Spring 2021: COURSE OUTLINE BS PROGRAM SEMESTER 6TH

BS PROGRAM 6th

Punjab College Pattoki

Prof. Dr. M Athar Sab GCUF Coordinator

Course Outline of 6th Semester BS CHEMISTRY

BS CHEMISTRY 6TH

CHM-502 Inorganic Chemistry – III 4(3-1)

CHM-502 Inorganic Chemistry-III

1. Chemistry of Non-Aqueous Solvents Classification of solvents. Type of reactions in non-

aqueous solvents. Physical and chemical properties of solvents. Study of reactions in liquid NH3,

HF, SO2, BrF3, CH3COOH and HCN. Reactions in molten salt system.

2. Pi-Acceptor Ligands Class of ligands. Metal carbonyls, molecular structure, localized bonding

(EAN rule, 18 electron rule). Delocalized bonding (Wades rule), spectroscopic evidence of

bonding situation. Chemical properties of metal-carbonyls (carbonylate anions, carbonyl

hydrides and carbonyl halides). Metal nitrosyls and their derivatives. Applications of metal

carbonyls and their derivatives to catalysis and organic synthesis.

3. Kinetics and mechanism of inorganic reactions Rate law, Stationary state approximation,

Labile and inert complexes. Mechanism of substitution reactions in octahedral

complexes(hydrolysis reactions, anation reactions, reactions of substituted ligand and redox

reactions). Thermodynamic and kinetic stability.

Half life. CHM- 502 Practical’s

1. Estimation Of Anions (Any four) Chloride/Phospate; Chloride/Nitrate; Bromide/Nitrate;

Iodide/Nitrate; Borate/ Acetate; Oxalate/ Chloride; Sulphate/Phosphate

2. KIO3 Titrations (Any two)

3. Gravimetric Estimations: Estimations of Ba2+ ; Oxalate ions.

Books Recommended:

1. J. E. Huheey, “Inorganic Chemistry Principles of Structure and Reactivity” 2 nd Ed. Harper

and Row Publishers (1978).

2. J. D. Lee, “Concise Inorganic Chemistry” 5 th Ed. Chapman and Hall (1996).

3. K. M. Mackay, R. A. Mackay, W. Henderson, “Introduction to Modern Inorganic Chemistry” 5

th Ed. Stanley Thornes (Publishers) Ltd. (1996).

4. G. L. Miessler, A. T. Donald, “Inorganic Chemistry”. 2nd Ed, Prentice-Hall Prentice-Hall

International, Inc. (1991). BS (Hons) Chemistry Session 2018-22

5. F. A. Cotton, G. Wilkinson, “Advance Inorganic Chemistry”, 5th Ed, John Wiley & Sons, Inc.

(1988).

6. F. A. Cotton, G. Wilkinson, C. A. Murillo, M. Bockhmann, “Advanced Inorganic Chemistry” 6

th Ed, John Wiley & Sons, Inc. USA (1999).

7. A. K. Holliday, A. G. Massey, “Inorganic Chemistry in Non-Aqueous Solvents”, 6th Ed.,

Pergamon Press. (1985).

CHM-504 Organic Chemistry-III

Aliphatic nucleophilic substitution and Elimination reactions Aliphatic nucleophilic substitution

reactions Meachanisms and study of SN1, SN2, SN1, SN2, mechanism; neighbouring group

participationintra molecular displacement by neighbouring oxygen, nitrogen, sulphur and

halogen; The effects of the substrate structure, entering group, leaving group and reaction

medium on the mechanisms and rates of substitution reactions. Elimination

ReactionsMechanisms study of E1, E1cB and E2 mechanisms; attacking base, leaving group and
COURSE OUTLINE BS PROGRAM SEMESTER 6TH

the reaction medium on the rates and mechanisms of elimination reactions; competition between

elimination andsubstitution reactions. Aromatic Substitution reactions Electrophilic substitution

Aromaticity; mechanisms of substitution; orientation sulfonation, Friedel-Crafts reactions, diazo-

coupling, formylation and carboxylation. Nucleophilic substitutionMechanisms-Study of SNAr,

SN1 and benzyne mechanisms; The effects of substrate structure, leaving group and the attacking

nucleophile on the rates of substitution reactions. Named Organic Reactions Cannizzaro reaction,

Perkin reaction, Michael reaction, Claisen-Schmidt reaction, Darzens Glycidic Ester reaction,

Stobbe reaction, Mannich reaction, Wittig reaction, Ene reaction and Reformatsky reaction,

Diels-Alder reaction. CHM-504 Practicals

Organic Synthesis at least four experiments involving two step synthesis Estimation of Amide

and Carboxyl groups, Phenol and other functional groups. Determination of Saponification value

and acid value in oil.

Books Recommended:

1. F. A. Carey, R. J. Sundberg, “Advanced Organic Chemistry (Part B: Reactions and

Synthesis)”, 3 rd Ed, Plenum Press, New York, USA (1990).

2. B. K. Carpenter, “Determination of Organic Reaction Mechanisms, “John Wiley & Sons, Inc.

(1984).

3. G. R. Chatwal, “Reaction Mechanism and Reagents in Organic Chemistry”, 1 st Ed., Himalaya

Publishing House (1987).

4. J. Fuhrhop, G. Penzlin, “Organic Synthesis Concepts, Methods, Starting Materials”, 2 nd Ed.,

Weinheim Germany (1983).

5. R. K. Mackie, D. M. Smith, “Guide book to Organic Synthesis”, Longman Group Ltd. (1982).

BS (Hons) Chemistry Session 2018-22

6. J. March, “Advanced Organic Chemistry Reactions, Mechanisms and Structure”, 4 th Ed, John

Wiley & Sons, Inc; USA (1992).

7. A. Streitwieser, C. H.H. Cock, “Introduction to Organic Chemistry”, 3 rd Ed, Macmillan

Publishing Company (1989).

8. P. Sykes, “A Guide Book to Mechanism in Organic Chemistry”, 6 th Ed, Longman Group Ltd.

(1986).

9. A. L. Vogel, “Elementary Practical Organic Chemistry Part III: Quantitative Organic

Analysis”, 1 st Ed., Longman Group Ltd (1958).

CHM 506 Physical Chemistry III

Electrochemistry Theory of metallic conduction, electrode potential, electrochemical cell,

electrolysis and related issues, liquid junction potential electron transfer reactions, rate of charge

transfer reaction, cell potential and thermodynamics, and Nernst equation, Voltammetry, fuel

cells. Corrosion and its prevention. Ion in aqueous solution, ionic activity and Debye Huckel

Theory. Quantum Chemistry and Spectroscopy Eigen functions and eigenvalues, Schrödinger

wave equation and its applications, Hamiltonian operator, Simple harmonic oscillator. Rigid

rator, vibrator, Quantum numbers. Symmetry Elements Introduction, Coordinate System,

Symmetry operations and symmetry Elements, The Symmetry Point Groups.

CHM-506 Practicals

 Determination of molecular weight of a polymer by viscosity method

 Precipitation value of electrolytes

 Measurement of IR spectra of simple compound and their interpretation

 Measurement of cyclic voltammogram of an organic compound and its interpretation

 Determination of dipole moment of an organic liquid

 Determination of percentage composition of KMnO4 / K2Cr2O7 in a given solution by

spectroscopy.

 Stoichiometry of a complex in solution by jobs method

 Evaluation of pKa value of indicator by spectrometric method

Books Recommended:

1. F. Cotton, Albert “Chemical Applications of Groups Theory”, 1st Ed, Interscience Publishers

(1963). BS (Hons) Chemistry Session 2018-22

2. G. W. King, “Spectroscopy and Molecular Structure”, 1st Ed, Rinehart and Winston (1964).

3. J. Albery, “Electrode Kinetics”, 2nd Ed, Clarendon, Oxford, (1975).

4. O. M. J. Bockris, A. K. N. Reddy, “Modern Electrochemistry” 2nd Ed, Vol. I and 2, Plenum

Press, New York, USA (1970).

5. D. F. Micheal, “Elements of Quantum Mechanics” 2nd Ed., Oxford University Press, USA

(2005).

6. H. H. Lowell, “Group Theory and Symmetry in Chemistry” 1st Ed, McGraw Hill Book

Company (1969).

7. D. H. Whiffen, “Spectroscopy” 1st Ed, Longmans Green and Co.: London, (1966).

CHM-508 Analytical Chemistry-III

Spectroscopy, Theory and principals of Spectroscopy, Lambert-Beer‟s Law and its limitations,

Single and double beam spectrophotometers, sources of light (lamp and lasers),

monochromators, photomultiplier tubes, detectors, diode array and charged coupled devices,

applications of UV-Vis spectrophotometer in natural product research, pharmaceutical industry,

separation process, enzyme essay study, clinical studies, microbiology. Applications of IR, NMR

and Mass spectrophotometer in research & development and quality control process.

Practical’s

1. Qualitative and quantitative analysis by UV/Visible Spectroscopy

2. Identification of functional groups of organic compounds by IR spectroscopy

3. Identification of organic compounds using available and accessible spectroscopic techniques

4. Sample preparation for various molecular spectroscopic techniques; IR, FTIR, MS

5. Visit of Hi-Tech Lab and practical demonstration of molecular spectroscopic techniques; IR,

FTIR, MS

Reference Books:

1. Christian, G.D. Analytical Chemistry, 6th ed., John-Wiley & Sons, New York, (2004).

2. Harris, D.C. Quantitative Chemical Analysis, 8th ed., W. H. Freeman and Company, New

York, (2011).

3. Skoog, D. A., West, P.M., Holler, F.J. and Crouch, S. R., Fundamentals of Analytical

Chemistry, 9th ed., Cengage Learning, (2013).

4. Braun, R.D. Introduction to instrumental Analysis, International student Edition, (1985).

CHM-510 Environmental Chemistry

Introduction, General principle and Techniques. Soil, sludge, sediment and dust analysis.

Analysis of plant Material, Analysis of Atmospheric samples, Analysis of Water, determination

of toxic organic Chemistry. Toxicity of heavy metals. Biological indicators, Green Chemistry,

Echo toxicology.

Recommended Books:
COURSE OUTLINE BS PROGRAM SEMESTER 6TH

1. B. B. Kebbekus, S. Mitra “Environmental Chemical Analysis”, 1st Ed., Blackie Academic &

Professional, New York, USA (1998).

2. D. Barcelo, “Environmental analysis: Techniques, Applications and Quality Assurance”,

Volume 13, Elsevier B.V., Netherland (1993).

3. P. Patnaik, “Handbook of Environmental Analysis”, 2nd Ed, CRC Press, Taylor and Francis

Group, UK (2010).