epithelialization time, an increase in wound strength.
And improvement of wound contraction in rates with
• : Lupeol, Erythrodiol, experimential incision wounds that were topically
• Calenduloside, Calendulaglycoside treated with calendula.
• The results showed that potent anti-inflammatory
A, Calendulaglyoside B, Cornulacic acid aetate. response of C. officinalis extract may be mediated by Calendula is also called marigold and
inhibition of proinflammatory cytokines and Cox-2 and pot marigold, leading to confusion with
• : Isoquercitrin, Rutin, Calendoflavoside,
subsequent prostaglandin synthesis. members of the genus Tagetes, which
Quercetin, Isorhamnetin, Narcissin. go by the same common name
• : Esculetin, Scopoletin, Umbelliferone.
• : Cubenol, Oplopanone, Methyllnoleate, C.I
Sabinene, Limonene, p-cymene, Nonanal, Carvacrol, • Pregnant women: it is not proven the safety of this
Prepared by
Geraniol, Nerolidol, t-muurolol, Palustron. plant during pregnancy, it may cause miscarriage • Amira halmy
and should not be used internally or externally • Amal yahia
• People with an allergy to compositea plant • Kholoud yaser
Uses • Durgs and operations: people who are in drug • Sama yaser
• Soothing: Soother & Decreases the pain. treatment or an operation should not use this
• Shrouk bahaa
• Reduce inflammation: works well on sprains, Muscles or plant. There are insufficient studies on the effect of
Bruises. the plant with other drugs or emdications. • Shimaa khalad
• Anti-inflammatory Activity Helps decrease swelling from • The first notes indicate that Calendula may
injury. increase the effect of sedatives sleeping pills.
• Helps treat spider veins, varicose veins, leg ulcers &
chilblains.
• Infant care: helps diaper rashes.
• Cuts & wounds: Antimicrobial & Antiseptic action helps Supervised by
accelerate Healing & Benefit bed sores, Acne, Insect bites. SIDE effects
• skin issue: Great for Eczema, Dermatitis, Psoriasis & • An allergic reaction to this product is unlikely . Symptoms of an Dr. Adel Abd-Elkader
Other skin problems. allergic reaction include: rash, itching, swelling, dizziness,
• The antifungal activity can be great for treating jick itch, trouble breathing.
Ringworm, Athlete's Foot.

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