SAFETY DATA

SHEET
1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifiers
Product Name Calcium (Ca)
Cat. No. CA590
1.2 Relevant identified uses of the For in vitro diagnostic use only.
substance or mixture and uses Do not pipette by mouth. Handle laboratory reagents in accordance with Good
advised against. Laboratory Practice.
1.3 Details of the supplier of the safety data sheet
Company Randox Laboratories Ltd., 55 Diamond Road, Crumlin, Co. Antrim, United Kingdom,
BT29 4QY
Telephone +44 (0) 28 9442 2413
Fax +44 (0) 28 9445 2912
E-mail Address [email protected]
Website www.randox.com
1.4 Emergency Telephone Number
Emergency Phone No. +44 (0) 28 9442 2413
(GMT, English spoken, Mon - Fri. 08.40-17.20)

2. HAZARDS IDENTIFICATION
2.1 Classification of the substance or mixture
2.1.1 Regulation (EC) No. 1272/2008 R1. Buffer
(CLP) Skin Irrit. 2: H315, Eye Irrit. 2: H319, Aquatic Chronic 3: H412
CAL. Standard, R2. Chromogen and R3. EDTA
This product contains no hazardous chemicals in reportable quantities according to
Regulation (EC) No. 1272/2008 (CLP).
2.1.2 Directive 67/548/EEC & R1. Buffer
Directive 1999/45/EC Xi: R36/38, R52/53
Symbols: Xi: Irritant
CAL. Standard, R2. Chromogen and R3. EDTA
This product contains no hazardous chemicals in reportable quantities according to
EU Directives 67/548/EEC or 1999/45/EC.
2.2 Label Elements
Labelling according to Regulation
(EC) No. 1272/2008 (CLP)
Product Name Calcium (Ca)
Hazard Pictogram (s) R1. Buffer

CAL. Standard, R2. Chromogen and R3. EDTA

No pictogram
Signal Word (s) R1. Buffer: Warning,
CAL. Standard, R2. Chromogen and R3. EDTA: No Signal Word

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Hazard Statement (s) R1. Buffer
Skin Irrit. 2: H315 - Causes skin irritation
Eye Irrit. 2: H319 - Causes serious eye irritation
Aquatic Chronic 3: H412 - Harmful to aquatic life with long lasting effects
CAL. Standard, R2. Chromogen and R3. EDTA
No hazard statement
Precautionary Statement (s) R1. Buffer
P302+P352 - IF ON SKIN: Wash with plenty of water.
P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313 - If skin irritation occurs: Get medical advice/attention
P337+P313 - If eye irritation persists: Get medical advice/attention
P333+P313 - If skin irritation or rash occurs: Get medical advice/attention.
CAL. Standard, R2. Chromogen and R3. EDTA
No precautionary statements
2.3 Other Hazards None

3. COMPOSITION/INFORMATION ON INGREDIENTS
3.1 Substances – Not applicable
3.2 Mixtures
EC Classification No. 1272/2008

Component Name Hazardous Chemical Concentration (w/v) CAS No. REACH Reg. No. Hazard Statement(s)

Eye Irrit. 2 H319

R1. Buffer 2-Amino-2-methyl- 30 - 40% 124-68-5 Not Applicable Skin Irrit. 2: H315
propanol Aquatic Chronic 3:
H412
EC Classification No. 67/548/EEC

Component Name Hazardous Chemical Concentration (w/v) CAS No. REACH Reg. No. EC Classification and
Risk Phrase(s)

R1. Buffer 2-Amino-2-methyl- 30 - 40% 124-68-5 Not Applicable Xi; R36/38,

propanol R52/53

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4. FIRST AID MEASURES
4.1 Description of first aid measures

Inhalation If inhaled, move victim to fresh air, rest and maintain a half-upright position. Use
artificial respiration if necessary. Immediately seek medical attention.
Skin Contact If skin contact occurs, remove contaminated clothes, rinse skin with plenty of cold
water or shower. Seek medical attention.
Eye Contact If eye contact occurs, first rinse with plenty of cold water for several minutes, then
immediately seek medical attention.
Ingestion If ingested, rinse mouth. Do not induce vomiting. Give plenty of water to drink.
Immediately seek medical attention.
4.2 Most important symptoms and Not determined
effects, both acute and delayed
4.3 Indication of any immediate medical Call an internal person trained in First Aid if available, or contact a physician.
attention and special treatment
needed

5. FIREFIGHTING MEASURES
5.1 Extinguishing media As appropriate for the surrounding fire
5.2 Special hazards arising from the May emit toxic fumes under fire conditions.
substance or mixture
5.3 Advice for firefighters Wear self-contained breathing apparatus and protective clothing to prevent contact
with skin and eyes.

6. ACCIDENTAL RELEASE MEASURES

6.1 Personal precautions, protective Ensure adequate ventilation. Wear appropriate Personal Protective Equipment
equipment and emergency e.g. laboratory coat, gloves, safety glasses and mask.
procedures
6.2 Environmental Precautions Not determined
6.3 Methods and materials for Use appropriate spill absorbent kit as instructed by the manufacturer. Alternatively
containment and cleaning up mop up with an absorbent material and hold for waste disposal.
6.4 Reference to other sections Refer to section 8 & 13

7. HANDLING AND STORAGE

7.1 Precautions for safe handling Wear personal protective equipment (refer to section 8.2.2). Wash thoroughly after
handling. Do not use if skin is cut or scratched. Avoid contact with eyes, skin and
clothing. Do not eat, drink or smoke when using this product.
7.2 Conditions for safe storage, Store at temperatures and conditions as indicated on the product label.
including any incompatibilities
7.3 Specific end use (s) For in vitro diagnostic use only.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

8.1 Control Parameters Not determined
8.2 Exposure Controls

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8.2.1 Appropriate engineering controls Ensure adequate ventilation.
8.2.2 Personal protective equipment
Eye/Face Protection Approved safety glasses
Hand Protection Standard laboratory rubber or latex gloves
Skin Protection A laboratory coat is recommended
Respiratory Protection None
8.2.3 Environmental Exposure Controls Not determined

9. PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on basic physical and chemical properties
Appearance Liquid - all components

Colour Colourless (CAL. Standard, R1. Buffer, R3. EDTA)

Light Green (R2. Chromogen)
Odour Not determined

Odour threshold (ppm) Not determined

pH Value 10.7 (R1. Buffer)

4 (R3. EDTA)
Melting point / Freezing point Not determined
Initial boiling point and boiling range Not determined
Flash point (oC) Not determined
Evaporation rate Not determined
Flammability (solid, gas) Not determined
Upper/lower flammability or explosive Not determined
limits
Vapour pressure Not determined
Vapour Density Not determined
Relative Density Not determined
Solubility (ies) Not determined
Partition coefficient: (n-octanol/water) Not determined
Auto ignition temperature (C) Not determined
Decomposition temperature (oC) Not determined
Viscosity (mPa.s) Not determined
Explosive properties Not determined
Oxidising properties Not determined
9.2 Other information None

10. STABILITY AND REACTIVITY

10.1 Reactivity Not determined
10.2 Chemical Stability Stable under recommended storage conditions
10.3 Possibility of hazardous reactions Not determined

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10.4 Conditions to avoid Not determined
10.5 Incompatible materials Not determined
10.6 Hazardous decomposition Not determined
products

11. TOXICOLOGICAL INFORMATION

11.1 Information on toxicological
effects
Acute toxicity Not determined
Ingestion Not determined
Inhalation Not determined
Skin Contact Not determined
Eye Contact Not determined
Skin corrosion/irritation Not determined
Serious eye damage/eye irritation Not determined
Respiratory or skin sensitization Not determined
Germ cell mutagenicity Not determined
Carcinogenicity Not determined
Reproductive toxicity Not determined
STOT – Single exposure Not determined
STOT- Repeated exposure Not determined
Aspiration hazard Not determined
11.2 Other information Not determined

12. ECOLOGICAL INFORMATION

12.1 Toxicity Not determined
12.2 Persistence and degradability Not determined
12.3 Bioaccumulative potential Not determined
12.4 Mobility in soil Not determined
12.5 Results of PBT and vPvB Not determined
assessment
12.6 Other adverse effects Not determined

13. DISPOSAL CONSIDERATIONS

13.1 Waste Treatment Methods Each disposal facility must determine proper disposal methods of the substance or
mixture and any contaminated packaging to comply with Local and National
Environment Regulations. Refer to section 6.
13.2 Additional Information Not determined

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14. TRANSPORT INFORMATION
14.1 UN Number Not classified as hazardous for transport
14.2 UN Proper Shipping Name Not determined
14.3 Transport hazard class (es) Not applicable
14.4 Packing Group Not applicable
14.5 Environmental Hazards Not determined
14.6 Special Precautions for User Refer to section 7
14.7 Transport in bulk according to Not applicable
Annex II of MARPOL73/78 and the
IBC Code

15. REGULATORY INFORMATION

This safety data sheet complies with the requirements of EU Regulations 1907/2006 (REACH), 1272/2008 (CLP) & 453/2010.
15.1 Safety, health and environmental Not determined
regulations/legislation specific for
the substance or mixture
15.2 Chemical Safety Assessments CSA has not been carried out

16. OTHER INFORMATION

Hazard Class, Hazard Statements and Risk Phrases Description from Sections 2 & 3

R36/38 - Irritating to eyes and skin

R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment

The information provided herein is believed to be correct as of the date hereof but does not purport to be all-inclusive and shall be
used only as a guide. The information present in this document is based on the present state of our knowledge and is applicable to
the product with regard to appropriate safety precautions. The recipient of our products is responsible for observing any National
Laws and guidelines applicable.

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REVISION A REVISION (0)
22 April 2016 5 June 2015
According to EC Regulations 1907/2006 (REACH), 1272/2008 (CLP) & 453/2010