Hypoxemia
Hypoxemia
Hypoxemia, or low blood oxygen, describes a lower than normal level of oxygen in your blood.
In order to function properly, your body needs a constant level of oxygen circulating in the blood
to cells and tissues. When this level of oxygen falls below a certain amount, hypoxemia occurs
and you may experience shortness of breath.
Your doctor determines whether you have hypoxemia by measuring your blood oxygen level —
the amount of oxygen traveling in your arteries. Your blood oxygen can be measured by testing a
sample of blood from an artery.
An approximate blood oxygen level can also be determined using a pulse oximeter — a small
device that clips on your finger. Though the pulse oximeter actually measures the saturation of
oxygen in your blood, the results are often used as an estimate of blood oxygen levels. Normal
pulse oximeter readings range from 95 to 100 percent, under most circumstances. Values under
90 percent are considered low.
Causes
• Airway obstruction
• Anemia
• ARDS (acute respiratory distress syndrome)
• Certain medications, such as narcotics and anesthetics, which depress breathing
• Congenital heart disease — heart defects that are present at birth
• COPD (chronic obstructive pulmonary disease)
• Emphysema
• High altitudes
• Interstitial lung disease
• Pneumonia
• Pneumothorax
• Pulmonary edema
• Pulmonary embolism
• Pulmonary fibrosis
• Shock
• Sleep apnea
Causes of Hypoxemia
Hypoxemia is usually triggered off by respiratory disorders. Additionally, hypoxemia may also
be caused as a result of one or a combination of the following:
1. Hypoventilation: This refers to a condition when the oxygen (PaO2) content is the blood
decreases and a marked increase in the levels of carbon dioxide is observed. This lowered
PaO2 content can cause hypoxemia.
2. Low Inspired Oxygen: The FiO2 content in the blood is called as the fraction of inspired
oxygen in the blood. A decrease in this fraction of inspired oxygen may cause
hypoxemia.
3. Left to right shunt: This is another cause of hypoxemia. A left-to-right shunt is a
condition when there is a transfer of blood from the left side of the heart to its right side.
This may occur as a result of a hole in the following walls: the arterial walls, the wall
separating the two upper chambers (left and right atrium) or the wall separating the two
lower chambers (left and right ventricles) of the heart.
4. Ventilation-Perfusion mismatch: This is a condition in which an imbalance between the
volume of gas expired by the alveoli (alveolar ventilation) and the pulmonary capillary
blood flow is seen. This mismatch may cause hypoxemia.
5. Diffusion Impairment: In this condition, a marked reduction is seen in the oxygen
movement from the alveoli to capillaries. This restricted movement may trigger
hypoxemia.
Symptoms of Hypoxemia
The symptoms of hypoxemia depend on the severity i.e. the amount by which the partial pressure
has reduced.
1. Prone Positioning
The prone position refers to lying flat on the ground, with your face downwards. The prone
position is known to increase oxygenation. It can be used as a treatment for mild hypoxemia. The
effectiveness of prone positioning as a treatment of acute respiratory disorders is still under
suspect.
2. Mechanical Ventilation
Mechanical ventilation is a mechanism by which it is possible to aid or substitute spontaneous
breathing mechanically. Continuous Positive Airway Pressure (CPAP) is a device that provides
mechanical ventilation. It is an effective way of treating severe hypoxemia. This is a device that
forces a steady stream of air into the nasal passage. This flow, which is set at a pressure that can
overcome obstructions, prevents the airway from closing. The pressure to be maintained, should
be determined through careful observation.