Hypoxia: Lori Holmes
Hypoxia: Lori Holmes
TREATMENTS
Hydration/Humidification
Airway suctioning
O2 therapy
Intubation
Nutritional Support
Transfusion/Reperfusion
Sedation for anxiety
Bronchodilators
Corticosteroids(airway inflammation)
Lasix(decrease pulmonary congestion)
IV antibiotics
Manage diabetes
Amputation(localized with cell death)
Stents/catherization
Concept Map-Hypoxia
9/4/2013
Lori Holmes
Risk Factors
Labs/Tests
Pathophysiology
Treatments
1. What is the pathophysiological explanation of cellular swelling during the early stages of cell injury?
According to authors McCance and Heuther, “Hypoxia injury occur when mitochondrial oxygenation has been stopped and
this decreases ATP production. Lack of ATP levels cause the plasma membrane’s sodium-potassium pump and sodium-
calcium exchange to fail, which leads to an intracellular accumulation of sodium and calcium and diffusion of potassium out of
the cell. Sodium and water enter the cell freely, and cellular swelling happens” (McCance & Huether, 2006).
References
McCance, K., & Huether, S. (2006). Altered cellular and tissue biology. In K. McCance, & S. Huether, Pathophysiology: The Biologic
basis for disease in adults and children (5th ed., pp. 51-85). St. Louis: Elsevier/Mosby.
Sharon Lewis, R. M.-B. (2007). Medical-surgical nursing. St. Louis: Mosby/Elsevier.
Concept Map-Hypoxia
9/4/2013
Lori Holmes