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Kami Export - Omarion Fladger - Pedigree Genetics Problems

1. The pedigree shows a family history of Huntington's disease. Affected individuals are I-1, II-2, II-3, II-7, and III-3. 2. Huntington's disease is caused by a dominant trait since you either have the disease or you don't. 3. I-1 and I-2 had 6 children.

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Omarion Fladger
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705 views2 pages

Kami Export - Omarion Fladger - Pedigree Genetics Problems

1. The pedigree shows a family history of Huntington's disease. Affected individuals are I-1, II-2, II-3, II-7, and III-3. 2. Huntington's disease is caused by a dominant trait since you either have the disease or you don't. 3. I-1 and I-2 had 6 children.

Uploaded by

Omarion Fladger
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Pedigree Worksheet Name ____________________________________

I
1 2
= Huntington’s
Disease
II 1 2 4 5
3 6 7 8

III
1 2 3 4 5

I-1, II-2, II-3, II-7, and III-3


1. Which members of the family above are afflicted with Huntington’s Disease? _________________________________

2. There are no carriers for Huntington’s Disease- you either have it or you don’t.
dominant
With this in mind, is Huntington’s disease caused by a dominant or recessive trait? ____________________________

6
3. How many children did individuals I-1 and I-2 have? _______________________________________________

2
4. How many girls did II-1 and II-2 have? ______________ 5
How many have Huntington’s Disease? ________________
Uncle/Niece
5. How are individuals III-2 and II-4 related? ________________________ Grandma/grandson
I-2 and III-5? _________________________

6. The pedigree to the right shows a family’s pedigree


for Hitchhiker’s Thumb. Is this trait
recessive
dominant or recessive? _______________________
I
1 2
7. How do you know? _________________________
only 2 people in this family tree have the trait
___________________________________________
II
8. How are individuals III-1 3 4
1 2
cousins/married
and III-2 related? ________________________

9. How would you name the 2 individuals that III


1 2 3 4
IV-1 and IV-3
have hitchhiker’s thumb? ___________________
IV
10. Name the 2 individuals that were
III-1 and III-2
carriers of hitchhiker’s thumb. ______________ 1 2 3

yes
11. Is it possible for individual IV-2 to be a carrier? ___________ their parents are heterozygous
Why? ________________________________________

12. The pedigree to the right shows a family’s pedigree


**half-shaded = carrier of disease
for colorblindness. Which sex can be carriers of I
Females
colorblindness and not have it? ______________________

13. With this in mind, what kind of trait is II


sexlinked/recessive
colorblindness (use your notes)? ______________________

14. Why does individual IV-7 have colorblindness?


their mom was a carrier and their dad was affected
_________________________________________________
III
15. Why do all the daughters in generation II carry the
their dad was affected and its on the X
colorblind gene? ____________________________________
IV
16. Name 2 IV generation colorblind males. IV-1 and IV-5
_________
1 2 3 4 5 6 7 8
Name ____________________________________

Genetics Pedigree Worksheet

A pedigree is a chart of a person’s ancestors that is used to analyze genetic inheritance of certain traits –
especially diseases. The symbols used for a pedigree are:

female, unaffected male, unaffected

female, affected male, affected


Siblings are placed in birth order from left to right and are labeled with numbers.

Each generation is labeled with a Roman numeral.
o Example: we would name an individual II-3 if he/she was in the second generation and the 3rd
child born
------------------------------------------------ ------------------------------

I
1 2 3 4 5 6

II
1 2 3 4 5 6 7 8 9

III
1 2 3 4 5 6 7 8

Try to identify the genotypes of the following individuals using the pedigree above.
(homozygous dominant, homozygous recessive, heterozygous)
homozygous recessive
 III-3: ___________________________________ Homozygous recessive
 I-1: ____________________________________
 II-1: ____________________________________
heterozygous  II-4: ____________________________________
Heterozygous

1. Is this trait dominant or recessive? Explain your answer.


It is a recessive trait because generation II does not have the disease and generations I and III do have it.
___________________________________________________________________________________________
___________________________________________________________________________________________
___________________________________________________________________________________________

2. How can you know for sure that individuals II-3 and II-4 are heterozygous?
Because their offspring have the disease so they are both carriers of it
___________________________________________________________________________________________
___________________________________________________________________________________________

3. Brown eyes are a dominant eye-color allele and blue eyes are recessive. A brown-eyed woman whose father
had blue eyes and whose mother had brown eyes marries a brown-eyed man whose parents are also brown-
eyed. They have a son who is blue-eyed. Please draw a pedigree showing all four grandparents, the two
parents, and the son. Indicate which individuals you are certain of their genotype and where there are more
than one possibilities. bb Bb Bb
Bb
B=brown
b=blue
Bb Bb

bb

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