Total No. of Questions : 6] SEAT No.

P645 [Total No. of Pages : 3

[4325]-101
M.Sc. (Semester - I)
PHYSICAL CHEMISTRY
CH-110: Physical Chemistry-I
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) All questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic table/calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.

Physico - Chemical Constants

1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton e
= –9.274 × 10–24 J T–1
12. Nuclear magneton n
= 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I
Q1) Attempt any three of the following : [15]
a) Explain Einstein’s photoelectric effect. How does it support Planck’s
hypothesis of quantization of energy ?
b) Write and explain the terms in the three dimensional time independent
Schrodinger equation. Why is the time dependent Schrodinger equation
not used by chemists ? How can this equation be expressed as an eigen
value equation.
c) Derive the work done in a reversible adiabatic expansion of an ideal gas.
d) Why is entropy called the arrow of time ? Show that the entropy of a
system and surroundings taken together remains constant in a reversible
process but increases in an irreversible process.
e) What is residual entropy ? Explain with the example of the N2O molecule.
Write the corollary of the third law of thermodynamics.
Q2) Attempt any three of the following : [15]
a) Write the combined mathematical statement of first and second law of
thermodynamics. What are the inadequacies of the first law ?
b) Derive the Gibbs - Duhem equation. What are its applications ?
c) Derive the Clayperon equation and give its applications.
d) What are Azeotropes ? Explain the method for separating Azeotropes.
e) What is chemical potential ? Obtain an expression for the free energy of
mixing of ideal gases.
Q3) Attempt any two of the following : [10]
a) Determine the wavelength when a pg particle travels a Gm in a ms.

b) The hexatriene molecule ( 6f -electrons) absorbs light of 250 nm during

the transition to the first excited level. What is the length of the molecule ?
c) Calculate the osmotic pressure at 25°C for a solute concentration of 0.5
mol per litre in a body cell that is impermeable to the solute molecules.

d) Evaluate : Gmix and : Smix if the gases, 1 mole helium, 3 moles neon, 2
moles argon and 2.5 moles xenon are mixed at 25°C.
[4325]-101 2
 SECTION - II
Q4) Attempt any three of the following : [15]
a) What is enzyme catalysis ? Derive Michaelis - menton equation for enzyme
catalyzed reactions.
b) Compare transition state theory and collision theory for the rate of
bimolecular reaction.
c) Why do certain reactions end into explosion ? Explain their mechanism.
d) Which are the techniques for studying kinetics of fast reactions ? Discuss
any one of them.
e) Distinguish between order and molecularity of a reaction. Write the general
expression for order and half-life of a reaction.
Q5) Attempt any three of the following. [15]
a) Derive Eyring equation for reaction rates.
b) Write a note on potential energy surface.
c) Derive the vibrational contribution to the molar entropy and Gibb’s free
energy of the system.
d) Distinguish between Maxwell Boltzman and Bose-Einstein statistics.
e) What are diffusion controlled limits ? Derive the equation for diffusion
controlled reactions.
Q6) Solve any two of the following. [10]
a) Calculate the rotational contributions to entropy and free energy for
oxygen gas at 25°C and 1 atmosphere pressure. The moment of inertia
(I) of O2 gas is 1.9373 x 10-46 kg m2.
b) Calculate the molar residual entropy of a crystal in which the molecules
can adopt six orientations of equal energy at ok.
c) The relaxation time for the fast reaction is 10 μs and the equilibrium
constant is 1x10-3. Calculate the rate constants for the forward and
backward reactions.
d) The decomposition of urea in 0.1 m HCl occurs according to the reaction

NH2CONH2+2H2O ƒ 2NH !4 + CO 32 #

The first order rate constant for this reaction at 71.2°C is 2.77 x 10–5 min–1
with the frequency factor 1.38 x 1013 S–1. Calculate the entropy of
activation at 71.2°C
vvv
[4325]-101 3
Total No. of Questions : 6] SEAT No. :

P648 [Total No. of Pages : 3

[4325]-201
M.Sc. (Semester - II)
PHYSICAL CHEMISTRY
CH-210: Physical Chemistry - II
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the two sections should be written in separate answer books.
2) All questions are compulsory.
3) Figures to the right side indicate full marks.
4) Use of logarithmic table/calculator is allowed.
5) Neat diagrams must be drawn wherever necessary.
Physico - Chemical Constants
1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 JS
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton βe = –9.274 × 10–24 J T–1
12. Nuclear magneton βn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I

Q1) Attempt any three of the following : [15]

a) Predict the intensity distribution in the hyperfine lines of the ESR spectrum
of CD3.

b) Explain in brief Width of spectra lines.

c) What is Raman scattering ? Describe the quantum theory of Raman

effect.

d) Explain the principle of NMR spectroscopy and give its applications.

e) Discuss the rotational vibrational spectrum of a diatomic molecule.

Q2) Attempt any three of the following : [15]

a) Explain dissociation energy and dissociation product with respect to

electronic spectrum.

b) Explain the rule of mutual exclusion and its converse. Sketch and explain
the polarizability ellipsoids of the various modes of vibration of CO2
molecule. Which of these are Raman active ?

c) Write a note on stark effect.

d) Discuss the applications of mössbauer spectroscopy.

e) Explain rotational spectra of symmetric top molecule.

Q3) Solve any two of the following : [10]

a) The rotational spectra of CO has a spacing of 3.84235 cm-1. Determine

the bond length. (At.wt. : C = 12, O = 16)

b) Compute the relative population of states of an electronic spin in magnetic

field of 0.3T at 300K (g=2).

c) The fundamental vibrational frequency of 1H35Cl molecule is 86.63 × 1012 Hz.

Calculate the zero point energy and force constant of HCl.

d) Calculate the population of the first excited level if the ground state has
1000 molecules at 29K. ( E=4.005 × 10-23 J molecule-1)

[4325]-201 2
 SECTION - II
Q4) Attempt any three of the following : [15]
a) Explain different types of G.M. counters.
b) How will you determine the steady state concentration of radicals?
c) Describe the working of Fricke dosimeter. What precautions must be
taken while using it ?
d) Explain the terms i) tracks, ii) spurs, iii) -rays and iv) stopping power.
e) What is separation factor ? Explain electromagnetic method for separation
of isotopes.
Q5) Attempt any three of the following : [15]
a) What is natural nuclear reactor ? Discuss Oklo phenomenon and the
Oklo reactor.
b) How are uranium and plutonium recovered from spent fuels?
c) Discuss India’s three phase nuclear energy programme.
d) What is diffusion phenomenon ? Discuss zone-diffusion technique to
determine diffusion coefficient.
e) How is 14C obtained naturally and artificially ? Give different steps involved
in transformation of 14C from fossils into benzene.
Q6) Solve any two of the following. [10]
a) 10.0 ml KBr solution tagged with radioactive bromine was titrated with
0.01M AgNO3. Addition of 2.5 ml of titrant followed by removal of
AgBr precipitate decrease in activity from 12500 counts for 5 min to
6000 counts for 6 min. Calculate the amount of bromine in original solution.
The detector gave background counts 100 for 10 min.
[Given At.wts. of Ag=108, N=14, O=16, K=39 and Br=80]
b) Potassium - 40 (t1/2 = 1.3 x 109y) constitutes 0.012% of the potassium in
nature. Human body contains 0.35% potassium by weight. Calculate the
radioactivity resulting from potassium-40 decay in a 70 kg man.
c) When single atom of 235U undergoes fission energy obtained is 200 MeV.
Calculate the power released during the fission of 1 kg 235U in 1 day.
vvv
[4325]-201 3
Total No. of Questions : 5] SEAT No. :

P651 [Total No. of Pages : 3

[4325]-301
M.Sc.(Semester - III)
PHYSICAL CHEMISTRY
CH-310: Quantum Chemistry and Solid State Chemistry
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) All questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic table/calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.

Physico - Chemical Constants

1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton Xe = –9.274 × 10–24 J T–1
12. Nuclear magneton Xn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I
Q1) Attempt any four of the following : [20]
a) State and illustrate the conditions for the wave function to be acceptable.

d
b) If  = 3x2 and B̂ = , then show that AB ˆˆ.
ˆ ˆ Ž BA
dx

c) A closed shell electronic configuration always gives rise to the 1S term.

Explain.
d) Give quantum mechanical definition of angular momentum. Explain its
physical significance.
e) Apply the variation method to the system of Helium atom to calculate its
energy.
f) Explain the following :
i) perturbation operator
ii) expansion theorem and
iii) non-degenerate states
Q2) Attempt any four of the following : [20]
a) Set up the secular determinant and write the secular equation for benzene.
b) Explain the mnemonic model of Frost and Musulin used to deduce HMO
energies for annucleus.
c) Compare perturbation method with the variation method on the basis of
the principle, precision and convergence.
d) Comment giving examples on the positive or negative nature of REPE
value for a molecule.
e) Write the secular equations for cyclo-butadiene and hence calculate the

delocalization energy on the basis of Huckel’s approximation.
f) Explain why cyclooctatetraene is unstable but its dianion is stable and
planar.
SECTION - II
Q3) Attempt any three of the following : [15]
a) Compare the resistivities of annealed and unannealed Cu-Au alloys.

[4325]-301 2
 b) Discuss with a suitable example, how the forbidden band gap can be
determined by studying optical properties of semiconductors.
c) Discuss the mechanism of diffusion in solids.
d) Give briefly the occurance of elastic and plastic deformations in solids.
e) Explain the mechanism of a photographic process.
Q4) Attempt any three of the following : [15]
a) Discuss the factors that affect the progress of a Chemical change in
solid-solid reactions.
b) Explain the origin of colour centres in ionic crystals.
c) The fast growing faces are eliminated whereas slow growing faces persist
in a crystal - prove this statement on the basis of geometrical consideration.
d) Write a note on Brillouin zones.
e) Draw and describe the various α-t plots for the decomposition of a
single solid.
Q5) Solve any two of the following : [10]
a) The number of free electrons in a monovalent crystal is 1019 per cm3 at
300K. Calculate the Fermi energy (Eo) in eV.

b) A certain alkali halide ( A + X # ) with molecular weight 74.6 and Nacl

structure has the interionic distance A+ __ X# equal to 0.32 nm. Calculate
the density of the salt for 0.1% Schottky defects.
c) Calculate the Hall constant having carrier density for n-type of
semiconductor as 1016 cm-3 and the charge of electron as 4.803 x 10-10
esu.
vvv

[4325]-301 3
Total No. of Questions : 6] SEAT No. :

P651 [Total No. of Pages : 3

[4325]-302
M.Sc. (Semester - III)
PHYSICAL CHEMISTRY
CH - 311: Nuclear and Radiation Chemistry
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) ALL questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic table, calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.

Physico - Chemical Constants

1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton e
= –9.274 × 10–24 J T–1
12. Nuclear magneton n
= 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I
Q1) Attempt any three of the following. [15]
a) What is nuclear fission ? Give the charge distribution on the fission
fragments.
b) Explain the origin of prompt and delayed neutrons.
c) Write the various types of nuclear reactions based on the nature of
projectile and ejectile.
d) Write a note on photonuclear reactions.
e) Illustrate with example the significance of magic numbers.
Q2) Attempt any three of the following. [15]
a) What are the different forms of potential ? Explain the square well potential.
b) Draw a schematic diagram of nuclear reactor. Explain briefly the function
of various parts of nuclear reactor.
c) Give the classification of reactors on the basis of energy of neutron and
fuel.
d) Discuss the principle of particle induced X-ray emission technique. What
are its advantages ?
e) Discuss the compound nucleus theory of nuclear reactions.
Q3) Attempt any two of the following. [10]
a) Calculate the excitation energy of the compound nucleus formed in the
reaction 24Mg ( , p) 27Al, the energy of = 2.75 MeV(Ls).
Given : Mass of 24 Mg = 23.985045, mass of -particle = 4.00260, mass
of 28Si = 27.97631 amu.

b) In the fission of 239

94 Pu , the fragments have the mass numbers 100 and 138
whose stable isobars are 100
42 Mo
and 138
56 Ba
. What are the primary fragments ?

c) Calculate the approximate critical dimensions of a 239Pu reactor to function

in a steady state (k = 1.04), in the case where the reactor is of a cubical
shape.
Given : The migration area = 0.032m2.

[4325]-302 2
 SECTION - II
Q4) Attempt any three of the following : [15]
a) Discuss the working of Vande Graaff generator.
b) What are the basic components of a particle accelerator ? Explain the
function of each component.

536 E s2
c) What is Szilard-Chalmer reaction ? Derive the expression E= .
A
d) What you understand by the term intrinsic and extrinsic semiconductor ?
Explain the working of surface barrier detector.
e) Explain with suitable example retention in organic compounds.
Q5) Attempt any three of the following : [15]
a) Discuss the free radical theory of radiolysis of water.
b) Explain the various stages of interaction of radiations with biological
cells.
c) Enlist various natural and man made sources of radiations. Describe the
procedure for safe handling of these sources.
d) Distinguish between somatic and genetic effects of radiations.
e) What are the after effects of chernobyl nuclear accident ?
Q6) Solve any two of the following : [10]
a) Find out thickness of lead needed to decrease the activity of Co-60
source from 25,000 cpm to 4000 cpm. Given: e = 0.211 b/e, Z of Pb = 82,
A of Pb = 207, density of Pb = 11.35 g cm-3.
b) Find out dose due 200 mci CS-137 radiation source at a distance of 3
meters. Given : gamma energy = 0.67 MeV.
c) A radiation worker is exposed to following doses of radiations in 6
months.
1 mrad due to -particles
1 mR due to particles
0.01 Gy due to rays.
Find out his effective dose. Is it permissible ?
vvv

[4325]-302 3
Total No. of Questions : 6] SEAT No. :

P652 [Total No. of Pages : 4

[4325]-303
M.Sc.(Semester - III)
PHYSICAL CHEMISTRY
CH-312: Advanced Instrumental Methods of Analysis
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the two sections should be written in separate answer books.
2) All questions are compulsory.
3) Figures to the right side indicate full marks.
4) Use of logarithmic table calculator is allowed.
5) Neat diagrams must be drawn wherever necessary.

Physico - Chemical Constants

1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton e
= –9.274 × 10–24 J T–1
12. Nuclear magneton n
= 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I

Q1) Answer the following (any three) [15]

a) Define and explain the terms isotopic abundance and excitation function.

b) What are the advantages of NAA technique ?

c) Explain the parameters which govern the sensitivity of the NAA technique.

d) How are qualitative and quantitative analyses performed by x-ray

absorption methods ?

e) Describe EPXMA technique with a neat labelled diagram of an electron

microprobe.

Q2) Answer the following (any three) [15]

a) Draw a neat labelled diagram of an ESCA spectrometer and explain with

reference to the samples used in it.

b) Discuss the applications of the ESCA technique.

c) Explain the cylindrical mirror analyzer used in ESCA with a neat labelled
diagram.

d) State the principle of mass spectrometry. Explain the terms molecular

ion and base ion.

e) What are the types of detectors used in mass spectrometry ? Explain the
Faraday Cup detector with a neat labelled diagram.

Q3) Solve the following (any two) [10]

a) 120 mg sample containing 0.021% gold was irradiated in a neutron flux

of 5×108 ncm-2s-1 for 20 hrs. Find the activity of the sample after a
cooling period of 5 hrs.

[Given : r = 100%, i =98.86 b, t1/2 of 198Au = 2.7d].

[4325]-303 2
 b) Aluminium is to be used as windows for a cell for x-ray absorption
measurements with the Ag K W line. The mass absorption coefficient for
aluminium at this wavelength is 2.724 cm2/g, its density is 2.699 g/cm3.
What maximum thickness of aluminium foil could be employed to
fabricate the windows if no more than 3.5% of the radiation is to be
absorbed by them ?

c) In a particular time-of-flight mass spectrometer an ion with m/z 178

required 1.44 μS to strike the detector after emission from the source.
Determine the time needed for an ion with m/z 246 to strike the detector.

SECTION - II

Q4) Attempt any three of the following : [15]

a) Describe the sample introduction in an ICP technique.

b) Discuss the applications of plasma emission spectroscopy.

c) Explain the effect of structural rigidity on the luminescence of an analyte.

d) Write a note on electro chemiluminescence.

e) Discuss the factors which affect the results of thermogravimetric analysis.

Q5) Attempt any three of the following : [15]

a) Draw a typical DTA curve. State its characteristics.

b) With a neat labelled diagram of a cell, describe constant current

coulometric analysis.

c) Explain with examples the application of coulometry to perform redox

titrations. What are the possible sources of error in such titrations.

d) Describe the various excitation signals used in voltametry.

e) Discuss the technique of cyclic voltametry as an analytical tool.

[4325]-303 3
Q6) Solve any two of the following : [10]

a) A 100 ml solution of chloride is coulometrically titrated with silver ion

using a current of 1.00 mA. Calculate the concentration of chloride if the
end point is detected after 102 seconds.

b) An electroactive species yielded a wave with a limiting current of

15.2 μA at an rde which was rotated at 10.0 r/s. What limiting current
would be expected at 30.0 r/s ?

c) A 0.6025 g sample was dissolved and the Ca2+ and Ba2+ ions present
were precipitated as BaC2O4.H2O and CaC2O4.H2O. The oxalates were
then heated in a thermogravimetric apparatus leaving a residue of
unhydrous oxalates that weighed 0.5713 g in the temperature range of
320°C to 400°C and the residue of carbonates that weighed 0.4673g in
the temperature range 580°C to 620°C. Calculate the percentage of Ca
and of Ba in the sample.
[At. wts. : Ba = 137.34, Ca=40, C=12, O=16]

vvv

[4325]-303 4
Total No. of Questions : 5] SEAT No. :

P654 [Total No. of Pages : 3

[4325]-304
M.Sc.(Semester - III)
PHYSICAL CHEMISTRY
CH-314: Polymer Chemistry
(2008 Pattern) (Optional)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) All questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic tables/calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.
Physico - Chemical Constants
1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton Xe = –9.274 × 10–24 J T–1
12. Nuclear magneton Xn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I

Q1) Attempt any three of the following : [15]

a) Define the following terms:

i) polymer ii) copolymer

iii) homopolymer iv) hetropolymer and configuration

b) Describe the secondary bond forces of polymer.

c) What is polymerization ? Discuss various steps involved in addition

polymerization.

d) Distinguish between thermosetting and thermoplastic polymers.

e) Write a note on - ‘Instantaneous composition of polymers’.

Q2) Attempt any three of the following : [15]

a) Describe the kinetics of condensation polymer.

b) Discuss the effect of degree of crystallinity on permeability, hardness

and modulus of a polymer.

c) Write a note on : Crystallinity in Nylon-6.

d) ‘It is almost impossible to obtain a 100% crystalline polymer’ - Explain.

e) Define the term ‘glass transition temperature’ (Tg) and describe any one
method of its determination.

Q3) Solve any two of the following : [10]

a) The extent of reaction for linear step reaction polymerization is 0.90

Calculate the number average degree of polymerization and the weight
fraction of the chain having X n repeating units.

b) Calculate instantaneous composition of polymer when one mole of Vinyl

acetate is copolymerised with three mole of Vinyl Chloride the monomer
reactivity ratios are 0.25 and 1.75 respectively.
[At.wt. C=12, H=1, O=16, Cl=35.5]

[4325]-304 2
 c) The relative viscosities of a fraction of polystyrene of Mn= 275000,
dissolved in tetralin at 293K were

% concentration 0.01 0.025 0.05 0.10 0.25

Relative viscosity( r ) 1.05 1.12 1.25 1.59 2.70

Calculate the constant W and hence estimate relative viscosity of 0.1%

solution of polystyrene with M n = 455000 in the same solvent.

SECTION - II

Q4) Attempt any four of the following : [20]

a) Distinguish between condensation and addition polymers.

b) Discuss the use of TGA technique in the analysis of polymer.

c) Write a note on: Conduction mechanism of conducting polymer.

d) Describe the principle of membrane osmometry.

e) Why does the IR spectra of amorphous and crystalline polymer differ ?

Describe the method of preparation of polymer sample for IR spectrum.

f) Describe the process of calendering with suitable diagram.

Q5) Attempt any four of the following : [20]

a) Derive the stress strain equation for simple stretching of an elastomer.

b) Explain the method to determine molecular weight of polymer by viscosity

measurement.

c) What is molding ? Discuss the injection molding with a neat diagram.

d) What are the techniques used for the production of reinforced plastics.
Explain any one technique with neat diagram.

e) Discuss the viscous flow phenomenon and its mechanism in polymers.

f) Explain the terms: Tenacity, Crimp, Denier, moisture regain and fibre
with reference to textile.

vvv
[4325]-304 3
Total No. of Questions : 4] SEAT No. :

P655 [Total No. of Pages : 3

[4325]-305
M.Sc.(Semester - III)
PHYSICAL CHEMISTRY
CH-315: Special Topics in Physical Chemistry
(2008 Pattern) (Optional)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) All questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic table, calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.

Physical - Chemical Constants

1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton Xe = –9.274 × 10–24 J T–1
12. Nuclear magneton Xn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg

P.T.O.

1
 SECTION - I

Q1) Attempt any four of the following : [20]

a) Write proton condition for Na3PO4 and NaHSe.
b) The pH of 0.01 M solution of a salt of succinic acid is . Find the
concentration of C6H6O4, C4H5O#4 and C4 H4O24# . (Given : pKa1=4.19,
pKa2 = 5.48).
c) Set up the mass balance on sodium and carbonate in 0.1 M Na2CO3 and
acetate in 0.1 M acetic acid.
d) Calculate the pH and concentration of all ionic species for 0.02 M
CH3COOH. [Given : Ka = 1.85 x 10#5 ].
e) What are active and passive sensors ?
f) Discuss the mechanism observed in chemiresistors.
Q2) Attempt any four of the following : [20]
a) What is the influence of surrounding gas atmosphere on the properties
of semiconductor porous ceramics ?
b) Write a note on potentiometric sensors.
c) Discuss adsorption isotherms used in sensors.
d) Define the terms activity, selectivity and inhibitor as used in catalyst.
e) Give the mechanism of the phenol-acetone condensation reaction to get
bisphenol A.
f) Explain the dependence of the observed rate constant for oximation of
acetone on pH at 20°C.
SECTION - II

Q3) Attempt any four of the following : [20]

a) Write a note on scanning tunneling microscope.
b) What are intelligent gels ? Explain their functioning and applications.
c) Explain the technique of Lithography.
d) Write a note on the uses of nanomaterials.
e) Explain the applications of biomimatics.
f) Explain how a smart sensor can test freshness of fish.
[4325]-305 2

2
Q4) Attempt any four of the following : [20]
a) Describe the phase diagram of the water system.
b) Describe the anomalous properties of nanoparticles.
c) Write a note on carbon nanotubes.
d) Describe the principle of preparing tunable smart materials.
e) Write a note on rubber like ceramics.
f) Describe the chemical methods of preparing nano particles.

vvv

[4325]-305 3

3
Total No. of Questions : 4]

P655 [Total No. of Pages : 3

[4325]-305
M.Sc.(Semester - III)
PHYSICAL CHEMISTRY
CH-316: Environmental Chemistry
(2004 Pattern) (Optional)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) All questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic table/calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.
Physico - Chemical Constants
1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton Xe = –9.274 × 10–24 J T–1
12. Nuclear magneton Xn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.

4
 SECTION - I

Q1) Attempt any four of the following : [20]

a) What are the effects of MIC on human health ?
b) Explain the following terms with suitable examples.
i) Occupier ii) Aerosol
iii) Pollutant iv) BOD
v) Trade effluent
c) Write a note on biochemical effect of DDT.
d) Give the classification of air pollutants and discuss the sources of oxides
of carbon.
e) Sketch and label the structure of atmosphere. Explain stratosphere and
troposphere zones of the atmosphere.
f) Distinguish between classical smog and photochemical smog.
Q2) Attempt any four of the following : [20]
a) What do you mean by acidic rain ? Explain the role of air pollutants in
acidic rain.
b) Explain role of petroleum hydrocarbons in pollution.
c) Discuss the main objectives of water sampling.
d) Explain the nature and composition of ground water and sea water.
e) What are surfactants ? Discuss in brief anionic surfactants.
f) Write a note on organic pollutants.

SECTION - II

Q3) Attempt any four of the following : [20]

a) Discuss the impact of noise pollution on human health.
b) Describe the ‘cooling tower’ to prevent thermal pollution.
c) What are the sources of thermal pollution ? Discuss any one in detail.

[4325]-305 2

5
 d) Explain the mechanism of polymer degradation by photosensitizer
additives.
e) How do the modern agricultural practices pollute the soil ?
f) What are soil indicator plants ? Discuss these in detail.

Q4) Attempt any four of the following : [20]

a) Describe how alkalinity in water is determined.
b) What are the sources of cadmium pollution? Explain the effects of
cadmium poisoning.
c) What are carcinogen ? Explain in detail.
d) Explain with examples, the enzyme inhibition by toxic chemicals in human
beings.
e) Discuss the detrimental effects of urban waste products on soil.
f) Write a note on pollution hazards due to lead.

vvv

[4325]-305 3

6
Total No. of Questions : 4] SEAT No. :
P656 [4325]-306 [Total No. of Pages : 2

M. Sc. - II Semester-III
INORGANIC CHEMISTRY
CH - 326 : Organometallic Compounds of Transition
Metals and Homogeneous Catalysis
(2008 Pattern)

Time : 3 Hours] [Max. Marks : 80

Instructions to the candidates:
1) All questions are compulsory and carry equal marks.
2) Figures to the right indicates full marks.
3) At. No : Mn=25, Fe=26, Co=27, Ni=28, Zr=40, Rh=45, Pd=46

Q1) Attempt any FOUR of the following [20]

a) For the following molecules, give the formal oxidation state of the metal,
d-electron count, total valence electrons (TVE) and the number of M-M
bonds if any.
i) [CpCo (CO)]2 (μ-CO) ; ii) (Cyclo C4H4) PdCl2
iii) [Cp.Mn(CO)3] iv) (Cx3-allyl)2 Ni]
iv) Cp2ZrCl2
b) For the following polynuclear complexes, indicate the total number of
electrons, determine the number of M-M bonds present and predict a structure.
i) μ-Co-[Cx4-C4H4) Fe (CO)]2
ii) μ-Co-μ-CRR’-[Cp*Rh]2
c) Give an account of the chemistry structure and bonding of the TT-allyl
complexes of transition metals.
d) Explain the typical reactions of [(x6-C6H6)2 Cr]
e) Describe the systematic classification of n5 cyclopentadienyl T.M.
derivatives along with their preparative methods.

Q2) Attempt any FOUR of the following. [20]

a) Explain - “Ni-C bondlength in nickelocene is longer than the Fe-C.
bondlength in Ferrocene”.

P.T.O.
 b) What is catalysis ? Why do T.M’s acts as catalyst ? Give two examples
of homogeneous catalyst.
c) Discuss in detail production of aldehyde by wacker process.
d) Process a structure of (C5+15)3 Ni3(CO)2 based on IR data. Does each
Ni atom obey the 18 e rule?
e) What haptacities are possible for the following ligands:
i) C2H4 ; ii) Cyclopentadienyl, iii) C6H6 ; iv) Butadiene ;
v) Cyclo octatetraene.

Q3) Attempt any FOUR of the following. [20]

a) Explain the catalytic role of Alkyl Molybdate (VI) compound in
epoxidation reactions.
b) Explain the role of OMC’s as protecting agent.
c) Discuss briefly OMC of group IV in medicine.
d) Predict the product and state which reactions are cyclometallation,
elimination reaction, oxidative addition and which are insertion reactions.

i) Cp (CO)3 Re + Br2 → ?

ii) Cp (CO)2 Fe - CH3 + PPh3 → ?

iii) CO2 (CO)8 + C2F4 → ?
iv) Mn[(COC6H4Me-P) (CO)5] ⎯⎯
hυ
→?
v) [(n5-C5H5)2 MoH2] + [ Mn(CO)5 CH3] → ?
e) Discuss in brief industrial applications of Heck reaction.

Q4) Write short notes on any FOUR [20]

a) Tertiaryphosphine complexes of TM’s.
b) Pianostool compounds.
c) Environmental aspects of OMC’s
d) Non-Rigid molecules in different coordination geometrics.
e) Wikinson’s Catalyst.

***

[4325]-306 2
Total No. of Questions : 4] SEAT No. :
P657 [4325]-307 [Total No. of Pages : 2

M. Sc. - II Semester-III
INORGANIC CHEMISTRY
CH - 330 : Coordination Chemistry, Magnetism and Reaction Mechanism
(2008 Pattern)

Time : 3 Hours] [Max. Marks : 80

Instructions to the candidates:
1) All questions are compulsory and carry equal marks.
2) Neat diagrams must be drawn wherever necessary.
3) Use of logarithmic tables and calculator is allowed.

Q1) Attempt any FOUR of the following [20]

a) Explain the Magnetic properties in dimeric Cu(II) acetate monohydrate.
b) Explain why Fe2 (CO)g is diamagnetic ?
c) Explain the terms
i) Magnetic domain
ii) Ferrimagnetism
d) Discuss the Factors that affect the crystal field stabilization energy in
T.M. complexes.
e) Differntiate between magnetically dilute system and magnetically
concentrated system.

Q2) Attempt any FOUR of the following. [20]

a) Give the nomen clature for the following molecules.
i) Rh(acac) (C2H4)2, ii) [Co(en)2 (Ox)]Cl.
iii) K3[Fe(Ox)3]; 3H2O, iv) Li [Co (N (CH3)4]
v) [Co (NH3) ONO] Cl2
b) Predict the type of magnetic exchange which occurs via the 90° exchange
pathway in the system d1 - d1, d2 - d2, d3 - d3, d8 - d8 and d9 - d9.
c) The extent of exchange interaction in the Cu2O2 ring system is greater
than that in Cr2O2 ring system. Expalin.
d) Explain the solute-solute interaction.
e) The magnetic moment of a certain octahedral Co (II) complex is 4.0 μB.
What is its d-electron configuration. Draw the simplified crystal field
diagram of octahedral system.

P.T.O.
Q3) Attempt any FOUR of the following. [20]
a) What is conjugate base dissociation mechanism ?
b) Discuss in brief isomerisation of octahedral complexes.
c) Discuss the mechanism of electron transfer reaction with reference to
the inner-sphere reaction.
d) Which isomer can you obtain from the following synthetic pathways ?
Give precise explaination and correct structure of the product.
−
i) +NH3
[PtCl 4 ]-2 ⎯⎯⎯ +NO 2
→ ? ⎯⎯⎯ →?

ii) +Cl
[Pt(PR 3 ) 4 ]+2 ⎯⎯ ⎯ +Cl
→ ? ⎯⎯ ⎯ →?
e) Explain in brief Anation reactions.

Q4) Attempt any FOUR of the following. [20]

a) Discuss in brief Reductive elimination reactions.
b) What is mixed order substitution reactions ? Explain with suitable
examples.
c) Write a note on-Raci misation of tris-chelate complexes.
d) “Kinetically inert complexes are Hermodynamically unstable and vice-
versa”. Justify this statement with suitable examples.
e) Complete the reactions:
i) [Co(NH3)6]+3 + H3O* → ? + ?
ii) [Fe(CN)6]-4 + [Fe (CN)6]-3 → ? + ?

iii) ZZX ?
(CH3)3 B + N (CH3)3 YZZ

iv) BF3 + F- → ?
v) C-2(CO)6 + Py → ? + ?

***

[4325]-307 2
Total No. of Questions : 4] SEAT No. :
P658 [4325]-308 [Total No. of Pages : 2

M. Sc. - II Semester-III
INORGANIC CHEMISTRY
CH - 331 : Structural Methods in Inorganic Chemistry

Time : 3 Hours] [Max. Marks : 80

Instructions to the candidates:
1) All questions are compulsory.
2) All questions carry equal marks.
3) Use of log-table and calculator is allowed.

Q1) Attempt the following (any four) [20]

a) Explain the principle underlying DSC.
b) Sketch the Fluorine nmr of BrF5 and comment on the structure of the molecule.
c) Predict the ESR spectro of:
i) Catecholate anion.

ii)

given : IH = 1/2 ; IN = 1
d) How is Mössbauer Spectroscopy useful to characterise oxidataion states
of tin in organotin compounds.
e) Sketch the energy level diagram and transitions for a quadrupole nucleus

with I = 5/2 and .

Q2) Answer any four : [20]

a) Explain the significance of ‘G’ in ESR.
b) Explain the principle of photo electron spectro scopy.
c) Explain Zeeman effect on Mössbauer spectrum of 57Fe compound with
one example.
d) Explain with suitable examples the effect of (i) Heating rate (ii) Furnace
atmosphere (iii) Sample weight on TG curves.
e) The utilized reflecting plane of a LiF analysing crystal has d value of
2.014Å. Calculate the wave length of the second order diffracted line
which has a value of 50.1º

P.T.O.
Q3) Attempt the following (any four) [20]
a) The TG plot of 2.89 mg of sample containing MgSO4.7H2O shows a
single step at on set temperature ~378°k corresponding to formation of
MgSO4.H2O. The mass loss in the step was 0.59 mg. Determine the
percentage of MgSO4.7H2O in the sample.
given At.Wts: Mg = 24.312; S = 32.064; H=1.008; O=15.999
b) Compounds of some elements are used in NMR as shift agents. Which
are these elements ? Explain the use of shift agents in NMR.
c) With the help of ray diagram explain the principle of TEM.
d) How can we determine rate constants of different redox reactions using
cycle voltametry.
e) “NMR is an excellent tool to study Metal phosphine compounds” Justify
the statement.

Q4) Write short notes on (any four) : [20]

a) Photo electron spectroscopy.
b) Braggs Law.
c) Differential Thermal Analysis.
d) Applications of ESR.
e) Isomer shifts in Mössbauer spec

***

[4325]-308 2
Total No. of Questions : 4] SEAT No. :
P659 [4325]-309 [Total No. of Pages : 2

M. Sc. - II Semester-III
INORGANIC CHEMISTRY
CH - 332 : Bio-Inorganic Chemistry :
Inorganic Elements in the Chemistry of Life

Time : 3 Hours] [Max. Marks : 80

Instructions to the candidates:
1) All questions are compulsory.
2) All questions carry equal marks.

Q1) Answer any four [20]

a) Give structural features and functions of metallobiomolecules having
copper as metal center.
b) Which metalloenzymes are responsible for removal of H2O2 ? Discuss their
active site structure and function.
c) How metal - DNA interactions are followed using different spectroscopic
techniques ?
d) Compare between therapeutic and diagnostic applications of
radiopharmaceuticals.
e) Why gadolinium complexes are preferred as MRI contrast agents ?

Q2) Attempt the following (any four) : [20]

a) What are the important structural features of Vit. B12 ? Explain its
biochemical importance.
b) What are hydrogenases ? Explain mechanism of reactions catalyzed by
hydrogenases.
c) Discuss and illustrate the principle of magnetic resonance imaging used
in clinical diagnosis.
d) Distinguish between the oxidative and hydrolytic mechanisms of DNA
cleavage with suitable examples.
e) Explain in detail the structural role of zine with suitable examples.

P.T.O.
Q3) A) Attempt any five: [15]
a) What kind of ionizing radiations are useful in radiopharmaceutical
applications ?

b) Name at least two diseases each caused due to deficiency of cobalt

and copper.
c) Draw and explain the structure of hemocyanin.
d) Give reactions of Cis-DDP (cisplatin) in aqueous, biological and
other media.
e) Draw the structure of chlorophyll and discuss its role in
photosynthesis.
f) Explain 1, 2-shift reactin catalyzed by Vit B12 coenzymes.
B) Fill in the blanks :
g) Cytochrome-c oxidase has ________ at its active site.
h) Pernicions anaemia is caused by __________.
i) Urease has ________ at its active site.
j) The cleavage of DNA caused by OH is called as _______ _____.
k) The trivalent ion of _______used as MRI contrast agent interfes
with Fe3+ .

Q4) Write notes on (any four) : [20]

a) Azurin and plastocyanin.
b) Metal complexes as spectroscopic probes of DNA.
c) Urease.
d) Analog and digital imaging used in radiology.
e) MRI.

***

[4325]-309 2
Total No. of Questions : 6] SEAT No. :
P660 [4325]-310 [Total No. of Pages : 3

M. Sc. - II
ORGANIC CHEMISTRY
CH - 350 : Organic Reaction Mechanism

Time : 3 Hours] [Max. Marks : 80

Instructions to the candidates:
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections should be written in Separate answer books.

SECTION-I
Q1) Attempt any four of the following. [12]
a) Explain the evidences to support NGP.
b) Butane 2, 3-dione exists exclusively in keto form, where as 1,2 -cyclopentane
dione is 100% enolised. Explain.
c) The ionisation constants of 3 and 4 cyano benzoic acids at 300C are
2.51 x 10-4 and 2.82 x 10-4 respectively. Benzoic acid has ionisation
constant ka of 6.76 x 10-5 at 300C. Calculate m and m p for the cyano
substituent.
d) Predict the sign of Hammett ( ) sigma constant for following substituents
giving reasons.
+
P-OH, P-NO2, m-OCH3, m- Nme3
e) Explain the importance of non-linear Hammett Plots.

Q2) Write short notes on any three of the following. [12]

a) Trapping of intermediates.
b) Perkin reaction.
c) Transannular rearrangement.
d) Stevens rearrangement.

P.T.O.
Q3) Predict the products with mechanism for any four of the following. [16]

hv, meOH ?
THF
a) O
O
N2

O O
b) Et 2Zn/CH2I2
?

-
OEt ?
+ PhCHO

c) +
N

CH3

Cl
H2O
: ?
+
d)

e) O ?
COOH
Et3N, Stetter Catalyst

SECTION - II
Q4) Explain any four of the following. [12]
a) Thiamine Pyrophosphate is a natural acyl ion equivalent.
b) Explain the observed enol contents of the following.
1, 3 - cyclohexane dione 95%
1, 2 - cyclopentane dione 99%

33%

c) Ethyl methyl kelon e with benzaldehyde in presence of base and acid

gives two different products.

[4325]-310 2
 d) Ethanolysis of proceeds with total inversion,

whereas formolysis proceeds with retention of configuration.

e) Explain any rearrangement which proceeds through carbene intermediate.

Q5) Suggest mechanisms for any four of the following. [16]

a)

b)

c)

d)

e)

Q6) Answer any four of the following. [12]

a) Give the mechanism of formation of ATP from ADP using
phosphoenolpyruvate.
b) Write a note on halogenation of unsymmetrical ketones in acidic and
basic medium.
c) Explain the use of isotopes in determining mechanism of organic reactions.
d) The acetolysis of both 4-methoxy-1-pentyl brosylate and 5-methoxy-2-
pentyl brosylate give the same mixture of products. Explain.
e) Explain the factors that serve to stabilize carbanion.

***

[4325]-310 3
Total No. of Questions : 6] SEAT No. :

P646 [Total No. of Pages : 7

[4325] - 102
M.Sc. (Part - I) (Semester - I)
INORGANIC CHEMISTRY
CH - 130: Inorganic Chemistry - I
(2008 Pattern)
Time : 3 Hours] [Max. Marks :80
Instructions to the candidates:
1) All questions are compulsory.
2) Answers to the two sections should be written in separate answer books.
3) Neat and labelled diagrams must be drawn whenever necessary.
4) Figures to the right indicate full marks.

Q1) Attempt any three of the following: [15]

a) Develop stereographic projections for the following molecules. Justify

your answer.

i) B3N3H6

ii) trans [Co (NH3)4Cl2]+

b) Using similarity transformation and group multiplication table given for

C2v point group, divide symmetry operations into appropriate classes.
Given: Group multiplication table.

c) Classify any two of the following molecules into appropriate point group
Justify it.

i) In Cl52−

ii) PCl5

iii) AsH3

P.T.O.
 d) Give the properties of irreducible representations for C4v point group
label the irreducible representations with appropriate Mülliken symbols.
Given:character table for C4v.

Q2) Attempt any three of the following: [15]

a) Sketch and explain the following symmetry elements in BF5 molecule and
classify it into appropriate point group.

i) Proper axis of symmetry.

ii) Improper axis of rotation.

b) Discuss the symmetry criterion for a molecule to be optically active.

Predict the optical activity for the following compounds.

i) [Rh H (CO) (PR3)2]

ii) [Co (en)2Cl2]+

c) Find out normalized SALC using projection operator of Eg irreducible

representation which operates on σ I orbital in [Cu(NH3)4]++ ion.

Given:

D4h E 2C4 C 2 2.C2' 2.C''2 i 2.54 σ h 2σv 2.σd

Eg 2 0 -2 0 0 2 0 -2 0 0

d) For a [Ni(CN)5]2– molecule. Find reducible representation for which sigma

bonds form the basis and find out which of the orbitals from the Ni atom
will be offered for sigma bonding.
Given: Character table for C4v point group.

[4325]- 102 2
Q3) Answer the following: [10]

a) Select the proper answer from the given alternatives.

i) A tetrahedral AB4 molecule belongs to Td point group. The symmetry

operations are E, 8C3, 3C2, 6S4, 6 σd. The trace for the reducible
representation when symmetry operations of Td applied to AB4 is,

a) 42001 b) 41002

c) 51201 d) 51002

ii) The centre of inversion is well explained in,

a) Trans, 1, 2 dichloro, dibromo ethane.

b) Cis 1, 2, dichloro, dibromo ethane.

c) Cis 1, 2, dichloro ethane.

d) Cis 1, 2, dibromo ethane.

iii) The SnF4 molecule belongs to following point group.

a) C 4v b) Td

c) D4h d) D 4d

iv) D5h point group is for the molecule

a) SnCl2 b) IF7

c) IF5 d) PCl5

v) The improper axis of rotation is present in.

a) BF5

b) SO2

c) Pyridine

d) NF3

b) What are Weiss indices? Explain with suitable examples. Draw (3 2 1) and
(0 0 1) planes in cubic system.

[4325]- 102 3
 Character table for C4v point group

C 4v E 2C4(z) C2 2σv 2σd Linear, quadratic

rotations

A1 1 1 1 1 1 z x2+y2,z2

A2 1 1 1 –1 –1 Rz

B1 1 –1 1 1 –1 x2–y2

B2 1 –1 1 –1 1 xy

E 2 0 –2 0 0 (x, y) (Rx, Ry) (xz, yz)

1-Group Multiplication Table for C2v

C2 V E C2 σV1 σV2

E E C2 σV1 σV2

C2 C2 E σV2 σV1

σV1 σV1 σV2 E C2

σV2 σV2 σV1 C2 Ε

[4325]- 102 4
 SECTION - II

Q4) Answer any three of the following : [15]

a) Explain the reactions of dihydrogen.

b) Explain in detail nitrides of boron.

c) Give an account of extended silicon-oxygen compounds.

d) With example explain the different oxidation states of nitrogen.

e) Give an account of interhalogen compounds.

Q5) Write notes on any three of the following: [15]

a) Extraction of alkali metals by using crown ethers.

b) Metal fullerene compounds.

c) Uses of noble gases.

d) Synthesis and properties of saline carbides.

e) Sulphur oxoanions.

Q6) a) Draw any five structures: [5]

i) XeF4

ii) B5 H9

iii) Si3O9–6

iv) Li4 (CH3)4

v) IF5

vi) [Cl2 PN]3

[4325]- 102 5
 b) Attempt any five of the following: [5]

i) Fullerene C60 reacts with K to give a compound which acts as a

superconductor at 18 K. The compound is ------

a) K3 C60 b) K4 C60

c) K 16 C60 d) K10C60

ii) PCl3 and PCl5 undergo hydrolysis to produce respectively:

a) H3 PO3 and H3PO3 b) H3PO4 and H3PO3

c) H3PO3 and H3PO4 d) H3PO4 and H3PO4

iii) The correct statement for (CH3)3 N and (SiH3)3 N are -----

i) (CH3)3 N and (SiH3)3 N both are planar.

ii) (CH3)3N is planar and (SiH3)3N is pyramidal.

iii) (CH3)3N is Pyramidal and (SiH3)3N is planar.

iv) (SiH3)3N is Weaker base than(CH3)3N.

a) (ii), (iii) & (iv) b) (iii), (iv)

c) (ii), (iv) d) (i), (iii), (iv)

iv) B10 C2 H12 is isoelectronic with -------

a) B12 H2–
12
b) B12 H12

c) B12 H+12 d) B12 H12 2+

[4325]- 102 6
 v) Alkali metals in liquid ammonia are blue in colour because -------

a) They contain alkali metal cations.

b) The free electron is trapped in solvent cage.

c) An ion pair is formed.

d) An amide ion is formed.

vi) Which one of the following is the correct set of number of lone pair of
electrons in XeF2, XeF4 and XeF6 respectively?

a) 0, 1, 2 b) 1, 2, 3

c) 3, 2, 1 d) 2, 1, 0

+++++++

[4325]- 102 7
Total No. of Questions : 6 ] SEAT No. :

P650 [Total No. of Pages :4

[4325] - 203
M.Sc. - I ( Semester - II)
ORGANIC CHEMISTRY
CH - 250 : Synthetic Organic Chemistry and Spectroscopy
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates:
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections to be written in separate answer books.

SECTION - I

Q1) Explain any four of the following : [16]

a) Outline the details of Reformatsky reaction .
b) Give two methods for preparation of acetanilide from acetophenone.
c) Arrange the following cations as per their stability order and justify your
answer.

d) Cis - 4 hydroxy cyclohexane carboxylic acid undergoes lactonization on

heating where as the trans isomer does not.
e) What are the products of oxidation of compound A on treatment with
i) MnO2 / Acetone / R.T.
ii) KMnO4 / OH OH

P.T.O.
 Q2) Write short notes on any three of the following : [12]

a) Organo copper reagents in organic synthesis.

b) Jone's reagent.

c) Wolf rearrangement.

d) Generation and fate of carbenes.

Q3) Predict the products and suggest the mechanism for any four of the
following : [12]

a)

b)

c)

d)

e)

[4325] - 203 2
 SECTION - II

Q4) Suggest mechanism for any four of the following : [12]

a)

b)

c)

d)

e)

Q5) Attempt any four of the following : [16]

a) Explain the chemical shift observe for the indicated protons.

b) Explain IR absorption frequencies for the following.

IR
c) Assign the chemical shift for the following.
0.9 d 7 Hz 6H
1.5 d 7 Hz 3H
1.85 m 1H
2.45 d 7Hz 2H
[4325] - 203 3
 3.6s 3H
7.1d 8Hz 2H
7.3d 8Hz 2H
d) Calculate l max for the following compound

e) Explain any two of the following.

i) Bathochromic shift.
ii) Diamagnetic Anisotropy.
iii) a – haloketo rule.

Q6) Deduce the structure of any three of the following using spectral data and
justify your answer. [12]
a) M.F : C8 H8 O2.
UV : 250 , 260, 265 nm (Î220, 250 , 200).
IR : Very broad band between 2700 – 3300, 1700, 1600 (w). 1500,
920 cm–1.
H1 NMR : 3.5 ( 12mm, s).
7.2 (30 mm, s).
12.3 (6 mm, s).
b) C8 H10 O2
IR : 3939 , 1599, 1497 , 1173 cm–1.
H1NMR : 2.35 ( t, J= 6 Hz , 10 mm Ex).
3.97 ( q, J = 6Hz, 20 mm).
4.08 (t, J = 6Hz , 20 mm).
6.93 ( d, J = 8Hz, 20mm).
6.97 (t, J =8Hz, 10mm).
7.27 ( t, J = 8Hz, 20 mm).
c) MF : C4 H5 O2 N
UV : Featureless above 210 nm,
IR : 2250; 1750 cm –1
NMR : 3.5 (10 mm, s)
3.8 (15 mm ,s)
d) MF : C7 H14 O
H NMR : 0.9 ( t, 6 H)
1

1.6 ( Sext. 4 H)
2.4 (t, 4 H)
nnn

[4325] - 203 4
 : .oN TAES ]4 : snoitseuQ fo .oN latoT

3 : segaP fo .oN latoT[ 214P

214-]5234[
II - .cS.M
YRTSIMEHC LACITYLANA
ypocsortcepS lacitylanA :094-HC
)VI - retsemeS(
08: skraM .xaM[ ]sruoH 3: emiT
: setadidnac eht ot snoitcurtsnI
.skoob rewsna etarapes ni nettirw eb dluohs snoitces owt eht ot srewsnA )1
.skram lauqe yrrac dna yroslupmoc era snoitseuq llA )2
.yrassecen reverehw nward eb tsum smargaid taeN )3
.dewolla si rotaluclac elbammargorp-noN/elbat cimhtiragol fo esU )4

I - NOITCES
]02[ : gniwollof eht fo ruof yna tpmettA )1Q
.sisylana latnemurtsni ni desu smret gniwollof eht nialpxE )a
rewop gnivloseR )ii rewop evisrepsiD )i
doireP )iii
lacimehc rof lufesu era taht snoiger lartceps citengamortcele eht tsilnE )b
.murtceps noitaidar citengamortcele htiw sisylana
m a e b e l g n i s f o g n i k r o w n i a l p x e d n a m a r g a i d c i t a m e h c s w a r D )c
..retemotohportceps
htumsib neewteb demrof xelpmoc eht rof ytivitprosba ralom etaluclaC )d
evag ,xelpmoc fo noitartnecnoc M5–01 × 7.3 gnivah aeruoiht dna )III(
.mn 074 ta htgnel htap mc 0.1 a ni %3.87 fo ecnattimsnart
na stime edonydhcae dna sedonyd net sah ebut reilpitlumotohp niatrec A )e
noitacifilpma eht etaluclaC .snortcele gnignipmi rof snortcele 2.4 fo egareva
.ebut reilpitlumotohp a fo rotcaf

]02[ : gniwollof eht fo ruof yna tpmettA )2Q

dohtem s’ggarB ebircseD .sisylana latsyrc fo sdohtem noitcarffid eht tsilnE )a
yb deton era redro tnereffid rof noitcelfer eht woH .sisylana latsyrc rof
.euqinhcet siht
fo esu eht ebircseD .senil ACSE ni tfihs lacimehc fo nigiro eht nialpxE )b
.sisylana evitatitnauq ni tfihs lacimehc
.O.T.P
lacitylana s’ti ebircseD .ecnecsenimulimehc fo elpicnirp eht nialpxE )c
.snoitacilppa
.sisylana latsyrc rof dohtem evitprosba yar-X ebircseD )d
eht morf noi etartin ni negortiN fo ygrene gnidnib nortcele si etaluclaC )e
dah ycnacav llehs-renni eht etaerc ot desu saw taht notohp yar-x tnedicni
2.7 saw retemortceps fo noitcnuf krow ehT .mn 259.0 fo htgnelevaw a
.Ve 4.988 saw nortcele derusaem fo ygrene citenik eht dna Ve
] SM 01 × 899.2 = C ,SJ43–01 × 526.6 = tnatsnoc s’kcnalP :neviG[
1– 8

II - NOITCES
]02[ : gniwollof eht fo ruof yna tpmettA )3Q
cinotorp-non dna artceps ecnanoser citengam notorp neewteb hsiugnitsiD )a
.artceps ecnanoser
RMN fo elpicnirp eht nialpxE ?noissecerp romraL yb tnaem si tahW )b
.yroeht lacissalc no desab ypocsortceps
.noitaxaler ecittal-nipS dna nipS-nipS nialpxE ?noitaxaler yb tnaem si tahW )c
,tnemurtsni zHM 003 a no zH 6 = J ,δ5.4 ta retrauq a ta sraeppa notorp A )d
.seitisnetni evitaler s’ti evig dna enil hcae fo zH ni noitisop enil eht setacidni
zHM 06 a ni suelcun ralucitrap a fo MPP ni tfihs lacimehc eht etaluclaC )e
ytisned xalF citengam a ta sbrosba suelcun ecnerefer eht fi tnemurtsni
.suelcun naht retaerg hcihw G 360.0 si taht
.)zHM06 ta noitprosba esuac ot deriuqer G00041 suelcun H1 roF :neviG[

]02[ : gniwollof eht fo ruof yna tpmettA )4Q

RSE fo snoitacilppa eht noitacilppa elpmaxe elbatius htiw ebircseD )a
.sisylana evitatitnauq dna evitatilauq a ni ypocsortcepS
ebircseD .stnenopmoc s’ti lebal ,MES fo margaid citamehcs a warD )b
yleniF a gnisu deniatbo si elpmas dilos fo ecafrus a fo egami eht woh
.snortcele fo maeb dessucoF
: smret gniwollof eht nialpxE )c
RODLE )i
RODNE )ii
s’ti ot ecnerefer htiw ypocsortceps RSE dna RMN neewteb hsiugnitsiD )d
dna sdleif citengam deilppa ,sdnuopmoc ecnerefer ,secruos ,elpicnirp
.srotceted

2 214-]5234[
xulf citnegam a ta nortcele deriapnu na rof devresbo saw ecnanoser a fi )e
deriapnu rof rotcaf-g etaluclac ,zHG 5.9 fo ycneuqerf a dna T 33.0 ytisned
.nortcdle
SJ 01 × 526.6 = h = tnatsnoc s’kcnalP :neviG[
43–

.] T J42–01 × 582.9 = 8µ = notengaM rhoB

1–

ïïï

3 214-]5234[
Total No. of Questions : 6] SEAT No. :

P647 [Total No. of Pages : 4

[4325] - 103
M.Sc. - I (Semester - I)
ORGANIC CHEMISTRY
CH - 150 : Organic Reaction Mechanism and Stereo Chemistry
(2008 Pattern)
Time : 3 Hours] [Max. Marks : 80

Instructions to the candidates :

1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections should be written in separate answer books.

SECTION - I

Q1) Attempt any four of the following : [16]

a) Which of the following compound is stronger base? Why?

b) Methyl cinnamate undergoes electrophilic substitution mainly at meta

position. Explain.

c) Solvolysis of ph CH2 CH2 OBS is faster than n-propylbrosylate. Explain.

d) Reaction of n-propyl bromide with toluene in presence of AlBr3 gives 4-

methyl cumene. Explain.

e) Menthyl chloride on treatment with NaOEt gives only one product whereas
neo-menthyl chloride gives two different products. Explain.

P.T.O.
Q2) Write short notes on any three of the following : [12]

a) Crown ether

b) Jacobsen reaction

c) Factors affecting strength of Acids.

d) SET mechanism

Q3) Predict the products with mechanism (any three) [12]

a)

b) meso-2, 3-dibromobutane

c)

d)

SECTION - II

Q4) Suggest mechanism for any four of the following : [12]

a)

b)

[4325] - 103 2
 c)

d)

e)

Q5) Attempt any four of the following : [12]

a) Which of the following is stronger base? Explain.

b) Give a brief account on metallocene with special reference to ferrocene.

c) Draw the resonance structures of :
i) Phenanthrene
ii) m-nitro anisole
d) The proportion of gauche conformation of 2-hydroxy ethanethiol is more
than expected. Explain.
e) 1- methyl cyclohexane on treatment with HBr/H2O2 gives 2-bromo-1-
methyl cyclohexane. Where as with HCl /H2O2 gives 1- chloro-1 methyl
cyclohexane Explain.

Q6) Attempt any eight of the following : [16]

a) Assign E/Z to the following compounds

[4325] - 103 3
 b) Assign R/S to the chiral center.

c) Pyrrole is stronger acid than pyrrolidine. Explain.

d) Which of the following is optically active? Justify.

e) Identify chiral carbons and find total no. of stereo-isomers in the following
compounds.

f) Assign Re/Si faces to the following.

i) 4-nitrobenzaldehyde ii)

g) Identify aromatic, antiaromatic and nonaromatic amongsts the following:

h) Which of the following compound is more acidic? Justify.

i) Chlorobenzene can not be hydrolysed by using SN1 or SN2 conditions.

Explian.

zzz
[4325] - 103 4
Total No. of Questions : 6] SEAT No. :

P649 [Total No. of Pages : 7

[4325] - 202
M.Sc. -I (Semester - II)
INORGANIC CHEMISTRY
CH - 230 : Inorganic Chemistry - II
(2008 Pattern)
Time : 3 Hours] [Max. Marks : 80

Instructions to the candidates :

1) All questions are compulsory.
2) Answers to the two sections should be written in separate answer books.
3) Neat diagrams must be drawn wherever necessary.
4) Figures to the right indicate full marks.
5) Use of log tables and calculators is allowed.
6) Atomic number [Ti = 22, Mn = 25, Co = 27, Ni = 28 Cu = 29]

SECTION - I

Q1) Attempt any three of the following : [15]

a) Work out possible number of micro states for the following systems.

i) s1d1 ii) 2(p2f4)

iii) f7 iv) d7

v) 3p1 4p1

b) Determine the ground state term for any two metal ions in the following
complexes.

i) [Co(NH3)6]2+ ii) [Ni (en)3]2+ iii) [Mn(H2O)6]2+

P.T.O.
 c) Determine the spin multiplicities of states arising from +2g2 configuration,
when infinitely strong octahedral field is relaxed to strong field using
Bethe’s method of decending symmetry, correlation table and direct
product table.

d) Classify the following transitions in the octahedral complex as orbitally

allowed, vibronically allowed and forbidden transitions. Justify your
answer.

i) Eg → Eg ii) A2u → T2g iii) A2g → T2g

e) The tetrahedral complex [CoCl2 (aniline)2] exibits three d-d bands, the
lowest energy band appearing at 6500 cm–1 (γ1) predict the energy of the
γ2 and γ3 bands. (B = 880 cm–1).

Q2) Attempt any three of the following : [15]

a) Give the spliting of 5D R. S. term in weak cubic field using character

table for pure rotational point group (0).

b) Explain the concept of hole equivalency and mention at least two examples.

c) Explain the following :

i) The electronic spectrum of [Cu (H2O)6]2+ complexion exibits a

shoulder on the main band.

ii) Peaks for forbidden transitions are more sharp than those for allowed
transitions.

d) How would you account for the magnetic moments listed against each
of the following complexes.

i) Na4 [Co (NO2)6] μ = 1.88 BM.

ii) Cs [Ti (SO4)2] μ = 1.84 BM.

[4325] - 202 2
 e) For complex [CoCl4]2– ion spin orbital coupling constant is – 190 cm–1.
The γ1 transition is observed at 2940 cm–1. Calculate effective magnetic
moment of Co2+ ion in the complexion.

Q3) Write short note on (any two) : [10]

a) Tanabe - Sugano diagrams.

b) Quenching of orbital angularmomentum.

c) Chemilumiescence.

SECTION - II

Q4) Answer any three of the following : [15]

a) Give an account of model compounds and spontaneous self assembly.

b) Give account of Principles of coordination chemistry utilised in

bioinorganic chemistry w.r.t. Irving- Williams series.

c) Give the classification of metalloproteins.

d) Give an account of metal Proteins involved in electron transfer reactions.

e) What are the possible pathways of absorption of metal by cell.

Q5) Write short notes - (any three) : [15]

a) Metals in medicine.

b) Dioxygen transport.

c) Acetylcholine receptor.

[4325] - 202 3
 d) Detoxification of mercury.

e) Amino acids as ligands.

Q6) Draw structure of the following (any five) : [10]

a) [2Fe - 2S]+2

b) Tyrosine

c) Aquocobalmin

d) Deoxy hemoglobin

e) Siderophore

f) Flavin

[4325] - 202 4
[4325] - 202 5
[4325] - 202 6
 zzz

[4325] - 202 7
 : .oN TAES ]6 : snoitseuQ fo .oN latoT

7 : segaP fo .oN latoT[ 166P

113-]5234[
)III - retsemeS( II - .cS.M
YRTSIMEHC CINAGRO
noitanimreteD erutcurtS ni sdohteM cipocsortcepS :153-HC
)nrettaP 8002(
08: skraM .xaM[ ]sruoH 3: emiT
: setadidnac eht ot snoitcurtsnI
.yroslupmoc era snoitseuq llA )1
.skram lluf etacidni thgir eht ot serugiF )2
.skoob rewsna etarapes ni nettirw eb dluohs snoitces owt eht ot srewsnA )3

I - NOITCES
]8[ : gniwollof eht fo ruoF yna rewsnA )a )1Q

.ssam yb riap gniwollof eht etaitnereffiD )i

enirolhc fo rebmun eht enimreted ot desu eb nac yrtemortceps ssaM )ii

.nialpxE .sdnuopmoc cinagro ni smota enimorb dna

.nialpxE .RMC ni ecnanoser-ffo revo derreferp si TPED )iii

.RMC yb riap gniwollof eht etaitnereffiD )vi

.sgnir llams ni ezis gnir eht enimreted ot desu eb dluoc lanimeg )v

.nialpxE

.O.T.P
snoitisop enil esohw tetrauq BA na fo mpp δ ni tfihs lacimehc eht etaluclaC )b
]4[ .RMN zHM 001 a ni 282 ,092 ,292 ,003 era )zH( ztreh ni

]61[ : gniwollof eht fo ruof yna rewsnA )2Q

erutcurts eht ecudeD )a

S3 ON9H 8C : F.M
1–
mc 0631 ,5151 ,5761 : RI
)s(641 )d(521 )d(421 )d(63 ).rts ,q(02 :RMC
)s(691 )s(651
)H1 ,zH7 ,tetpes(4.3 )H6 ,zH7 ,d(4.1 :RMP
)H1 ,zH5 ,d(9.7 )H1 ,zH5 ,d(6.7

erutcurts eht ecudeD )b

2
O6 H5 C : F.M
mc 6971
1–
: RI
)s(871 )s(351 )d(89 )t(43 )q(21 :RMC

erutcurts eht tciderP )c

4
O 61 H7 C : F.M
1–
mc 0111 : RI
001 ,).rtS( 15 ,53 :RMC
)pu(001 dna 15 ,)nwod(53 :531 TPED
)H2 ,zH7 ,t(5.4 )H21 ,s(3.3 )H2 ,zH7 ,t(8.1 : RMP

erutcurts eht tciderP )d

4
O 6 1 H0 1 C : .F.M
mc 5271
1–
: RI
)w,s(551 )w,s(521 )rts,t(06 )rts,q(02 )rts ,q(21 :RMC
)w,s(561
)H4 ,zH7 ,q(3.4 )H6 ,s(0.2 )H6 ,zH7 ,t(3.1 :RMP

2 113-]5234[
 atad nevig eht morf erutcurts eht ecudeD )e

3
O 01 H5 C : .F.M
mc 3171
1–
: RI
971 ,57 ,23 ,91,61 :RMC
pu 57 ,23 ,91 ,61 :531 TPED
tnesba 971
)H1 ,m(1.2 )H3 ,zH7 ,d(1.1 )H3 ,zH7 ,d(59.0 :RMP
).hcxe ,H2 ,langis daorb(0.8 ot 5.5 )H1 ,zH6 ,d(1.4

]21[ : eerht yna no seton trohs etirW )3Q

.SM ni rezylana thgilf fo emiT )a

.EON fo snoitacilppA )b

.stfihs lacimehc C31 gnitceffa rotcaF )c

gnilpuoc nips-nips fo ledom cariD )d

II - NOITCES

]8[ : ruof yna rof snoi eht fo siseneg eht nialpxE )a )4Q

)i

)ii

)iii

3 113-]5234[
 96 ,48 ,211 )vi

93 ,55 ,38 ,001 ,821 enonaporp-2-lynehP-1 )v

swohs edixo enelyhte dna enezneb fo noitcaer tfarc ledcirf fo tcudorp ehT )b
]4[ .emas eht fo siseneg eht etirW .29 = z/m ta kaep gnorts a

devresbo eht no tnemmoC .snotorp suoirav ot stfihs lacimehc eht ngissA )a )5Q
]8[ .stnemirepxe ecnanoser elbuod dna stnatsnoc gnilpuoc

)H3 ,zH 5.6 ,d(6.1

)H1 ,zH5.5 & 5.9 ,5.21 ,ddd(68.1

)H1 ,zH2 & 6 ,5.21 ,ddd(20.2

)H9 ,s(63.3

)H1 ,zH9 & 31 ,dd(45.3

)H1 ,zH 1 & 31 ,dd(47.3

)H1 ,zH 5.2 & 5.6 ,qd(49.3

)H1 ,m(30.4

).hcxe ,H1 ,zH 5.3 ,d(03.4

)H1 ,m( 86.4

: tpxe gnilpuoced-nipS
zH2 & 5.9 )dd( → )m(30.4 segnahc 29.3 δ ta noitaidarri )i

zH2 & 5.21 )dd( → )ddd(20.2 segnahc 86.4 δ ta noitaidarri )ii

zH 5.9 & 5.21 )dd( → )ddd(68.1 segnahc

: tpxe EON
.%7 yb δ 68.1 ta langis eht ecnahne 61.1 δ ta noitaidarri

]4[ .smota nobrac suoirav ot stfihs lacimehc eht ngissA )b

4 113-]5234[
 )d(4.56 )t(0.94 )q(7.44 )t(8.52

)d(1.511 )d(3.311 )t(2.301 )d(6.48

)s(0.941 )s(5.441 )s(8.901 )d(6.511

)s(5.341 )s(1.241 )d(5.411 )s(6.761

)s(5.041 )s(9.821 )s(0.321

nevig atad RMP eht gnisu noitcaer fo ecneuqes gniwollof eht etelpmoC )c
]4[ : woleb

: atad RMP

)H1 ,zH51 ,d(0.7 )H1 ,zH 51 ,d(4.6 )H9 ,s(71.1 )H9 ,s(1.1 : A

)H1 ,zH 9.1 & 7.71 ,dd( 17.2 )H9 ,s(31.1 )H9 ,s(80.1 : B
)H1 ,zH01 & 9.1 ,dd(83.4 )H1 ,zH 01 & 7.71 ,dd(52.3

.egap tnecajda eht no nwohs era dnuopmoc nwonknu na fo artceps ehT ) 6 Q

.nwonknu eht fo erutcurts a ta evirra ot atad siht esu dna artceps eht esylanA
]21[ .yfitsuJ

5 113-]5234[
6 113-]5234[
ïïï
7 113-]5234[
Total No. of Questions : 6] SEAT No. :

P662 [Total No. of Pages : 4

[4325]-312
M.Sc. - II (Semester - III)
ORGANIC CHEMISTRY
CH-352: Organic Stereochemistry
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Figures to the right indicates full marks.
3) Answers to the two sections should be written in separate answer books.

SECTION - I
Q1) Answer any four of the following : [16]
a) Discuss the dipole moments of cis and trans 1,2- dibromo cyclohexane.
b) Which form of bicyclo [3.3.1] nonane is more stable? Why?
c) Explain isomers of perhydrophenanthrene and their stability.
d) Bicyclo [2.2.2] octane - 2, 6 - dione (A) does not show acidic properties
while camphonic acid (B) does not readily undergo decarboxylation.

e) Why trans decaline is more stable than cis decaline. Explain with stereo
structure.

Q2) Predict the product in any four of the following and explain stereochemical
principles involved. Justify. [12]

a)

b)

P.T.O.
 c)

d)

e)

Q3) Answer any three of the following : [12]

a) Give the physical methods of resolution.
b) What are the criteria for optical purity. Explain with examples.
c) Explain the method for resolution of dl-alanine.
d) In the IR spectra of following aminoketone the carbonyl absorption around
1700 cm–1 disappears on protonation. Explain.

SECTION - II
Q4) Answer the following (any three) : [12]
a) How NMR spectroscopy is used to find stereochemistry of lactone fusion
in enhydrin?
b) In cinchonine and quinine C8–C9 bond and C3–Vinyl bond are on the
same side. Explain.
c) Predict the product and explain stereochemistry of the product.

d) Explain the stereochemistry of C6 & C13 in codeine. Give evidence.

[4325]-312 2
Q5) Attempt any four of the following : [12]
a) Assign Re/Si configuration of each Sp2 hybridized carbon in following
compound.

b) With reasons, state whether the faces of the carbonyl groups in the
following compounds are homotopic, enantiotopic or diastereotopic.

c) Meso – 3, 4 dihydroxyhexane can be made from two alkenes that are

geometric isomers. Outline the methods that makes this possible.
d) Calculate the ee and the specific rotation of a mixture containing 6 gm of
(+) 2-butanol and 4 gm of (–) 2-butanol. The specific rotation of
enantiomerically pure (+) 2-butanol is +13.5º.
e) Using Felkin rule, explain the following transformation.

Q6) a) Predict the product/s and write stereochemistry of the following reaction
(any four) : [8]

i)

[4325]-312 3
 ii)

iii)

iv)

v)

b) Suggest the reagent and stereochemistry of the following reaction

(any two) : [8]

i)

ii)

iii)

ïïï
[4325]-312 4
Total No. of Questions : 6] SEAT No. :

P663 [Total No. of Pages : 4

[4325]-313
M.Sc. - II (Semester - III)
ORGANIC CHEMISTRY
CH - 353: Free Radicals, Photochemistry and Pericyclic Reactions
& their Applications
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections should be written in separate answer books.
SECTION - I
Q1) a) Write short notes on any two of the following : [8]
i) Dienone-Phenol rearrangement.
ii) Arylation of aromatic rings.
iii) Sandmeyer reaction.
b) Explain any two of the following : [6]
i) Irradiation of benzophenone in the presence of (Ph)2CHOH gives
benzpinacol as the only product.
ii) Irradiation of 2, 2, 5, 5 – tetraphenyl cyclohexanone gives two
products.
iii) Compound A exists primarily in the dimeric form while compound
B exists as a free radical even in the solid state.

Q2) Predict the product/s indicating mechanism in any four of the following:[12]

a)

b)

P.T.O.
 c)

d)

e)

Q3) a) Suggest suitable mechanism for any five of the following : [10]

i)

ii)

iii)

iv)

v)

vi)

b) Explain the role of antioxidants in inhibition of autoxidation with suitable

examples. [4]

[4325]-313 2
 SECTION - II
Q4) a) Draw the correlation diagram for disrotatory conversion of allyl carbonium
ion to cyclopropyl carbonium ion and predict whether the reaction is
thermally or photochemically allowed. [6]
b) Predict the products in any four of the following. Explain the
stereochemistry and mechanism. [8]

i)

ii)

iii)

iv)

v)

Q5) a) Using the Aromatic Transition state concept predict whether the π4s +
π2s cycloaddition reaction is thermally or photochemically allowed. [4]
b) Explain the mechanism for any four of the following : [8]

i)

ii)

iii)

iv)

[4325]-313 3
 v)

Q6) a) Complete the following synthetic sequence indicating all intermediates

and reagents required. [6]

b) Complete any two of the following synthetic sequences indicating all

intermediates and reagents required. [8]

i)

ii)

iii)

ïïï

[4325]-313 4
Total No. of Questions : 4] SEAT No. :

P664 [Total No. of Pages : 3

[4325]-314
M.Sc. - II (Semester - III)
ANALYTICAL CHEMISTRY
CH - 390: Electro Analytical and Current Analytical Methods in
Industries
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory and carry equal marks.
2) Neat diagrams must be drawn wherever necessary.
3) Use of logarithmic tables, non-programmable calculator is allowed.
4) Answer to the two sections should be written in separate answer books.

SECTION - I
Q1) Attempt any four of the following : [20]
a) Distinguish between Voltammetry and Polarography.
b) Explain the following terms and give their significance in Polarographic
analysis.
i) Limiting current
ii) Polarographic maxima
iii) Condenser current
c) Explain construction and working of rotating platinum microelectrode.
What are advantages of it over DME?
d) The diffusion coefficient for Tl + is 2.00 × 10–5 cm2/s, where as for Cd 2+
is 0.72 × 10–5 cm2/s. If a 1.00 × 10–3M solution of Cd 2+ gives a diffusion
current of 8.15 µA, predict the diffusion current for 1.5 × 10–3M Tl+
under the same conditions.
e) Anodic stripping voltammetry is used for the analysis of copper in a sea
water sample using standard addition method. When a 50 ml sample is
analysed it gave a peak current of 0.886 µA. A 5.00 µdm3 spike of 10
ppm Cu2+ is added to the sample and the resulting peak current is 3.52
µA. Calculate the concentration of Cu2+ in ppm in the given sample of
sea water.

P.T.O.
Q2) Attempt any four of the following : [20]
a) Write a critical note on cyclic voltammetry.
b) What are nano-materials? Explain its general applications.
c) What are amperometric titrations? Explain the estimation of zinc by EDTA
using this technique.
d) Draw schematic diagram of cell used in coulometric titration. Discuss
the application of coulometry for complexometric titration.
e) A solution containing 0.50 g of nickel as Ni2+ requires 20 minutes for
complete deposition of nickel at 1.50A. Calculate the quantity of electricity
required.
[At. Wt - Ni = 58.7]
SECTION - II
Q3) Attempt any four of the following : [20]
a) Explain the following terms :
i) Specific activity.
ii) Neutron flux.
iii) Neutron capture cross section.
b) What is the principle of a radiometric titration? Discuss the nature of the
titration curve of calcium by EDTA with solid radioactive silver iodate as
an indicator.
c) State and explain the principle of isotope dilution analysis. Give it’s
applications.
d) The vitamin B-12 content of multivitamin tablet was determined by
dissolving 10 tablets in water. The solution was transferred to 100 ml
volumetric flask and diluted to volume. A 50 ml portion was removed
and treated with 0.5 mg of radioactive vitamin B-12 having an activity of
572 cpm. After homogenization, the vitamin B-12 in the sample was
isolated and purified, producing 18.6 mg with an activity of 361 cpm.
Calculate the amount of vitamin B-12 per tablet.
e) 53.8 mg steel sample was analysed for its manganese content by neutron
activation, 68.5 mg standard steel sample containing 0.9% manganese
was irradiated along with the sample in neutron source and counted under
same experimental conditions. Activities of sample and the standard
counted for 5 minutes were 16597 and 21983 counts respectively.
Calculate the percentage amount of manganese in the steel sample.

[4325]-314 2
Q4) Attempt any four of the following : [20]
a) Explain the principle and instrumentation of Nephelometry. Give the
typical applications of nephelometric method.
b) Explain the principle of DTA technique with suitable example. Describe
the terms exotherm and endotherm in DTA.
c) Draw a schematic diagram of a modern thermo balance and discuss the
significance of each component.
d) Explain the construction and working of optically transparent electrodes.
e) The mass 250 mg hydrated sample of disodium hydrogen phosphate
decreases to 153 mg after heating to 150ºC by TGA. What is the number
of water of hydration in hydrated sample?
(Given: At.Wt. Na = 23, P = 31, H = 1, O = 16).

ïïï

[4325]-314 3
Total No. of Questions : 4] SEAT No. :

P665 [Total No. of Pages : 3

[4325]-315
M.Sc. - II (Semester - III)
ANALYTICAL CHEMISTRY
CH-391: Environmental and Analysis of Industrial Materials
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the two sections should be written in separate answer books.
2) All questions are compulsory and carry equal marks.
3) Neat diagrams must be drawn wherever necessary.
4) Use of logarithmic tables, non-programmable calculators is allowed.

SECTION - I
Q1) Attempt any four of the following : [20]
a) Give the analytical procedure for the estimation of Potassium from
fertilizer.
b) What are colouring constituents of glass? How is iron estimated from
coloured glass?
c) Explain the general scheme of analysis of soap.
d) Enlist the constituents of face powder. Describe the method for estimation
of chloride from sample of face powder.
e) Phosphate containing detergent weighing 0.57 gm was ignited to red hot
to destroy organic matter. The residue was dissolved in hot HCl and
gave H3PO4, the phosphate was precipitated as MgNH4PO4. 6 H2O by
addition of Mg+2 ions followed by aqueous ammonia. After filtration,
washing, drying and ignition at 1000ºC, weight of residue, Mg2P2O7 was
0.441 gm. Calculate percentage of phosphorous in the given sample.
[Given: At. wt: P = 30.97, Mg = 24.31, O = 15.99]

Q2) Attempt any four of the following : [20]

a) What are explosives? How is moisture determined by Karl Fischer
titration?
b) Outline the procedure for determination of Chromium from pigments.

P.T.O.
 c) Describe any one method for determination of calcium in propellant.
d) Borosilicate glass weighing 0.308 gm was fused with sodium carbonate
in platinum crucible, and the melt was converted into boric acid by suitable
process. Mannitol is added in whole solution and titrated with 0.110 N
NaOH using para nitrophenol as an indicator, and 29.40 ml of alkali
required for complete neutralisation.
Calculate percentage of B2O3 in sample of glass.
[Given At. wt : B = 10.81, O = 15.99]
e) 1.507 gm of sample of Brass was dissolved in acid mixture and the
solution was diluted to 250 ml. 150 ml aliquot was used for determination
of Cu and Zn. Copper was determined electro gravimetrically. Weight of
copper deposited after electrolysis is 0.615 gms. Zinc was determined
gravimetrically as Zn2P2O7. The weight of residue was 0.435 gm. Calculate
percentage of Cu and Zn.
[Given : At. wt: Zn = 65.38, P = 30.97, Cu = 63.54, O = 16]
SECTION - II
Q3) Attempt any Four of the following : [20]
a) What is steel? Explain the analytical procedure for the estimation nickel
from steel.
b) Explain the analytical procedure for estimation of calcium from Dolomite
ore.
c) Outline the analytical procedure for the determination of any one of the
following.
i) Ti from ilemenite ore.
ii) Si from bauxite ore.
iii) Cu from cupronickel alloy.
d) 4.510 gm washing soda was dissolved in distilled water and diluted to
250 ml, A 25 ml aliquot of this solution was titrated with 0.110 N HCl
using Methyl orange as an indicator, gave burette reading 30 ml. Calculate
percentage of Na2CO3 in given sample.
[At. wt. Na = 22.98, C = 12, O = 15.99]
e) Analysis of the components of 2.110 gm of shipnail brass yielded 0.0685
gm SnO2 and 0.2824 gm PbSO4. Calculate percentage of Sn and Pb in
alloy.
[Given: At. wt. Sn = 118.7, Pb = 207.2, S = 32, O = 16]

[4325]-315 2
Q4) Attempt any four of the following : [20]
a) Explain the method of determination of hexavalent chromium from waste
water.
b) Write note on (any one) :
i) Cyclone separator.
ii) Anaerobic decomposition.
c) How SOx is generated? Give its hazardous effects on materials. How is it
controlled?
d) Explain the terms COD and BOD. How is COD estimated from Waste
water?
e) Write note on safety measures in industries.

ïïï

[4325]-315 3
Total No. of Questions : 4] SEAT No. :

P666 [Total No. of Pages : 3

[4325]-316
M.Sc. - II (Semester - III)
ANALYTICAL CHEMISTRY
CH - 392: Advanced Analytical Techniques
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the two sections should be written in separate answer books.
2) All questions are compulsory and carry equal marks.
3) Neat diagrams must be drawn wherever necessary.
4) Use of logarithmic tables/non-programmable calculators is allowed.
5) Use of graph paper is allowed.

SECTION - I
Q1) Attempt any four of the following : [20]
a) State and explain Faraday’s laws of electrolysis. Give its important
application.
b) Explain the following terms :
i) Resistor.
ii) Conductance.
iii) Capacitors.
iv) Inductors.
v) Transformers.
c) What is rectification? Describe the working of a diode as a full wave
rectifier.
d) Write a critical note on Flow injection analyzers.
e) Calculate the binary equivalent of 7497 and decimal equivalent of
1110001011.

Q2) Attempt any four of the following : [20]

a) Explain the properties of ideal amplifier as differentiator and integrator.
b) Draw the outline of microprocessor control in X-ray spectrometer.
c) Draw a block diagram of digital computer and explain the function of
each component.
P.T.O.
 d) Calculate the resistance of 0.02 µf capacitor of a frequency 4kHz and
4MHz.
e) A metallic cube of length 5 cm is to be copper plated, if the cube is
immersed in a copper electrolyte. The current is adjusted to 5A and
passed for 30 min. What will be the thickness of deposited copper?
(Given : At. wt. of Cu - 63.54 gm.
Faraday’s Const. (F) - 96487 (Coulomb)
SECTION - II
Q3) Attempt any four of the following : [20]
a) Explain the following terms with respect to AAS.
i) Spectral interference.
ii) Chemical interference.
iii) Ionisation interference.
iv) Releasing agent.
v) Protective agent.
b) Write a note on Resonance ionization spectroscopy.
c) Mention the elements required as micronutrients for the growth of plants.
Explain any one suitable method for determination of Zinc from soil.
d) Compare the ICPS and Direct current plasma emission spectroscopic
techniques of analysis with respect to principle and method of analysis.
e) A 40.0 mg sample of mineral is dissolved in HCl and diluted to 250 ml
and analysed for Calcium by FES. The emission signal is 2.6 units on
the emission scale. Standard Calcium gave the following results.
Ca ppm E.R.
5.0 13
10.0 25
15.0 37
Calculate the percentage of Calcium in mineral.

Q4) Attempt any four of the following : [20]

a) Write a note on :
i) Immunoelectrophoresis.
ii) Immunoblotting.
b) Compare RIA and ELISA techniques. Explain their relative merits and
demerits.

[4325]-316 2
 c) Explain the role of Supercritical Fluid Chromatography as an analytical
tool in pharmaceutical analysis.
d) Explain clinical applications of radioimmuno-assay of Esterogen.
e) 5 ml sample of blood was treated with trichloroacetic acid to precipitate
proteins. After centrifugation the resulting solution was brought to pH 3
and extracted with 2 ml portion of methyl isobutyl ketone containing the
organic lead complexing agent. The extract was aspirated directly into
an air acetylene flame and yields absorbance 0.532 and 0.290 5ml of
aliquot of standard solution containing 0.400 ppm and 0.600 ppm of
lead were treated in same way yielding absorbance 0.396 and 0.599
calculate ppm of lead in blood sample.

ïïï

[4325]-316 3
Total No. of Questions : 4] SEAT No. :

P667 [Total No. of Pages : 2

[4325]-317
M.Sc. - II (Semester - III)
ANALYTICAL CHEMISTRY
CH-380: Pharmaceutical Analysis
(Optional) (2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory and carry equal marks.
2) Answers to the two Sections should be written in separate answer books.
3) Use of logarithmic table/non-programmable calculator is allowed.

SECTION - I
Q1) Attempt any four of the following : [20]
a) Discuss, the unadequate storage conditions and their effects on
pharmaceutical products.
b) Write a note on “prediction of shelf- life of pharmaceutical products”.
c) Explain any one method for biological assay of Insuline.
d) Give limit test for arsenic.
e) Write a note on dry heat steralisation.

Q2) Attempt any four of the following : [20]

a) Explain the analytical procedure for determination of moisture from
pharmaceutical products using K.F. method.
b) Discuss disintegration test for tablets.
c) How sulphated ash from vegetable drug is determined?
d) Explain microbial limit test with respect to preliminary testing and media.
e) Explain in detail ‘tube-assay’ method used in microbial assay.
SECTION - II
Q3) Attempt any four from the following : [20]
a) Discuss in detail clinical study in the development of new drugs.
b) Give brief account of diluents and lubricants used in tablets.
c) Give an account of Gels and Lotions.
P.T.O.
 d) What are aerosols? State the disadvantages of aerosols.
e) 0.33 gm sulphadiazine [C 10H 10N 4O 2S] was dissolved in 10.0 ml
concentrated hydrochloric acid and 50.0 ml water. After cooling this
solution to 15ºC, it was titrated with 0.1 N NaNO2 using acriflavin indicator.
The burette reading recorded was 10.2 ml. Calculate percentage of
sulphadiazine in the given sample.
[Given At. wt. C = 12, H = 1, N = 14, O = 16, S = 32]

Q4) Attempt any four from the following : [20]

a) What are additives? Explain in detail.
b) What are emulsions? How are they prepared?
c) Write a note on FDA.
d) Give an assay of salbutamol.
e) 0.50 gm sample containing calcium lactate [C9H10O6Ca. 5H2O) was
dissolved in 150 ml of water and 2 ml HCl. After dissolution solution
was neutralised with NaOH. This solution was titrated with 0.05 M EDTA
using Muroxide and naphthol green indicator, gave burette reading
18.2 ml. Calculate percentage of calcium lactate in the given sample.
Given : (At. wt. of C = 12, H = 1, O = 16 and Ca = 40.08).

ïïï

[4325]-317 2
Total No. of Questions : 6] SEAT No. :

P668 [Total No. of Pages : 3

[4325]-401
M.Sc. (Semester - IV)
PHYSICAL CHEMISTRY
CH-410: Molecular Structure and Spectroscopy
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Answers to the two Sections should be written in separate answer books.
3) Neat diagrams must be drawn wherever necessary.
4) Figures to the right indicate full marks.
5) Use of logarithmic tables/calculator is allowed.
Physico - Chemical Constants
1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton βe = –9.274 × 10–24 J T–1
12. Nuclear magneton βn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I
Q1) Attempt any three of the following : [15]
a) Explain in brief the origin of NMR spectrum. Would Deuterium nucleus
exhibit NMR spectrum? Explain.
b) Differentiate on the basis of their 13C NMR :
i)

ii)

iii)

c) Write a brief note on: ESR of triplet state.

d) Outline in brief the factors those affect chemical shift in NMR spectrum.
Give suitable example in each case.
e) Discuss applications of PAS.

Q2) Attempt any three of the following : [15]

a) Write a brief note on (any one) :
i) Kramers degeneracy.
ii) Zero-field splitting.
b) What is the g-factor in ESR? Why the g-factor in many ionic crystals is
close to that of the free electron.
c) What is McConell equation? Explain its importance.
d) What is the origin of fine structure in the ESR spectra?
e) Write a short note on ELDOR.

Q3) Solve any two of the following : [10]

a) 32
S has a nuclear spin of 3/2. Calculate the energies of the nuclear spin
states in a magnetic field of 7.50 T ( = 0.4289).
b) The chemical shift of the CH3 protons in acetaldehyde is 2.20 and that of
CHO proton is 9.80. What is the splitting between the methyl and aldehyde
proton resonance in a spectrometer operating at 350 MHz?

[4325]-401 2
 c) The ESR spectrum of Cu2+ in Cs C2O4. H2O shows four lines of equal
intensity at 268.9 mT, 282.3 mT, 295.5 mT, and 307.2 mT. Determine
the effective spin and nuclear spin of Cu2+.
SECTION - II
Q4) Answer any three of the following : [15]
a) Give a brief account of Bragg’s method used in the elucidation of crystal
structure. State its limitations.
b) Compare the usefulness of XRD and electron diffraction techniques.
c) State and explain the phase problem observed in XRD. Outline the
techniques to overcome it.
d) Define the structure factor and relate it to the reflection intensities in X-
ray diffraction pattern.
e) State and explain X-ray diffraction and interference of wave motions.

Q5) Answer any three of the following : [15]

a) Derive the Wierl equation for a diatomic homonuclear molecule.
b) Discuss the advantages of X-ray diffraction technique over neutron
diffraction technique.
c) Distinguish between ferromagnetism and antiferromagnetism.
d) Describe the experimental procedure of Gouy technique.
e) Derive the Langevin equation for the determination of atomic susceptibility.

Q6) Solve any two of the following : [10]

a) Calculate the volume and mass susceptibility of a sample of a complex
with two unpaired electrons at 0ºC.
[Given:density = 1.56 gcm–3, molar mass = 174.8 gmol–1]
b) Calculate the length of unit cell of NaCl crystal having density
2.163 gcm–3.
[Given:Atomic weight of Na = 23, Cl = 35.5]
c) Using Pascal constants and constitutive corrections calculate the molar
susceptibility of toluene.
[Given : A of C = –6.0 × 10 cgs unit
–6

A of H = –2.93 × 10–6 cgs unit

λ:C (in ring) = – 0.24 × 10–6 cgs unit]

ïïï
[4325]-401 3
Total No. of Questions : 6] SEAT No. :

P678 [Total No. of Pages : 4

[4325]-410
M.Sc.
ORGANIC CHEMISTRY
CH-452: Heterocyclic Chemistry Chiron Approach and Medicinal Chemistry
(2008 Pattern) (Semester - IV)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections should be written in separate answer books.

SECTION - I
Q1) a) Explain the following (any three) : [9]
i) Thiophene is resistant to ring opening than furan & Pyrrole.
ii)Indole on reaction with chloroform in alkali gives 3-chloroquinoline
as one of the product.
iii) Purine (pKa 8.9) is much more acidic than imidazole or
benzimidazole.
iv) Pyridine N-oxide readily undergoes electrophilic substitution at the
4-position.
b) Give applications of Supramolecular Chemistry in medicine, data storage
and processing. [3]

Q2) a) Give the reactions of following reagents with Quinoline. [4]

i) 30% Oleum, 90ºC
ii) KNH2, NH3(liq.), –66ºC
iii) LAH, Et2O
iv) TsCl, KCN, CH2Cl2, H2O R.T
b) Predict the product/s in any five of the following : [10]

i)

ii)

P.T.O.
 iii)

iv)

v)

vi)
Q3) a) Write notes on (any two) : [4]
i) Hantzsch Pyridine synthesis.
ii) Use of Thiourea in thiazole synthesis.
iii) Fiest Benary furan synthesis.
b) Suggest suitable mechanism for any two of the following : [6]

i)

ii)

iii)

c) Complete the following reaction sequence (any two) : [4]

i)

ii)

iii)
[4325]-410 2
 SECTION - II
Q4) Answer any three of the following : [12]
a) Write 1C4 and 4C1 conformation of D-Mannose and L-mannose
b) Two isomeric compounds A & B having MF C4H8O4 gives following
reactions.
i) Both A & B forms oximes.
ii) Both A & B forms triacetate.
iii) A on oxidation with HNO3 gives optically inactive acid while B
gives optically active acid. Deduce the structure of A & B.
c) Write Ruff degradation of aldopentose to aldotetrose.
d) Comment on stability of D- Gluco Furanose and D-Gluco pyranose
with special note on anomeric effect.

Q5) a) How will you convert D-mannitol to R-epichlor hydrin. [3]

b) Give the synthesis of L(+) Alanine. [3]
c) Write the Retrosynthetic analysis of (–) shikimic acid. [2]
d) Predict the products (Any three) : [6]

i)

ii)

iii)

iv)

[4325]-410 3
Q6) a) Describe the basic principles of green chemistry. [4]
b) Calculate the % atom economy for following reaction. [2]

c) Answer the following (any two) : [8]

i) Explain in brief the pharmaco kinetics (ADME) of the drug action.
ii) Explain active transport of drug absorption.
iii) Give the theoretical aspect of drug design.
.

ïïï

[4325]-410 4
Total No. of Questions : 6] SEAT No. :

P669 [Total No. of Pages : 4

[4325]-402
M.Sc. (Semester - IV)
PHYSICAL CHEMISTRY
CH - 411: Surface and Electrochemistry
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Answers to the two sections should be written in separate answer books.
3) Neat diagrams must be drawn wherever necessary.
4) Figures to the right indicates full marks.
5) Use of logarithmic table/calculator is allowed.
Physico - Chemical Constants
1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton βe = –9.274 × 10–24 J T–1
12. Nuclear magneton βn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I
Q1) Attempt any three of the following : [15]
a) Derive the relation πσ = KT for the film of adsorbed solute in dilute
solutions.
b) Explain the term wetting and nonwetting. Explain wetting as a capillary
action phenomenon.
c) Describe with neat labelled diagram gravimetric method for measurement
of adsorption of gas on solid.
d) Discuss briefly adsorption of gas on porous solids.
e) Give a critical comparison of various models used for multilayer
adsorption.

Q2) Attempt any three of the following : [15]

a) What are Zeolites? Explain with example how they are used to isolate
radionuclides.
b) Write a short note on heterohomogeneous catalysis.
c) Explain what is catalyst deactivation. Describe different ways of catalyst
deactivation.
d) What is specific surface area of solid? Discuss various methods used to
determine it.
e) Discuss geometrical theory of heterogeneous catalysis.

Q3) Solve any two of the following : [10]

a) One gram of activated charcoal has surface area of 1000 m2. Considering
complete coverage as well as monomolecular adsorption, how much
ammonia in ml of STP would be adsorbed on the surafce of 2.5 g
charcoal? Diameter of ammonia molecule is 0.3 nm.
b) The adsorption of p-xylene on KC-8 adsorbent is studied at various
temperatures. The equilibrium constant varies with temperature according
1
to the equation in K = –122.88 × – 4.88. Calculate the adsorption
T
activation energy.
c) The surface tension of an aqueous solution varies with concentration of
solute according to equation = 70 – 350C, C = 0.05. Calculate the
value of K for the variation of surface excess of solute with concentration.
Where K is defined by equation K = j. C . The temperature is 25ºC.
[4325]-402 2
 SECTION - II
Q4) Attempt any three of the following : [15]
a) Describe the structure of water when ion is present in it.
b) Explain the term ionic strength. How does it affect i) thickness of ionic
atmosphere ii) the mean activity coefficient of an electrolyte?
c) Deduce the extended Debye-Huckel equation for appreciable
concentration.
d) Write the Butler-Volmer equation and explain the terms involved in it.
How current density varies with overpotential?
e) Discuss the electrical double layer theory using storn model.

Q5) Attempt any three of the following : [15]

a) Explain the terms :
i) Galvani potential
ii) Outer potential
iii) Surface potential
iv) Electrochemical potential
b) Discuss the Wagner-Traud mechanism for corrosion of ultrapure metals.
c) Write short note on Li ion battery.
d) Explain the terms :
i) Fradic efficiency
ii) Voltage efficiency
iii) Maximum efficiency
iv) Overall efficiency
e) Discuss the electrosynthesis of benzene from phenols and aniline from
benzene.

Q6) Solve any two of the following : [10]

a) Evaluate the constants A and B for water at 25ºC. Hence calculate mean
activity coefficient of KNO3 in water at 25ºC when ionic strength is 0.01,
dielectric constant of water is 78.3 and ion size parameter a = 3Å.
b) When dilute potassium hydroxide was electrolysed using nickel cathod,
the over potential was found to be 0.394 V to maintain a current density
0.01 A cm–2 and 0.148 to maintain a current density 0.0001 A cm–2.

[4325]-402 3
 Calculate the transfer coefficient and exchange current density for
hydrogen/hydrogen ion equilibrium at nickel cathod in the given medium
at 298 K.
c) Calculate the Zeta potential in Helmholtz double layer in a solution having
dielectric constant 78, ionic charge density 1015esu and separation between
the Helmholtz layer is 10–5 cm.

ïïï

[4325]-402 4
Total No. of Questions : 4] SEAT No. :

P670 [Total No. of Pages : 3

[4325]-403
M.Sc. (Semester - IV)
PHYSICAL CHEMISTRY
CH-414: Biophysical Chemistry and Related Techniques
(2008 Pattern) (Optional)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) All questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic table/calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.
Physico - Chemical Constants
1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton βe = –9.274 × 10–24 J T–1
12. Nuclear magneton βn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I
Q1) Attempt any four of the following : [20]
a) Discuss the strategies adopted to study biophysical chemistry in cell
processes.
b) Calculate the pKa of a buffer system showing pH 4.5 if the base
component is 0.17M and acid component is 0.15M.
c) What are good and poor solvents? What is the measure of the
effectiveness of a solvent to dissolve a macromolecule?
d) Write a note on the role of ATP to fuel cell processes.
e) Discuss the role of Caldesmon in smooth muscle contraction.
f) Explain the role of Osmotic pressure in cell biology.

Q2) Attempt any four of the following : [20]

a) Explain the cage structure of the water molecules around a solute
molecule.
b) Explain the primary, secondary, tertiary and quaternary structures of
proteins in brief.
c) Discuss the role of heat-shock proteins to facilitate refolding of proteins.
d) Comment on the ability of water to form H bonds with polar solutes like
the HCO 3− anion.
e) Write a note on ‘flickering clusters’.
f) What is buffering capacity of a buffer system. When is it maximum?
Explain acidosis.
SECTION - II
Q3) Attempt any four of the following : [20]
a) Discuss briefly the composition of a cell membrane.
b) Draw and explain the graph showing various events of action potential.
c) What is all or none law? Explain.
d) Discuss briefly the factors affecting ‘enzyme activity’.
e) Derive Michaelis-Menton equation for enzyme catalysis.
f) What are biopolymers? State their characteristics and applications.

[4325]-403 2
Q4) Attempt any four of the following : [20]
a) Describe the diffraction method for determination of molecular weight
of a biopolymer.
b) State the principle of X-ray diffraction. How is it used to determine the
molecular weight of an asymmetric macromolecule?
c) What is Electrophoresis? State its types. Explain any one.
d) Discuss the theory of optical rotatory dispersion.
e) Discuss the applications of circular Dichroisn.
f) What are micelles and bilayers? Differentiate between these.

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[4325]-403 3
Total No. of Questions : 5] SEAT No. :

P671 [Total No. of Pages : 3

[4325]-404
M.Sc. (Semester - IV)
PHYSICAL CHEMISTRY
CH-415: Special Topics in Nuclear Radiation Chemistry
(2008 Pattern) (Optional)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the TWO sections should be written in SEPARATE answer books.
2) All questions are COMPULSORY.
3) Figures to the RIGHT SIDE indicate FULL marks.
4) Use of logarithmic table/calculator is ALLOWED.
5) Neat diagrams must be drawn WHEREVER necessary.
Physico - Chemical Constants
1. Avogadro Number N = 6.022 × 1023 mol–1
2. Boltzmann Constant k = 1.38 × 10–16 erg K–1 molecule–1
= 1.38 × 10–23 J K–1 molecule–1
3. Planck Constant h = 6.626 × 10–27 erg s
= 6.626 × 10–34 J s
4. Electronic Charge e = 4.803 × 10–10 esu
= 1.602 × 10–19 C
5. 1 eV = 23.06 k cal mol–1
= 1.602 × 10–12 erg
= 1.602 × 10–19 J
= 8065.5 cm–1
6. Gas Constant R = 8.314 × 107 erg K–1 mol–1
= 8.314 J K-1 mol–1
= 1.987 cal K–1 mol–1
7. Faraday Constant F = 96487 C equiv–1
8. Speed of light c = 2.997 × 1010 cm s–1
= 2.997 × 108 m s–1
9. 1 cal = 4.184 × 107 erg
= 4.184 J
10. 1 amu = 1.673 × 10–27 kg
11. Bohr magneton βe = –9.274 × 10–24 J T–1
12. Nuclear magneton βn = 5.051 × 10–27 J T–1
13. Mass of an electron me = 9.11 × 10–31 kg
P.T.O.
 SECTION - I
Q1) Attempt any three of the following : [15]
a) ‘99mTc is called as a work horse of nuclear medicines’. Explain.
b) Write a note on radiation therapy.
c) Discuss the principle and procedure of Positron Emission Tomography
technique.
d) Outline the procedure for Li–6 isotope separation.
e) What are the advantages and disadvantages of food irradiation by ionizing
radiations?

Q2) Attempt any three of the following : [15]

a) Write a brief note on pre-mordial nucleosynthesis.
b) Discuss p, r and s processes in nucleosynthesis.
c) Write down the properties of quark confinement era, GUT era and inflation
era.
d) Define maximum permissible dose. How much is the value of MPD for
radiation workers for different organs.
e) Give an account solid and gadeous radioactive waste management.

Q3) Solve any two of the following : [10]

a) Write down the reactions in C-N-O bicycle.
b) In technicium generator, activity of loaded 99Mo is 12,000 cpm. What
will be the activity of 99mTc if extracted after 5 hours of loading? Given
t1/2 of 99Mo = 66h & 99mTc = 6.01h.
c) Find out thickness of lead required to reduce a close from 10Gy/h to
10mGy/h. Given : eµ = 0.211 b/e, A of Pb = 207, Z of Pb = 82, density of
Pb = 11.35 g/cm3.
SECTION - II
Q4) Answer any four of the following : [20]
a) Discuss the phenomenon of radiolysis of hydrocarbons.
b) Write the possible reactions occurring in the radiolysis of methanol.
c) Discuss the problems encountered in the preparation of target by reactor
irradiation.

[4325]-404 2
 d) Explain the necessity of thin targets and techniques for their preparation.
e) Write a note on carriers used in nuclear reaction.
f) Discuss Sworski and Schwarz relationships for the yield of molecular
products and the solute concentration.

Q5) Answer any four of the following : [20]

a) Define Scavenging. Explain the phenomenon of radical Scavenging with
a suitable example.
b) Describe a typical radiometric titration curve obtained in precipitation
reaction where in substance and reagent both are labelled. Write the
experimental procedure for the same.
c) Explain the principle and technique of radiometric titration curves based
on interaction of β-particles with the substance.
d) Discuss applications of radiometric titrations.
e) Explain competition kinetics with a suitable example.
f) 10 cc of LiCl labelled with radioactive chloride was titrated with 0.01 M
AgNO3 Addition of 2.0 cc of titrant showed a loss in activity from 10,000
counts per min to 10,000 counts per two min. Calculate the concentration
of lithium chloride.

ïïï

[4325]-404 3
Total No. of Questions : 4] SEAT No. :

P672 [Total No. of Pages : 2

[4325]-405
M.Sc. - II (Semester - IV)
INORGANIC CHEMISTRY
CH-430: Inorganic Solids and Heterogenetics Catalysis
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Draw neat figures wherever necessary.

Q1) Answer the following (any four) : [20]

a) How are heterogeneous catalysts classified? Give two examples each.
b) Explain the formation of SO2 in the presence of a vanidium (V) catalyst.
c) “Metal nanoparticles are effective catalysts for hydrogenation”. Justify.
d) Giving suitable examples differentiate between linear and cyclic inorganic
polymers.
e) Explain with the help of MOT the structure and conductivity of
polythiazylion.

Q2) Attempt any Four : [20]

a) Write an account on “Synthesis of Zeolites”.
b) What is meant by photocatalysis? Explain one photocatalysed reaction
in detail.
c) What are peroxyacids? Explain the acidic properties of these compounds.
d) Explain the basic principles involved in heterogeneous catalysis.
e) Draw the structures of the following :
i) [NSCl]3 ii) [Si4O12]8–
iii) [Si2O5]2– iv) [V10O28] 6–
v) [Pt19(CO)22] 4–

P.T.O.
Q3) Answer any Four : [20]
a) Explain the use of X-Ray Diffraction technique for determining the structure
of zeolites.
b) Explain the significance of volcano diagram in heterogeneous catalysis.
c) Write an account on Heteropolyanions of Molybdenum.
d) Explain the role of sulphides as catalysts.
e) Explain the following terms :
Polysilylenes, Silicones, Silicon rubber and Feldspar.

Q4) Write notes on any four : [20]

a) ALPO & SAPO.
b) MCM–41.
c) Structural features of SN compounds.
d) Ultramarines.
e) Fixed bed reactor.

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[4325]-405 2
Total No. of Questions : 4] SEAT No. :

P673 [Total No. of Pages : 2

[4325]-406
M.Sc. - II (Semester - IV)
INORGANIC CHEMISTRY
CH-431: Material Science
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Neat diagrams must be drawn wherever necessary.
3) Figures to the right indicate full marks.
4) Use of logarithmic table & calculator is allowed.

Q1) Attempt any Four of the following : [20]

a) What is the difference between soft wood and hard wood? Explain with
example. Describe the different layers in the cross section of a tree stem.
b) Explain the type of diffusion mechanism in solids.
c) Explain the different types of plots of α vs T in solid state reactions?
d) Explain the mechanism of fluorescences and phosphorances with the
help of energy level diagram.
e) What are nanomaterials? Name the various method for synthesis of
nanomaterials. Why these methods are important?

Q2) Attempt any Four of the following : [20]

a) Explain the BCS theory for superconductor.
b) What is point defect? Explain the Schottky and Frenkel detect in solids?
c) What is Biomaterials? Explain classification of Biomaterials.
d) Explain the how thermocopal operate on the basis of principle of Peiter
and Seebeck effect?
e) What are the different types of magnetism?

P.T.O.
Q3) Attempt any Four of the following : [20]
a) What is hysteresis loop? Saturation magnetisation of F.C.C. iron is 1750
KA/m2. Calculate the net magnetic moment per iron atom in the crystal.
Given : Lattice parameter of F.C.C. is 2.87ºA
and 1BM = 9.273 × 10–24 A/m2.
b) Derive the expression of Curie law.
c) In ‘Ge’ energy gap is 0.75 eV. What is wavelength of which starts
absorption of light?
d) Calculate the conductivity of pure silicon at room temp. when
concentration of carrier is 1.6 × 1010 per cm3, Take µe = 1500 cm2/V.S
and µn = 500 cm3/V.S.
e) In an n-type semiconductor, the fermi level lies 0.3 eV below the
conduction band at room temp. If the temp. is increased to 330ºK. Find
the position of fermilevel. (Room temp = 300ºK)

Q4) Attempt any Four of the following : [20]

a) What do you mean by a transistor? Give its types and explain any one of
them.
b) Write a short note on Hall effect and Hall coefficient.
c) What is crystal growth? Explain the crystal growth of hydration reaction.
d) What are Main types of synthetic fiber’s used to produce fiber reinforced
plastic composite materials?
e) Write a note on oil well cement and Sol gel process.

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[4325]-406 2
Total No. of Questions : 9] SEAT No. :

P674 [Total No. of Pages : 3

[4325]-407
M.Sc. - II
INORGANIC CHEMISTRY
CH-445: Inorganic Applications in Industry, Biotechnology and
Environmental Chemistry
(Semester - IV) (2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Attempt any two sections from the following.
2) Both sections should be written in the same answer book.
3) All questions are compulsory.
4) Figures to the right indicate full marks.
5) Neat diagrams must be drawn wherever necessary.
6) Use of logarithmic table/calculator is allowed.

SECTION - I
Inorganic Applications in Industry
Q1) Attempt any three of the following : [15]
a) What is meant by term pigment? Explain the following properties of
Inorganic pigments.
i) Colour and tints.
ii) Reactivity with vehicle.
iii) Resistance to light.
iv) Chemical resistance.
b) Explain the methods for electroplating of precious metals.
c) Give an account of preparation of copper dyes from O-hydroxy diaryl
azo compounds and O-halogeno-O-hydroxy diaryl azo compounds.
d) Explain the microstructure of soft and hard wood.
Q2) Attempt any three of the following : [15]
a) What is the difference between a pigment and dye? Explain the use of
chromium in dyeing of wool using azo dyes? Give the structure of the
compounds involved.

P.T.O.
 b) How are redox centers to PVP electrode coating? Explain the effect of
increasing the positive potential of the platinum electrode on
electrodeposition.
c) Which types of isomerisms are seen in chromium and cobalt complexes
of tridentate azo compounds? Explain any one type of isomerism.
d) Explain two methods of electroplating of tin.

Q3) Attempt any two of the following : [10]

a) Explain the production and properties of glass fibers.
b) Write a note on - Luminous and Fluorescent pigments.
c) How do complexes such as Prussian blue and Ferrocene modify the
behaviour of electrodes during electroplating.
SECTION - II
Environmental Chemistry
Q4) Attempt any three of the following : [15]
a) What is powerball? Draw a schematic diagram of plant for producing
powerball. How is the hydrogen gas liberated from a powerball. How is
the power ball manufactured.
b) What does tertiary treatment in a sewage treatment plant remove from
the waste stream?
c) Draw a schematic diagram that shows all the components of an AAS.
How is an aqueous sample introduced into AAS? The metal ion analyte
has a positive charge, how does it become a neutral atom?
d) What is the main source of cadmium pollution in the environment? List
four industrial uses of cadmium. What is galvanised iron? Are smokers
more at risk for cadmium poisoning?

Q5) Attempt any three of the following : [15]

a) List four forms of biomass. What is the energy yield obtained from
burning biomass? List the advantages and disadvantages of using biomass
as a source of energy.
b) Determine pE for waste water that contains 5 × 10–4MS–2. Does this
waste water favour oxidation or reduction?
S + 2 e → S−2 , pE o = − 8.47

[4325]-407 2
 c) Draw a schematic diagram of a Phosphoric Acid Fuel Cell (PAFC).
What reactions are occurring at the cathode and anode? Show over all
reaction.
d) What is meant by point and nonpoint sources of pollution? Give an
example of each.

Q6) Write short notes (any two) : [10]

a) Tidal power and Wind power.
b) Primary and Secondary sludge.
c) Reverse Osmosis.
SECTION - III
Biotechnology
Q7) Answer any three of the following : [15]
a) Which principles of Genetics are used in biotechnology?
b) Give an overview of chemical reactions involved in the production of
biohydrogen.
c) What is renin? Describe an experiment to demonstrate the effect of
different factors on the action of renin on milk.
d) Why are living cells called miniature factories.

Q8) Attempt the following (any three) : [15]

a) Describe the steps involved in the synthesis of insuling from clone DNA
segment.
b) How are variations induced in plants? Explain one method in detailed.
c) Discuss the ethical and socio-economic issues related with impacts of
Biotechnology.
d) Write an account on production of lactic acid.

Q9) Write short notes on any two : [10]

a) DNA mapping.
b) Applications of single cell proteins.
c) Vaccines.

ïïï
[4325]-407 3
Total No. of Questions : 6] SEAT No. :

P675 [Total No. of Pages : 4

[4325]-408
M.Sc. - II (Semester - IV)
ORGANIC CHEMISTRY
CH - 450: Chemistry of Natural Products
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections should be written in separate answer books.

SECTION - I
Q1) a) Outline the steps involved in the following synthetic sequences. Indicate
the reagents and discuss the mechanism and stereochemistry involved
(any three) : [12]

i)

ii)

iii)

iv)

P.T.O.
 b) Explain the importance of Navasaka’s boron template methodology in
construction of molecule X already possessing four contiguous
stereogenic centres. [4]

Q2) Answer the following (any three) : [12]

a) What is Dieckmann cyclisation? How this cyclisation helps in establishing
stereochemistry of ring fusion in Hardwickiic acid?
b) Give evidences to establish the presence of i) Ar − CH 2 − N − C − group
||
O
and ii) presence and position of ethyl group in hydroxy camptothecein.
c) What is the role of acetic anhydride, chloroacetic anhydride, 30Cl2 in
structure determination of camptothecein?
d) “Podophyllotoxin and picropodophyllin are stereoisomers and not
structural isomers”. Justify.

Q3) a) 3', 4'- demethyl podophyllotoxin has the following structure. [6]

i) How will you prove the trans B/C ring fusion?

ii) How will you distinguish between the –OH group from ring B and
ring D chemically and by physical methods?
iii) How will you separate podophyllotoxin from 3', 4'-demethyl
podophyllotoxin by chemical method?
b) Complete the following synthetic sequences using appropriate reagents
and intermediates. Justify. [6]

[4325]-408 2
 SECTION - II
Q4) a) Discuss the transamination reaction and the role of pyridoxal phosphate
in the reaction. [4]
b) Suggest biogenetic scheme for any three of the following : [12]

i)

ii)

iii)

iv)

[4325]-408 3
Q5) Answer any two of the following : [12]
a) Indicate the position of label in each step and in the final product from
the following biogenetic conversion.

b) Suggest the biogenetic pathway for

c) Write all steps in the following conversion.

Q6) a) Answer any one of the following : [6]

i) Discuss the biogenesis of from Ornithine [2–14C].

Clearly indicate the position of label in each step.
ii) Outline the steps involved in the conversion of Farnesyl
pyrophosphate to lanosterol and discuss the mechanism involved.

b) Indicate the position of label in each step and in the final product from
the following biogenetic conversion. [6]

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[4325]-408 4
Total No. of Questions : 6] SEAT No. :

P676 [Total No. of Pages : 4

[4325]-409
M.Sc. - II (Semester - IV)
ORGANIC CHEMISTRY
CH - 451: Synthetic Methods in Organic Chemistry
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Answers to the two sections should be written in separate answer books.
SECTION - I
Q1) a) Explain any two of the following : [6]
i) Advantage of Fmoc as a protecting group over BOC.
ii) Aldol style condensation by using silyl triflate.
iii) Isotactic propene polymerisation by using titanium- aluminium
catalyst.
b) Complete any two of the following conversions by using suitable reagents.
[6]
i)

ii)

iii)

Q2) Predict the product in any four of the following: [12]

a)

P.T.O.
 b)

c)

d)

e)

Q3) a) Write short notes on any two of the following : [6]

i) Solid phase peptide synthesis.
ii) Grubb’s catalyst.
iii) Wacker oxidation.
b) Explain any one of the following : [4]
i) Synthesis of 1, 2-dicarbonyl compounds involve umpolung of
reactivity.
ii) Use of 9-BBN in organic synthesis.
c) Provide a suitable synthesis using organo silanes as one of the step.
Write all the reagents and intermediates (any two) : [6]

i)

ii)

iii)

SECTION - II
Q4) a) Explain any two of the following : [6]
i) Olefination by Peterson’s reaction.
ii) Acyl anion equivalent can be prepared from enol ethers.
iii) Synthetic applications of tetracarbonyl ferrate dianion.

[4325]-409 2
 b) Explain the use of any two of the following : [6]
i) Sonogashira coupling in organic synthesis.
ii) MOMCl and MEMCl
iii) Bu3SnH

Q5) a) Complete the following transformation using the reagents given below.
Arrange the reagents in proper order (any two) : [6]

i)

ii)

iii)

b) Give the synthetic equivalent of (any three) the following synthone.

Illustrate your answer with one example of each. [6]

i)

ii)

iii)

iv)

[4325]-409 3
Q6) Using retrosynthetic analysis, suggest a suitable method to synthesize of the
following (any four) : [16]

i) ii)

iii) iv)

v) vi)

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[4325]-409 4
Total No. of Questions : 4] SEAT No. :

P679 [Total No. of Pages : 2

[4325]-411
M.Sc. - II (Semester - IV)
ANALYTICAL CHEMISTRY
CH-481: Bioanalytical and Forensic Science
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the two sections should be written in separate answer books.
2) All questions are compulsory and carry equal marks.
3) Neat diagrams must be drawn wherever necessary.
4) Use of logarithmic table/non-programmable calculator is allowed.

SECTION - I
Q1) Attempt any four of the following : [20]
a) How is benzoic acid estimated from food sample?
b) Write note on ‘Sweetening tablet’.
c) What is Pasteurization? How is it verified?
d) Describe analytical method for estimation of pectin content from Jam.
e) Sulphite containing food sample 31.8 gm was subjected to Tanner method
and the titre value obtained with 0.01 M NaOH was 8.9 ml. Calculate the
amount of SO2 in the sample. [At. wt. S = 32, O = 16]

Q2) Attempt any four of the following : [20]

a) Discuss the microkjeldahl method for estimation of protein.
b) Explain suitable method for estimation of glucose.
c) Define Saponification value of oil. Discuss the method used for the
estimation of the saponification value of oil.
d) Explain the procedure for estimation of vitamin-C.
e) How is HMF content of honey estimated? Calculate HMF content of
sample of honey (100g) if absorbance of unit path length was 0.190.

P.T.O.
 SECTION - II
Q3) Attempt any four of the following : [20]
a) How are barbiturates isolated from biological samples by ‘procedure A’.
b) State the principle and explain the procedure for extraction of caffeine
from biological sample.
c) Outline ‘Procedure Type B’ for isolation and identification of
amphetamine.
d) How is heroin isolated from sample?
e) Biological sample was analysed for amphetamine content using gas
chromatographic method, which gives following observations :-
i) Internal standard concentration = 1.6 µg/ml.
ii) Peak height for amphetamine = 8.3
iii) Peak height for amphetamine in standard reference solution = 4.30.
iv) Peak height for standard in specimen = 2.5.
v) Peak height for internal standard in reference solution = 1.62.
vi) Volume correction factor = 0.6.
Calculate the concentration of amphetamine in the given sample.

Q4) Attempt any four of the following : [20]

a) Define the terms :
i) Opium derivative
ii) Manufacture
iii) Coca-leaf
iv) Alcohol.
b) Explain rules related to manufacture of manufactured drugs.
c) How are dutiable goods transferred from one bonded warehouse to
another bonded warehouse?
d) Write note on offences and penalties in psychotropic substance acts.
e) Give and explain the types of Ayurvedic preparations containing alcohol.

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Total No. of Questions : 4] SEAT No. :

P680 [Total No. of Pages : 2

[4325]-412
M.Sc. - II (Semester - IV)
ANALYTICAL CHEMISTRY
CH-490: Analytical Spectroscopy
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) Answers to the two sections should be written in separate answer books.
2) All questions are compulsory and carry equal marks.
3) Neat diagrams must be drawn wherever necessary.
4) Use of logarithmic table/Non-programmable calculator is allowed.
SECTION - I
Q1) Attempt any four of the following : [20]
a) Explain the following terms used in instrumental analysis.
i) Dispersive power ii) Resolving power
iii) Period
b) Enlist the electromagnetic spectral regions that are useful for chemical
analysis with electromagnetic radiation spectrum.
c) Draw schematic diagram and explain working of single beam
spectrophotometer.
d) Calculate molar absorptivity for the complex formed between bismuth
(III) and thiourea having 3.7 × 10–5M concentration of complex, gave
transmittance of 78.3% in a 1.0 cm path length at 470 nm.
e) A certain photomultiplier tube has ten dynodes and each dynode emits
an average of 4.2 electrons for impinging electrons. Calculate the
amplification factor of a photomultiplier tube.

Q2) Attempt any four of the following : [20]

a) Enlist the diffraction methods of crystal analysis. Describe Bragg’s method
for crystal analysis. How the reflection for different order are noted by
this technique.
b) Explain the origin of chemical shift in ESCA lines. Describe the use of
chemical shift in quantitative analysis.
c) Explain the principle of chemiluminescence. Describe it’s analytical
applications.
d) Describe X-ray absorptive method for crystal analysis.
P.T.O.
 e) Calculate 1s electron binding energy of Nitrogen in nitrate ion from the
incident X-ray photon that was used to create the inner-shell vacancy
had a wavelength of 0.952 nm. The work function of spectrometer was
7.2 eV and the kinetic energy of measured electron was 889.4 eV.
[Given: Planck’s constant = 6.625 × 10–34Js, C = 2.998 × 108MS–1]
SECTION - II
Q3) Attempt any four of the following : [20]
a) Distinguish between proton magnetic resonance spectra and non-protonic
resonance spectra.
b) What is meant by Larmor precession? Explain the principle of NMR
spectroscopy based on classical theory.
c) What is meant by relaxation? Explain Spin-Spin and Spin-lattice relaxation.
d) A proton appears at a quartet at 4.5δ, J = 6 Hz on a 300 MHz instrument,
indicates the line position in Hz of each line and give it’s relative intensities.
e) Calculate the chemical shift in PPM of a particular nucleus in a 60 MHz
instrument if the reference nucleus absorbs at a magnetic Flux density
that is 0.063 G which is greater than the sample nucleus.
[Given: For 1H nucleus 14000G required to cause absorption at 60MHz).

Q4) Attempt any four of the following : [20]

a) Describe with suitable example the applications of ESR Spectroscopy
in qualitative and quantitative analysis.
b) Draw a schematic diagram of SEM, label it’s components. Describe
how the image of a surface of solid sample is obtained using a Finely
Focussed beam of electrons.
c) Explain the following terms :
i) ELDOR
ii) ENDOR
d) Distinguish between NMR and ESR spectroscopy with reference to it’s
principle, sources, reference compounds, applied magnetic fields and
detectors.
e) if a resonance was observed for an unpaired electron at a magnetic flux
density 0.33 T and a frequency of 9.5 GHz, calculate g-factor for unpaired
electron.
[Given: Planck’s constant = h = 6.625 × 10–34Js
Bohr Magneton = µB = 9.285 × 10–24J T–1].

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[4325]-412 2
Total No. of Questions : 4] SEAT No. :

P681 [Total No. of Pages : 3

[4325]-413
M.Sc. - II (Semester - IV)
ANALYTICAL CHEMISTRY
CH-491: Polymer Technology
(2008 Pattern)
Time :3 Hours] [Max. Marks :80
Instructions to the candidates :
1) All questions are compulsory and carry equal marks.
2) Answers to the two sections should be written in separate answer books.
3) Draw diagram wherever necessary.

SECTION - I
Q1) Attempt any four of the following : [20]
a) How polymers are classified on their morphological behaviour?
b) Write a note on Emulsion polymerisation.
c) Derive kinetic rate equation for living chain polymerisation.
d) Discuss the effect of radiation on Teflon.
e) What is polymer degradation? Explain degradation by high energy
radiation.

Q2) Attempt any four of the following : [20]

a) Give salient features of suspension polymerisation.
b) Give method of preparation, types and uses of silicone polymers.
c) Complete the following reactions.

i)

ii)

P.T.O.
 iii)

iv)

v)

d) Discuss two types of termination reactions in free radical chain

polymerisation.
e) State, giving reasons the type of copolymer formed when the two
monomers have the following reactivity ratios.
r1 r2
Case I 0.02 0.01
Case II 55.0 0.01
Case III 1.0 1.0
SECTION - II
Q3) Attempt any four of the following : [20]
a) Explain softening temperature and flammability of the polymers.
b) Write a note on calendering.
c) Give types of fibres. Explain Wet spinning method.
d) Explain the following terms :
i) Resistance to solvents.
ii) Vapour permeability and weathering.
e) A suspension containing equal masses of particles of molecular weights
30,000 and 40,000 respectively. Calculate the number average molecular
weight (Mn) and weight average molecular weight (Mw) .
(Given : M1 = 30,000 g/mole, M2 = 40,000 g/mole)

Q4) Attempt any four of the following : [20]

a) Explain the role of X-ray diffraction in structure determination of
polymers.
b) Describe in detail an ebulliometry method used for determination of Mn of
polymers.
[4325]-413 2
 c) Explain the role of carbon black in reinforcement of elastomers.
d) What is sol-gel? Explain aqueous chemistry of metal alkoxides.
e) A 0.4378 gm of carboxy terminated and hydroxy terminated polybutadiene
dissolved in mixture of ethanol and toluene. It was titrated against 0.1314
N alcoholic KOH. The burette reading was 6.2 ml. Calculate average
molecular weight of polymer.

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[4325]-413 3