06 Infectious Disease Epidemiology
06 Infectious Disease Epidemiology
I. Definitions
A. Infectious disease
B. Communicable disease
C. Contagious disease
II. Phases of Communicable Disease
A. Pre-pathogenic phase
B. Pathogenic phase
III. Requirements for successful agent invasion
d. Portal of exit
5. Factors affecting communicability of bacteria
a. Site of lesion of infected host
b. Size of the inoculum
c. Chance of contact with bacterial strain
d. Survival capacity in immune species
e. Ability to survive outside animal body
f. Ability to multiply and survive in intermediate host/vector
g. Size of reservoir infection
B. Host
1. Stages of disease
a. Stage of susceptibility
b. Stage of subclinical disease (pre-symptomatic disease)
c. Stage of clinical disease
d. Stage of disability or death
2. Defense mechanism of the host
a. Specific anatomical defences
b. Immunity
c. Resistance tolerance
d. Allergy
e. State of nutrition
3. Generation time VS Incubation period
4. Kinds of host
a. Definitive host
b. Reservoir host
c. Intermediate host
d. Paratenic host
e. Dead-end host or incidental host
f. Host of predilection
g. Amplifying host
C. Environment
1. Categories
a. Physical
1) Climate
2) Geographic
b. Biologic
c. Socioeconomic
2. Factors determining reaction of community to disease agent
a. Herd immunity
b. Exposure or contact rate
c. Chance/probability of contact between source and susceptible