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Prep 10 Postlab

Sulfur ointment is used as a parasiticide and keratolytic to treat skin conditions like psoriasis and seborrhea. It contains 9.5-10.5% precipitated sulfur as the active ingredient, which is first levigated with mineral oil and then incorporated into a white ointment base. The finished ointment is a yellow, homogeneous solid with a smooth yet slightly stiff and greasy texture that is non-water washable. It must be packaged in plastic ointment jars and preserved in well-closed containers to avoid coalescence or rancidity.

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Kate Mendoza
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364 views

Prep 10 Postlab

Sulfur ointment is used as a parasiticide and keratolytic to treat skin conditions like psoriasis and seborrhea. It contains 9.5-10.5% precipitated sulfur as the active ingredient, which is first levigated with mineral oil and then incorporated into a white ointment base. The finished ointment is a yellow, homogeneous solid with a smooth yet slightly stiff and greasy texture that is non-water washable. It must be packaged in plastic ointment jars and preserved in well-closed containers to avoid coalescence or rancidity.

Uploaded by

Kate Mendoza
Copyright
© © All Rights Reserved
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Sulfur Ointment Plasters

➢ Solid or semisolid adhesive masses


Official Title Sulfur ointment, USP spread on a backing of paper, fabric,
moleskin, or plastic.
Category Parasiticide ➢ Provide prolonged contact at the site.
Synonyms Precipitated sulfur ointment, Glycerogelatin
Lae sulfuris ointment ➢ Plastic masses containing 15% gelatin,
40% glycerin, 35% H2O and an added
Uses Parasiticide, Keratolytic, used
10% medicinal substance such as
for treatment of skin diseases zinc oxide.
such as psoriasis and ➢ Applied to the skin for the long term,
seborrhea remaining in place for weeks.
Official Sulfur ointment contains not
Definition less than 9.5% and not more Cataplasms
➢ An ancient dosage form; soft moist
than 10.5% sulfur
mass of metal, herbs, seeds, etc.
➢ Usually applied in hot cloth.
➢ Has a gruel like consistency.
REVIEW OF BASIC CONCEPTS ➢ Also called Poultices
➢ Intended to localize infectious material
Creams
in the body to count as counter
➢ Semisolid preparation containing one
irritants.
or more medicinal agents dissolved
➢ Materials used tended to be absorptive
or dispersed in either a water-in-oil
emulsion or an oil-in-water emulsion or
Powders
in other water washable bases.
➢ Intimate mixture of dry, finely,
➢ Preferred over ointments for their
divided drugs
ease of spreading and removal.
Dusting powders
Pastes
➢ Powders for external use are termed
➢ Semisolid preparations intended for
application to the skin like ointments .
but are stiffer as they contain a large
Dressings
proportion of a solid material.
➢ External application resembling
➢ Because of their stiffness, they are
ointments used for covering or
not suited for application to hairy
protection.
parts of the body.
➢ Topical antibacterial products come
in this form.
Gels
➢ Contraceptives
➢ Semisolid preparations consisting of
dispersions of small or large molecules ➢ Come in the form of jellies, creams or
aerosols that immobilize spermatozoa.
in an aqueous liquid vehicle rendered
jelly-like with the addition of a gelling ➢ Contains buffers to counter the
pH change cause by vaginal
agent.
fluids
➢ Other name: Jellies
INGREDIENTS AND USES
coalescence,
bleeding, drying out
Ingredient Amount Uses
and rancidity
Precipitated sulfur 100 g API
Label For external use only
Mineral oil 100 g Levigating
agent Container Plastic ointment jar

Packaging Req. Preserve in well-closed


White ointment 800 g Hydrocarbon
container and avoid
base
prolonged exposure to
excessive heat
PROCEDURE

1. Levigate 1 g sulfur with the 1


g Mineral Oil to a smooth
paste
- RFIS: Sulfur is first
LEVIGATED with mineral
oil to aid in
INCORPORATION
2. Then incorporate with 8
g White Ointment.
- RFIS: Geometric dilution
should be practiced when
incorporating to ensure
uniform DISTRIBUTION
and dosage.

QUALITY CONTROL & PACKAGING

Appearance Yellow homogeneous


solid

Texture-surface Smooth, non-gritty

Texture spatula Smooth, non-gritty


spread

Overall feel Greasy


greasiness

Overall feel Non-water washable


water-washability

Overall feel stiffness Slightly stiff

Overall feel solid Moderate amount


content of solids present

Physical stability No change in


consistency,

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