Full Research
Full Research
The survey was conducted in Jia bagga. The result of survey showed that only 3%
people were found to have tuberculosis
Most of them (59%) will receive treatment from Govt. facility and very few
from T.B clinic, private doctors and hakeems.
The most common reason for non compliance was expensive treatment due to
limited resources. Few of them complained about the non availability of medicine.
From survey it was concluded that knowledge among people regarding treatment of
tuberculosis was very poor.
Out of total population of 504, 275 (54.5%) are male and 229 (45.4%) are female.
57% of the women interviewed had given birth to a child in last two years.
A total of 243 children were less than 14 years of age out of which 93 (38.2%) were
in the range of 1-4 years.
Out of 243 children 134 are male and 109 are female. Out of these 138 go to school
and 105 don’t go to school.
1
Out of the 93 children under 5 years of age 91 are vaccinated for BCG, 90 for
DPT/Hepatitis B, 85 against Measles and all are vaccinated against Polio.
As for as the living standard of the people is concerned 40% are using the supply of
pipe water and an equal number of people are using facilities like well and
handpump. 73% of houses are using flush system latrine and 21% go to the open
field. Out of hundred houses 77 are pakka and 17 are semi pakka.
2
INTRODUCTION
3
tuberculosis, and 2 million people die of the disease world wide. In 2004, around 14.6
million people had active TB disease with 9 million new cases. The annual incidence
rate varies from 356/100,000 in Africa 241/100,000 in the America. TB is the world’s
greatest infectious killer of women of reproductive age and the leading cause of death
among people with HIV/AIDS. [5]
In developed countries, tuberculosis is less common and is mainly an urban disease.
In United Kingdom, TB incidences range from 40/100,000 in London to less than
5/100,000 in the rural south west of England; [6] the national average is 13/100,000.
The highest rates in Western Europe are in Portugal (42/100,000) and Spain
(20/100,000). These rates compare with 113 per 100,000 in China and 64 per 100,000
in Brazil. In the United States the over all tuberculosis case rate was 4.9/100,000
persons in 2004. [7]
The incidence of TB varies with age. In Africa, TB primarily affects adolescents and
young adults. However, in countries where TB has gone from high to low incidence,
such as the United States, TB is mainly a disease of older people. [8]
Tuberculosis is a major public health and developmental problem in Pakistan. The
country has 7th highest burden of TB among the 22 high burden tuberculosis countries
worldwide, according to the WHO Global TB report 2006. Every year, approximately
280,000 people develop TB with an incident rate of 181/100,000 and 62,000 people
die of TB in the country with a mortality rate of 37/100,000. 1 TB case is responsible
for 5.1% of the total national disease burden which is 3rd largest contribution to the
disease burden in Pakistan. As in most low income developing countries there has
been almost no observable decline in TB incidence. The absolute number of cases is
likely increasing due to population growth and worsening poverty. Despite progress
towards the global target for TB control, the treatment success rate (TSR) remains
around 82% against the target of 85% and the case detection rate (CDR) remains at
37% against the target of 70%.
Pakistan adopted the WHO recommended directly observed short course (DOTS)
strategy in 1995. In 2000 thanks to a World Bank funded scheme the program was
expanded to the provinces. Since 2001 the government has been handling TB as a
4
national emergency. DOTS have been extended to 34 of more then 100 districts,
covering 25% of the population. More provinces will be covered by the end of the
year, and the Punjab, the most populated province, will be covered by 2005. [9]
The justification of our study comes from the reason of up rise in TB cases during
past decade specially its prevalence in lower socio-economic environment and the
emergence of multi drug resistant cases due to inadequate surveillance and treatment
plans for TB affected areas. A number of factors prevail in the community like
ignorance, different social customs and taboos, treatment neglect especially for
female community ad above all poor compliance to the treatment because of lack of
education. In the light of above mentioned factors it is pertinent to study the current
practices of people residing in this remote study area. The data collected will help us
to understand the problem in its full magnitude and to improvise new strategies for
counter acting this ailment.
Literature review
Historical aspects
Tuberculosis is an ancient disease, an evidenced the skeletal remains of Neolithic,
pre-Columbian and old kingdom Egyptians person. This disease referred to as
“consumption” in early Hindu writings and as “phthisis” by the Greeks.
Tuberculosis (abbreviated as TB for tubercle bacillus or Tuberculosis) is a common
and deadly infectious disease caused by mycobacterium, mainly mycobacterium
tuberculosis. One third of the world’s current population has been infected by TB, and
new infections occur at a rate of one per second. [2] Not every one infected develops
the full blown disease , asymptomatic, latent infection is most common. However,
one in ten latent infections will progress to active disease which if left untreated kills
more than half of its victims.
The study of tuberculosis dates back to THE CANON OF MEDICIN written by IBN-
A-SINA (Avicenna) in 1020’s. He was the first physician to identify pulmonary
tuberculosis as a contagious disease, the first to recognize association with diabetes,
5
and the first to suggest that it could spread through contact with soil and water. [10] He
developed the method of quarantine in order to limit the spread of tuberculosis. [11]
Although it was established that the pulmonary form was associated with ‘Tubercles’
by Dr. Richard Morton in 1689, [12] due to the variety of its symptoms, TB was not
identified as a single disease until the 1820’s and was not named ‘tuberculosis’ until
1839 by J. L. Schonlein. [13] During the years 1838 to 1845, Dr. John Croghan, the
owne4r of mammoth cave brought a number of tuberculosis sufferers into the cave in
the hope of curing the disease with a constant temperature and purity of the cave’s
air: they died within a year. The first TB sanitorium opened in 1859 in Gorbersdorf ,
Germany (today’s sokolowsko, Poland) by Herman Brehmer. In regard to this claim
‘THE TIMES’ for January 15, 1859 page 5 column 5 carries an advertisement seeking
funds for the Bournemouth sanatorium for consumption, referring to the balance
sheet for the past year, and offering an annual report to prospective donors, implying
that this sanatorium was in existence at least in 1858. The bacillus causing
tuberculosis, mycobacterium tuberculosis, was identified and described on march 24,
1882 by Robert koch. He received the noble prize in physiology or medicine in 1905
for this discovery. [14] Koch did not believe that bovine (cattle) and human
tuberculosis were similar which delayed the recognition of infected milk as a source
of infection. Later this source was eliminated by the pasteurization process. Koch
announced a glycerin extract of the tubercle bacilli as a “remedy” for tuberculosis in
1890, calling it “TUBERCULIN”. It was not effective but was later adopted as a test
for pre symptomatic tuberculosis.[15]
TUBERCULOSIS - DEFINITION
6
mediated hypersensitivity. The usual site of the disease is lungs, but other organs may
be involved” [16]
TUBERCULOSIS - CLASSIFICATION
➢ Pulmonary tuberculosis is most common form of the disease.
➢ Extra pulmonary is tuberculosis affecting organs other than the lungs, most
commonly pleura, lymph nodes, spine, joints, genitourinary tract, nervous
system or abdomen. Tuberculosis may affect any part of the body. [17]
According to WHO, 2 billion people- one third of world’s population- have been
exposed to the tuberculosis pathogen . Annually, 8 million people become ill with
tuberculosis, and 2 million people die of the disease world wide. In 2004, around
14.6 million people had active TB disease with 9 million new cases. The annual
incidence rate varies from 356/100,000 in Africa 241/100,000 in the America. TB
is the world’s greatest infectious killer of women of reproductive age and the
leading cause of death among people with HIV/AIDS. [2]
7
In 2005 the country with the highest estimated incidence of TB was Swaziland,
with 1262 cases per 100,000 people. India has the largest number of
infections, with over 1.8 million cases. [18] In developed countries, tuberculosis is
less common and is mainly an urban disease. In United Kingdom, TB incidences
range from 40/100,000 in London to less than 5/100,000 in the rural south west of
England; the national average is 13/100,000. The highest rates in Western Europe
are in Portugal (42/100,000) and Spain (20/100,000). These rates compare with
113 per 100,000 in China and 64 per 100,000 in Brazil. In the United States the
over all tuberculosis case rate was 4.9/100,000 persons in 2004. [18]
The incidence of TB varies with age. In Africa, TB primarily affects adolescents
and young adults. However, in countries where TB has gone from high to low
incidence, such as the United States, TB is mainly a disease of older people.
The microorganisms usually enter the body by inhalation through the lungs. They
spread from the initial location of the lungs to other parts of body via the blood
8
stream, the lymphatic system, the airways or by direct extension to other organs.
[17]
TUBERCULOSIS - ETIOLOGY
TUBERCULOSIS - PATHOGENESIS
PRIMARY TUBERCULOSIS
The initial lesion of tuberculosis develops before specific cell mediated immune
reaction develop to contain the infection.
A peripheral lesion with enlarged hilar lymph nodes on the chest radiology is
diagnostic for primary complex. Tuberculin conversion usually occurs 3-8 weeks
9
from the time of infection. Bacteriological confirmation by gastric washing,
laryngeal swab or bronchoscopy may yield the diagnosis.
The initial infection, whether, or not it causes overt disease, may resolve
completely by or merely progress to post primary disease in some time in future.
[17]
Extra pulmonary is tuberculosis affecting organs other than the lungs, most
commonly pleura, lymph nodes, spine, joints, genitourinary tract, nervous system
or abdomen. Tuberculosis may affect any part of the body.
TUBERCULOSIS - DIAGNOSIS
HISTORY
10
➢ Persistent cough for three weeks or more
➢ Sputum production which may be blood stained (haemoptosis), shortness
of breath and chest pain.
➢ Fatigue, loss of appetite and loss of weight, night sweats and fever.
First Specimen
At the first interview with the patient a spot specimen is collected; this specimen is
obtained on the spot, after coughing and clearing the back of the throat, under
supervision of a staff member, in a well ventilated area.
Second Specimen
The patient is then given a sputum container for collection of an early morning
specimen before the second interview, which should be on the next working day.
Third Specimen
At the second interview with the patient, the collection specimen is brought by the
patient and a further spot specimen is obtained.
Should the first spot specimen be positive and should the patient not return for the
second interview, an immediate search must be made to find the patient in order to
prevent transmission of microorganisms in the community and deterioration in the
patient’s conditions.
11
TUBERCULIN SKIN TEST
Once patients with infectious TB (bacilli visible in a sputum smear) have been
identified using microscopy services, health and community workers and trained
volunteers observe and record patients swallowing the full course of the correct
dosage of anti-TB medicines (treatment lasts six to eight months). The most common
anti-TB drugs are isoniazid, rifampicin, pyrazinamide, streptomycin and ethambutol.
12
[20]
Sputum smear testing is repeated after two months, to check progress, and again at
the end of treatment. A recording and reporting system documents patients' progress
throughout, and the final outcome of treatment.
By the end of 1998, all 22 of the high burden countries which bear 80% of the
estimated incident cases had adopted DOTS. 43 percent of the global population had
access to DOTS, double the fraction reported in 1995. In the same year, 21 percent of
estimated TB patients received treatment under DOTS, also double the fraction
reported in 1995. [21]
13
OBJECTIVES
➢ To know the current practices of the people living in the community regarding
the management of Tuberculosis.
➢ To study the socio demographic factor of the community concerned with the
practices regarding T.B
➢ To get baseline information regarding the current practices of T.B in the
community by this small scale study.
14
MATERIALS AND METHODS
Study design
It is descriptive cross sectional study.
Study universe
The study was conducted in village Jia bagga, UC 147 Lahore, 40 km from Raiwind.
It was a rural area with one BHU facility and the total population was about 50000.
Duration of study
The study was conducted from 10-03-08 to 17-03-08
Study population
Consisted of all the households sampled in the study
Sample size
A sample of 100 households was selected for the study.
Study tool
A questionnaire booklet consisting of all variables was designed.
Sample technique
It was a simple random sampling.
Data collection
The data was collected with the help of a semi structured questionnaire by the
students of 4th year SIMS. The local community authority was informed about the
education of study and so the data collection was done after their consent’s group of
supervisors and LHV’s also accompanied the students to ensure the quality of data.
15
So finally the data was collected after taking consent from the head of family of
household fulfilling the ethical consideration.
Data analysis
Responses were added in the captor by using Microsoft Excel and Microsoft Word
program, all the responses were entered, data was cleaned and finally data was
analyzed to obtain the results by frequencies tables and charts.
Ethical considerations
Consent was taken and the respondents were assured of full confidentiality.
Results
CHARACTERESTICS OF PERSONS IN THE
SURVEY
16
In survey out of hundred people 3 (3%) were having tuberculosis and 97 (97%) were
not. (Table no. 15)
Of 100 people most common practice of people 59 (59%) regarding treatment of
tuberculosis is govt. health facility, 19 (19%) people approach tuberculosis clinic, 13
(13%) use private doctor facility, 9 (9%) go to hakeem. (Table no. 16)
Reason for non compliance by 65 (65%) people was expensive treatment, 27 (27%)
said about non availability of medicine. Health facility is not accessible by 2 (2%),
non availability of staff by 3 (3%). (Table no. 17)
As regards to keeping live stocks, 79 (79%) had dairy animals, 43 (43%) had weight
bearing animals, 31 (31%) had egg laying birds, 7 (7%) had none. (Table no. 11)
40 (40%) use pipe water as source of water supply, 40 (40%) used mixed (well and
hand pump) and 20 (20%) use hand pump. (Table no. 12)
Latrine system used by 73 (73%) was flush, 21(21%) used open field, 5 (5%) used
bucket, 1 (1%) used pit. (Table no. 13)
77 (77%) houses were pacca, 17 (17%) were semi pacca and 6 (6%) were katcha.
(Table no. 14)
It was noted that out of 100 families included in the study 43 families had population
range between (1-4) years (43%) 48 families had population range between (5-8)
years (48%) and 9 families had population range between (9-12) years (9%). (Table
no. 1)
Out of 504 persons 275 (54.5%) were males and 229 (45.4%) were females. (Table
no.2)
The distribution according to marital status of females in jia bagga showed that out
of 100 females 94 (94%) were married, 3 (3%) were widow, 2 (2%) divorced and 1
(1%) was separated. (Table no.3)
In study out of 100 mothers 57(57%) had child birth in last two years and 43 (43%)
did not. (Table no.4)
The study of household showed that of 243 children less than 4 years of age, 93
(38.2%) were in range of 1-4 years, 87 (35.8%) were in range of 5-8 years, 63
(25.9%) were in range of 5-12 years. (Table no. 5)
17
Of 243 children 134 (55.2%) were males and 109 (44.8%) were females. (Table no.
6)
Out of 243 children 138 (56.7%) were going to school while 105 (43.3%) are did not.
(Table no. 7)
Out of 138 school going children, students who were in 1st class were 27 (19.4%), in
2nd class were 25 (17.9%), in 3rd class were 13 (9.3%), in 4th class were 15 (10.7%), in
5th class 21 (15.1%), in 6th class 10 (7.1%), 7th class 15 (10.7%), 8th class 12 (8.6%).
(Table no. 8)
Vaccination status of child under 5 years of age showed that 91 (98%), were
vaccinated against BCG, 90 (97%) were against DPT and hepatitis B, 93 (100%)
against polio and 85 (91.3%) against measles. (Table no.9)
In survey 34 (34%) were radios, 97 (97%) were T.V, 67 (67%) refrigerators, 72
(72%) bicycles, 43 (43%) motorcycles, 15 (15%) light vehicles. (Table no.10)
Discussion
It is apparent from the study that almost 5-12 persons are residing in 56% of the
households. as we know that T.B is an air borne disease having transmission from one
person to another specially in closed atmosphere so in these households having more
persons the chances of T.B are likely to be more as compared to the household with
less no. of persons. It is very distressing that 43% of children in the study area are not
attending the school as we know that education imparts a lot of things to the students
about their healthy way of life so the children depriving of education are unable to
conceive these healthy ideas and are ultimately at more risk of developing different
ailments.
It is very encouraging that immigration status of the children in the study area is up to
the mark although the BCG coverage is 98% in the community and same has been
reported from different parts of the country but in spite of this the new emerging
cases of T.B puts a question mark on the efficiency of BCG which has been
18
documented in different studies from 0 to 80%.this situation demands careful
evaluation of the efficiency of BCG vaccine. So in future a better plan can be done to
curtail the emergence of new T.B cases.
Regarding the distribution of livestock almost 79% of the households are having one
or other type of dairy animals. In most of the places the human beings and the
animals are residing under the same roof. these households are also involved in the
handling of these dairy animals like milking etc so increasing the risk of development
of bovine T.B in these individuals. 23% of the household resides in katcha or semi
pakka houses as we know that the tuberculosis organisms develop in the damp
atmosphere so these houses are excellent places of breading of these bacilli and
putting these households to catch these infections especially in closed atmosphere.
Although it is a small scale study with a small sample size however it is very
encouraging that only 3% of the study population is suffering from T.B.
This may probably be their 100% claimed for complete compliance for T.B treatment
so preventing the emergence of secondary cases. Secondly it may be because of the
high coverage of BCG vaccination which is a corner stone for the prevention of T.B
in the community. Thirdly most of the people are residing in the pakka houses so
limiting the flourishing of this bug.
The study revealed that more than 80% household consult govt. health facility for
their T.B patients. This is probably because of the establishments of DOTS corners at
govt. hospitals from where they could receive medicines regularly free of cost which
is regarded as heart of the clot’s strategy.
Although dots corners have been established at almost every Govt. health facility still
27% of households claimed the non availability of the centers. This situation demands
immediate consideration and needs to be rectified.
65% of households gave the lame excuse of expensiveness of treatment because dots
centers provide free and regular media. Any how these people need to be imparted
health education regarding the free media availability at these dots centers.
The presence of staff at dots centers need to be assured so that patients can get
medicine at the given time regularly.
19
Conclusion
It is apparent from the study that most of the household consult govt. health facilities
for treatment of T.B. however 2% of the household claimed non availability of drugs
while 65% of the household had poor complaints because of expensive medicine.3%
of the household were not getting medicine because of non availability of staff.
In the light of these facts following recommendations and suggestions are made.
20
➢ More research should be conducted in rural areas like Jia bagga.
➢ National policies, programmes and legislations should be established for
awareness about the treatment of tuberculosis.
➢ DOTS program should be made available in all the health facilities in rural
areas.
Table no. 1
(n = 100)
Population Range
Frequency Percentage (%)
(people)
1-4 43 43
5-8 48 48
9-12 09 09
21
Table no. 2
(n = 100)
22
Table no. 3
(n = 100)
Widow 3 03
Divorced 2 02
Separated 1 01
23
Table no. 4
(n = 100)
Having Child
birth in last 2 Frequency Percentage (%)
years
Yes 57 57
No 43 43
24
Table no. 5
(n = 100)
No. of children
(less than 14 Frequency Percentage (%)
years)
1-4 93 38.2
5-8 87 35.8
9-14 63 25.9
25
Table no. 6
(n = 100)
26
Table no. 7
(n = 100)
School going
Status of Frequency Percentage
children
Yes 138 56.7
No 105 43.3
27
Table no.8
Class status of
Frequency Percentage (%)
child
1st 27 19.4
2nd 25 17.9
3rd 13 9.3
4th 15 10.7
5th 21 15.1
6th 10 7.1
7th 15 10.7
8th 12 8.6
Total 138 100
Table no. 9
28
Frequency distribution of household according to the
vaccination status of children under 5 years of age
(n = 93)
Table no. 10
29
Frequency distribution of household according to
household amenities
(n = 100)
Household
Frequency Percentage (%)
Amenities
Radio 34 34
Television 97 97
Refrigerator 67 67
Bicycle 72 72
Motorcycle 43 43
Light Vehicles 15 15
Table no. 11
30
(n = 100)
Live Stock Number Percentage
Weight bearing animals 43 43%
Dairy Animals 79 79%
Egg Laying Birds 31 31%
None 7 7%
Total 100 100%
Table no. 12
31
(n = 100)
Table no. 13
32
(n = 100)
FLUSH 73 73
BUCKET 05 05
PIT 01 01
OPEN FIELD 21 21
Table no. 14
Frequency distribution of household according to the
House Structure
33
(n = 100)
pacca 77 77%
Table no 15
34
(n = 100)
No 97 97
Table no. 16
35
Treatment source
Frequency Percentage (%)
options
Govt. health facility 59 59
TB clinic/Hospital/DOTS 19 19
Private doctor 13 13
Homeopathic/Hakim 9 09
Table no. 17
36
Reasons for Non Frequency Percentage (%)
compliance
Medicine not available 27 27
Treatment too Expensive 65 65
Side effects of medicine 02 02
Health facility not accessible 02 02
Staff not available 03 03
Don’t Know 01 01
Total 100 100
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