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Test Reference Range Significance of Abnormal Findings

This document provides reference ranges and clinical significance for various blood tests. It lists normal ranges for red blood cell count, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, white blood cell count, reticulocyte count, total iron-binding capacity, iron, serum ferritin, platelet count, hemoglobin electrophoresis, Coombs test, international normalized ratio, and prothrombin time. It explains that levels outside the normal ranges can indicate conditions like anemia, infection, blood clotting disorders, and hemoglobinopathies.

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Jojelyn Yanez Balili
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53 views

Test Reference Range Significance of Abnormal Findings

This document provides reference ranges and clinical significance for various blood tests. It lists normal ranges for red blood cell count, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, white blood cell count, reticulocyte count, total iron-binding capacity, iron, serum ferritin, platelet count, hemoglobin electrophoresis, Coombs test, international normalized ratio, and prothrombin time. It explains that levels outside the normal ranges can indicate conditions like anemia, infection, blood clotting disorders, and hemoglobinopathies.

Uploaded by

Jojelyn Yanez Balili
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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TEST REFERENCE RANGE SIGNIFICANCE OF ABNORMAL FINDINGS

Females: 4.2 – 5.4 million u/L Decreased levels indicate possible anemia or hemorrhage.
RBC Males: 4.7 – 6.1 million u/L Increased levels indicate possible chronic hypoxia or
polycythemia vera.
Females: 12 – 16 g/dL
Hemoglobin Males: 14 – 18 g/dL Same as for RBC.

Females: 37% – 47%


Hematocrit Males: 42% - 52% Same as for RBC.

Increased levels indicate macrocytic cells, possible anemia.


Mean Corpuscular Volume 80 – 95 f/L (femtoliter) Decreased levels indicate microcytic cells, possible iron
(MCV) deficiency anemia.

Mean Corpuscular 27 – 31 pg (picograms) Same as for MCV.


Hemoglobin (MCH)
Mean Corpuscular Increased levels may indicate spherocytosis or anemia.
Hemoglobin 32 – 36 g/dL or 32% - 36% Decreased levels may indicate iron deficiency anemia or a
Concentration (MCHC) hemoglobinopathy.

Increased levels are associated with infection, inflammation,


White Blood Cell Count autoimmune disorders, and leukemia.
(WBC) 5000 – 10,000/mm³ Decreased levels may indicate prolonged infection or bone
marrow suppression.

Reticulocyte Count Increased levels may indicate chronic blood loss.


0.5% - 2.0% of RBCs Decreased levels indicate possible inadequate RBC perfusion.

Total iron-binding Increased levels indicate iron deficiency.


capacity (TIBC) 250 – 460 mcg/dL Decreased levels may indicate anemia, hemorrhage, hemolysis.

Increased levels indicate iron excess, liver disorders,


Females: 60 – 160 mcg/dL hemochromatosis, megaloblastic anemia.
Iron (Fe) Males: 80 – 180 mcg/dL Decreased levels indicate possible iron deficiency anemia,
hemorrhage.

Serum ferritin Females: 10 – 150 g/dL Same as for Iron.


Males: 12 – 300 g/dL
Increased levels may indicate polycythemia vera or malignancy.
Platelet Count 150,000 – 400,000/mm³ Decreased levels may indicate bone marrow suppression,
autoimmune disease, hypersplenism.

Hgb A₁: 95% - 98% Variations indicate hemoglobinopathies.


Hemoglobin Hgb A₂: 2% - 3%
electrophoresis Hgb F: 0.8% - 2%
Hgb S: 0%
Hgb C: 0%
Hgb E: 0%
Direct and indirect Negative Positive findings indicate antibodies to RBCs.
Coombs test
Increased values indicate longer clotting times. This is desirable
International normalized for anticoagulation therapy with Warfarin.
ratio (INR) 0.8 – 1.1 times the control value Decreased values indicate hypercoagulation and increased risk
for venous thromboembolic events.

Prothrombin time (PT) 11 – 12.5 sec Increased time indicates a possible deficiency of clotting factors
85% - 100% V and VII.
Decreased time may indicate a Vitamin K excess.

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