Sexually Transmitted Diseases: Nelia B. Perez RN, MSN Class 2015
Sexually Transmitted Diseases: Nelia B. Perez RN, MSN Class 2015
TRANSMITTED
DISEASES
Class 2015
Sexually Transmitted Diseases
• Infectious diseases most commonly transmitted
through sexual contact
• Can also be transmitted by
• Blood
• Blood products
• Autoinoculation
National Health Picture on STDs
• As of January 2013, the Department of
Health (DOH) AIDS Registry in the
Philippines reported 10,514 people living
with HIV/AIDS.
• Most Common in the Philippines
- Chlamydia
- Gonorrhea
- Genital Herpes
- HIV / AIDS
- Syphillis
- Ectoparasitic Infections
General Overview
• Highest incidence: adolescents &
young adults
• Sexual abuse
• Primary Prevention
• Advocate for adolescent education
re: sex and sexually transmitted
disease. (AAP, 2001)
• Abstinence
• Condoms
4
Healthy People 2020
• Goal: Promote healthy
sexual behaviors,
strengthen community
capacity, and increase
access to quality
services to prevent
sexually transmitted
diseases and their
complications.
5
Factors contributing to spread
• Asymptomatic nature of STDs
• Gender disparities
• Age disparities
• Lag time between infection and
complications
• Social, economic and behavioral factors
6
Risk Factors
• IV drug use
• Other substance abuse
• High-risk sexual activity
• Younger age at beginning of sexual activity
• Inner city residence
• Poverty/lower socioeconomic status
• Poor nutrition
• Poor hygiene
7
• SterilityConsequences
• Neurologic damage
• Ophthalmic infection – other
congenital problems for
newborn
• Cancer
• Death
8
Unwanted Pregnancy
9
Gonorrhea
Etiology and Pathophysiology
• 2nd most frequently reported STD in US
• Caused by Neisseria gonorrheae
• Gram-negative bacteria
• Direct physical contact with infected host
• Killed by drying, heating, or washing with
antiseptic
• Incubation: 3-8 days
Gonorrhea
Etiology and Pathophysiology
• Elicits inflammatory process that can lead to fibrous
tissue and adhesions
• Can lead to :
• Tubal pregnancy
• Chronic pelvic pain
• Infertility in women
Gonorrhea
Clinical Manifestations
• Men
• Initial site of infection is urethra
• Symptoms
• Develop 2 to 5 days after infection
• Dysuria
• Profuse, purulent urethral discharge
• Unusual to be asymptomatic
Gonococcal Urethritis
Fig. 53-1
Gonorrhea
Clinical Manifestations
• Women
• Mostly asymptomatic or have minor symptoms
• Vaginal discharge
• Dysuria
• Frequency of urination
Gonorrhea
Clinical Manifestations
• Women (cont’d)
• After incubation
• Redness and swelling occur at site of contact
• Greenish, yellow purulent exudate often develops
• May develop abscess
Fig. 53-2
Gonorrhea
Clinical Manifestations
• Anorectal gonorrhea
• Usually from anal intercourse
• Soreness, itching, and anal discharge
• Orogenital
• Gonoccocal pharyngitis can develop
Gonorrhea
Complications
• Men
• Include prostatitis, urethral strictures, and sterility
• Often seek treatment early so less likely to
develop complications
Gonorrhea
Complications
• Women
• Include pelvic inflammatory disease (PID),
Bartholin’s abscess, ectopic pregnancy, and
infertility
• Usually asymptomatic so seldom seek treatment
until complication are present
Gonorrhea
Diagnostic Studies
• History and physical examination
• Laboratory tests
• Gram-stained smear to identify organism
• Culture of discharge
• Nucleic acid amplification test
• Testing for other STDs
Gonorrhea
Treatment & Nursing Care
• Drug therapy
• Treatment generally instituted without culture
results
• Treatment in early stage is curative
• Most common
• IM dose of ceftriaxone (Rocephin)
Gonorrhea
Treatment & Nursing Care cont’d
• All sexual contacts of patients must be evaluated
and treated
• Patient should be counseled to abstain from sexual
intercourse and alcohol during treatment
• Reexamine if symptoms persist after treatment
Syphilis
Syphilis
Etiology and Pathophysiology
• Caused by Treponema pallidum
• Spirochete bacterium
• Enters the body through breaks in skin or
mucous membranes
• Destroyed by drying, heating or washing
• May also spread via contact with lesions and
sharing of needles
Syphilis
Etiology and Pathophysiology
• Incubation 10 to 90 days
• Spread in utero after 10th week of pregnancy
• Infected mother has a greater risk of a stillbirth or
having a baby who dies shortly after birth
Syphilis
Etiology and Pathophysiology
Fig. 53-4
Syphilis
Clinical Manifestations
• Secondary stage
• Systemic
• Begins a few weeks after chancres
• Blood-borne bacteria spread to all major organ systems
• Flu-like symptoms
• Bilateral symmetric rash
• Mucous patches
• Condylomata lata
Secondary Syphilis
Fig. 53-5
Syphilis
Clinical Manifestations
• Latent or hidden stage
• Immune system is suppressing infection
• No signs/symptoms at this time
• Diagnosed by positive specific treponema
antibody test for syphilis with normal
cerebrospinal fluid
Syphilis
Clinical Manifestations
• Tertiary or late stage
• Manifestations rare
• Significant morbidity/mortality rates
• Gummas
• Cardiovascular system
• Neurosyphilis
Syphilis
Complications
• Occur mostly in late syphilis
• Irreparable damage to bone, liver, or skin from
gummas
• Pain from pressure on structures such as
intercostal nerves by aneurysms
Syphilis
Complications
• Scarring of aortic valve
• Neurosyphilis
• Tabes dorsalis
• Sudden attacks of pain
• Loss of vision and sense of position
Syphilis
Diagnostic Studies
• History including sexual history
• PE
• Examine lesions
• Note signs/symptoms
• Dark-field microscopy
• Serologic testing
• Testing for other STDs
Syphilis
Treatment & Nursing Care
• Drug therapy
• Benzathine penicillin G (Bicillin)
• Aqueous procaine penicillin G
Syphilis
Treatment & Nursing Care cont’d
• Monitor neurosyphilis
• Confidential counseling and HIV testing
• Case finding
• Surveillance
Chlamydial Infections
Etiology and Pathophysiology
• #1 reported STD in US
• Caused by Chlamydia trachomatis
• Gram-negative bacteria
• Transmitted during vaginal, anal, or oral sex
• Incubation period: 1 to 3 weeks
Chlamydial Infections
Etiology and Pathophysiology
• Risk factors
• Women and adolescents
• New or multiple sexual partners
• History of STDs and cervical ectopy
• Coexisting STDs
• Inconsistent/incorrect use of condoms
Chlamydial Infections
Clinical Manifestations
• “Silent disease”
• Symptoms may be absent or minor
• Infection often not diagnosed until complications
appear
Chlamydial Infections
Clinical Manifestations
• Men
• Urethritis
• Dysuria
• Urethral discharge
• Proctitis
• Rectal discharge
• Pain during defecation
Chlamydial Infections
Clinical Manifestations
• Men (cont’d)
• Epididymitis
• Unilateral scrotal pain
• Swelling
• Tenderness
• Fever
• Possible infertility and reactive arthritis
Chlamydial Infection
Fig. 53-6
Chlamydial Infections
Clinical Manifestations
• Women
• Cervicitis
• Mucopurulent discharge
• Hypertrophic ectopy
• Urethritis
• Dysuria
• Frequent urination
• Pyuria
Chlamydial Infections
Clinical Manifestations
• Women (cont’d)
• Bartholinitis
• Purulent exudate
• Perihepatitis
• Fever, nausea, vomiting, right upper quadrant
pain
Chlamydial Infections
Clinical Manifestations
• Women (cont’d)
• PID
• Abdominal pain, nausea, vomiting, fever,
malaise, abnormal vaginal bleeding,
menstrual abnormalities
• Can lead to chronic pain and infertility
Chlamydial Infections
Diagnostic Studies
• Laboratory tests
• Nucleic acid amplification test (NAAT)
• Direct fluorescent antibody (DFA)
• Enzyme immunoassay (EIA)
• Testing for other STDs
• Culture for chlamydia
Chlamydial Infections
Treatment & Nursing Care
• Drug therapy
• Doxycycline (Vibramycin)
• 100 mg BID for 7 days
• Azithromycin (Zithromax)
• 1 g in single dose
• Alternatives include erythromycin, ofloxacin
(Floxin), or levofloxacin (Levaquin)
Chlamydial Infections
Treatment & Nursing Care cont’d
• Abstinence from sexual intercourse for 7 days after
treatment
• Follow-up care for persistent symptoms
• Treatment of partners
• Encourage use of condoms
Chlamydia
• Prevention: limit the number of sexual partner & use
condoms & spermicides
Fig. 53-8
Genital Herpes
Diagnostic Studies
• History and physical examination
• Viral isolation by tissue culture
• Antibody assay for specific HSV viral type
Genital Herpes
Treatment & Nursing Care
• Drug therapy
• Inhibit viral replication
• Suppress frequent recurrences
• Acyclovir (Zovirax)
• Valacyclovir (Valtrex)
• Famciclovir (Famvir)
• Not a cure but shorten duration, healing time and
reduce outbreaks
Genital Herpes
Treatment & Nursing Care cont’d
• Symptomatic care
• Genital hygiene
• Loose-fitting cotton underwear
• Lesions clean and dry
• Sitz baths
• Barrier methods during sexual activity
• Drying agents
• Pain: dilute urine with water, local anesthetic
Genital Herpes
• Treatment: use Betadine on lesions to dry &
prevent secondary infections, however,
Acyclovir (Zovirax) eases symptoms &
lessens reoccurrence but is not a cure
• If Untreated: in fetus/newborns there is a risk
of spontaneous abortion; neonatal herpes;
mental retardation, death
• Prevention: limit number of sexual partners
and using condoms & spermicidal foam may
reduce transmission
Nursing Implications?
Genital Warts
• Most common STD in the US
• Often asymtomatic so patient maybe unaware of
infection
• Caused by human papillomavirus (HPV)
• Usually types 6 and 11
• Highly contagious
• Frequently seen in young, sexually active adults
Genital Warts
Etiology and Pathophysiology
• Minor trauma causes abrasions for HPV to enter
and proliferate into warts
• Epithelial cells infected undergo transformation and
proliferation to form a warty growth
• Incubation period 3 to 4 months
Genital Warts
Clinical Manifestations
• Discrete single or multiple growths
• White to gray and pink-fleshed colored
• May form large cauliflower-like masses
Genital Warts
Clinical Manifestations
• Warts in men: penis, scrotum, around anus, in
urethra
• Warts in women: vulva, vagina, cervix
• Can have itching with anogenital warts & bleeding
on defecation with anal warts
Genital Warts
Diagnostic Studies
• Serologic and cytologic tests
• HPV DNA test to determine if women with
abnormal Pap test results need follow-up
• Identify women who are infected with high-risk
HPV strains
Genital Warts
Diagnostic Studies
• Primary goal: Removal of symptomatic warts
• Removal may or may not decrease infectivity
• Difficult to treat
• Often require multiple office visits and variety of
treatment modalities
Genital Warts
Treatment & Nursing Care
• Chemical
• Trichloroacetic acid (TCA)
• Bichloroacetic acid (BCA)
• Podophyllin resin
• For small external genital warts
• Patient managed
• Podofilox (Condylox.Condylox gel0
• Imiquimod (Aldara)
• Immune response modifier
Genital Warts
Treatment & Nursing cont’d