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Aripiprazole

Aripiprazole is an antipsychotic drug used to treat schizophrenia. It works as a partial agonist at dopamine and serotonin receptors. Common side effects include weight gain, headache, insomnia, and vomiting. Nurses monitor patients for behavioral changes, side effects like extrapyramidal symptoms and tardive dyskinesia, as well as metabolic changes like blood glucose levels. Patients are advised to avoid alcohol and tasks requiring alertness until drug effects are established and to report worsening symptoms or changes in behavior.

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Krisianne Mae Lorenzo Francisco
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6K views

Aripiprazole

Aripiprazole is an antipsychotic drug used to treat schizophrenia. It works as a partial agonist at dopamine and serotonin receptors. Common side effects include weight gain, headache, insomnia, and vomiting. Nurses monitor patients for behavioral changes, side effects like extrapyramidal symptoms and tardive dyskinesia, as well as metabolic changes like blood glucose levels. Patients are advised to avoid alcohol and tasks requiring alertness until drug effects are established and to report worsening symptoms or changes in behavior.

Uploaded by

Krisianne Mae Lorenzo Francisco
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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ROUTE,

NAME OF MECHANISM NURSING


DOSAGE, AND INDICATION CONTRAINDICATION SIDE EFFECT
DRUG OF ACTION RESPONSIBILITIES
FREQUENCY
Generic name: PO: Initially, 10– Provides partial Treatment of Hypersensitivity to Frequent (11%– Baseline assessment
Aripiprazole 15 mg once daily. agonist activity at schizophrenia. Aripiprazole 5%): Assess behavior,
May increase up Dopamine (D2, Weight gain, appearance, emotional
Brand name: to30 mg/day. D3) and serotonin headache, status, response to
Aristada Titrate dose at (5-HT1A) insomnia, environment, speech
minimum of 2-wk receptors and vomiting. pattern, thought content.
Classification: intervals antagonist activity Occasional Correct dehydration,
Dopamine agonist, at serotonin (5- (4%–3%): hypovolemia. Assess for
Antipsychotic HT2A) receptors. Light-headedness, suicidal tendencies.
agent Improves nausea, akathisia, Question history (or
symptoms drowsiness. family history) of
associated with Rare (2% or diabetes. Obtain serum
schizophrenia. less): blood glucose level.
Blurred vision,
constipation, Intervention/Evaluation
asthenia (loss of Periodically monitor
strength, energy), weight. Monitor for
anxiety, fever, extrapyramidal
rash, cough, symptoms (abnormal
rhinitis, movement), tardive
orthostatic dyskinesia (protrusion of
hypotension. tongue, puffing of
cheeks,
chewing/puckering of the
mouth). Periodically
monitor B/P, pulse.
Monitor serum blood
glucose levels during
therapy. Assess for
therapeutic response
(greater interest in
surroundings, improved
self-care, increased
ability to concentrate,
relaxed facial
expression).

PO
• Give without regard to
food. Orally
Disintegrating Tablet
• Remove tablet, place
entire tablet on tongue.
• Do not break, split
tablet.
• May give without
liquid.

Patient/family teaching

• Avoid alcohol.
• Avoid tasks that
require alertness, motor
skills until response to
drug is established.
• Report worsening
depression, suicidal
ideation, unusual changes
in behavior,
extrapyramidal effects.

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