UNIVERSITY OF CEBU - BANILAD

Gov. M. Cuenco Ave, Cebu City, 6000 Philippines

College of Nursing
Telephone No: (032) 231- 8631

NCM 106 – Pharmacology

Course Outputs /Assessment of Learning for CILO # 1

Written Outputs (Mental Models, Group Activity and Reflection Journal)

Name of Student : Sanchez, Kaye Cyril T.

_________________________ Yr.& Sec. : 2-D
_______________
Module/Topic : Module 6 – Cardiovascular Drugs
_________________________ Date : 11-22-21
_______________

1. Create a Drug Study on Cardiovascular Drugs that are commonly used in clinical settings. Utilize the drug study template.

a. Medical-Surgical Ward ( 3 Medications )

b. Intensive Care Unit ( 2 Medications )

c. Out-patient Department ( 1 Medication)

Pharmacology Module 1st Semester S.Y. 2021- 2022 UCBC Page 1

 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631
Medical-Surgical Ward

DRUG STUDY
Patient : Palacio, Ma. Reshel
_________________________________ Age : _______________________
55 Hospital No. : __________
20556468
Impression : Patient has hypertension
_________________________________ Attending : Dr. Aike Ubay
_______________________ Room No. 001
: __________
Allergic to : No known allergies
_________________________________ Physician

GENERIC/BRAND DOSE, STRENGTH,

INDICATION/ MECHANISM ADVERSE EFFECT AND
AND AND NURSING RESPONSIBILITIES CLIENT TEACHING
OF ACTION CONTRAINDICATIONS
CLASSIFICATION FORMULATION

Generic: Ordered: Indication: Adverse Effect:

- Assess for any allergy to doxazosin, Instruct patient to:
Doxazosin To manage hypertension Dizziness, somnolence,
headache, edema, prazosin, or terazosin.
and to treat the symptoms - Do not drive or engage in
fatigue/malaise, - Monitor BP with patient lying down and
Brand: of benign prostatic other potentially
nausea, vomiting, and standing; doses above 4 mg increase the
hypertrophy, which may hazardous activities for
Cardura Timing: risk of postural hypotension.
include urinary frequency, asthenia 12–24 h after the first
Contraindications: - Be alert for signs of depression, dose.
Classification: urgency, and nocturia,
nervousness, or other changes in mood - Use caution when rising
among other symptoms. Clients allergic to
Antihypertensive Mechanism of action: and behavior. Notify physician if these from a sitting or supine
Duration: prazosin or terazosin
changes become problematic. position in order to avoid
Alpha-blockers Blocks the alpha-1 and patients with
- Assess peripheral edema using girth orthostatic hypotension
adrenergic receptors history of orthostatic
Other forms: and syncope -
resulting in a decrease hypotension. measurements, volume displacement,
Tablets - Report to the physician
systemic vascular resistance and measurement of pitting edema. episodes of dizziness or
and a corresponding Report increased swelling in feet and palpitations. These will
decrease in BP. ankles or a sudden increase in body require a dosage
weight due to fluid retention. adjustment.

Pharmacology Module 1st Semester S.Y. 2021- 2022 UCBC Page 2

 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

DRUG STUDY
Patient : Labiste, Gem Angiely
_________________________________ Age : 27
_______________________ Hospital No. 20556468
: __________
Impression : Patient has hypertension
_________________________________ Attending : Dr. Aike Ubay
_______________________ Room No. 002
: __________
Allergic to : No known allergies
_________________________________ Physician
GENERIC/BRAND DOSE, STRENGTH,
INDICATION/ MECHANISM ADVERSE EFFECT AND
AND AND NURSING RESPONSIBILITIES CLIENT TEACHING
OF ACTION CONTRAINDICATIONS
CLASSIFICATION FORMULATION

Generic: Ordered: Indication: Adverse Effect:

- Identify reason for therapy, onset, type Instruct patient to:
Clonidine To treat mild to moderate Dry mouth,
of symptoms, and previous treatment.
hydrochloride hypertension and spasticity. drowsiness, dizziness, - Avoid potentially
- Monitor BP closely
sedation, and hazardous activities
Brand:
constipation. - Monitor I&O during period of dosage until reaction to drug
Catapres has been determined
Timing: adjustment. Report change in I&O ratio
Contraindications: due to possible sedative
Classification: or change in voiding pattern. effects.
Clients with - Assess compliance with drug regimen in - Do not omit doses or
Antihypertensive Duration: Mechanism of action: hypersensitivity to stop the drug without
a supportive manner with pill counts, or
Central acting Stimulates alpha-adrenergic clonidine. Disorders of consulting the physician.
receptors of the CNS, cardiac pacemaker other methods. - Do not take OTC
Other forms: resulting in the inhibition of activity and conduction. medications, alcohol, or
- Supervise closely patients with history
Patch, oral tablet, the sympathetic vasomotor other CNS depressants
of mental depression, as they may be
and oral extended center and decrease nerve Pregnancy and without prior discussion
release tablet impulse. lactation. subject to further depressive episodes. with physician.
- Do not breast feed
while taking this drug.

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

DRUG STUDY
Patient : Sanchez, Kristine Chloe
_________________________________ Age : 31
_______________________ Hospital No. 20556468
: __________
Impression : Patient has hypertension
_________________________________ Attending : Dr. Aike Ubay
_______________________ Room No. 003
: __________
Allergic to : No known allergies
_________________________________ Physician
GENERIC/BRAND DOSE, STRENGTH,
INDICATION/ MECHANISM ADVERSE EFFECT AND
AND AND NURSING RESPONSIBILITIES CLIENT TEACHING
OF ACTION CONTRAINDICATIONS
CLASSIFICATION FORMULATION

Generic: Ordered: Indication: Adverse Effect: - Note reasons for therapy, other agents Instruct patient to:
Prazosin Mild to moderate Dizziness, drowsiness, trialed, outcome.
hydrochloride hypertension alone or in headache, lack of - Assess cardiopulmonary status and - Take first dose at
combination with other energy, weakness, renal function. bedtime.
Brand:
palpitations, nausea - Monitor patient's blood pressure and
antihypertensive drugs. - Do not drive or operate
Minipress Timing: pulse rate.
- Elderly patients may be more sensitive machinery for 24 hrs. after
Contraindications:
Classification: to the drug's hypotensive effects. the first dose.
Antihypertensive Clients with - Monitor patient compliance. - food may delay
Duration: Mechanism of action: hypersensitivity to - If first does is more than 1 mg, first- absorption and minimize
Alpha-1- Produces selective prazosin or related dose syncope may occur. side effects of the drugs.
adrenergic blockade of postsynaptic quinazolines. - Full therapeutic effect of drug is
Other forms: - avoid rapid changes in
blocking drug alpha-1-adrenergic reached within 4-6 weeks.
Capsules body positions that may
receptors. Dilates arterioles - Educate the patient about weight loss,
and veins, thereby exercise programs as needed. precipitate weakness
decreasing total; peripheral - Provide resources for complementary dizziness, and syncope.
resistance and decreasing and alternative therapies to promote - Do not stop medication
DBP more than SBP. positive coping mechanisms and stress unless directed.
reduction

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631
Intensive Care Unit

Patient : Bernales, Rosemarie

_________________________________ Age 38
: _______________________ Hospital No. 20556468
: __________
Impression : Patient has hypertension.
_________________________________ Attending : Dr. Aike Ubay
_______________________ Room No. 004
: __________
Allergic to : No known allergies
_________________________________ Physician

GENERIC/BRAND DOSE, STRENGTH,

INDICATION/ MECHANISM ADVERSE EFFECT AND
AND AND NURSING RESPONSIBILITIES CLIENT TEACHING
OF ACTION CONTRAINDICATIONS
CLASSIFICATION FORMULATION

Generic: Ordered: Indication: Adverse Effect:

- Note reasons for therapy, type, onset, Instruct patient to:
Esmolol Supraventricular tachycardia Dizziness, sweating,
pain/redness at characteristic of S&S.
in those with atrial - Counsel patients about
fibrillation or atrial flutter in injection site, - Document CP assessments, ECG, and
Brand: VS. additional interventions to
postoperative or other headache, confusion,
fatigue, rash, itchy skin - Assess for hypertension and help control cardiac
Brevibloc Timing: emergent situations when
short term control is and hypotension bradycardia. arrhythmias, including
Classification: needed. Tachycardia and regular exercise, caffeine
Contraindications: - Administer in a monitored
Beta-adregenic hypertension during surgery restriction, stress
environment.
blocking agent Duration: or postoperatively. Hypersensitivity to reduction, moderation of
Mechanism of action: esmolol, severe sinus - Do not dilute concentrate with sodium
bicarbonate. alcohol consumption, and
Preferentially inhibits beta-1 bradycardia, heart block
Other forms: receptors. Has no greater than first - Not for direct IV push administration. smoking cessation.
IV infusion, membrane-stabilizing or degree, sick sinus - To minimize irritation and - Instruct patient or
injection intrinsic sympathomimetic syndrome, thrombophlebitis do not infuse family/caregivers to
activity. Decreases HR and decompensated heart
concentrations greater than 10 mg/ml. report other troublesome
AV nodal conduction velocity failure, and Cardiogenic
and increases AV refractory shock. side effects.
period

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

DRUG STUDY
Patient : Dacillo, Marlo
_________________________________ Age 37
: _______________________ Hospital No. 20556468
: __________
Impression : Patient has hypertension
_________________________________ Attending : Dr. Aike Ubay
_______________________ Room No. 005
: __________
Allergic to : No known allergies
_________________________________ Physician
GENERIC/BRAND DOSE, STRENGTH,
INDICATION/ MECHANISM ADVERSE EFFECT AND
AND AND NURSING RESPONSIBILITIES CLIENT TEACHING
OF ACTION CONTRAINDICATIONS
CLASSIFICATION FORMULATION

Generic: Ordered: Indication: Adverse Effect: - Note reasons for therapy, other agents -
Instruct patient to:
To treat chronic stable Flushing, increased
Nicardipine prescribed, outcome.
angina alone or in angina, hypotension, - Establish baseline data before - Take at the same time
hydrochloride
Brand: combination with beta- palpations, treatment is started including BP, pulse, each day.
adrenergic blocking agent. tachycardia, and lab values of liver and kidney - Report any
Cardene Timing: function.
And hypertension alone or vasodilation, anxiety, persistent/bothersome
and dizziness. - Assess for CHF, if beta blockers
Classification: combination with other side effects.
Contraindications: prescribed, monitor closely
Calcium antihypertensive drugs. - Maintain proper intake
- Monitor ECG, renal and LFTs, note any
Mechanism of action: Used in advance aortic
Channel blocker Duration: dysfunction. of fluids to avoid
Moderately increases Co stenosis due to the - Closely monitor blood pressure and constipation.
and HR and significantly effect on reducing heart rate since it may produce
Other forms: - Avoid alcohol and limit
decreases peripheral afterload, and lactation. symptomatic hypotension and
Capsules caffeine.
vascular resistance. tachycardia.
(extended release) - Avoid prolong sun
- Observe for large peak and trough
Capsules differences in BP. Initially, measure BP at exposure.
(immediate peak effect (1–2 h after dosing) and at - Report any change in
release) trough effect (8 h after dosing). psychologic state.

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631
Out-patient Department
DRUG STUDY
Patient : Ano-os, Louise
_________________________________ Age : _______________________
45 Hospital No. 20556468
: __________
Impression : Patient has hypertension
_________________________________ Attending : Dr. Aike Ubay
_______________________ Room No. 006
: __________
Allergic to : No known allergies
_________________________________ Physician
GENERIC/BRAND DOSE, STRENGTH,
INDICATION/ MECHANISM ADVERSE EFFECT AND
AND AND NURSING RESPONSIBILITIES CLIENT TEACHING
OF ACTION CONTRAINDICATIONS
CLASSIFICATION FORMULATION

Generic: Ordered: Indication: Adverse Effect:

- Note diseases onset, reasons for Instruct patient to:
Olmesartan To treat high blood pressure Dizziness, diarrhea, GI
therapy, risk factors, other medical
medoxomil alone or in combination with upset, insomnia, and - May take with or without
headache. problems, other agents trailed, outcome.
Brand: other hypertensive drugs. food and with other
- List prescribed drugs to ensure none
prescribed BP
Benicar Timing: interaction. medications.
Contraindications: - Monitor BP, hydration status, CBC, - Change position slowly
Classification: electrolytes, renal, LFT’s; reduce dose and avoid dehydration to
Hypersensitivity to the
Antihypertensive Mechanism of action: with dysfunction. prevent sudden drop in BP
Duration: drug or any component
- Dosage adjustment is not and dizziness.
agent- Selectively blocks the of the product.
2-6 hours - Practice reliable
angiotensin II binding of angiotensin II to Lactation. recommended for the elderly or those
Other forms: contraception since drug
receptor the AT, receptor in vascular with moderate to severe renal or hepatic may cause fetal death.
Tablets smooth muscle, resulting in dysfunction.
antagonist - Continue low-fat, low-
a decrease in BP. - May be given with or without food. sodium diet, regular
exercise, smoking and
alcohol cessation to gain
BP control.

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

2. Briefly organize and bring together main ideas. Explain in your own words. (50 – 150 words for each question)
I. TM, a 57-year-old man, has thrombophlebitis in the right lower leg. IV heparin, 5000 units by bolus, was given. Following the IV bolus, heparin
5000 units given subcutaneously every 6 hours was prescribed. Other therapeutic means to decrease pain and alleviate swelling and redness
were also prescribed, and an aPTT test was ordered.
A. Was TM’s heparin order within the safe daily dosage range?
Answer:
TM’s heparin order is within the safe daily dosage range. The standard bolus dosage of IV heparin is 5,000 units, and the patient
received the same. While the standard dosage of IV heparin is given by an infusion of 20,000-40,000 units in 24 hours. Which means
that every 6 hours, the patient can take a minimum of 5,000-10,000 units. In in this situation, TM is given a dosage of 5,000 units every
6 hours which is under the normal dosage range. Therefore, it is clear that the daily dosage of TM was in the safe daily dosage range.
B. What are the various methods for administering heparin?
Answer:
Heparin is administered subcutaneously, wherein it is injected into the layer of the skin just below the epidermis and the dermis, in
areas such as the upper arm, thighs, two inches around the navel, hip bone, and the buttocks. Moreover, it can also be given
intravenously, wherein the medication is infused into the body of the patient through the veins, it could be in the form of intermittent
or continuous infusion.
C. Why was an aPTT test ordered? How would you determine whether TM is within the desired range? Explain your answer.
Answer:
An aPTT is a test used for detecting deficiencies for clotting factors and it was ordered to monitor the patient's response
to heparin therapy. Heparin is a blood thinner and if consumed in large quantities that are not required for the body, it can decrease the
count of the platelet and lead to prolonged aPTT result. However, if the patient is taking the desired dose of heparin, his aPTT result
would be in the desire range which is 1.25 to 2.5 times in the control level.
After 5 days of heparin therapy, TM was prescribed oral warfarin 5 mg daily. An INR test was ordered.
D. What is the pharmacologic action of warfarin? Is the warfarin dose within the safe daily dosage range? Explain your answer.
Answer:
Warfarin is an anticoagulant, it disrupts the coagulation cascade to reduce frequency and extent of thrombus formation. By interfering
with the synthesis of vitamin K-dependent clotting factor resulting in depletion of clotting factor II, VII, IX, and X. The normal dosage
of warfarin for an adult is 5-10 milligrams per day and can be maintained from 2-10 milligrams per day. TM is given 5 milligrams per
Day which means that the daily dosage of warfarin given to the patient is within the safe daily dosage.

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

E. What is the half-life and protein binding for warfarin? If a patient takes a drug that is highly protein bound, would there be a
drug interaction? Explain your answer.
Answer:
The half-life of warfarin is generally 20 to 60 hours; however, it is highly variable among individuals. Meanwhile its protein binding
is 99%. Thus, there would be a drug interaction if the patient takes another medication that is highly protein bound. When a patient
takes in another medication that is highly protein bound this could result in the displacement of warfarin from the protein binding site,
which increases warfarin free plasma concentration, and increase the risk of warfarin toxicity.
F. Why was an INR ordered for TM? What is the desired range?
Answer:
International Normalized Ratio (INR) testing was ordered because it is as an integral part of warfarin treatment. INR is done to ensure
the desire dose of the warfarin, it has a critical role in maintaining the warfarin response within a therapeutic range, to provide the
benefits of anticoagulation, while avoiding the risks of hemorrhage. The therapeutic INR ranges between 2.0 to 3.0. INR levels.
G. What serious adverse reactions could result with prolonged use or large doses of warfarin?
Answer:
Prolonged or taking large doses of warfarin could result in the following adverse reactions: red spots on the skin that look like a rash,
severe headache or dizziness, heavy bleeding after an injury, heavy bleeding during monthly period in women, severe stomach pain or
vomiting blood, pink, red, or dark brown urine, and black or bloody bowel movements
H. What patient teaching interventions should the nurse include? List three interventions.
Answer:
In the nurse’s patient teaching intervention, she should teach the patient that the intake of aspirin along with warfarin causes heavy
bleeding, thus the patient should seek physician advise first before doing so. Moreover, the nurse should advise the patient to take
laboratory test such as PT (prothrombin time) or INR (international normalized ratio) to ensure that the medication is in the therapeutic
dose. And lastly, the patient must avoid activities that may cause injury or cuts and bruises since he/she is taking a blood thinner that
may slow down blood clotting which could result to excessive bleeding.
I. Months later, TM has hematemesis. What nursing action should be taken?
Answer:
The nursing action to be taken in the given case is to provide drugs or food rich in vitamin k. This will decrease the outflow of blood
from the body and increase the clotting of blood.

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

3. JH had a myocardial infarction (MI) 3 years ago. He was prescribed gemfibrozil 600 mg twice daily before meals, but his cholesterol remained between
220 and 240 mg/dL, and his LDL was 140 mg/dL. His anticholesterol drug was changed to simvastatin 20 mg/day in the evening.
A. How does simvastatin differ from gemfibrozil?
Answer:
Gemfibrozil and simvastatin are used to treat high cholesterol and triglyceride levels but have different mechanisms. They belong in
different drug classes, gemfibrozil is a lipid-regulating agent while simvastatin is an HMG-CoA reductase inhibitor. Moreover, gemfibrozil
has high side effects and does not lower the risk of heart attacks whereas simvastatin has the most minimal side effects and can decrease
the risk of heart attacks which makes it the preferred choice of drug.
B. Why do you think JH’s cholesterol drug, gemfibrozil, was changed to simvastatin?
Answer:
JH had a history of myocardial infraction and is at high risk of getting it again due to very high cholesterol level. Gemfibrozil can prevent
the formation of abnormal lipid level by increasing the HDL and simultaneously lowering the LDL. However, the expected changes did
not occur and the patient had an LDL of 140mg which is considered to be borderline in a patient who already has heart problems. Thus, the
drug was changed to simvastatin which has a greater benefit than gemfibrozil in decreasing heart attacks and strokes.
C. While JH is taking simvastatin, which group of serum levels should be monitored?
Answer:
While taking simvastatin, JH should monitor his lipid levels which includes his total cholesterol, HDL, LDL, and triglycerides to assess the
changes, LFT (liver function test) since the drugs has effects on the liver, CBC since there will be a rise in patients taking the medication,
and CPK to rule out muscle wasting.
D. How long after taking simvastatin should JH’s cholesterol and lipoproteins be checked?
Answer:
After starting a statin such as simvastatin, it takes about six weeks for cholesterol levels to stabilize, so most doctors would re-check the
cholesterol and lipoproteins after about eight weeks. There is a need for a blood test when taking medications such as simvastatin to check
whether the blood cholesterol level has come down and lipoproteins are on normal range.

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

E. What is the maximum dose for simvastatin?

Answer:
The maximum daily dosage of simvastatin according to the FDA is 40 mg per day which was originally 80 mg per day. The 80-mg dosage
has been found to significantly increase the risks of myopathy and rhabdomyolysis, thus the change of the maximum dosage. The 80 mg/day
should be used only for individuals who have been taking simvastatin 80 mg chronically without evidence of myopathy or rhabdomyolysis.
F. JH complains of muscle pain and muscle weakness. What might this indicate?
Answer:
Muscle pain and muscle weakness is due to the elevated plasma levels of simvastatin acid and is dose related. It may indicate that the
patient my have been given higher simvastatin dosage. As mentioned above taking high doses of simvastatin significantly increases the
risks of myopathy and rhabdomyolysis which are conditions manifested by muscle weakness and pain. It is best for the patient to consult
his physician and should not discontinue drug unless directed.
G. Could JH receive both gemfibrozil and simvastatin? Explain your answer.
Answer:
Using gemfibrozil together with simvastatin is not recommended. Combining these medications can increase the risk of side effects such
as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue, and possibly
death. However, doctors may prescribe it in instances where the benefit of further alteration in lipid level is likely to outweigh the risk of
the drug combination but careful monitory should be done. But in JH case, it is best to take the simvastatin alone since combining both
drugs may do more harm than good.
H. JH is on vacation and does not have enough simvastatin tablets. What should he do?
Answer:
In instances like this where the patient does not have enough simvastatin tablets, it is recommended for the patient to go to pharmacy with
the prescription to try and procure the medicine. But in cases where there none, the patient may have a strict diet control and take the
medication as soon as possible. The patient may also try other alternatives, but should ask his physicians advise first before taking any.

Pharmacology Module 1st Semester S.Y. 2021- 2022 UCBC Page 11

 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

References:

Clonidine Drug Study And Nursing Implication | RNspeak. (2021, May 29). RNspeak | Nursing Journal. Retrieved November 21, 2021, from

https://rnspeak.com/catapres-clonidine-drug-study/

Doxazosin | Davis’s Drug Guide for Rehabilitation Professionals | F.A. Davis PT Collection | McGraw Hill Medical. (n.d.). F.A Davis P.T.

Collection. Retrieved November 21, 2021, from https://fadavispt.mhmedical.com/content.aspx?bookid=1873§ionid=139009146

nursing considerations. (n.d.). Prazosin (Minipress). Retrieved November 21, 2021, from https://prazosin-hypertension.weebly.com/nursing-

considerations.html

NICARDIPINE HYDROCHLORIDE. (n.d.). Rob Holland. Retrieved November 21, 2021, from

http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/N029.html

Heparin Dosage. (2019, December 3). Drugs.Com. Retrieved November 22, 2021, from https://www.drugs.com/dosage/heparin.html

Heparin (Heparin): Uses, Dosage, Side Effects, Interactions, Warning. (2020, October 27). RxList. Retrieved November 22, 2021, from

https://www.rxlist.com/heparin-drug.htm

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

Activated partial thromboplastin time. (n.d.). Lab Tests Online AU. Retrieved November 22, 2021, from

https://www.labtestsonline.org.au/learning/test-index/aptt

Mullokandov, E. (2015, August 5). Protein Binding Drug-Drug Interaction between Warfarin and Tizoxanide in Human Plasma. Austin

Publishing Group. Retrieved November 22, 2021, from https://austinpublishinggroup.com/pharmacology-therapeutics/fulltext/ajpt-v2-

id1038.php

Shikdar, S. (2021, May 10). NCBI - WWW Error Blocked Diagnostic. NCBI. Retrieved November 22, 2021, from

https://www.ncbi.nlm.nih.gov/books/NBK507707/

Statins: Common questions answered - Heart Matters magazine. (n.d.). Heart Matters. Retrieved November 22, 2021, from

https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/drug-cabinet/statins

Drug Interactions between gemfibrozil and simvastatin. (n.d.). Drugs.Com. Retrieved November 22, 2021, from https://www.drugs.com/drug-

interactions/gemfibrozil-with-simvastatin-1165-0-2067-0.html

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 UNIVERSITY OF CEBU - BANILAD
Gov. M. Cuenco Ave, Cebu City, 6000 Philippines
College of Nursing
Telephone No: (032) 231- 8631

Prepared by:

_______________________
Students Signature over
Printed Name

Submitted to:

Lemuel C. Candelasa, EdD(c) ,MAN,RN

ProfeAmeliaor – Pharmacology

Pharmacology Module 1st Semester S.Y. 2021- 2022 UCBC Page 14