Esco Service Guide
Esco Service Guide
2
Table of Contents:
Corporate Profile............................................................................. 3
Products and Application................................................................. 4
Global Network............................................................................... 4
Decontamination and Maintenance................................................. 5
Parts Replacement........................................................................... 5
Validation and Certification............................................................. 5
Descriptions of Esco Validation and Certification Services................. 6
IQ/OQ Documentation..................................................................... 6
Aftermarket Support....................................................................... 7
Training and Workshop................................................................... 7
Biological Safety Cabinets................................................................ 8
Compounding Pharmacy Equipment............................................... 9
Ductless Fume Hoods.................................................................... 10
Special Purpose Cabinets............................................................... 11
Laboratory Fume Hoods................................................................ 12
Lab Animal Research Products....................................................... 13
Laminar Flow Clean Benches......................................................... 14
Powder Weighing Balance Enclosures............................................ 15
Welcome to Esco
Esco’s Vision is to provide enabling technologies for scientific discoveries to make human lives
healthier and safer.
• A leader in the development of controlled environment, • Group total of more than 500 employees.
laboratory and cleanroom equipment solutions. • Distributors in more than 100 countries.
• A world leader in biological safety cabinets. • Products independently tested to international standards.
• Headquartered in Singapore. • Large R&D investments, world leading technologies.
• North American facilities in Pennsylvania and Ohio • State-of-the-art production, vertically integrated, 300,000
Sales, service, logistics for US & Canada. sq. ft. floor space.
• Other Esco locations in Bahrain, China, India, Malaysia, • Worldwide service.
Netherlands, UK.
Pictured: Esco provides service worldwide via a network of highly trained factory direct and independent service representatives."
Products and Application
Laboratory Equipment
Biosafety and Fume Hoods Incubators and Life Science Cold Chain
Laminar Flow Ovens Storage
• Class II Type A2 • Ductless Fume • CO2 Incubators • PCR Thermal Cyclers • Ultra Low
Biological Safety Hoods Temperature Freezers
• Forced Convection
Cabinets
• Exhaust Blowers Laboratory Incubators
• Class II Type B2
• Fume Hood Airflow • Forced Convection
Biological Safety
Monitors Laboratory Ovens
Cabinets
• Fume Scrubbers • Low Temperature
• Class III Biological
BOD Incubators
Safety Cabinets • Laboratory Fume
Hoods • Natural Convection
• Horizontal Laminar
Laboratory Incubators
Flow Clean Benches
• Remote Monitoring,
• In Vitro Fertilization
Data Logging,
Workstations
and Programming
4 • Laboratory Animal Software
Research Workstations
• PCR Cabinets
• Vertical Laminar
Flow Clean Benches
Not Available in North America
Global Network
Proper operation of Esco products usually requires periodic maintenance and/or decontamination in accordance with common
Standard Operating Procedures and recognized laboratory safety protocols.
Decontamination is a process that reduces contaminants to acceptable levels in biological safety cabinets to eliminate their disease
causing capabilities. Decontamination/fumigation using formaldehyde, hydrogen peroxide or other agents should only be carried
out by trained personnel with proper knowledge and equipment.
Parts Replacement
Every Esco cabinet is manufactured as a commercial grade product and Esco provides replacements for consumable elements as
well as any components that might fail while the product is in service.
Every Esco product is shipped with a Statement of Part Numbers for Replaceable Parts. From time to time, Esco may use
components from different sources or change them after design improvements. The serial number of a product, usually located
on an identification tag on its upper front side, may be used to query an on-line database to retrieve accurate part numbers.
In order to maintain consistent and safe operating conditions for any equipment, regular performance tests must be conducted.
Esco’s Validation and Certification Services can ensure that all Esco equipment is providing sufficient containment in the equipment’s
work areas and a pleasant working environment for its operators.
Esco provides its customers with IQ/OQ documentation for its products and offers a broad range of validation, certification and
maintenance services to support their needs. Regular attention to equipment performance will ensure optimal performance and
early detection and correction of potential problems, thus increasing utilization and product yields.
Thoroughly trained, experienced and competent engineers perform clean room and associated clean air device certification in
accordance with NEBB procedural standards, IEST (Institute of Environmental Sciences) Recommended Practices, ISO 14664.1,
the NSF 49 Standard for Biosafety Cabinets, EN12469 European Norm Standard for Microbiological Safety Cabinets, and others.
We also offer customized certification audits and evaluation programs for clean rooms and associated clean air devices.
Esco and/or our officers are members of the following professional organizations:
Service Description
Airflow Balancing Adjust cabinet internal flow control devices to produce desired air flow.
ULPA / HEPA Filter Integrity Determine the integrity of down flow and exhaust filters by measuring penetration of a test aerosol.
ULPA / HEPA Filter Replacement Replace compromised filters or those at the end of their service life.
Inflow / Face Velocity Determine the velocity profile of air entering a cabinet through its work access opening via measurement and calculation.
Laminar Flow Velocity Determine the velocity profile of air moving within a cabinet work space using a thermal anemometer.
Particle Count Verify work zone air cleanliness in accordance with ISO 14644.1 classification criteria by particle counting.
Airflow Visualization Qualitatively evaluate airflow into work access area by visualizing smoke patterns.
Airflow Alarm Calibration Adjust the alarm set point of the airflow measurement system.
Blower / Fan Replacement Remove and replace a defective blower or fan assembly.
Electrical Troubleshooting Examine electrical devices, wiring connections and adjustments in a cabinet to diagnose and correct improper operation.
Electrical Safety Inspect grounding system and measure leakage currents in a cabinet electrical system to ensure equipment safety.
GFCI Performance Test Ground Fault Circuit Interrupter outlets, when installed, to ensure proper operation and protection.
Pressurization Measure pressure differentials from ambient in cabinet work space and/or pass-through to evaluate adequacy.
6 Enclosure Integrity Assess the integrity of the surfaces, seams and joint of a cabinet.
Product Ingress / Egress Measure particle counts during material transfer procedures into/out of glove boxes/isolators to verify acceptable values.
Recovery Time Measure the time interval after simulated major contamination for a cabinet work zone to return to acceptable cleanliness.
Glove Breach Verify the integrity of a glove and its attachment system to an isolator/glove box by measuring inward airflow at an open glove port.
Decontamination Biologically sterilize a cabinet using formalin vapor or hydrogen peroxide.
Noise Measure the corrected A-weighted sound level pressure produced by the fan(s).
Light Measure the lighting intensity at the work surface in a cabinet.
Vibration Measure vibration level of the work surface to prevent damage to sensitive processes and to ensure operator comfort.
UV Intensity Measure the effectiveness of the ultraviolet lamp, when installed, for surface germicidal decontamination.
Site Installation Assessment Verify proper installation of cabinet pursuant to recommended practices regarding location, external connections, etc.
KI Discus Containment Determine the containment integrity of a cabinet by measurement of potassium iodide droplet leakage.
SF6 Chemical Containment Determine the containment integrity of a cabinet by measurement of sulfur hexafluoride gas leakage.
Carbon Filter Retention Measure the adsorption capacity of a carbon filter to assess performance.
Carbon Filter Replacement Remove and replace compromised carbon filters or those at the end of their service life.
Aerosol Induction (Sash Seal) Inspect for leakage of the sash seal of a cabinet using an aerosol.
Temperature Calibration Sensor adjustment, temperature fluctuation, temperature uniformity and temperature recovery test.
CO2 Calibration Sensor adjustment, CO2 fluctuation and CO2 recovery test.
O2 Calibration Sensor adjustment, O2 fluctuation and O2 recovery test.
Humidity Calibration Sensor adjustment, humidity fluctuation and humidity recovery test.
Heater Replacement Remove and replace a defective heater assembly.
Pump Replacement Remove and replace a defective pump.
Piping Replacement Remove and replace compromised piping.
Compressor Replacement Remove and replace a defective compressor.
Thermostat Replacement Remove and replace the hard wired safety thermostat.
Pre-Filter Replacement Remove and replace compromised pre-filters filters or those at the end of their service life.
Lamp Replacement Remove and replace defective or underperforming cabinet fluorescent and/or ultraviolet lamp bulbs.
General Cleaning and Maintenance Thoroughly inspect, clean surfaces of, and make performance adjustments on a cabinet.
A certified process ensures that qualified equipment is used pursuant to validated Standard Operating Procedures (SOPs). Those
SOPs that are applicable to equipment and instruments are classified as follows:
Installation Qualification (IQ) documents that the specified equipment was received and properly installed in a suitable
environment. IQ is also required for used equipment installation, equipment moved within a facility or connected to modified
systems at the facility or subject to a changed SOP. IQ can be performed by the customer or Esco.
Operational Qualification (OQ) documents that the equipment still meets its specifications after installation in the customer’s
facility. OQ can be performed by the customer or Esco, and must be performed at least annually for every piece of equipment.
Esco provides our customers instructions for IQ and OQ of our products. Esco also can perform these services directly on behalf
of its customers or arrange them through independent approved local certifiers. The availability may vary from country to country
and region to region. Also, Esco can train customer employees to perform IQ/OQ as described in the Aftermarket Support section
later in this document.
Aftermarket Support
Extended Warranty
Extensions of Esco's standard warranty against defects in materials and workmanship are available. Extended warranties fix the
capital cost of ownership of the product over its entire service life by eliminating the risk of failure due to latent defects.
Replacement Manuals
All Esco products are shipped with comprehensive installation and operation documentation. While Esco Service Manuals include
information for field-level maintenance, electrical component replacement and calibration.
Esco offers training for users of its equipment on the procedures in its User and Service Manuals.
Operational training includes product placement, electrical connection, connection to facility air handling system, adjustment of
leveling feet and locking of casters, use of Sentinel Software and pressure measurement instrumentation, cleaning, decontamination
and changing filters.
Maintenance training includes the procedures used by our personnel and described above. You can assure that your personnel
are prepared to deploy and use your Esco products.
Certification training is similar in scope to the training described above, and includes hands on demonstration of the skills being
taught. The use of certified personnel facilitates assessing utilization, productivity and risks of complicated or sensitive protocols.
Those who complete Esco Certification Workshops will receive a certificate of attendance.
Biological Safety Cabinets
The Safety Solution for Life Science Laboratories
* Esco is a member of the NSF49 Joint Comittee that maintains the NSF49 standard
* Esco participated in drafting the SFDA YY-0569 standard
Product lines:
• General Purpose Benchtop Hoods.
• Acid Digestion Hoods.
• Perchloric Acid Hoods.
• Radioisotope Hoods.
• Floor Mounted Hoods.
• High Performance, Low Flow Hoods.
• Educational Hoods.
• Polypropylene Hoods.
• Chemical Fume Scrubbers.
• Exhaust Blowers.
• Ductless Fume Hoods.
Product lines:
• Powder Weighing Balance Enclosures.
Product lines:
• Ultra Low Temperature Freezers.
• CO2 Incubators.
• Forced Convection Laboratory Ovens.
• Forced Convection Laboratory Incubators.
• N a t u r a l C o n v e c t i o n L a b o r a t o r y
Incubators.
• Low Temperature BOD Incubators.
CO2
Testing/Maintenance Service Oven Incubators Freezers
Incubators
ULPA / HEPA Filter Replacement If Required
O2 Calibration Optional
Esco Technologies, Inc. • 2940 Turnpike Drive, Units 15-16 • Hatboro, PA 19040, USA
Toll-Free USA and Canada 877-479-3726 • Tel 215-441-9661 • Fax 215-441-9660
us.escoglobal.com • [email protected]
9010108_Esco_Service Guide_Brochure_A4_v.A1_04/11
Esco Micro Pte. Ltd. • 21 Changi South Street 1 • Singapore 486 777
Tel +65 6542 0833 • Fax +65 6542 6920 • [email protected]
www.escoglobal.com
Esco Global Offices | Beijing, China | Kuala Lumpur, Malaysia | Manama, Bahrain | Guangzhou, China |
Hanoi, Vietnam | Melaka, Malaysia | Mumbai, India | Philadelphia, PA, USA | Salisbury, UK | Shanghai, China | Seoul,
Korea | Delhi, India | Osaka, Japan | Manila, Philippines | Midrand, South Africa | Jakarta, Indonesia | Singapore
.
escoglobal com
LIVE SUPPORT Esco Micro Pte Ltd PT Esco Bintan Indonesia
Cert. No: 651076 Cert. No: 651333/E