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Sequential (Sepsis-Related) Organ Failure Assessment Score

This document outlines the Sequential [Sepsis-Related] Organ Failure Assessment (SOFA) score, which is used to track organ dysfunction in sepsis patients over time. It assigns 0-4 points for six organ systems (respiration, coagulation, liver, cardiovascular, central nervous system, and renal) based on clinical measures like oxygen levels, platelet count, bilirubin, blood pressure, Glasgow Coma Scale, creatinine, and urine output. Higher scores indicate more severe organ dysfunction from sepsis.

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Elfira Sutanto
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86 views

Sequential (Sepsis-Related) Organ Failure Assessment Score

This document outlines the Sequential [Sepsis-Related] Organ Failure Assessment (SOFA) score, which is used to track organ dysfunction in sepsis patients over time. It assigns 0-4 points for six organ systems (respiration, coagulation, liver, cardiovascular, central nervous system, and renal) based on clinical measures like oxygen levels, platelet count, bilirubin, blood pressure, Glasgow Coma Scale, creatinine, and urine output. Higher scores indicate more severe organ dysfunction from sepsis.

Uploaded by

Elfira Sutanto
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Sequential [Sepsis-Related] Organ Failure Assessment Score

Score
System 0 1 2 3 4
RESPIRATION

PaO2/FIO2, mm Hg ≥400 (53.3) <400 (53.3) <300 (40) <200 (26.7) with <100 (13.3) with
(kPa) respiratory support respiratory support

COAGULATION

Platelets, ×103/µL ≥150 <150 <100 <50 <20

LIVER

Bilirubin, mg/dL <1.2 (20) 1.2–1.9 (20–32) 2.0–5.9 (33–101) 6.0–11.9 (102–204) >12.0 (204)
(µmol/L)

Cardiovascular MAP ≥70 mm Hg MAP <70 mm Hg Dopamine <5 or Dopamine 5.1–15 Dopamine >15 or
dobutamine (any dose)a or epinephrine ≤0.1 epinephrine >0.1
or norepinephrine ≤0.1a or norepinephrine >0.1a

CENTRAL NERVOUS SYSTEM

Glasgow Coma Scale 15 13–14 10–12 6–9 <6


scoreb

RENAL

VAS058_0320INT
Creatinine, mg/dL <1.2 (110) 1.2–1.9 (110–170) 2.0–3.4 (171–299) 3.5–4.9 (300–440) >5.0 (440)
(µmol/L)

Urine output, mL/d <500 <200

Abbreviations: FIO2, fraction of inspired oxygen; MAP, mean arterial pressure; PaO2, partial pressure of oxygen.
a Catecholamine doses are given as µg/kg/min for at least 1 hour.
b Glasgow Coma Scale scores range from 3–15; higher score indicates better neurological function.

Source: The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) M Singer et al. JAMA 2016;315:801

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