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Medication: Expected Pharmacological Action Therapeutic Use

Naloxone is an opioid antagonist used to reverse the effects of opioid overdose, including respiratory depression and central nervous system depression. It works by competitively blocking opioid receptors without producing any agonist effects. Naloxone is administered via nasal spray, injection, or in combination with buprenorphine. It is important to monitor patients for changes in vital signs, consciousness level, and pain after administration due to the risk of precipitating opioid withdrawal.

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Marina Wasem Netzlaff
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280 views1 page

Medication: Expected Pharmacological Action Therapeutic Use

Naloxone is an opioid antagonist used to reverse the effects of opioid overdose, including respiratory depression and central nervous system depression. It works by competitively blocking opioid receptors without producing any agonist effects. Naloxone is administered via nasal spray, injection, or in combination with buprenorphine. It is important to monitor patients for changes in vital signs, consciousness level, and pain after administration due to the risk of precipitating opioid withdrawal.

Uploaded by

Marina Wasem Netzlaff
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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ACTIVE LEARNING TEMPLATE: Medication

k
STUDENT NAME______________________________________
Naloxone
MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER____________

CATEGORY CLASS__opioid antagonist / antidotes (for opioids)


_____________________________________________________________________

PURPOSE OF MEDICATION

Expected Pharmacological Action Therapeutic Use


Competitively blocks the effects of opioids, Reversal of signs of opiod excess.
including CNS and respiratory depression,
without producing any agonist effects.

Complications Medication Administration


Hypertension, hypotension, nausea, vomiting, ventricular Nasal spray: 4mg/0.1mL
arrythmias. Solution for injection: 0.4mg/mL,
2mg/0.4mL, 2mg/2mL, 4mg/
10mL
In Combination with:
buprenorphine (Suboxone,
Zubsol).
Contraindications/Precautions
Hypersensitivity
Contraindicated: cardiovascular disease, patients
physically dependend on opioids, may cause acute Nursing Interventions
withdrawal syndrome in neonates of opioid-dependent Monitor: RR, rhythm, and depth,
mothers. pulse, ECG, BP, LOC,
frequently for 3-4 hour after the
expected peak and blood
concentrations.
Interactions
Assess pain level after
Can precipitate withdrawal in patients physically administration of medication.
dependent on opioid analgesics. Larger doses may be
required to reverse the effects of buprenorphine,
butorphanol, or nalbuphine. Antagonizes postoperative
opioid analgesics. Client Education
Explain purpose and effects to
patient.
Evaluation of Medication Effectiveness Instranasal: instruct parents and
Adequate ventilation following opioid excess. Alertness caregiver in the correct
without significant pain or withdrawal symptoms. technique for use.
Evzio: advise to continue
monitoring patient after injection

ACTIVE LEARNING TEMPLATES

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