ADVIA® Chemistry Interface

Operating Instructions

040D0060-02, Rev. A, 2009-09

©2009 Siemens Healthcare Diagnostics Inc. All rights reserved.
No part of this manual or the products it describes may be reproduced by any means or in
any form without prior consent in writing from Siemens Healthcare Diagnostics.
ADVIA, ADVIA CentraLink, ADVIA WorkCell, and LabCell are trademarks of
Siemens Healthcare Diagnostics.

The information in this manual was correct at the time of printing. However, Siemens
continues to improve products and reserves the right to change specifications, equipment,
and maintenance procedures at any time without notice.
If the ADVIA LabCell or ADVIA WorkCell CDX system is used in a manner different
than specified by Siemens, the protection provided by the equipment may be impaired.
Observe all warning and hazard statements.
ADVIA Chemistry Interface Operating Instructions 3

Contents

1 Overview ...........................................................................5
Enhanced LAS Software Features .................................................. 5
Hardware Overview .......................................................................... 6
Software Overview ........................................................................... 8
Automation System Software .................................................................. 8
LineMaster Software ............................................................................... 9
Router Software .....................................................................................15
ADVIA Chemistry System Software........................................................15
Operating Sequence ..............................................................................16

2 Operating the System ....................................................18

Turning the Interface On................................................................ 18
Turning the Interface On (Enhanced LAS Software) ................... 20
Running Sample Tubes from the Instrument Sample Tray......... 23
Turning the Interface Off................................................................ 24

3 Maintenance ...................................................................25
Daily Maintenance .......................................................................... 25

4 Troubleshooting .............................................................26
Processing Events ......................................................................... 26
Using the Diagnostics Screens..................................................... 27
Using the Diagnostics Screen.................................................................27
Using the Diagnostics Screen (Enhanced LAS Software).......................30
Resolving Interface Fatal Error Conditions.................................. 33
Resolving an Interface Fatal Error Condition ..........................................33
Resolving an Interface Fatal Error Condition (Enhanced LAS Software) 35
Recovering from Pause States...................................................... 36
Recovering from the Pause State...........................................................37
Recovering from the Pause State (Enhanced LAS Software) .................38

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Unlocking and Flushing the Gate During Processing................. 39

Troubleshooting Skipped Sample Tube Conditions ................... 41
Troubleshooting a Skipped Sample Tube Condition ...............................41
Replenishing Reagents During Processing
(Enhanced LAS Software).............................................................. 42

5 Sample Management......................................................43

6 System Configuration ....................................................44

Enhanced Routing (Enhanced LAS Software) ........................................44

Appendix A: Safety Information ........................................45

Appendix B: Warranty and Support Information..............46

Contact Information ....................................................................... 46

Appendix C: Supplies.........................................................47

Appendix D: Specifications ...............................................47

Appendix E: Symbols.........................................................47

Appendix F: Glossary.........................................................48

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1 Overview
The ADVIA Chemistry system is a clinical chemistry analyzer for in vitro diagnostic
use that runs tests on human serum, plasma, or urine in random access, batch, and STAT
(interrupt) modes. The ADVIA 1650, ADVIA 1800, and ADVIA 2400 Chemistry
systems are collectively called the ADVIA Chemistry system. The ADVIA Chemistry
Interface Kit allows you to include the ADVIA Chemistry system on your
ADVIA® LabCell® or ADVIA WorkCell™ CDX system.
This document is a supplement to the ADVIA Automation Solutions Operator’s Guide.
For operating procedures of the ADVIA Chemistry system, refer to the appropriate
ADVIA Chemistry Operator’s Guide.
IMPORTANT: This document provides separate information and instructions for
Enhanced LAS software only where features and procedures significantly differ. Sections
specifically for Enhanced LAS software are clearly labeled; if no designation appears,
information and procedures apply to the ADVIA Chemistry systems with and without
Enhanced LAS software.

Enhanced LAS Software Features

This document includes information about Enhanced LAS software, an upgrade for the
the ADVIA 1800 Chemistry system and the ADVIA 2400 Chemistry system. The
ADVIA 1650 Chemistry system cannot run Enhanced LAS software. Enhanced LAS
software provides the following features:
• The ADVIA Chemistry system transmits reagent status and event messages to the
LineMaster. These messages provide important information about instrument,
reagent, and sample status.
• When the instrument detects a sample integrity problem, such as a clot or short
sample, the system sends a message to the LineMaster and routes the sample to SIQ
for inspection.
• If there is no workorder, a sample is out of sequence, or the barcode is not read, the
system does not aspirate the sample tube before it moves from the interface gate to
the main track.
• If a reagent is not available, a test is not calibrated, or a test fails QC, the enhanced
routing feature allows a sample tube to route to another instrument that can perform
the test. If no other instrument with that test is available, the sample tube routes to the
Partial Processed tray. This feature improves Turn Around Time.
• If an ancillary reagent is not available, the instrument pauses. Sample tubes can route
to another instrument or to the Partial Processed tray. When the ancillary reagent is
replenished, the instrument returns to normal operation.
• Tests can be disabled due to missing reagents, Cal errors, ISE cal errors, optional QC
out, and ISE urine cal error. This information is communicated to the LineMaster.

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Hardware Overview
The ADVIA Chemistry interface contains the following components:

1 Monitor
2 Workstation
3 Automation interface computer
4 ADVIA Chemistry system computer
5 On/Off switch
6 Top cover

Figure 1. ADVIA Chemistry Interface (front)

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1 Main breaker
2 Auxiliary power
3 Interface box (not used with Enhanced LAS software)
4 Waste container with waste pump
5 Water input
6 Power junction box

Figure 2. ADVIA Chemistry Interface (back)

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Software Overview

Automation System Software

The automation system uses 2 software applications:
• The LineMaster workspace serves as the primary point of interaction between the
operator and the automation system. The LineMaster computer communicates with
and controls the active status of all instruments and components. The LineMaster
workspace reports analytical instrument events, tube status, and automation system
status.
• The Router software controls the divert gates and interface gates. It defines the route
of a sample tube on the track and balances the workload among instruments that
perform the same tests.
The operator uses the LineMaster software to perform the following operations for the
ADVIA Chemistry interface:
• select the ADVIA Chemistry interface
• change the state of the ADVIA Chemistry interface
• view events
• view and change the Test List screen
• view the Diagnostics screen

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LineMaster Software
The LineMaster workspace provides access to the Details, Events, Test List, and
Diagnostics screens. To access ADVIA Chemistry system screens, select the
ADVIA Chemistry station button.

Figure 3. LineMaster Workspace

For systems with more than 1 ADVIA Chemistry system, each ADVIA Chemistry
system station button provides access to information, events, and data unique to that
interface.
NOTE: If you use ADVIA Chemistry systems with Enhanced LAS software and
ADVIA Chemistry systems without Enhanced LAS software, ensure that station names
allow you to easily identify these different systems.
IMPORTANT: For Enhanced LAS software, all ADVIA Chemistry system LineMaster
screens display the Diagnostics button above the Test List button.

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Details Screen
The Details screen displays when you select the ADVIA Chemistry system station
button. The Details screen shows the current operational state of the interface.

Figure 4. ADVIA Chemistry Details Screen

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Events Screen
The Events screen displays event messages associated with the ADVIA Chemistry
system interface.When an event occurs, a white, yellow, or red status bar appears above
the ADVIA Chemistry system station button. A white bar indicates a minor event; a
yellow bar indicates that the interface requires operator attention; a red bar indicates a
failure that causes the interface to stop. You can review the event log to identify these
conditions.

Figure 5. ADVIA Chemistry Events Screen

The Events screen displays only the event messages associated with the
ADVIA Chemistry interface. The screen includes the following buttons:
• The Event Details button displays details about the selected event.
• The Acknowledge button removes the selected event from the unacknowledged list.
• The Acknowledge All button removes all events from the unacknowledged list.
You can view the Acknowledged list by selecting the blank field above
Unacknowledged. This displays additional minor events that are auto-acknowledged.
You can use the arrow in the Log Time column to change the sort order. The arrow in the
Severity column allows you to choose a specific severity level. In addition, you can sort
by the Log Time, Machine, Severity, Message, and Code columns by placing the cursor
above the column name and typing a keyword or number.

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Test List Screen

The Test List screen displays tests that are active on the ADVIA Chemistry interface.
Refer to the ADVIA Automation Solutions Operator’s Guide for general information on
the Test List screen.

Figure 6. ADVIA Chemistry Test List Screen

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Figure 7. ADVIA Chemistry Test List Screen (Enhanced LAS Software)

The Test List screen for Enhanced LAS software includes the following additional
information:
• A new Instrument column shows availability of tests. A test can be unavailable when
calibration is necessary, and when the test is not within control range, or when
reagents are empty. If the checkbox is cleared, the test cannot run.
• If a common reagent is empty, the Online button turns light blue, indicating that the
instrument is in the Pause state. The instrument completes tests for sample tubes that
are currently in process if they do not require common reagents. Refer to Recovering
from the Pause State (Enhanced LAS Software) for additional information.
• For routing purposes only, you can select a forced routing test. Forced routing tests
send a sample tube that requires a rerun to a different instrument or to the same
instrument, ignoring normal routing requirements. For repeat/reflex tests, a forced
routing test downloads with a workorder from the ADVIA CentraLink® system to the
LineMaster. Forced routing tests do not appear in the test map and have no results.
NOTE: You must first configure a forced routing test on the global test list. When
you select the down arrow above the Selected column, you can see the selected
checkbox, a cleared checkbox, and a blank area. When you select the blank area, the
system displays the complete global test list. You can then select a forced routing test
from the list.

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Diagnostics Screen
The Diagnostics screen displays status information about the ADVIA Chemistry
interface. You can use this screen for troubleshooting purposes and on a daily basis when
you bring the ADVIA Chemistry interface offline.
To access diagnostic features, select the ADVIA Chemistry system station button and
then select Diagnostics.

Figure 8. ADVIA Chemistry Diagnostics Screen

Figure 9. ADVIA Chemistry Diagnostics Screen (Enhanced LAS Software)

For descriptions of all Diagnostics screen fields, refer to Using the Diagnostics Screens.

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Router Software
For information on the Router software, refer to the ADVIA Automation Solutions
Operator’s Guide.

ADVIA Chemistry System Software

For operating procedures of the ADVIA Chemistry system, refer to the
ADVIA Chemistry Operator’s Guide.

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Operating Sequence
The ADVIA Chemistry interface operates according to the following sequence:
1. A sample tube routes to the ADVIA Chemistry station.
2. At the divert gate, the system reads the sample tube barcode and diverts the sample
tube to the side track.
3. The system sends a workorder request to the ADVIA CentraLink system.
4. At the interface gate, the sample tube moves to the pick position.
5. The system reads the barcode again and verifies that the sequence of tubes in the side
track is correct.

1 Gate control button

2 Divert gate
3 Side track
4 Interface gate
5 Pick position
6 Place position
7 Main track

Figure 10. ADVIA Chemistry Station

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6. The system aspirates directly from the sample tube.

NOTE: If there is no workorder, the sample is out of sequence, or the barcode is not
read, the system aspirates the sample without producing results and moves the sample
tube to the main track. For Enhanced LAS software, when these conditions occur, the
system does not aspirate the sample tube before it moves from the interface gate to
the main track. If this occurs, refer to Troubleshooting for instructions.
7. When processing completes, the sample tube moves back to the side track and then to
the main track.

CAUTION
Do not remove samples directly from the side track or interface gate. If you remove a
sample directly from the side track or interface gate, the system aspirates the next sample
tube without producing results and routes it to the main track. For Enhanced LAS
software, the system does not aspirate the sample tube before it moves from the interface
gate to the main track.
8. The ADVIA Chemistry system sends the test results directly to the
ADVIA CentraLink system.

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2 Operating the System

Turning the Interface On

Perform the following steps to turn the interface on:
1. At the ADVIA Chemistry system, lift the gate control button.
The interface gate homes and the gate control button illuminates.
2. At the ADVIA Chemistry system workspace, select Initialize.
Wait for initialization to complete.
NOTE: Ensure that the system is in Ready or Start mode before you complete this
procedure.
3. At the LineMaster workspace, select the ADVIA Chemistry system station button.

Figure 11. ADVIA Chemistry Details Screen

4. At the Details screen, select Offline.
Wait for the Offline button to turn white.
5. Select Diagnostics.
6. At the Diagnostics screen, ensure that the /HNREADY checkbox is selected.
If the checkbox is not selected, refer to Troubleshooting.
7. Select Online.

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8. At the ADVIA Chemistry system workspace, perform the following steps:

a. Select Start.
b. At the Start Conditions screen, in the Ordinary sample area, below the Outside
analyze field, select the Routine smp. Analyze checkbox.

Figure 12. ADVIA Chemistry System Start Conditions Screen

c. Select Start.
d. Select OK.
9. At the Diagnostics screen, perform the following steps:
a. Ensure that the /BMONL checkbox is selected and wait 2 minutes.
b. Ensure that the /BMREADY checkbox is selected.
If either checkbox is cleared, refer to Troubleshooting.
10. Wait while the cuvette washes complete and the Online button transitions from light
blue to white.
11. Wait for the station button to turn green.

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Turning the Interface On (Enhanced LAS Software)

Perform the following steps to turn the interface on:
1. At the ADVIA Chemistry system, lift the gate control button.
The interface gate homes and the gate control button illuminates.
2. At the ADVIA Chemistry system workspace, select Initialize.
Wait for initialization to complete.
NOTE: Ensure that the system is in Ready or Start mode before you complete this
procedure.
3. At the LineMaster workspace, select the ADVIA Chemistry system station button.

Figure 13. ADVIA Chemistry Details Screen

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4. At the Details screen, select Diagnostics.

Figure 14. ADVIA Chemistry Diagnostics Screen

5. At the Diagnostics screen, select Offline.
Wait for the Offline button to turn white.
6. At the Test List screen, verify that the Instrument column checkbox is selected for all
required tests (refer to Figure 7).
7. If the checkbox is not selected, perform the following steps:
a. Select Shutdown.
b. Replenish reagents.
c. Repeat steps 4-7.
d. Select Online.

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8. At the ADVIA Chemistry system workspace, perform the following steps:

a. Select Start.
b. At the Start Conditions screen, in the Ordinary sample area, below the Outside
analyze field, select the Routine smp. Analyze checkbox.

Figure 15. ADVIA Chemistry System Start Conditions Screen

c. Select Start.
d. Select OK.
9. At the LineMaster, bring the system online.
The Online button remains light blue.
10. Wait while the cuvette washes complete.
11. Wait for the Online button to turn white.
12. Wait for the station button to turn green.

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Running Sample Tubes from the Instrument Sample Tray

Perform the following steps to run sample tubes from the sample tray at the front of the
ADVIA Chemistry system for pediatric, STAT, or short samples:
1. At the ADVIA Chemistry system workspace, select Sample Pause.
Wait until the Start button becomes available.
2. Select Start.

Figure 16. ADVIA Chemistry System Start Conditions Screen

3. At the Start Conditions screen, perform the following steps:
a. Load sample tubes in the Sample Manager.
b. In the Ordinary sample area, below the Tray no.field, select the Routine smp.
Analyze checkbox.
c. Next to Analyze mode, ensure that the Barcode radio button is selected.
d. Select Start.
e. Select OK.
f. At the Sample confirmation screen, select OK.
After the system aspirates all samples on the ADVIA Chemistry system sample
tray, processing resumes from the automation system.

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Turning the Interface Off

As part of your end–of–day routine, perform the following procedure to turn the interface
off.
1. At the ADVIA Chemistry system workspace, ensure that the system is in the
WATCH or READY state.
This indicates that all samples are processed. If necessary, wait until the system
processes all samples before proceeding.
2. At the LineMaster, bring the system offline.
3. Select Shutdown.
4. If the Shutdown button does not turn white, at the Diagnostics screen, select
Terminate.
This forces the interface to the shutdown state.
5. Ensure that no samples are in the side track.
If samples are present, press the gate control button down and then lift it up to flush
the samples from the gate and side track. Manage these sample tubes according to
your laboratory standard practices. Refer to Unlocking and Flushing the Gate During
Processing for additional information.

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3 Maintenance
For ADVIA Chemistry system maintenance information, refer to the ADVIA Chemistry
Operator’s Guide.

CAUTION
Do not allow any liquid to flow into the interface gate during cleaning. Wring or dry the
soft cloth or cotton-tipped applicator so that it is damp before you begin cleaning.

Daily Maintenance
Inspecting the ADVIA Chemistry Interface Gate
Perform the following steps at the interface gate:
1. Inspect the gate for the presence of dust or serum:
a. Inspect the barcode reader.
b. Inspect the gate sensors.
c. Inspect the index wheel.
2. If you find dust or serum, use a mild soapy solution and a soft cloth or cotton-tipped
applicator to remove any soil.
3. Dry the area with a soft cloth.
4. At the ADVIA Chemistry system, ensure that all reagents and consumables are filled.

Inspecting the Divert Gate

Perform the following steps at the divert gate:
1. Inspect the divert gate, singulate, and stop fingers for the presence of dust or serum:
2. If you find dust or serum, use a mild soapy solution and a soft cloth or cotton-tipped
applicator to remove any soil.
3. Inspect the barcode reader.
4. If necessary, clean the lens with a lens cloth.
5. At the ADVIA Chemistry system, ensure that all reagents and consumables are filled.

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4 Troubleshooting

Processing Events
The ADVIA Chemistry Events screen displays event messages associated with a specific
ADVIA Chemistry system station and provides recommended corrective actions.
Event messages are listed chronologically, with the most recent event at the top. You can
sort event messages by log time, severity, machine, message, and event code. You can
also arrange event messages by acknowledged events or unacknowledged events.
When an ADVIA Chemistry system event occurs, a white, yellow, or red alert bar
displays above the ADVIA Chemistry system station button.
Perform the following steps when an event occurs:
1. At the LineMaster workspace, select the ADVIA Chemistry station button.
2. Select Events.
3. Select an event.
4. Select Event Details.
5. Carefully read the event message and follow the recommended corrective actions.
6. Acknowledge the event by selecting the event and then selecting Acknowledge or
Acknowledge All.
The Event Log screen displays system fatal, station fatal, operator required, and warning
labels in the Status column. Event messages have no status notation.

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Using the Diagnostics Screens

The Diagnostics screen displays status information about the ADVIA Chemistry
interface. You can use this screen on a daily basis and for troubleshooting purposes. The
Diagnostics screen differs for Enhanced LAS software.

Using the Diagnostics Screen

Figure 17. Diagnostics Screen

Inputs from Instrument Area

The Inputs from Instrument area displays signals from the ADVIA Chemistry system.
A checkmark next to … Indicates …
/BMINIT the ADVIA Chemistry system is initializing.
/BMONL the ADVIA Chemistry system initiated a run or is
running. This signal is required to process samples.
/BMREADY the system is online and is ready to process sample
tubes. In normal operation, BMREADY displays a
checkmark approximately 2 minutes after BMONL
displays. This signal is required to process samples.
/IDREQ a request for a barcode. This is a momentary signal
that the operator cannot see.

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A checkmark next to … Indicates …

/BMSMP the ADVIA Chemistry system is sampling. In normal
operation, this checkmark displays when the Lock
Status checkbox is selected. When the BMSMP is
checked, the interface gate does not move.

CAUTION
Do not attempt to unlock a gate while the
BMSMP checkbox is selected. Unlocking the
gate while the BMSMP checkbox is selected
can damage the probe or spill a sample tube.
Before unlocking a gate, at the
ADVIA Chemistry system, check the status of
the probe. Refer to Unlocking and Flushing
the Gate During Processing for additional
information.
/BMTRBL a fault occurred at the ADVIA Chemistry system. The
ADVIA Chemistry system will not process sample
tubes until you resolve the problem.

Outputs to Instrument Area

The Outputs to Instrument area displays signals from the LAS interface computer. The
/HNREADY and /SMPREQ are used for maintenance and troubleshooting procedures.
A checkmark next to … Indicates …
/HNREADY the ADVIA Chemistry system is online or offline. When
this checkbox is cleared, the ADVIA Chemistry interface
cannot process sample tubes and does not start. If you
attempt to start the system when HNREADY is not
available, an HNREADY not available message displays at
the ADVIA Chemistry interface.
/SMPREQ a sample tube arrived at the aspiration position of the
ADVIA Chemistry system. This is a momentary signal.
The HNNEXT field is not used.

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Gate Information Area

At the Gate Information area, a Lock Status checkbox indicates that the
ADVIA Chemistry system is aspirating a sample tube and the gate is locked. If you press
and then lift the gate control button when the gate is locked, the system will not flush
tubes and pucks from the interface gate. Refer to Unlocking and Flushing the Gate
During Processing for additional information.
NOTE: You do not need to monitor this signal during normal operation. During
emergency maintenance and troubleshooting procedures, you can use the Unlock Gate
button to unlock and then flush the gate in a proper sequence. Currently, the Pick
Request, OK to Pick, and Picking checkboxes are not useful because they do not reflect
real-time activity.

Display Area
The Display area includes the I/O Signals, Serial Messages, and Controller Activity
checkboxes. Ensure that these checkboxes are selected.

Actions Area
The Actions area contains the following buttons.
Button Description
Clear Log Select this button to clear text in the Log area. Your
technical support provider uses this text area.
Terminate Select this button only when the interface is
unresponsive and requires emergency maintenance.
The Terminate button forces the interface to the
shutdown state.
Unlock Gate Select this button to clear the Lock Status
checkbox. Use this button only for emergency
maintenance and troubleshooting procedures.

Log Area
In the Log area, serial messages reflect the communication between the automation
system and the ADVIA Chemistry system.

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Using the Diagnostics Screen (Enhanced LAS Software)

Figure 18. ADVIA Chemistry Diagnostics Screen (Enhanced LAS Software)

Interface Actions Area

The Interface Actions area contains the following buttons.
Button Description
Display Queue Select this button to view all sample tube barcodes
currently in the side track.
Reset Queue Select this button to reset the automation system
queue. When you use this button, sample tubes are
flushed from the side track, circle the track once
and then divert to the instrument.
NOTE: If you select this button when the system is
online, the Change State window displays, forcing
you to bring the system offline.
Terminate Select this button only when the interface is
unresponsive and requires emergency maintenance.
The Terminate button forces the interface to the
shutdown state.

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Button Description
Unlock Gate Select this button to unlock the interface gate. Use
this button only for emergency maintenance and
troubleshooting procedures. Refer to Unlocking
and Flushing the Gate During Processing for
additional information.
System Status Select this button to test communication between
the instrument and LineMaster.
If you select this button when the system is in the
shutdown state, the Change State window displays,
forcing you to bring the system offline.
NOTE: Use this button only when the system is in
the online or offline state.

Gate Information Area

The Gate Information area includes the following checkboxes.
Within … A checkmark next to … Indicates …
Interface Puck at Pick a puck is at the pick position of the interface
Gate area gate.
Tube at Pick a sample tube is at the pick position of the
interface gate
Lock Status the instrument is aspirating a sample tube
and the gate is locked. If you press and then
lift the gate control button when the gate is
locked, the system will not flush tubes and
pucks from the interface gate.
You do not need to monitor this signal
during normal operation. During emergency
maintenance and troubleshooting procedures,
you can use the Unlock Gate button to
unlock and then flush the gate in a proper
sequence. Refer to Unlocking and Flushing
the Gate During Processing for additional
information.
Router area Pick Request the instrument is ready to receive and
aspirate sample tubes.
Ok to Pick the automation system transmitted the
barcode to the instrument.
Picking the instrument is aspirating a sample.

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Barcode Area
You can use the fields in the Barcode area to monitor the quality of the barcodes and the
barcode reader in real time. The Barcode Actions area contains the following fields:
Field Description
Last Diverted This field displays the barcode of the last sample
tube diverted to the instrument. *
Gate Barcode This field displays the barcode of the sample tube
currently being aspirated.*
Last Departed This field displays the barcode of the last sample
tube moved to the Place position of the interface
gate.*
*
These fields display No Read when the system cannot read the barcode.

Message Log Area

The Message Log area can display the following information.
• The Message Log Filter drop-down menu allows you to change the level of message
filtering passed to the interface when interface transitions from shutdown to offline,
or from shutdown to offline to online.
You can select 1 of the following levels:
• None so that no messages display.
• Low to display events.
• Medium to display the test map when the interface goes from shutdown to
offline, as well as events, reagent information, and easily-readable messages that
are not in code. Medium is the default selection.
• The Save XML File button immediately saves the XML log file for troubleshooting
purposes. It closes the current log and opens a new log file.
• The Clear log button clears the message log.

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Resolving Interface Fatal Error Conditions

The ADVIA Chemistry interface automatically transitions to the shutdown state when a
fatal error condition occurs or if the interface is unresponsive. A red bar displays over the
station button. If this occurs, perform the appropriate recovery procedure. Recovery
procedures differ for Enhanced LAS software.

Resolving an Interface Fatal Error Condition

• Perform the following steps to resolve a fatal error condition:

1. At the ADVIA Chemistry system workspace, select to view the error report.

Figure 19. ADVIA Chemistry System Operation Panel

2. At the Error Report screen, double-select the Stop or Warning + Stop errors to view
details.
Follow instructions for resolving the error if instructions display.
3. Resolve the problem that caused error.
4. Select Initialize.
The system performs wash and homing functions.
5. At the LineMaster workspace, bring the interface offline:
The station button turns white.
6. If the station button does not turn white, perform the following steps:
a. Select Diagnostics.
b. At the Diagnostics screen, select Terminate.
If the ADVIA Chemistry system does not go to the white shutdown state, contact
your technical service provider.
7. Select Online.

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8. At the ADVIA Chemistry system workspace, perform the following steps (refer to
Figure 12):
a. Select Start.
b. At the Start Conditions screen, in the Ordinary sample area, below the Outside
analyze field, select the Routine smp. Analyze checkbox.
c. Select Start.
d. Select OK.
The system starts its wash cycles, which complete in approximately 2 minutes.
9. At the LineMaster, verify that the ADVIA Chemistry interface is ready to process
sample tubes:
a. At the LineMaster workspace, select the ADVIA Chemistry system station
button.
b. Select Diagnostics.
c. At the Diagnostics screen, in the Inputs from Instrument area, ensure that
/BMONL is selected.
d. Ensure that the /BMREADY checkbox is selected.
10. Acknowledge the events:
a. At the ADVIA Chemistry Details screen, select Events.
b. Select Acknowledge All.
NOTE: If signals are missing or if additional events occur, check the cable
connections on the interface box (refer to Figure 2) and the corresponding cable
connections at the back of ADVIA Chemistry interface computer. If the problem
persists, contact your technical support provider.

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ADVIA Chemistry Interface Operating Instructions 35

Resolving an Interface Fatal Error Condition

(Enhanced LAS Software)
Perform the following steps to resolve a fatal error condition:
1. At the LineMaster, select the ADVIA Chemistry system station button.
2. At the Details screen, select Events.
3. At the the Events screen, find the event that caused the fatal error.

4. At the ADVIA Chemistry system, select to view the error report.

5. At the Error Report screen, double-select the Stop or Warning+Stop error.
6. At the Error Report Details screen, confirm the error and follow the directions that
display.
7. Resolve the problem that caused the error.
8. Select Initialize.
Wait until the ADVIA Chemistry system initializes and enters the Ready state.
9. At the LineMaster, bring the system offline.
The station button turns white.
10. If the station button does not turn white, perform the following steps:
a. Select Diagnostics.
b. At the Diagnostics screen, select Terminate.
This forces the ADVIA Chemistry system to the white shutdown state. If this
does not occur, contact your technical service provider.
11. Select Online.
12. At the ADVIA Chemistry system workspace, perform the following steps (refer to
Figure 15):
a. Select Start.
b. At the Start Conditions screen, in the Ordinary sample area, below the Outside
analyze field, select the Routine smp. Analyze checkbox.
c. Select Start.
d. Select OK.
The system starts its wash cycles, which take approximately 2 minutes to
complete. The Online button remains light blue until the wash cycles complete.
When the Online button turns white, the ADVIA Chemistry interface is ready to
process sample tubes.
NOTE: If the test map does not display or if additional events occur, check the
network cable connections at the ADVIA Chemistry system interface switch. In
addition, check cable connections at the back of the ADVIA Chemistry interface
computer and those at the ADVIA Chemistry system. After checking all cables,
restart the ADVIA Chemistry system. If the problem persists, contact your technical
support provider.

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ADVIA Chemistry Interface Operating Instructions 36

Recovering from Pause States

The ADVIA Chemistry system can enter the Pause state when it cannot process sample
tubes. In the Pause state, the automation system stops diverting sample tubes to the
instrument. When the interface is online and the ADVIA Chemistry system is in the
Pause state, the Online station button turns a green-blue color.
The ADVIA Chemistry system can enter the pause state under any of the following
conditions:
• Low levels of oil reserves, system diluent, ISE buffer, wash solution DI water, and
saline solution exist.
• The ADVIA Chemistry system processes sample tubes from the sample tray. When
processing from the sample tray completes, the ADVIA Chemistry system leaves the
pause state automatically and resumes processing from the automation system.
• The ADVIA Chemistry system loses the /BMREADY signal or the BMONL signal
(the checkbox is cleared on the Diagnostics screen). These fields appear only for
ADVIA Chemistry systems without Enhanced LAS software.

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ADVIA Chemistry Interface Operating Instructions 37

Recovering from the Pause State

Perform the following procedure to recover from the Pause state:
1. At the ADVIA Chemistry system, perform the following steps:
a. Verify that the ADVIA Chemistry system is not processing sample tubes from
the sample tray.
b. Verify that the Error Report screen does not display Stop or Warning +Stop
errors.
If Stop or Warning + Stop errors exist, resolve the errors.
2. Check the cable connections on the interface box (refer to Figure 2) and the
corresponding cable connections at the back of ADVIA Chemistry system.
If necessary, remove and reconnect the cable.
3. At the LineMaster workspace, select the ADVIA Chemistry system station button.
4. Select Diagnostics.
5. Verify that the /BMREADY signal or the BMONL signal are selected.
6. At the ADVIA Chemistry system workspace, perform the following steps (refer to
Figure 12):
a. Select Start.
b. At the Start Conditions screen, in the Ordinary sample area, below the Outside
analyze field, select the Routine smp. Analyze checkbox.
c. Select Start.
d. Select OK.
The system starts its wash cycles, which take approximately 2 minutes to
complete.
7. At the LineMaster, bring the system offline.
The station button turns white.
8. If the station button does not turn white, perform the following steps:
a. Select Diagnostics.
b. At the Diagnostics screen, select Terminate.
If the ADVIA Chemistry system does not go offline, contact your technical
service provider.
c. Select Offline.
9. Select Online.
10. When the Online button turns white, verify that the ADVIA Chemistry interface is
ready to process sample tubes.

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ADVIA Chemistry Interface Operating Instructions 38

Recovering from the Pause State (Enhanced LAS Software)

Perform the following procedure to recover from the Pause state for Enhanced LAS
software:
1. At the LineMaster workspace, select the ADVIA Chemistry system station button.
2. At the Details screen, select Events.
3. Select an event appropriate for the instrument that is paused.
4. At the Events screen, select Event Details.
5. At the ADVIA Chemistry system, perform the following steps:
a. Verify that the ADVIA Chemistry system is not processing sample tubes from
the sample tray.
b. Verify that the Error Report screen does not display Stop or Warning +Stop
errors.
If Stop or Warning + Stop errors exist, resolve the errors.
6. Replenish any common reagent that is depleted.
7. At the LineMaster workspace, select the ADVIA Chemistry system station button
and verify that the system resumed processing.
8. If the ADVIA Chemistry system is not processing samples, select Initialize.
9. At the ADVIA Chemistry system workspace, perform the following steps (refer to
Figure 15):
a. Select Start.
b. At the Start Conditions screen, in the Ordinary sample area, below the Outside
analyze field, select the Routine smp. Analyze checkbox.
c. Select Start.
d. Select OK.
The system starts its wash cycles, which take approximately 2 minutes to
complete.
10. At the LineMaster, bring the system offline.
11. Select Online.
12. Verify that the station button turns white and that the ADVIA Chemistry system
begins processing samples.
If the ADVIA Chemistry system does not resume processing, contact your local
service provider.

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ADVIA Chemistry Interface Operating Instructions 39

Unlocking and Flushing the Gate During Processing

CAUTION
Do not flush the gates while the system processes sample tubes unless emergency
maintenance or troubleshooting conditions occur. Flushing the gates can damage the
system. Always replenish reagents and consumables prior to starting daily operation.
If necessary, perform the following steps to flush the gate while the system processes
sample tubes:
1. At the ADVIA Chemistry system workspace, select Pause.
Wait while the system aspirates 1 or 2 more sample tubes in the Pause/shift state, in
transition to the pause state.
2. At the LineMaster workspace, select the ADVIA Chemistry station button.
3. At the Details screen, select Offline.
4. Select Diagnostics.
5. At the Diagnostics screen, select Unlock Gate.
6. If the gate remains locked, perform the following steps:
a. Switch to the Router computer.
b. At the Router Main screen select F1 MAIN.
c. Select the stack light of the ADVIA Chemistry system station.
d. At the Station screen, verify that the Picking flag is gray.

Figure 20. Router Station Screen

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ADVIA Chemistry Interface Operating Instructions 40

e. If the picking flag is yellow, at LineMaster, select Offline.

f. Select Online.
g. Wait several seconds and then select Offline.
h. Select Shutdown.
This clears the picking flag.
7. At the ADVIA Chemistry system, press the gate control button down and then lift
it up.
Sample tubes move from the ADVIA Chemistry system interface gate and return to
the main track.
NOTE: Allow the system to finish processing the aspirated sample tubes. When
processing completes and the system is in the Ready state, replace reagents or
consumables according to normal procedures.
8. Perform the necessary emergency maintenance or troubleshooting procedures.

CAUTION
At the ADVIA Chemistry system, ensure that you select the Initialize button. If you do
not select the Initialize button, the system skips tubes at the interface gate. Skipping these
tubes can damage the sample probe.
9. At the ADVIA Chemistry system, select the Initialize button to clear the internal
sample queue.
10. At the LineMaster workspace, select the ADVIA Chemistry system station button.
11. At the Details screen, select Offline.
12. At the ADVIA Chemistry system workspace, perform the following steps (refer to
Figure 12):
a. Select Start.
b. At the Start Conditions screen, in the Ordinary sample area, below the Outside
analyze field, select the Routine smp. Analyze checkbox.
• At the LineMaster Diagnostics screen, wait until the BMREADY checkbox
displays a check.
• For Enhanced LAS software, verify that the Diagnostics screen displays the
test map.
c. Select Start.
d. Select OK.
The system starts its wash cycles, which take approximately 2 minutes to
complete.
13. Bring the interface online.

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ADVIA Chemistry Interface Operating Instructions 41

Troubleshooting Skipped Sample Tube Conditions

Troubleshooting a Skipped Sample Tube Condition

When barcode misread or a No Workorder condition occurs, the ADVIA Chemistry
system indexes, or skips, sample tubes. In order to maintain the internal queue, the
system aspirates the sample tube with the misread barcode. Subsequent sample tubes are
not impacted by barcode misreads.

CAUTION
Do not leave sample tubes on the automation system if they have repeatedly skipped.
Skipped sample tubes return to the ADVIA Chemistry system when the system reads
barcode at the divert gate but misreads it at the interface gate. For ADVIA Chemistry
systems without Enhanced LAS software, this causes depletion of the sample. For
Enhanced LAS software, the sample tube continues to circle the track but is not depleted.
Remove sample tubes that have repeatedly skipped from the automation system.
If the ADVIA Chemistry system alarm alerts you to a skipped sample tube, perform the
following procedure.
1. At the ADVIA Chemistry workspace, locate the SID of the skipped sample tube:

a. At the ADVIA Chemistry system, select to view the error report.

b. Double-select the message that reads LAS/RH: skip sample ID received.
c. Record the Pre-read ID, which is the SID of the skipped sample tube.
2. At the LineMaster workspace, select System > SIQ or press F5.
3. At the SIQ screen, select the Workorders tab.
4. In the SID field, enter the barcode number of the misread sample tube.
5. Select Enter.
6. When the sample tube information displays, select Route to SIQ.
If the sample tube is still on the track, it circles the track again and then routes to the
SIQ gate or SIQ tray.
7. Examine the sample tube barcode label for proper positioning and clarity.
8. If the necessary, replace the label according to your laboratory procedures.
9. Reintroduce the sample tube to the automation system via an SIQ gate or Load tray.

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ADVIA Chemistry Interface Operating Instructions 42

Replenishing Reagents During Processing

(Enhanced LAS Software)
If an individual reagent is low or empty, you can replenish reagents while the system
processes samples in several minutes. The ADVIA Chemistry system suspends sampling,
adds reagent to the last samples, and then allows you to add reagents.
Perform the following procedure to replenish reagents while the system is processing
samples:
1. At the ADVIA Chemistry system workspace, select RGT pause.

CAUTION
Do not select SCAN until you replenish reagents. Selecting SCAN before you replenish
reagents can damager reagent probes. Always replenish reagents before you select
SCAN.
The system aspirates several additional samples before it suspends processing and the
reagent trays stop moving. The RGT SCAN screen displays “After Loading
Reagents, click SCAN to perform a barcode scan.”
2. Replenish reagents.
3. Replace reagent covers.
4. At the RGT SCAN screen, select SCAN.
Wait until “BCD SCANNING …Please wait for a while” no longer displays and the
system resumes processing.
NOTE: The reagent or method may require an RBL or calibration before the method
becomes available.

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ADVIA Chemistry Interface Operating Instructions 43

5 Sample Management
For sample management information, refer to the ADVIA Automation Solutions
Operator’s Guide.

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ADVIA Chemistry Interface Operating Instructions 44

6 System Configuration

Enhanced Routing (Enhanced LAS Software)

The enhanced routing feature is available only with Enhanced LAS software and requires
a specific configuration. Discuss enhanced routing options with your local service
provider before you install Enhanced LAS software
NOTE: With enhanced routing, the system can create duplicate test aspirations, using
additional reagents and producing duplicate results. If you use enhanced routing, you may
need to change ADVIA CentraLink settings to avoid duplicate results.
If a reagent is not available, a test is not calibrated, or a test fails QC, enhanced routing
allows a sample tube to route to another instrument that can perform the test. If no other
instrument with that test is available, the sample tube routes to the Partial Processed tray.
Enhanced routing can offer faster Turn Around Time for sample tube processing.
If you turn off enhanced routing and a test is not available at an instrument, the system
marks all tests Route Complete, although some tests were not performed. In this case,
these sample tubes route to the Unload tray rather than to the Partial Processed tray. This
is the current behavior for systems without Enhanced LAS Software.

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ADVIA Chemistry Interface Operating Instructions 45

Appendix A: Safety Information

For all safety information related to the automation system, refer to the
ADVIA Automation Solutions Operator’s Guide.

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ADVIA Chemistry Interface Operating Instructions 46

Appendix B: Warranty and Support Information

For all warranty and support information related to the automation system, refer to the
ADVIA Automation Solutions Operator’s Guide.

Contact Information
This section provides the following information:
• the address of the Siemens authorized representative, which is the Siemens contact
within the European community
• the Siemens addresses for obtaining service and technical information and for
ordering supplies

Siemens Authorized Representative

Siemens Healthcare Diagnostics Ltd.
Sir William Siemens Sq.
Frimley, Camberley, UK GU16 8QD

Addresses
For technical assistance, contact your local technical support provider.
www.siemens.com/diagnostics

Siemens Healthcare
Diagnostics Pty Ltd
885 Mountain Highway
Bayswater Victoria 3153
Australia

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ADVIA Chemistry Interface Operating Instructions 47

Appendix C: Supplies
For all warranty and support information related to the automation system, refer to the
ADVIA Automation Solutions Operator’s Guide.

Appendix D: Specifications

Specification Requirements
Dimensions 1711 mm (W) x 867 mm (D) x 1340 mm (L)
Weight 630 kg (uncrated)
Interface Type Direct Interface
Power Requirements 13.6 amps @ 220 volts 50/60Hz
Air Supply NA
DI Water 40 liters per hour

Appendix E: Symbols
For information on automation system symbols, refer to the ADVIA Automation Solutions
Operator’s Guide.

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ADVIA Chemistry Interface Operating Instructions 48

Appendix F: Glossary
For a complete glossary of terms associated with automation systems, refer to the
ADVIA Automation Solutions Operator’s Guide.

A
ADVIA Automation A system of modular components that can be configured to
Solutions create custom, open laboratory automation systems for
sample tube management.
ADVIA Automation A term used by Siemens to describe its product line of
Solutions automated systems, including the ADVIA LabCell and
ADVIA WorkCell CDX systems. Each automation system is
comprised of modular components used to create laboratory
automation solutions for sample tube management.
Automation system An ADVIA LabCell or ADVIA WorkCell CDX system.
ADVIA CentraLink A data management software that manages the results and
QC for each instrument, and provides a connection to the
customer’s laboratory information system (LIS).
ADVIA CentraLink provides a single point of use for results
generated by the instruments connected to the automation
system.

B
Barcode A code consisting of lines of varying widths that can be read
optically with a scanning device.
Barcode reader An optical character reader that can read data represented by
bar codes and translate the codes into digital signals.

C
Cold storage A refrigerated area designated for storing completed
samples. Samples are assigned by the operator to predefined
cold storage locations within one or more refrigerators on a
particular door and shelf.

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ADVIA Chemistry Interface Operating Instructions 49

D
Divert gate A device on the main track of the conveyor that moves
sample tubes from the main track onto a side track. A
barcode reader scans the sample tube barcode label, and
based on information received from the ADVIA CentraLink
system, the sample is diverted onto the side track or
continues on to the next gate.

E
E-stop An emergency button or cord that immediately stops all
mechanical motion.
Event Log A LineMaster screen that displays and archives event
messages and recommended corrective actions.

F
G
Gate Divert gates and interface gates read barcodes and direct
sample tubes on the conveyor to instruments and modules,
where testing and processing take place.
Gate control button An on/off button located on top of the divert gate that turns
the station power, divert gate, and interface gate on and off.
Press the gate control button to turn the station off. Lift the
gate control button to turn the station on.
Global Test List A list of all laboratory tests that can be performed on or off
the automation system. The ADVIA CentraLink system, the
instrument test lists, and the sort tray use the global test list
to determine the routing of samples.

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ADVIA Chemistry Interface Operating Instructions 50

I
ID In the global test list, a unique numeric identifier assigned to
a sample for a specific test. The ID is a shortened form of
the test name that the laboratory uses to identify a test.
Instrument An analyzer, excluding the robot and other interface
components, that conducts medical tests or procedures on
samples.
Instrument Test List A subset of the global test list that defines which tests are
performed by a specific analyzer or module connected to the
automation system.
Interface gate A device on a side track, located directly in front of an
analyzer or module, that reads the sample barcode, then
selects and positions the sample so it can be processed by a
connected analyzer or module and returned to the main
track.
Interface computer A computer that builds an interface between the LineMaster
software and an instrument or module. An interface
computer controls signals and communication data to and
from the instrument.

J
K

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ADVIA Chemistry Interface Operating Instructions 51

L
Light tower Vertically stacked colored lights that indicate system status
information. The color of an illuminated light indicates the
operating status of a robot or gate.
• Red indicates a serious error occurred on the
automation system. The conveyor, robots, and
instruments and modules stop. The operator must
take corrective action.
• Yellow indicates a station is offline. The conveyor
continues to run. The operator must take corrective
action.
• White indicates all stations are online. The conveyor
continues to run. The operator should take corrective
action at the station.
• Green indicates the conveyor is running.

LineMaster A computer-based system that allows the operator to control

sample management for the entire automation system. Also
called the LineMaster workspace, it is the primary point of
interaction between the operator and the automation system.
The LineMaster server communicates with and controls the
active status of all instruments and components connected to
the system. The LineMaster reports events, tube status, and
automation system status.
LIS Lab Information System

M
Module A connected system, such as the Sample Manager, that
performs sample tube management functions but does not
analyze samples.

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ADVIA Chemistry Interface Operating Instructions 52

N
Name The name of a test in the global test list. This name must be
the same name used by the ADVIA CentraLink system.

O
Offline A station is not operational.
Non-robotic interfaces reach the offline state when the
station no longer diverts sample tubes to the side track.
Robotic interfaces reach the offline state after the instrument
or module checks all safety features and the robot homes.
Online A station is operational.
The automation system diverts samples to the station’s
interface gate, where they are picked by the robot and
processed or directly aspirated at the gate.
Overview screen The main screen of the LineMaster that displays the system
configuration.

P
Pick A robot action that picks up a sample tube from one point
prior to placing it at another point.
Pick position The position at an interface gate at which instrument probes
aspirate samples, or from which robots pick sample tubes for
processing.
Place position The position at an interface gate to which robots return
sample tubes after processing.
Puck A weighted cylindrical carrier that holds a single sample
tube as it moves on the main track and side tracks.

Q
Queue A line of sample tubes on the side track waiting for
processing. The queue typically holds up to 20 samples, with
15 extra positions reserved for STAT.

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ADVIA Chemistry Interface Operating Instructions 53

R
RCC Robot Control Cabinet. This component supports
instruments and modules containing robots. It houses all the
electronic robotic controls and a computer that
communicates with the LineMaster software.
Robot A mechanism that picks sample tubes or racks from one
position and places them at another on the automation
system. Robots are flexible and move in 3 axes: X, theta,
and Z. There are 2 types of robots:
• Interface robots pick sample tubes from the interface
gate and move them into the instrument or module.
• Internal robots move samples within an instrument or
module.
Router Software that routes samples to the appropriate stations by
controlling the divert gates and interface gates. The Router
software communicates with the ADVIA CentraLink system
and receives workorders with tests and ID information. The
Router software also determines, based on system
configuration inputs, the sequence of stations to which a
sample is delivered, and balances the workload between
stations with the same instruments or modules.

S
Sample A test tube filled with some media requiring testing or
processing. Samples may include serum, whole blood,
plasma, cerebrospinal fluid (CSF), urine, and QC materials.
All sample tubes must include a unique barcode label by
which the automation system can differentiate among
patients and among different sample types from the same
patient.
Sample Manager A module that moves sample tubes from the input trays to
the conveyor for processing, and when processing is
complete, from the conveyor to the output trays.
Sample tube A thin glass or plastic container, closed at one end,
containing a sample. The conveyor transports a sample tube
in a puck on the surface of the track. Sample tubes include a
unique barcode by which the automation system
differentiates among patients and among different sample
types from the same patient.

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ADVIA Chemistry Interface Operating Instructions 54

Shutdown A station is not in communication with the LineMaster

computer.
In the shutdown state, the robot or instrument stops placing
and picking samples. Independent of the automation system,
the instruments may continue operation. For instruments that
aspirate directly from the interface gate, the station waits for
an aspiration to complete before shutting down.
Sample ID The barcode number that identifies the sample to the
automation system. The barcode number links the sample
tube with the workorder.
SIQ Sample-in-question
SIQ station A station gate or a tray defined as SIQ in the Sample
Manager that receives sample tubes requiring manual
operator intervention.
The automation system sends samples to SIQ when it cannot
direct them to a station. This occurs when a sample barcode
is not readable, the sample has no workorder, the sample is a
duplicate, or sampling problems occurred at a station. After
the operator corrects the problem, the sample is checked into
the system.

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T
Test Analyzing a sample.
Tray A device that holds up to 100 sample tubes. Each tray has a
unique barcode on the top and all 4 sides for easy
identification in cold storage. The operator places trays into
the Sample Manager and defines each tray as 1 of the
following:
• Load Mixed tray, which contains sample tubes ready for
testing When the automation system includes a
Decapper, a Load Mixed tray accommodates sections of
capped and uncapped sample tubes.
• STAT tray, which contains sample tubes requiring
immediate processing. Sample tubes in STAT trays have
higher priority than sample tubes processed from any
other tray. When the automation system includes a
Decapper, the STAT tray accommodates sections of
capped and uncapped sample tubes.
• Unload tray, which contains sample tubes that were
processed and are ready for removal.
• Partial Processed tray, which contains sample tubes with
incomplete routes.
• SIQ tray, which contains sample tubes that are samples-
in-question (SIQ) or unknown samples and performs the
same function as an SIQ station.
• Centrifuge Override tray, which contains sample tubes
that do not route to the Centrifuge/Decapper interface
module. When the automation system includes a
Decapper, the Centrifuge Override tray accommodates
all capped or all uncapped sample tubes.
• MultiZone tray, which contains a maximum of 5
different zones, each of which can correspond to the
Unload tray, Partial Processed tray, and Sort tray types:
• Sort tray, which contains sample tubes sorted by tests.
• AutoSwitch tray, which the system can use for loading
and unloading sample tubes. When the automation
system includes a Decapper, the AutoSwitch tray
accommodates sections of capped and uncapped sample
tubes.
• Unknown tray, which contains sample tubes with
unknown status. The Sample Manager does not pick
sample tubes from an Unknown tray.

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ADVIA Chemistry Interface Operating Instructions 56

U
Username The name of the operator logged on to the automation
system.

W
Workspace The user interface of the automation system, also called the
LineMaster workspace, which includes a System
Management area and a Control Management area. The
System Management area displays system information
depending on the system button selected and contains the log
on badge. The Station Management area allows the operator
to select station buttons and view station-specific data.

X
Y
Z

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