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An Introduction To Survival Analysis Using Stata

The document summarizes updates made to a book on survival analysis using Stata. The updates reflect new features in Stata 11, including revised syntax for categorical variables and new syntax for predictions after Cox regression. A new chapter was also added on competing risks analysis.

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Rachkara Paul
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68 views

An Introduction To Survival Analysis Using Stata

The document summarizes updates made to a book on survival analysis using Stata. The updates reflect new features in Stata 11, including revised syntax for categorical variables and new syntax for predictions after Cox regression. A new chapter was also added on competing risks analysis.

Uploaded by

Rachkara Paul
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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An Introduction To Survival Analysis Using Stata

Book · January 2010


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Mario A Cleves
University of South Florida
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Preface to the Third Edition
This third edition updates the second edition to reflect the additions to the software
made in Stata 11, which was released in July 2009. The updates include syntax and
output changes. The two most notable differences here are Stata’s new treatment of
factor (categorical) variables and Stata’s new syntax for obtaining predictions and other
diagnostics after stcox.
As of Stata 11, the xi: prefix for specifying categorical variables and interactions
has been deprecated. Whereas in previous versions of Stata, you might have typed

. xi: stcox i.drug*i.race

to obtain main effects on drug and race and their interaction, in Stata 11 you type

. stcox i.drug##i.race

Furthermore, when you used xi:, Stata created indicator variables in your data that
identified the levels of your categorical variables and interactions. As of Stata 11, the
calculations are performed intrinsically without generating any additional variables in
your data.
Previous to Stata 11, if you wanted residuals or other diagnostic measures for Cox
regression, you had to specify them when you fit your model. For example, to obtain
Schoenfeld residuals you might have typed

. stcox age protect, schoenfeld(sch*)

to generate variables sch1 and sch2 containing the Schoenfeld residuals for age and
protect, respectively. This has been changed in Stata 11 to be more consistent with
Stata’s other estimation commands. The new syntax is

. stcox age protect


. predict sch*, schoenfeld

Chapter 4 has been updated to describe the subtle difference between right-censoring
and right-truncation, while previous editions had treated these concepts as synonymous.
Chapter 9 includes an added section on Cox regression that handles missing data
with multiple imputation. Stata 11’s new mi suite of commands for imputing missing
data and fitting Cox regression on multiply imputed data are described. mi is discussed
in the context of stcox, but what is covered there applies to streg and stcrreg (which
also is new to Stata 11), as well.
xx Preface to the Third Edition

Chapter 11 includes added discussion of three new diagnostic measures after Cox
regression. These measures are supported in Stata 11: DFBETA measures of influence,
LMAX values, and likelihood displacement values. In previous editions, DFBETAs were
discussed, but they required manual calculation.
Chapter 17 is new and describes methods for dealing with competing risks, where
competing failure events impede one’s ability to observe the failure event of interest.
Discussion focuses around the estimation of cause-specific hazards and of cumulative
incidence functions. The new stcrreg command for fitting competing-risks regression
models is introduced.

College Station, Texas Mario A. Cleves


July 2010 William W. Gould
Roberto G. Gutierrez
Yulia V. Marchenko

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