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Drug Study

This document summarizes a drug study of Aripiprazole (Abilify) including its classification, indications, mechanism of action, dosage and administration, adverse reactions, and nursing considerations. Aripiprazole is an atypical antipsychotic used to treat schizophrenia, acute and maintenance of manic and mixed episodes associated with bipolar disorder, as well as adjunct treatment of major depressive disorder. It works as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and as an antagonist at 5-HT2A receptors. Common adverse reactions include CNS and neurological effects. Nurses should monitor for and report signs of neuroleptic malignant syndrome.

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0% found this document useful (0 votes)
2K views

Drug Study

This document summarizes a drug study of Aripiprazole (Abilify) including its classification, indications, mechanism of action, dosage and administration, adverse reactions, and nursing considerations. Aripiprazole is an atypical antipsychotic used to treat schizophrenia, acute and maintenance of manic and mixed episodes associated with bipolar disorder, as well as adjunct treatment of major depressive disorder. It works as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and as an antagonist at 5-HT2A receptors. Common adverse reactions include CNS and neurological effects. Nurses should monitor for and report signs of neuroleptic malignant syndrome.

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unkown user
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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DRUG STUDY

Date Generic Brand Classificat Indication


Mechanism Dosage & Time Adverse Nursing
Name Name ion of Action Frequency Given Reaction Consideration
05-08- Therapeut Schizophr Psychotrop ORAL CNS: · Monitor
21 Aripiprazol Abilify ic: enia. ic activity FORMUL akathisia, and report signs
e antipsych Acute and may be ATIONS: confusion, of neuroleptic
otics, maintena due to Aripipraz depression, malignant
mood nce agonist ole IR: drowsiness syndrome,
stabilizers
therapy of activity at Monother , including
manic and dopamine apy: extrapyrami hyperthermia,
Pharmaco mixed D2 and -Initial dal diaphoresis,
logic: episodes serotonin dose: 15 reactions, generalized
dihydroca associate 5-HT1A mg orally fatigue, muscle rigidity,
rbostyril d with receptors once a hostility, altered mental
bipolar and day insomnia, status,
disorder antagonist -Target lightheaded tachycardia,
(as activity at dose: 15 ness, changes in
monother the 5-HT2A mg orally manic blood pressure
apy or receptor. once a reactions, (BP), and
with Also has day; may impaired incontinence.
lithium or alpha1- increase cognitive Symptoms
valproate) adrenergic dose function, typically occur
. Adjunct blocking based on nervousnes within 4–14
treatment activity. clinical s, days after
of Therapeuti response. restlessnes initiation of
depressio c Effects: Dose s, seizures, drug therapy,
n in Decreased increases, suicidal but can occur at
adults. manifestati if needed, thoughts, any time during
Agitation ons of should be tardive drug use.
associate schizophre at 2-week dyskinesia.
d with nia; intervals to Resp: · Be alert for
schizophr Decreased allow time dyspnea. new seizures or
enia or mania in to achieve CV: increased
bipolar bipolar steady bradycardia seizure activity,
disorder. patients; state. , chest especially at
Decreased -Maximum pain, the onset of
symptoms dose: 30 edema, drug treatment.
of mg/day hypertensio Document the
depression. n, number,
Decreased orthostatic duration, and
agitation hypotensio severity of
associated n, seizures, and
with tachycardia report these
schizophre . EENT: findings
nia or blurred immediately to

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