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Fentanyl Citrate Drug Study

Fentanyl citrate is a potent opioid analgesic that increases pain threshold and inhibits ascending pain pathways in the central nervous system. It is used as an adjunct to general anesthesia in adults. Common side effects include reduced pulmonary compliance, nausea, vomiting, bradycardia, central nervous system depression, and hypotension. It should not be used in opioid non-tolerant patients, acute or severe respiratory depression, or paralytic ileus. Nurses must monitor vital signs, respiratory status, and therapeutic response when administering fentanyl citrate.

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Arthur Christopher Corpuz
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953 views

Fentanyl Citrate Drug Study

Fentanyl citrate is a potent opioid analgesic that increases pain threshold and inhibits ascending pain pathways in the central nervous system. It is used as an adjunct to general anesthesia in adults. Common side effects include reduced pulmonary compliance, nausea, vomiting, bradycardia, central nervous system depression, and hypotension. It should not be used in opioid non-tolerant patients, acute or severe respiratory depression, or paralytic ileus. Nurses must monitor vital signs, respiratory status, and therapeutic response when administering fentanyl citrate.

Uploaded by

Arthur Christopher Corpuz
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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REPUBLIC of the PHILIPPINES

City of Makati
COLLEGE OF ALLIED HEALTH STUDIES
J. P. Rizal Extension, West Rembo, Makati City 1215
Telephone No. : (+632) – 881 – 1571
_____________________________________________________________________________________
DRUG STUDY
Drug Name Mechanism of Action Indication Side Effects/Adverse Contraindication Nursing Consideration
Effect
Generic Name: Fentanyl is a potent opioid Adjunct to General Reduce pulmonary Opioid nontolerant patient. - Assess the 12 Rights in Giving Medication
Fentanyl Citrate analgesic that increases pain Anesthesia compliance and/or Treatment of acute pain
Brand Name: threshold, alters pain apnoea, other than breakthrough
Abstral reception and inhibits bronchoconstriction, pain (e.g. migraine or other - Special precautions, rapid IV infusion may cause skeletal
Dosage ascending pain pathways by laryngospasm; nausea, headaches) or post-op pain; muscle and chest wall rigidity. Prolonged use may cause
Intravenous binding to stereospecific vomiting; bradycardia, acute or severe resp tolerance, psychological and physical dependence. Abrupt
Adjunct to general anaesthesia receptors w/in the CNS. oedema, CNS depression, depression or obstructive withdrawal may lead to withdrawal symptoms, gradually taper
Adult: Patients w/ spontaneous confusion, dizziness, lung disease; paralytic ileus.. down the dose to avoid this risk.
respiration: Initially, 50-200 mcg followed drowsiness, headache,
by supplements of 50 mcg. Max: 200 sedation, hypotension, - Monitor body temp, heart rate, BP, resp & CV status.
mcg. Admin infusion rates of 0.05-0.08 Reference: peripheral vasodilation,
mcg/kg/min. Patients w/ assisted MIMS 151st Edition 2017 increased intracranial - Evaluate therapeutic response.
ventilation: Initially, 300-3,500 mcg (up to DRUG REFERENCE: pressure, itching, rash,
50 mcg/kg) followed by supplements of https://www.mims.com/ erythema, papules,
100-200 mcg depending on patient's pruritus, exfoliative
response. Loading dose (alternatively via dermatitis, pustules,
bolus): Approx 1 mcg/kg/min given for the macular rash; gum
1st 10 min followed by infusion of approx bleeding and irritation,
0.1 mcg/kg/min. taste perversion, dental
caries, tooth loss, gum
line erosion; throat
irritation, nasal ulcers,
epistaxis, rhinorrhoea;
coughing; urinary
retention.

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