®

MCS +:
Multicomponent Collection
System
The only true multicomponent system
 Applications
Component donations
 Platelets
 Red blood cells
 Plasma
 All blood component combinations

Patient treatments
 Stem cells
 Plasma exchange
 Autologous red blood cells
 Therapeutic cell removal

2 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Multicomponent collection

MCS + + automated Platelet Collection

+ automated Red Cell Collection
+ automated Plasma Collection
+ combinations of all above
+ therapeutic applications

3 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 MCS®+: Multicomponent Collection System
Key advantages
 Lightweight at 27.5 kg
 Reliable
 Good product quality
 Real multicomponent device
 Fast set-up and tear-down
 No secondary component processing
 Minimal operator involvement and time
 Quiet device

4 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Applications
 Plasma is collected to be transfused(FFP):
 Substitution of coagulation factors and plasma proteins in cases of massive
bleeding, transplantation, clotting disorders, burns
 Plasma is collected for industrial fractionation (PPP):
 Most often plasma is fractionated and sold to pharmaceutical companies as raw
material for manufacture into biopharmaceuticals.
 Platelets are collected to be transfused:
 Patients undergoing surgery, chemotherapy
 Hemophilia, bleeding disorders
 Red Blood cells are collected to be transfused:
 Severe hemorrhage (surgery, emergency)
 Anemia, Thalassemia
 Stem cells are collected to be transfused:
 Leukemia treatments, repopulate the whole bone marrow and grow new blood
cells after chemotherapy
 Plasma exchange is done on a patient:
 Removal and replacement of plasma with donor plasma or other fluids in order to
treat a variety of diseases eg. Guillain-Barré syndrome or Hyperviscosity
syndrome

5 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Plasma applications
Plasma Collection protocols
 PPP&FFP, Platelets poor Plasma & Fresh Frozen Plasma
 Therapeutic plasma collection with closed sets (623E, 622HS, 623HS)
 Fractionation plasma collection with pre-connected or bundled sets
(627, 792, 782, 782HS-P, 792P, 625B, 625HS, 690, 692, 699, SC690,
SC692, 620, 620E)
 Utilization of standard BMB or HS core bowl.
 Optional Saline compensation

6 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Disposables
Unbundled sets  The customer creates his own set
(Commercial plasma collection):
Needle
Donor harness
Centrifuge bowl
Collection part (bottle or bag(s))

Donor harness Bowl Bag

7 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Disposables
Pre-connected sets  Sets are connected but not „closed“
(PPP or FFP):

8 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Disposables
Closed sets  Sets are connected and closed: They contain
bacterial filters on the connections
(Fresh frozen plasma collection):

9 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Platelet applications
Platelets Collection protocols
 LDP, Leukodepleted platelets (994CF-E)
 Standard Platelets collected in plasma
 Concurrent PPP plasma collection and
Saline compensation
 Continuous Platelet Leukocyte filtration

 LDPRBC, Leukodepleted platelets and Red Cells Collection (946FF)

 Standard Platelets collected in plasma
 1 unit of RBC re-suspended in SAG-M
 Concurrent PPP plasma collection and Saline compensation
 Continuous Platelet Leukocyte filtration
 Manual Red Cells leukocyte filtration

10 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Platelet applications
Platelets Collection protocols
 UPP, Universal platelets protocol
 Standard Platelets collected in plasma (997CF-E)
 Concentrated Platelets collected in additive (999F-E)
 Concurrent RBC re-suspended in SAG-M (949FF-E)
 Concurrent PPP plasma collection
 Optional Saline compensation (997CF-E)
 Continuous Platelet Leukocyte filtration
 Manual Red Cells leukocyte filtration (949FF-E)

11 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Disposables
Disposable sets for platelets collections: 99XCF-E-BA BA  Bacterial
sampling system
9  MCS+ disposable set E  Europe

9  Platelets application CF  Continuous

filtration for platelets

12 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Red Cells applications
Red Blood Cells Collection protocols
 SDR&TAE, Single Donor Red Blood Cells & Therapeutic
Autologous Erythropheresis.
SDR
 2 units of Buffy Coat removed RBC (942)
 2 units of Leukodepleted RBC (948F)
TAE
 3 units of buffy coat removed RBC (944)

 Red Cells re-suspended in SAG-M

 Optional Saline compensation

13 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Red Cells applications
Red Blood Cells and Plasma Collection protocol
 RBCP+, Red Blood Cells & Plasma
 1 unit of Buffy Coat removed RBC and 2 units of plasma (941)
 1 unit of Leukodepleted RBC and 2 units of plasma (947F)

 Red Cells re-suspended in SAG-M

 Optional Saline compensation

14 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Disposables
Disposable sets for red cell collections: 94XFF
F  Filter for platelets
9  MCS+ disposable set

4 Red cell applications F Filter for red cells

15 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Therapeutic applications
Therapeutic protocol
 TPE, Therapeutic Plasma Exchange protocol (980E, 981E)
 Extract plasma from a patient
 Substitution fluid monitored by the device
 2 type of bowls 125ml, 225ml

 PBSC, Peripheral Blood Stem Cells (970E, 971E)

 Stem Cells (PBSC): collects a mononuclear cell concentrate (MNC)
used for peripheral stem cell transplantations.
 Therapeutic Platelet Reductions (TPR): reduce the platelet count of
patients with abnormally high platelet counts
 Therapeutic Leukocyte Reductions (TLR): reduce the white cell count
of patients with abnormally high white cell.
 Optional Saline compensation

16 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Disposables
Disposable sets for therapy: 9YXE
E International sets
9  MCS+ disposable set

7 or 8 Therapy application 0 or 1 0 for 225ml bowl

1 for 125 ml bowl

17 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)

 Questions

18 © 2012 Haemonetics Corp. COL-COPY-000487-IE(AA)