Anatomy and Physiology of The Human Body
Anatomy and Physiology of The Human Body
Human Body
Module 1
Cell
2
Module 1
Cell
Enjoy!
1. DNA replication occurs during the ______ stage of the cell cycle.
a. G1 c. S
b. G2 d. Prophase
2. What is the correct order of stages of mitosis
a. Prophase- metaphase-anaphase- telophase
b. Anaphase- prophase-telophase-metaphase
c. Metaphase-telophase-anaphase- prophase
d. Telophase-prophase-anaphase-metaphase
3. Genome is
a. The life cycle of the cell
b. The division of the cytoplasm
c. The entire collection of genes
d. A group of related species
At the end of mitosis, the daughter cells have
Half the number of chromosomes of the parent cell
a. The same number of chromosomes as the parent cell
b. Haploid chromosomes
c. 23 chromosomes
5. If an organism has a diploid chromosome number of 64, what wil be the
chromosome number of each daughter cell after mitosis?
a. 8 c. 42
b. 16 d. 64
6. Which stage in the cell cycle where begins to reorganize its contents in
preparation for mitosis.
a. G1 c. S
b. G2 d. Prophase
7. The cell cycle is usually regulated by
a. Cytoplasm c. Telophase
b. Cytokinesis d. Checkpoints
8. cells that have only one set of chromosomes
a. Diploid c. Genes
b. Haploid d. DNA
9. Stage where two diploid daughter cells are formed.
a. Cytoplasm c. Telophase
b. Cytokinesis d. Checkpoints
10. The two major phases in cell cycle
a. Anaphase and telophase c. Interphase and Cytokinesis
b. Interphase and Mitosis c. Interphase and Metaphase
Lesson 1
ell Theory
he microscopes we use today are much more advanced than those used in the 1600s by
T Antony van Leeuwenhoek, a Dutch shopkeeper who possessed great ability in lens crafts.
Despite the limitations of his now-old lenses, van Leeuwenhoek observed protista (a form of
single-celled organism) and sperm movements, which he collectively called "animalcules."
The experimental scientist Robert Hooke coined the word "cell" in a 1665 publication called
Micrographia for the box-like structures he found while observing cork tissue through a lens. Bacteria
and protozoa were discovered by van Leeuwenhoek in the 1670s. Later advances in lenses, construction
of microscopes, and staining techniques enabled many scientists to see components within cells.
By the late 1830s, botanist Matthias Schleiden and zoologist Theodor Schwann studied tissues
and proposed the unified theory of cells. The unified cell theory notes that: all living things are made up
of one or more cells; the cell is the basic unit of life; and from existing cells, new cells come. Later
Rudolf Virchow made significant contributions to the theory.
Spontaneous generation was suggested by Schleiden and Schwann as the mechanism for cell
origination but spontaneous generation (also called abiogenesis) was later disproved. Rudolf Virchow
said famously "Omnis cellula e cellula" ... "All cells derive only from the pre-existing cells.”
The generally accepted portions of the modern Cell Theory are as follows:
1. The cell is the fundamental unit of structure and function in living things.
2. All organisms are made up of one or more cells.
3. Cells arise from other cells through cellular division.
Atom
Answer Key on Page 16
Self-Test 1
Write true if the statement if correct and false if the statement is wrong.
1. Tissues are the smallest unit of matter.
2. Robert Hooke coined the statement ,”All cells derive only from the pre-existing cells”
3. Organ is a body structure anatomically distinct, consisting of two or more types of
tissues.
4. Rudolf Virchow proposed the unified theory of cells.
5. Molecule is form when two or more cells combine.
Lesson 2
Classification of Cell
Cells fall into one of two broad categories: prokaryotic and eukaryotic. The
predominantly single-celled organisms of the domains Bacteria and Archaea are classified as
prokaryotes (pro- = before; -karyon- = nucleus). Animal cells, plant cells, fungi, and protists are
eukaryotes (eu- = true).
Prokaryotic Cells
A prokaryotic cell is a basic, unicellular organism without a nucleus, or any other membrane-
bound organelle. As organized in the Three Domain System, prokaryotes include bacteria and archaeans.
Some prokaryotes, such as cyanobacteria, are photosynthetic organisms and are capable
of photosynthesis.
Many prokaryotes are extremophiles and can live and thrive in various types of extreme
environments including hydrothermal vents, hot springs, swamps, wetlands, and the guts of humans and
animals (Helicobacter pylori).
Prokaryotic bacteria can be found almost anywhere and are part of the human microbiota. They
live on your skin, in your body, and on everyday objects in your environment.
Prokaryotic cells are not as complex as eukaryotic cells. They have no true nucleus as
the DNA is not contained within a membrane or separated from the rest of the cell, but is coiled up in a
region of the cytoplasm called the nucleoid.
Prokaryotic organisms have varying cell shapes. The most common bacteria shapes are spherical,
rod-shaped, and spiral.
Using bacteria as our sample prokaryote, the following structures and organelles can be found
in bacterial cells:
Capsule-Found in some bacterial cells, this additional outer covering protects the cell when it is
engulfed by other organisms, assists in retaining moisture, and helps the cell adhere to surfaces and
nutrients.
Cell Wall-The cell wall is an outer covering that protects the bacterial cell and gives it shape.
Cytoplasm- Cytoplasm is a gel-like substance composed mainly of water that also contains enzymes,
salts, cell components, and various organic molecules.
Cell Membrane or Plasma Membrane-The cell membrane surrounds the cell's cytoplasm and
regulates the flow of substances in and out of the cell.
Pili (Pilus singular)- Hair-like structures on the surface of the cell that attach to other bacterial cells.
Shorter pili called fimbriae help bacteria attach to surfaces.
Flagella-Flagella are long, whip-like protrusions that aid in cellular locomotion.
Ribosomes-Ribosomes are cell structures responsible for protein production.
Plasmids-Plasmids are gene-carrying, circular DNA structures that are not involved in reproduction.
Nucleoid Region-Area of the cytoplasm that contains the single bacterial DNA molecule.
Prokaryotic cells lack organelles found in eukaryoitic cells such as mitochondria, endoplasmic
reticuli, and Golgi complexes. According to the Endosymbiotic Theory, eukaryotic organelles are
thought to have evolved from prokaryotic cells living in endosymbiotic relationships with one
another. Like plant cells, bacteria have a cell wall. Some bacteria also have a polysaccharide capsule
layer surrounding the cell wall. This is the layer where bacteria produce biofilm, a slimy substance that
helps bacterial colonies adhere to surfaces and to each other for protection against antibiotics, chemicals,
and other hazardous substances.
Similar to plants and algae, some prokaryotes also have photosynthetic pigments. These light-
absorbing pigments enable photosynthetic bacteria to obtain nutrition from light.
Eukaryotic Cells
A eukaryotic cell is a cell that has a membrane-bound nucleus and other membrane-bound
compartments or sacs, called organelles, which have specialized functions. The word eukaryotic means
“true kernel” or “true nucleus,” alluding to the presence of the membrane-bound nucleus in these cells.
The word “organelle” means “little organ,” and, as already mentioned, organelles have specialized
cellular functions, just as the organs of your body have specialized functions.
These organelles includes mitochondria (cellular energy exchangers), a Golgi
apparatus (secretory device), an endoplasmic reticulum (a canal-like system of membranes within the
cell), and lysosomes (digestive apparatus within many cell types). There are several exceptions to this,
however; for example, the absence of mitochondria and a nucleus in red blood cells and the lack of
mitochondria in the oxymonad Monocercomonoides species.
Fungal Cells
Like plant cells, fungal cells also have a cell wall, but their
cell wall is made of chitin (the same substance found in
insect exoskeletons). Some fungi have septa, which are
holes that allow organelles and cytoplasm to pass between them. This makes the
boundaries between different cells less clear.
Animal Cells
Animal cells do not have cell walls. Instead, they have only a
plasma membrane. The lack of a cell wall allows animal cells to
form many different shapes, and allows for the processes
of phagocytosis “cell eating” and pinocytosis “cell drinking” to
occur. Animal cells differ from plant cells in that they do not have
chloroplasts and have smaller vacuoles instead of a large central
vacuole.
Protozoa
Self-Test 2
Put () if the the cell contains the following parts. Mark () if it does not contain the
structure.
Eukaryotic Cell
Structure Prokaryotic Cell
Plant Cell Animal Cell
Cell Wall
Chloroplast
Central Vacuole
Centrioles
Cilia
Lysosomes
(Posttest)
Choose the letter(s) of the BEST ANSWER. Write your answers on a separate sheet
of paper
1. Which stage in the cell cycle where begins to reorganize its contents in
preparation for mitosis.
c. G1 c. S
d. G2 d. Prophase
2. The cell cycle is usually regulated by
c. Cytoplasm c. Telophase
d. Cytokinesis d. Checkpoints
3. cells that have only one set of chromosomes
c. Diploid c. Genes
d. Haploid d. DNA
4. Stage where two diploid daughter cells are formed.
c. Cytoplasm c. Telophase
d. Cytokinesis d. Checkpoints
5. The two major phases in cell cycle
1
a. Anaphase and telophase c. Interphase and Cytokinesis
b. Interphase and Mitosis c. Interphase and Metaphase
6. DNA replication occurs during the ______ stage of the cell cycle.
c. G1 c. S
d. G2 d. Prophase
7. What is the correct order of stages of mitosis
e. Prophase- metaphase-anaphase- telophase
f. Anaphase- prophase-telophase-metaphase
g. Metaphase-telophase-anaphase- prophase
h. Telophase-prophase-anaphase-metaphase
8. Genome is
e. The life cycle of the cell
f. The division of the cytoplasm
g. The entire collection of genes
h. A group of related species
9. At the end of mitosis, the daughter cells have
e. Half the number of chromosomes of the parent cell
f. The same number of chromosomes as the parent cell
g. Haploid chromosomes
h. 23 chromosomes
10. If an organism has a diploid chromosome number of 64, what wil be the
chromosome number of each daughter cell after mitosis?
c. 8 c. 42
d. 16 d. 64
2
Answers Key
Pretest Posttest
1. C 1. B
2. A 2. D
3. C 3. B
4. B 4. B
5. D 5. B
6. B 6. C
7. D 7. A
8. B 8. C
9. B 9. B
10.B 10.D
Activity 1.1
Genome is composed of DNA while gene is only a segment of
the DNA.
Self-Test 1.1
Activity 2.2
G1: first gap phase; the cell grows larger and organelles are copied.
S phase: DNA Replication.
G2: second gap phase; the cell grows more, makes proteins and
organelles, and begins to reorganize its contents in preparation for mitosis.
Mitosis (the M phase): cell divides its previously-copied DNA and
cytoplasm to make two new, identical daughter cells.
Self-Test 2.1
3
1. During Cell Division, cell has checkpoints in each stage to
determine if it can go to the next stage or be disregarded.
2. Interphase is the growth level of the cell. Mitosis is the
continue stage of cell cycle where duplicated chromosomes in
the interphase gains two new daughter cells.
Activity 3.1
1. B
2. D
3. C
4. A
5. D
4
Source:
https://www.thoughtco.com/prokaryotes-meaning-373369
https://www.livescience.com/65922-prokaryotic-vs-eukaryotic-cells.html
https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Book
%3A_General_Biology_(Boundless)/4%3A_Cell_Structure/4.1%3A_Studying_Cells/4.1C%3A_Cell_Theory
https://courses.lumenlearning.com/suny-ap1/chapter/structural-organization-of-the-human-body/
https://biologydictionary.net/eukaryotic-cell/
Anatomy and Physiology of the
Human Body
Module 2
Body Systems
Module 2
Body System
Enjoy!
1. DNA replication occurs during the ______ stage of the cell cycle.
a. G1 c. S
b. G2 d. Prophase
4. What is the correct order of stages of mitosis
a. Prophase- metaphase-anaphase- telophase
b. Anaphase- prophase-telophase-metaphase
c. Metaphase-telophase-anaphase- prophase
d. Telophase-prophase-anaphase-metaphase
5. Genome is
a. The life cycle of the cell
b. The division of the cytoplasm
c. The entire collection of genes
d. A group of related species
6. At the end of mitosis, the daughter cells have
d. Half the number of chromosomes of the parent cell
e. The same number of chromosomes as the parent cell
f. Haploid chromosomes
g. 23 chromosomes
6. If an organism has a diploid chromosome number of 64, what wil be the
chromosome number of each daughter cell after mitosis?
a. 8 c. 42
b. 16 d. 64
7. Which stage in the cell cycle where begins to reorganize its contents in
preparation for mitosis.
a. G1 c. S
b. G2 d. Prophase
7. The cell cycle is usually regulated by
a. Cytoplasm c. Telophase
b. Cytokinesis d. Checkpoints
8. cells that have only one set of chromosomes
a. Diploid c. Genes
b. Haploid d. DNA
9. Stage where two diploid daughter cells are formed.
a. Cytoplasm c. Telophase
b. Cytokinesis d. Checkpoints
10. The two major phases in cell cycle
a. Anaphase and telophase c. Interphase and Cytokinesis
b. Interphase and Mitosis c. Interphase and Metaphase
Lesson 1
Integumentary system
Word HUNT!
Self-Test 1
1. What is the importance of keeping or skin, hair and nails healthy?
_______________________________________________________________
_______________________________________________________________
2. In what ways can you help maintain integumentary system healthy?
_______________________________________________________________
_______________________________________________________________
Self-Test 2.1
Multiple Choice. In circle the letter of your answer.
1. Which bone is not part of the axial skeleton?
A. Skull B. pelvic girdle C. ribs D. vertebral column
2. What is the function of the bone marrow?
A. To manufacture platelets
B. Store fat cells
C. Provide structure to the bone
D. Serves as a wall
3. Which does not belong to the group?
A. Skull B. Ribcage C. Backbone D. femur
4. Which is not a function of the skeletal system?
A. Holds up the body. C. Protects parts inside the body.
B. Helps in our movement D. Helps regulate body temperature
5. Which joint is found in our neck?
A. Gliding B. Hinge C.Pivot D. Ball and socket
Fun Facts!
You have about 650 muscles in your body.
There are over 150 just in your head and neck!
Your muscles make up 50% of your body weight.
Your tireless heart beats more than 4500 times each hour.
Your muscle cells produce enough heat every day to boil almost 2 pints of water for an hour.
Smile! You've just used about 30 muscles. Muscles control your eyelids, nostrils and brow. They
work together to show the slightest change in your emotions.
Many of our organs consist of muscles which enable them to perform specific
functions. Relaxing muscles, and contracting. Muscle relaxation and contraction cause
body parts to move. Muscles help protect bones and internal organs such as the blood
vessels and kidneys. They also influence body shape. Muscle hold your organs in place
and also holds your bones together so that you can move. It helps you chew your food,
open and close your eyelids, pump your blood, allow you to move and exercise and
enable you to have good posture.
There are three types of muscles. First is the Skeletal Muscles. These are the
muscles we use to move around. They cover our skeleton and move our bones.
Sometimes they are called striped muscles because they come in long dark and light
bands of fibers and look striped. These muscles are voluntary because we control them
directly with signals from our brains. Most skeletal muscles run from one bone to
another We use them to run, jump, walk . One bone will move while other bone remains
fixed.
Next is the Smooth Muscles. Smooth muscles are special muscles that don't
connect to bones, but control organs within our body. These muscles work without us
having to think about them. These can be found in the digestive system: stomach,
esophagus, intestines, control digestion. And in our respiratory system: lungs,
diaphragm, control breathing. Also, in urinary system: bladder, controls urination.
And the Cardiac Muscle. This is a special muscle that pumps our heart and
blood through our body. It is only found in the heart. It works automatically but under
constant nervous system and chemical control. Contractions of the heart muscle pump
blood throughout the body and account for the heartbeat.
Tendons connect muscles to bones. Tendons help form a connection between
soft contracting muscle cells to hard bone cells. Ligaments connect bones to other
bones to form joints. Muscle Memory happens when we practice an action over and
over again, we get what is called muscle memory. It allows us to become more skilled at
certain activities such as sports and music. As we practice, our muscles tune
themselves to become more precise in their motions and to do exactly what our brain
wants them to do. So, remember, practice makes perfect!
Self-Test 2.1
1. What are the functions of the muscular system?
______________________________________________________________________
______________________________________________________________________
2. What are similarities and differences of the three types of muscle tissues?
______________________________________________________________________
______________________________________________________________________
Answer Key on
Lesson 4
Digestive System
Digestion starts in the mouth. The teeth grinds the food while the saliva moistens
the food and contains an enzyme called salivary amylase. The tongue then pushes the
food towards your throat as to swallow. By this time your larynx moves upward to flat
your epiglottis. The epiglottis closes the opening of your trachea so that the food will
not enter your lungs. The food then goes to the esophagus, a straight muscular tube.
Here the food is move through a wavy motion called peristalsis. The food then enters
the stomach, a “J” shaped muscular sac that serves as a blender or mixer. It contains
hydrochloric acid that helps breakdown the food. The food digested in the stomach
becomes a mixed liquid called chyme. That then passes through the small intestine. The
small intestines absorbs the nutrients and vitamins are absorb in this part. The
undigested food then passes through the large intestine or colon. Here most of the
water are absorb the waste then hardens and solidifies. The waste is then push towards
the rectum, an expanded portion of the large intestine and stays there until it is excreted
as feces through the anus.
What will you do?
Activity 2
Supply the needed enzyme in each stage of the digestive tract.
Self-Test 2.1
1. What is the role of minerals in maintaining good health?
________________________________________________________________
________________________________________________________________.
Answer Key on
Lesson 5
Excretory System
The excretory system is a close partner of both the endocrine and circulatory
system. The connection to the circulatory system is obvious. Blood circulating through
the body traverses one of the two kidneys. Urea, uric acid, and salt must be separated
from the blood and much of the oxygen will be added to the body.
The endocrine system is the excretory system 's principal master. When compound
and fluid levels are tracked, the work of the kidneys must be continuously altered to
provide the cells with the best interior environment. If you drink too much water, they
release hormones that allow more urine output. If you're dehydrated it will produce less
urine. The kidneys are also tied to the endocrine system at the top of each kidney, with
the adrenal gland position. Adrenaline is released into your body by the adrenals.
Good to Know Facts!
Besides taking out trash from your body, your kidneys also help balances the vitamins, minerals, proteins
and fat content in the blood, so that your body can perform all regular tasks very easily.
The excretory system is attached to the digestive system to provide a passage for the release of chemicals
which the body doesn’t need.
Various organs help the body dispose of the waste foods safely in your right and left kidneys.
One of the most interesting facts about the excretory system is that the human bladder can hold up to 400 ml
of urine.
Urine is often diluted and poured in potted plants in gardens because urine contains considerable amounts
of urea which serves as a wonderful source of nitrogen for plants.
https://bodytomy.com/excretory-system-facts
Self-Test 2.1
1. Name three ways you can take good care of your excretory system.
______________________________________________________________
______________________________________________________________
______________________________________________________________
______________________________________________________________
______________________________________________________________
Answer Key on
Lesson 6
Respiratory System
Human respiratory system is a series of organs which are responsible for oxygen intake and carbon dioxide
expulsion. The respiratory system's primary organs are the lungs, which perform this exchange of gases while we
breathe.
The lungs function in tandem with the circulatory system to pump oxygen-rich blood to all body cells.
According to the American Lung Association, the blood collects carbon dioxide and other waste products, and
transports them back to the lungs where they are pumped out of the body when we exhale. The human body needs
oxygen to sustain itself. After only about five minutes without oxygen, brain cells begin dying, according to
the National Institute of Neurological Disorders and Stroke, which can lead to brain damage and ultimately death.
Respiratory Tract
Upper respiratory tract:
Composed of the nose, the pharynx, and
the larynx, the organs of the upper respiratory
tract are located outside the chest cavity.
Lower respiratory tract: Composed of the trachea, the lungs, and all segments of the bronchial
tree (including the alveoli), the organs of the lower respiratory tract are located inside the chest
cavity.
Trachea: Located just below the larynx, the trachea is the main airway to the lungs.
Lungs: Together the lungs form one of the body’s largest organs. They’re responsible
for providing oxygen to capillaries and exhaling carbon dioxide.
Bronchi: The bronchi branch from the trachea into each lung and create the network of
intricate passages that supply the lungs with air.
Diaphragm: The diaphragm is the main respiratory muscle that contracts and relaxes to
allow air into the lungs.
How exactly do we breathe?
Materials
Clear plastic water/pop bottle (20 oz. size)
Large balloon or a piece of plastic from a trash bag or shopping bag (about 7 x 7 inch square)
Small balloon
Rubber band
Scissors
Masking tape
Procedure:
1. Use scissors. Start at the slit and cut off the bottom of the bottle.
2. Push the end of the small balloon through the mouth of the bottle.
3. Stretch the mouth of the balloon over the mouth of the bottle.
4. Place the mouth of the large balloon over the bottom, open end of the bottle. Tape it securely to the bottle.
1. Hold the bottle and push in and pull out on the handle. Watch the small balloon inside the bottle.
What do you observe?
2. While moving the handle in and out, hold the opening of the bottle near your face. What do you
feel?
3. Describe what happens to the balloon, inside the bottle, as you move the handle in and out. Explain
your observations.
Self-Test 2.1
1. Explain what happens to your rib cage when you breathe in and out.
______________________________________________________________________
______________________________________________________________________
______________________________________________________________________
______________________________________________________________________
Answer Key on
Lesson 7
Circulatory System
The circulatory system is made up of blood vessels that carry blood away from and towards the
heart. Arteries carry blood away from the heart and veins carry blood back to the heart.
The circulatory system carries oxygen, nutrients, and hormones to cells, and removes waste
products, like carbon dioxide. These roadways travel in one direction only, to keep things going
where they should.
The heart has four chambers — two on top and two on bottom:
The two bottom chambers are the right ventricle and the left ventricle. These pump blood
out of the heart. A wall called the interventricular septum is between the two ventricles.
The two top chambers are the right atrium and the left atrium. They receive the blood
entering the heart. A wall called the interatrial septum is between the atria.
Two valves also separate the ventricles from the large blood vessels that carry blood
leaving the heart:
The pulmonic valve is between the right ventricle and the pulmonary artery, which
carries blood to the lungs. The aortic valve is between the left ventricle and the aorta, which
carries blood to the body.
PULMONARY CIRCULATION
The blood that the vena cava vein takes to the heart is full of carbon dioxide. It
has much less oxygen than (systemic) arterial blood. The right side of the heart pushes
the venous blood into the pulmonary artery. The pulmonary artery takes blood to the
lungs. In the lungs, the blood goes through the pulmonary capillary bed. (The capillaries
that are in the lungs). Here it gets more oxygen. It also drops off carbon dioxide. (This is
the opposite of what happens in capillary beds in the rest of the body. In the systemic
circulation blood drops off oxygen and picks up carbon dioxide).
After the pulmonary capillary bed, the blood goes to the pulmonary veins.
This pulmonary venous blood now is full of oxygen. The pulmonary veins take blood to
the left side of the heart. Then the blood goes to the systemic circulation again.
SYSTEMIC CIRCULATION
Next, blood that returns to the heart has picked up lots of oxygen from the lungs.
So it can now go out to the body. The aorta is a big artery that leaves the heart carrying
this oxygenated blood. Branches off of the aorta send blood to the muscles of the heart
itself, as well as all other parts of the body. Like a tree, the branches gets smaller and
smaller as they get farther from the aorta.
Capillaries then lead into small veins. Small veins lead to larger and larger veins
as the blood approaches the heart. Valves in the veins keep blood flowing in the correct
direction. Two large veins that lead into the heart are the superior vena cava and inferior
vena cava. (The terms superior and inferior don't mean that one vein is better than the
other, but that they're located above and below the heart.)
Once the blood is back in the heart, it needs to re-enter the pulmonary circulation
and go back to the lungs to drop off the carbon dioxide and pick up more oxygen.
Self-Test 2.1
1. Explain what happens to your rib cage when you breathe in and out.
______________________________________________________________________
______________________________________________________________________
______________________________________________________________________
______________________________________________________________________
Answer Key on
Lesson 8
Lymphatic System
The lymphatic system is a vital part of the immune system, along with the thymus,
bone marrow, spleen, tonsils, appendix, and Peyer patches in the small intestine.
Like the venous system, the lymphatic system
transports fluids throughout the body. The
lymphatic system consists of
Thin-walled lymphatic vessels
Lymph nodes
Two collecting ducts
In the body, lymphatic vessels are wider than
capillaries (the smallest blood vessels linking
arteries and veins), and others are smaller than the
smallest veins. Most lymphatic vessels have valves
that flow in one direction (toward the heart) like
those in the veins to keep the lymph that can clot.
Lymphatic vessels drain fluid from tissue throughout
the body, called lymph.
Lymph begins as a fluid that diffuses into the
space between cells through the very thin walls of
capillaries. Some of the fluid is reabsorbed into the
capillaries, and the remainder is drained into the
lymphatic vessels, which gradually return it to the
veins. Lymph also contains a large number of other
substances including
Proteins, minerals, nutrients and other
substances that power the tissues
Damaged cells, cancer cells and foreign
particles (such as bacteria and viruses)
that may have entered fluids in the tissue
The lymph nodes are lymph collection
centres. All of the lymph moves through strategically
located lymph nodes that filter out of the lymph compromised cells, cancer cells and
foreign particles. Lymph nodes also contain specialized white blood cells (e.g.,
lymphocytes and macrophages) intended to envelop and destroy damaged cells, cancer
cells, infectious organisms, and foreign particles. Consequently, important lymphatic
system functions are to remove damaged cells from the body and to provide protection
against the spread of infection and cancer.
All substances transported by the lymph pass through at least one lymph node,
where foreign substances can be filtered out and destroyed before fluid is returned to
the bloodstream. In the lymph nodes, white blood cells can collect, interact with each
other and with antigens, and generate immune responses to foreign substances. Lymph
nodes contain a mesh of tissue that is tightly packed with B cells, T cells, dendritic cells,
and macrophages. Harmful microorganisms are filtered through the mesh, then
identified and attacked by B cells and T cells.
The lymphatic vessels, device that brings lymph all over the body, drain into
collecting ducts which empty their contents into the two subclavian veins below the
collarbones. These veins join to form the superior vena cava, the great vein that drains
blood into the heart from the upper body.
Self-Test 2.1
1. The lymphatic system consists of all the following except:
A) blood B) lymph nodes
C) lymphatic vessels D) lymph
2. Which of the following applies to the thoracic duct?
A) it drains the entire body above the diaphragm
B) it empties its contents into the subclavian vein
C) it carries blood into the lymphatic system
D) it arises in the vessels of the brain
3. Which of the following is not likely to be found in the lymph?
A) red blood cells B) protein molecules
C) microorganisms D) macrophages
4. What is the purpose of antibodies?
A. To pump lymph through the vessels B. To create lymph
C.To fight infection D. To remove old red blood cells
5. The lymphatic structure that closely parallell veins are called?
A. Capillaries B. Lymph C. Lymph Vessels
Answer Key on
Lesson 9
Nervous System
The Brain
The brain is the center of the nervous system. It governs most of your body’s
functions. It is found inside the head and is protected by the skull. The brain is the organ
which receives, processes and stores information from inside and outside the body. It
decides what to do with the received information and sends signals to the body to react,
decide or move.
The largest part of the brain is the cerebrum. It receives, stores and recalls all
the information the body picks up. Cognitive processes such as thinking, memorizing
and decision making occur in the outer gray part of the cerebrum, which is called the
cerebral cortex. Cortex means “covering.” The inner white part of the cerebrum relays
electrical signals to other parts of the brain.
The cerebellum is a highly folded mass of nerve tissue located just below the
cerebrum. It controls muscle coordination and balance. When you play basketball, the
cerebellum helps you in making your moves. Imagine a drunken man walking. He sways
in an unbalanced, uncoordinated way. That is how you would be if your cerebellum were
not working.
The brainstem is the hind part of the brain. It holds the medulla oblongata and
the pons. The medulla oblongata or medulla transmits signals between the spinal cord
and the brain. It also controls autonomic or involuntary functions such as heartbeat and
breathing. The pons is partly made up of tracts that connect the spinal cord with higher
brain levels. It also contains cell groups that transfer information from the cerebrum to
the cerebellum.
The spinal cord is the downward extension of the brain. The brain has to have a
way to receive signals and send commands to the different parts of the body, doesn’t it?
The spinal cord serves this purpose. It allows impulses to travel to and from the brain.
Without the spinal cord, the brain could not receive nor send information. Without the
spinal cord, the brain would lose its ability to control the body.
From the spinal cord, bundles of nerve cells branch off and through them the
central nervous system sends commands to different parts of the body. Through these
nerve cells, pass the sensory signals that bring information from inside and outside the
body to be processed in the brain. This system of nerve cells that branch off the brain
and the spinal cord comprise the peripheral nervous system.
The brain, through the peripheral nervous system, sends signals to the body to
react to certain conditions. An action that is willed or controlled by your thoughts is
called a voluntary action. Jumping, running and singing are voluntary actions. You run
only when you want to run and sing only when you want to sing. You can stop anytime
or continue doing something for a long time. There is a conscious effort in doing the
activity. These movements are being actively controlled by the brain.
Nerves are bundles of fibers (axons) from neurons and which are held together
by connective tissue. Look at the diagram of the neuron below.
The nerve cell or neuron is the basic unit of the nervous system. Its shape helps
it carry out its function. A neuron consists of the following parts:
♦ The fibers that branch out from the nerve cell are the dendrites. These fibers pick up
information from the receptors. The information received by the dendrites is then carried
to the cell body or soma in the form of an electrical signal. The cell body contains the
nucleus of the cell as well as other structures that help keep the cell alive.
♦ The electrical signal continues along the cell body and moves to a single, long fiber
called an axon. From the axon, the electrical signal is transmitted to another nerve cell.
Between the axon of one cell and the dendrite of another is a small gap called synapse.
When the electrical signal reaches the tip of the axon of one cell, a chemical spills into
the synapse. This chemical receives and carries the electrical signal to the dendrite of
the next nerve cell.
Self-Test 2.1
Fill in the blanks with the correct word or group of words.
1. There are _________ major divisions of the nervous system.
2. The central nervous system is composed of the __________ and the
_______________.
3. The nerves that branch off the brain and the spinal cord make up the
______________ nervous system.
4. The __________________ is the seat of human intelligence.
5. The _____________________ forms the outermost portion of the cerebrum.
Lesson 10
Endocrine System
The endocrine system is a set of glands which produce hormones that, among other
things, regulate metabolism , growth and development, tissue function , sexual function,
reproduction, sleep, and mood.
What is a gland?
A gland is an organ that makes and puts out hormones that do a specific job in your
body. Endocrine glands release the substances they make into your bloodstream.
Functions of the Endocrine System
Your endocrine system:
Self-Test 2.1
1. Choose the pair of hormones that have agonistic effects on blood sugar levels:
A.) Calcitonin and PTH
B.) Adrenalin and Glucagon
C.) Glucagon and Glucose
D.) ADH and Aldosterone
2. Hormones may consist of all the following except:
A) steroids B) proteins C) carbohydrates D) amines
3. The two major portions of the adrenal gland are the:
A) medulla and cortex B) exocrine and endocrine C) renal and subrenal
D) posterior and anterior portions
4. The proper functioning of the body's immune system depends in part on the
activity of the:
A) thyroid gland B) thymus gland C) parathyroid gland D) adrenal
gland
5. Chemical messengers secreted by ductless glands are called___________
a) Lymph
b) Platelets
c) Plasma
d) Hormones
Lesson 11
Reproductive System
Let’s Summarize
(Posttest)
Choose the letter(s) of the BEST ANSWER. Write your answers on a separate
sheet of paper
1. Which stage in the cell cycle where begins to reorganize its contents in
preparation for mitosis.
c. G1 c. S
d. G2 d. Prophase
2. The cell cycle is usually regulated by
c. Cytoplasm c. Telophase
d. Cytokinesis d. Checkpoints
3. cells that have only one set of chromosomes
c. Diploid c. Genes
d. Haploid d. DNA
4. Stage where two diploid daughter cells are formed.
c. Cytoplasm c. Telophase
d. Cytokinesis d. Checkpoints
5. The two major phases in cell cycle
1
a. Anaphase and telophase c. Interphase and Cytokinesis
b. Interphase and Mitosis c. Interphase and Metaphase
6. DNA replication occurs during the ______ stage of the cell cycle.
c. G1 c. S
d. G2 d. Prophase
11. What is the correct order of stages of mitosis
e. Prophase- metaphase-anaphase- telophase
f. Anaphase- prophase-telophase-metaphase
g. Metaphase-telophase-anaphase- prophase
h. Telophase-prophase-anaphase-metaphase
12. Genome is
e. The life cycle of the cell
f. The division of the cytoplasm
g. The entire collection of genes
h. A group of related species
13. At the end of mitosis, the daughter cells have
e. Half the number of chromosomes of the parent cell
f. The same number of chromosomes as the parent cell
g. Haploid chromosomes
h. 23 chromosomes
14. If an organism has a diploid chromosome number of 64, what wil be the
chromosome number of each daughter cell after mitosis?
c. 8 c. 42
d. 16 d. 64
2
Answers Key
Pretest Posttest
1. C 1. B
2. A 2. D
3. C 3. B
4. B 4. B
5. D 5. B
6. B 6. C
7. D 7. A
8. B 8. C
9. B 9. B
10.B 10.D
Activity 1.1
Genome is composed of DNA while gene is only a segment of the
DNA.
Self-Test 1.1
Activity 2.2
G1: first gap phase; the cell grows larger and organelles are copied.
T phase: DNA Replication.
G2: second gap phase; the cell grows more, makes proteins and organelles,
and begins to reorganize its contents in preparation for mitosis. Mitosis (the
M phase): cell divides its previously-copied DNA
Which is a possible characteristic of a eukaryotic cell?
A. Having a cell wall made of cellulose
B. Having a cell wall made of chitin
C. Having no cell wall
D. All of the above are seen in eukaryotic cells
http://www.britannica.com/EBchecked/topic/360838/mammal/
51715/Excretory-system
https://www.livescience.com/22616-respiratory-system.html
https://www.britannica.com/science/human-respiratory-system
https://www.healthline.com/human-body-maps/respiratory-system#2
kiddle.co/Exchange_of_gases
https://www.lung.ca/lung-health/lung-info/how-your-lungs-work
https://www.britannica.com/science/circulatory-system/Body-fluids
https://www.merckmanuals.com/home/heart-and-blood-vessel-disorders/lymphatic-disorders/overview-of-the-
lymphatic-system
https://www.livescience.com/26496-endocrine-system.html
https://www.webmd.com/diabetes/endocrine-system-facts
https://www.webmd.com/diabetes/endocrine-system-facts
drink 8 glasses of water a day.
Avoid eating salty foods
Exercise