BETHLEHM SCHOOL, HARAR

BIOLOGY WORK SHEETS FOR GRADE 12,2021G.C

FOR TUTORIAL CLASS ONLY.

Directions: Choose the correct answer from the given alternatives.

______1. One of the following would be harder to see under the ordinary light
microscope that is more likely to be available in school laboratory ?
A. Nucleus C. A mitochondria
B. A bacteria D. A ribosome
_____2. Which of the following cell types can be rich in lysosome ?
A. Phagocytic cells C. Red blood
cells
B. Nerve cells D. Muscle cells
_____3. If the red blood cells shrink when placed in a certain solution, what is the
strength of the solution relative to the strength of the protoplasm of the
cells?
A. Hypotonic C.Isotonic
B. Isotonic D. Hypertonic
_____ 4. Most cells membrane are primarily composed of which compound?
A. Protein and lipids C. Chitin and starch
B. DNA and ATP D. Nucleotide and
cellulose
____ 5. Which of the following paired organelles are membrane bounded ?
A. Ribosomes and peroxisomes C. Mitochondaria and
ribosome
B. Chloroplast and ribosome D. Chloroplast and
mitochodria
____6. What will happen if human red blood cells are kept in a hypotonic solution?
A. Loose water by osmosis and shrink

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 B. Loose water by osmosis and turgid.
C. Take in water by osmosis,swell and burst.
D. Take in water by osmosis,swell and remain turgid.
____ 7. Which of the following features is an important function of Golgi apparatus ?
A. Protein synthesis
B. Packaging of protein for out of the cell.
C. Removing debris from the cell.
D. Storage of waste materials not needed by the cell.
____8. If the size of the cell increase which one of the following gets smaller ?
A. The volume of the cell
B. The surface area of the cell.
C. The surface area to volume ratio of the cell.
D. Volume to surface area ratio of the cell.
____ 9. Inf the suspension of the mixture of cellular organelles is spun in centrifuge,
which organelle settles to the bottom first ?
A. Mitochondria C. Chloroplast
B. Nuclei D. Ribosome
____ 10. According to the fluid-mosaic model of the plasma membrane, what does
the word “ mosaic” refer to ?
A. The arrangement of the protein
B. The bilayer neture of the membrane
C. The hydrophobic properties of fatty acids.
D. The movement of the phospholipids.
____ 11. What is the substance that helps to keep the biological membrane in a fluid
state?
A. Phospholipids C. water
B. Cholestrol D. waxes
____12. Which of the following is NOT true about mitochondaria and Chloroplast ?
A. Both transduce energy. C. Both contain chlorophyll
B. Both have double membrane D. Both contain nucleic
acid

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___ 13.Among the following biologist who contribute to the cell theory, identifies the
one who stated the cell ‘ a cell can arise only from another cell like it.’
A. Robert Hoke C.Mattias scheleden
B. Theodor schawan D. Rudolf Virchow
____ 14. Which of the following modes of transport is used by the cell to move
substance against their concentration gradients ?
A. Osmosis C. Facilitated
diffusion
B. Simple diffusion D. Active transport
____ 15. What does it mean when a biologist express the cell membrane as a unit
membrane?
A. Cell is covered by a single membrane
B. A membrane is only one lipid layer thick.
C. All cell have essentially similar membrane.
D. A membrane is covered by a single layer of protein.
____ 16. Which of the following cellular structure is possessed by all cells?
A. Cell membrane C. Cell wall
B. Nucleus D. Golgi
apparatus
_____17. Which of the following mechanism moves digested amino acids and
glucose across the plasma membrane of the cell lining the wall of small
intestine?
A. Osmosis C. Facilitated diffusion
B.Simple diffusion D. Active transport
____18. If a cell fail to clear it’s cellular debris, which one of the following organelles
is most likely NOT functioning?
A. Nucleus C. mitochondaria
B. Lysosome D. Endoplasmic
reticulum
_____ 19.Which component of plasma membrane mis matched with its role?
A. Glycolipid--cell to cell recognition.
B. Antigin--identity marker.

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 C. Cholestrol--reduce fluidity of the membrane.
D. Channel protein--used to move larger molecule.
_____20. Which of the following belong to Eukaryotic cell?
A. Bacteria C. Amoeba
B. Blue green algea D. Virus
____21. The organelle that helps in penetration of sperm into egg during fertilization
is?
A. Nucleus C. Peroxisome
B. Mitochondria D. Lysosame.
____22. An organell which is NOT found in animal cell is?
A. Plastid C. Cell membrane
B. Ribosome D. Mitochondaria.
____23. Which of the following transport system is known as “ cell eating”?
A. Exocytosis C. Phagocytosis
B. Pinocytosis D. Osmosis
____24. Which of the following is due to loss of water from the cell?
A. Bursting of cell C. Osmosis
B. High turgor pressure D.Wilting
____25. How do you define osmosis in a semi-permeable membrane?
A. The diffusion of water from a more concentrated solution to a less
conc.one.
B. The diffusion of water from a less conc. Solution to a more conc. One.
C. The diffusion of solute from a more conc. Solution to a less conc. One
D. The diffusion of solute from a less conc. Solution to a more conc. One.
____26. Plasmolysis takes place when a cell is kept in;
A. Isotonic environment C. distilled water
B. Hypertonic environment D. Hypotonic
environment
____27. In the cell the major enzyme involved in the synthesis of a ATP are found
in?
A.Golgi body C. Nuclei

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 B. Mitochondria D.Centrioles
Questions 28-30 are based on the following statement.
“ A blood cell having an internal salt concentration of 0.9% was immersed
in a 10% salt solution”
____28. The concentration of water is;
A. Greater in the immediate environment than in the cell
B. Equal inside and outside the cell.
C. Not important to the size of the cell.
D. Greater inside the cell than outside.
___29. the cell would probably;
A. Expand and burst open content C. retains its normalsize
B. Shrink down D. loses its salt.
___30. Which cell structure is responsible for the above activity?
A. Nucleus C. vacuole
B. Cytoplasm D. Cell membrane

___31,Which one of the following cellular forms did Robert Hooke observe
under his crude microscope?
A. Bacteria C. Yeast
B. Protozoa D. Empty cell wall
___32,Which of the following is the common characteristic of all enzymes?
A. They act inside the cell C. They require cofactors
B. They are proteins D. They operate at any PH
___33,For a biological detergent to effectively remove oily and greasy dirt,
which of the following enzyme should it contain?
A. Cellulase C. Amylase
B. Protease D. Lipase
___34Which one of the following eukaryotic cell organelles was a living cell
before eukaryotic cell evolved?
A. Nucleus C. Chloroplast
B. Ribosome D. Nucleolus
___35,Choose the organism that belongs to the eukaryotes?
A. Bacteria C. Amoeba
B. Blue-green algae D. Virus

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___36,In the case of enzymatic chemical reactions, what do you call the substance that is acted
up on by an enzyme?

A. Substrate C. Coenzyme
B. Vitamin D. Cofactor
___37,Which one of the following is the main constituent of biological
membranes?
A. Glycoprotein C. Cholesterol
B. Glycolipid D. Phospholipids
___38,The main component of plant cell wall is _____________.

A. Starch C.Chitin
D.Peptido Glycan.
B.Cellouse

___39,One of the following molecules is the building units of an enzyme

molecule.
A. Glucose C. Amino acids
B. Fatty acids D. Nucleotides
___40 Which of the following classes of enzymes digest carbohydrates?
A. Amylase C. Proteases
B. Lipase D. Nucleases
___41,To which class of enzymes do the digestive enzymes belong?
A. Esterases C. Hydrolases
B. Transferases D. Isomerases
___42,Competitive enzyme inhibition differ from non-competitive enzyme
inhibition in that in competitive inhibition.
A. As we increase the substrate concentration the inhibitor molecules will
be replaced by the substrate at the active site
B. An increase substrate concentration does not affect the reaction rate
C. The inhibitor molecules occupies the active site of an enzyme
permanently
D. The inhibitor molecules occupies the allosteric site
___43,All of the following chemical acts as irreversible inhibitors except:-
A. Penicillin C. Ibuprofen
B. Aspirin D. Organophosphate
❑
___44,In the chemical reaction X E1 Y E 2 Z , where E ∧E are enzymes and
1 2
→ →

when concentration of the product Z❑ increases and stops the action of E1,
then such kind of enzyme regulation is referred to as:

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 A. Feed back control C. Allosteric regulation
B. End product inhibition D. Irreversible regulation
___45,Which one do you think is the most abundant digestive enzyme in an
Ethiopian poor farmer?
A. Fat digestive enzyme C. Carbohydrate enzyme
B. Protease enzyme D. Lipid digestive enzyme
___46,The reason why there are so many different kinds of enzyme in a cell
is:
A. Enzyme can be used over and over again
B. Enzyme are specific in action
C. Their activity can be affected by high temperature
D. Because it speed up a chemical reaction
___47,The coenzyme known as NAD and FAD respectively derived from a
vitamin called?
A. Thiamine and Niacin C. Ascrobic acid and Niacin
B. Niacin and Riboflavin D. Calciferol and Thiamine
___48,Which of the following do viruses share with cells?
A. Cell wall C. Nucleic acid
B. Cytoplasm D. Protoplasm

_______49.Which one of the following options represents the correct catabolic pathway of
the given respiratory substrates?

A. Proteins ammonia amino acid pyruvate TCA

B. Nucleic acids amino acids nucleotides acetyl-CoA TCA
C. Polysaccharides glucose acetyl-CoA pyruvate TCA
D. Lipids fatty acids acetyl-CoA TCA

_______50.Identify the organic molecule which is correctly paired with its function.

A. Cellulose - component of cell membrane

B. Triglycerides – respiratory substrate
C. Phospholipids – control metabolism
D. Glycogen – formation of microfibrills

_______51.Which part of phospholipids is considered as hydrophobic region?

A. Glycerol head C. Hydrocarbon tails

B. Carboxyl group D. Phosphate group

_______52.In a structure of amylase molecule that contains one hundred α- glucose

monomers, how many α -1, 4- glycosidic bonds are formed?

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 A. 200 C. 100
B. 50 D. 99

_______53.Unbalanced hydrogen bonding at the surface of the water is responsible for high

A. Specific heat capacity of water

B. Density of water in its liquid form
C. Latent heat of vaporization of water
D. Surface tension of water

_______54.Which one of the following options contains only a group of organic biochemical
molecules?

A. Lactic acid , hydrochloric acid , sucrose, water and ATP

B. Fatty acid , glycine ,DNA, maltose and triglyceride
C. ATP, deoxyribose , sulphuric acid , lactic acid and amino acid
D. Ribose , methane , fatty acid , lactose and sodium chloride

_______55.In the structural arrangement of cell membrane, the organic molecules which
serve as the structural backbone and prevent uncontrolled movement of water soluble
materials are

A. Carbohydrates. C. Peripheral proteins

B. Lipid bilayers D. Cholesterols

_______56.If α- giucose reacts with fructose molecule in a condensation reaction, what will
be the chemical formula of the disaccharide formed in this reaction?

A. C12H22O11 C. C12H24O12
B. C10H20O10 D. C6H12O6

_______57.`Which organic molecules in our body have functions as antigens and antibodies
of the immune system?

A. Lipids C. Proteins
B. Nucleic acids D. Carbohydrates

_______58.One benefit of water related to its high specific heat capacity is its importance

A. To support the weight of some insects while they walk on it

B. For the transport of blood cells around the circulatory system
C. For the normal functioning of enzymes in living cells
D. To move particles inside the cell more easily

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_______59.Which molecule of the plasma membrane contains carbohydrate chains and
allows identification of the cell by the immune system?

A. Glycoproteins C. Peripheral proteins

B. Channel proteins D. Integral proteins

_______60.What is the role of cholesterol in the cell membrane? To

A. Serve as signals to other membrane of cells

B. Make the membrane selectively permeable
C. Maintain the membrane fluidity
D. Anchor integral proteins with the membrane

_______61.Which of these elements is known to have less than 10% occurrence in many
cells?

A. Carbon B. Hydrogen C. Nitrogen D. Oxygen

_______62.One of the following is a non- carbohydrate molecule.

A. Starch B. Cellulose C. Glycogen D. Collagen

_______63.When glucose molecules are joined by α- linkage which of the following

carbohydrate is obtained?

A. Lactose B. Starch C. Glycogen D. Cellulose

_______64.Through which of the following methods can blood be separated into its cellular
and fluid parts?

A. Separating funnel C. Centrifuging

B. Fractional distillation D. Simple distillation

Prepared by Nesredin.T