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06 Infectious Disease Epidemiology

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0% found this document useful (0 votes)
14 views4 pages

06 Infectious Disease Epidemiology

dasdas
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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INFECTIOUS DISEASE EPIDEMIOLOGY

I. Definitions
A. Infectious disease
B. Communicable disease
C. Contagious disease
II. Phases of Communicable Disease
A. Pre-pathogenic phase
B. Pathogenic phase
III. Requirements for successful agent invasion

IV. Elements of a communicable disease


A. Agent
1. Classification (physical, mechanical, chemical, nutrient, biologic)
2. Characteristics of a living agent
a. Inherent
1) Physical make up
2) Chemical component
3) Antigenic characteristics
b. Biologic
1) Viability
2) Growth requirements
3) Host range
3. Characteristics of agents directly related to man
a. Infectivity
b. Pathogenicity
c. Virulence
d. Immunogenicity
e. Antigenicity
4. Characteristics of agent directly related to the environment
a. Reservoir of infection
b. Sources of infection
*Carrier (inapparent throughout, incubatory, convalescent, chronic)
c. Mode of transmission (direct and indirect)

d. Portal of exit
5. Factors affecting communicability of bacteria
a. Site of lesion of infected host
b. Size of the inoculum
c. Chance of contact with bacterial strain
d. Survival capacity in immune species
e. Ability to survive outside animal body
f. Ability to multiply and survive in intermediate host/vector
g. Size of reservoir infection
B. Host
1. Stages of disease
a. Stage of susceptibility
b. Stage of subclinical disease (pre-symptomatic disease)
c. Stage of clinical disease
d. Stage of disability or death
2. Defense mechanism of the host
a. Specific anatomical defences
b. Immunity
c. Resistance tolerance
d. Allergy
e. State of nutrition
3. Generation time VS Incubation period
4. Kinds of host
a. Definitive host
b. Reservoir host
c. Intermediate host
d. Paratenic host
e. Dead-end host or incidental host
f. Host of predilection
g. Amplifying host
C. Environment
1. Categories
a. Physical
1) Climate
2) Geographic
b. Biologic
c. Socioeconomic
2. Factors determining reaction of community to disease agent
a. Herd immunity
b. Exposure or contact rate
c. Chance/probability of contact between source and susceptible

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