Biology Module 7 Guide
Biology Module 7 Guide
education.nsw.gov.au
Table of contents
Year 12 Biology Module 7: Infectious disease..............................................................................................1
Table of contents.......................................................................................................................................... 2
The Year 11 course...................................................................................................................................... 3
Course overview.......................................................................................................................................... 4
Module summary.......................................................................................................................................... 5
Big ideas...................................................................................................................................................... 5
Relationships to other modules.................................................................................................................... 5
Core concepts.............................................................................................................................................. 6
Opportunities for extending concepts....................................................................................................... 6
Misconceptions and alternative conceptions............................................................................................ 7
Conceptual difficulties.............................................................................................................................. 8
Suggested teaching strategies..................................................................................................................... 9
IQ7-1: How are diseases transmitted?..................................................................................................... 9
IQ7-2: How does a plant or animal respond to a pathogen?....................................................................9
IQ7-3: How does the human immune system respond to a pathogen?.................................................10
IQ7-4: How can the spread of infectious diseases be controlled?..........................................................10
Resources.................................................................................................................................................. 12
IQ 7-1..................................................................................................................................................... 12
IQ 7-2..................................................................................................................................................... 13
IQ 7-3..................................................................................................................................................... 14
IQ 7-4..................................................................................................................................................... 14
Appendix one............................................................................................................................................. 15
IQ 7-2 Investigating plant pathogens..................................................................................................... 15
Appendix two.............................................................................................................................................. 15
IQ 7-2 Responses to pathogens............................................................................................................ 15
Appendix three........................................................................................................................................... 15
IQ7-4 Prevention, treatment and control................................................................................................ 15
Course overview
The Year 12 course follows some major themes that weave throughout all modules. These
include:
Survival: Individuals and populations have strategies that enable them to survive.
Some of these include successful reproduction, metabolism, responses to infection
and homeostatic mechanisms. The survival of species is reliant on genetic variation
in changing environments.
Patterns exist in biology: Various types of patterns can be observed in the natural
world. For example, the inheritance of certain traits and the occurrence of infectious
and non-infectious diseases can be predicted through the observation of patterns.
Although the biosphere is diverse, similarities and patterns in the molecular makeup
(e.g. DNA structure) of all species can be observed and these are explained through
evolution and common ancestry.
Technologies: Various types, including biotechnologies, can be used to better
understand biological processes. They can help us to better understand life in the
past, enhance survival and quality of life in human populations, productivity and
sustainability in the environment.
Society: Biology is influenced significantly by societal factors. The economy, cultural
influences and ethics have all played important roles in shaping how we understand
the living world.
Infectious diseases can significantly impact human health and that of other animals and
plants and can have devastating impacts on agricultural production. These impacts are not
equal throughout the world. Prevention of infectious diseases relies on limiting
transmission of pathogens and is dependent upon a range of biological, economic, social
and governance factors. The content focus is on:
Causes of infectious disease
Responses to pathogens
Immunity
Prevention, treatment and control of infectious disease
Big ideas
Survival: Infectious diseases are caused by pathogens. Pathogens or their products
must infect a host to cause disease. Preventing infectious disease depends on
preventing this transmission. Many animals and plants display a range of responses
to infection which are designed to isolate and destroy the pathogen and its products.
Patterns exist in Biology: Immunisation and mobility of individuals will affect the
spread of disease.
Technologies: Humans can treat and/or prevent some diseases with a range of
strategies, including medicines, which must be used appropriately to be effective.
The importance of prevention strategies in more recent years has been emphasised.
Society: infectious diseases have economic and social consequences and therefore
governments have a role in preventing infectious diseases.
Some potential future links to other Modules in the Year 12 course could include:
The concepts of epidemiology and the study of disease occurrence in populations
and data analysis is a theme that continues into Module 8.
Core concepts
The discovery that infection by an organism (pathogen) is the cause of disease was
essential to our understanding of disease treatment and prevention.
Recognising the mode of transmission is also essential in preventing the spread of
infectious disease.
Some animals and plants have innate responses to infection that distinguish
between self and not self. The innate responses are non-specific and are effective
against the majority of types of pathogens.
Animals also have an adaptive response to infection, called the immune response,
which is specific to each pathogen. The immune response usually destroys the
infection by the pathogen, but may take some time, during which the animal will
exhibit symptoms of the disease. As a result of a specific infection, the immune
response will also prevent the animal from getting a subsequent infection from the
same pathogen. This is called immunological memory.
Vaccination is a way of stimulating the immune system so that immunity to a specific
pathogen is achieved without infection. This is called acquired immunity.
Prevention is better than cure. Controlling the spread of disease is only achieved by
understanding how the disease is transmitted then limiting that transmission. There
are a wide range of methods available for preventing infectious disease and for
controlling the spread of infectious diseases.
Treatment may be provided to individuals if they become infected with a disease.
Pathogens are continually evolving resistance to drugs. In order for drugs (antivirals
and antibiotics) to remain effective they need to be prescribed and taken, according
to instructions.
Infectious diseases have an economic cost and social impacts for individuals and
society as a whole, because of their impact on both human health and agriculture.
Conceptual difficulties
Understanding the different types of pathogens may require explicit teaching and
repetition to avoid confusion, to be followed with formative assessment, such as exit
tickets and quizzes.
Understanding that the digestive tract, respiratory tract and urogenital tract are not
sterile and are separate from the sterile cranial, thoracic and abdominal cavities in
this sense.
Fever is one of the body’s responses to infection, designed to inhibit the growth of
pathogens and inactivate their products, rather than a product of the infection itself.
Use of the following terms correctly can sometimes be confusing and difficult – self
and not self, antibody and antigen.
The adaptive immune response, specifically, the cascades of responses and the
interaction between B & T cells can be quite challenging. Teachers may need to
encourage the use of flow charts and diagrams to outline some of the main steps
involved in adaptive immunity.
Distinguishing between the terms prevention, treatment and control can sometimes
be difficult possibly due to their misuse in the media.
Horizontal gene transfer in bacteria and viruses, and important in antibiotic and other
drug resistance, is a new concept that is contrary to all that students have learned
about the inheritance of genes.
Resources
World Health Organisation and Australian Institute of Health and Welfare both have
websites providing large amounts of high quality, reliable information that may be
used for planning lessons or secondary source research projects.
Local healthcare providers – May be able to provide information on current issues
facing the local community or talks on health safety and education. This can be a
powerful educational tool as it shows real world links and relevance of course
content.
Local Indigenous people (AECG) re application of Aboriginal protocols.
The Museum of Human Disease at UNSW offers educational tours for schools.
Garvan Institute has a range of videos and interactives.
Cosmos – an Australian based online magazine that summarises reports in scientific
journals and convert them to plain English so that they are accessible to high school
students.
Doherty Institute: based in Melbourne the Doherty Institute work on infection and
immunity through a broad spectrum of activities. This includes discovery research;
diagnosis, surveillance and investigation of infectious disease outbreaks; and the
development of ways to prevent, treat and eliminate infectious diseases
Science journal for kids: Cutting edge peer-reviewed science research adapted for
students.
IQ 7-2
Overview: Pests, diseases and disorders from Ausveg. This page provides a
diagnostic guide and key reference for pests, diseases and disorders affecting
vegetable crops in Australia. They hyperlinked topics provide further detailed
information about the pests, diseases, disorders – their identification, types,
management, and source of information and related tools.
Signalling between plants and pathogens: About plant diseases and disorders a
video about plant detection of pathogens, is a resource for extension of concepts.
Plant and Animal Defense (duration 13:04) in this video Paul Andersen describes
how plants and animals defend themselves against pathogens. He begins by
discussing the hypersensitive response in plants as a nonspecific form of immune
response. The later part of the video he discusses both the humoral and cell-
mediated immune response in mammals. This could be useful in IQ 7-3.
What is Snot? Video (duration 0:51) from the Science Learning Hub at the University
of Waikato. Dr Joanna Kirman talks about snot. Although it seems disgusting, we
learn snot is actually a good thing and is one of our weapons to fight disease. It is
produced to clear the airways of infectious diseases and anything else that should
not be there.
Making snot for the activity see Appendix one. From the web page you can
download the Word file for:
o introduction/background notes
o what you need
o what to do
o fake snot recipes.
Fever (duration 7:32) video from PBS Learning Media describes in detail the
response of overheating on a hot day and getting a fever and takes some of the
mystery out of fever. Some background reading and discussion questions are
included.
IQ 7-3
The Immune Response from McGraw Hill is a video animation that explains a
complex process (requires Internet Explorer and Flash player). Text and a short quiz
are included.
Infectious diseases - an interactive from ABPI, provides a broad overview of the
immune response for student formative assessment/revision.
IQ 7-4
How to wash your hands article from COSMOS. Researchers suggest that shorter
washing times for health workers can prevent bacterial spread in hospitals.
Age structure of Ebola outbreaks from BioInteractive. This activity guides the
analysis of published scientific figures from a study that investigated demographic
patterns in Ebola outbreaks from the Democratic Republic of the Congo. An
educator materials document includes a captioned figure, background information,
graph interpretation and discussion questions. The graph presented is a box and
whisker plot which the students may not have seen before, so this provides an
excellent opportunity to increase their knowledge of different data representations.
There are also links to other data studies including the Nipah virus outbreak in
Malaysia.
Discovery UK - The eradication of smallpox: invisible killers (duration 7:29) or TED
Ed Learning from smallpox: How to eradicate a disease (duration 5:45) are videos
that look at the strategies employed to eradicate smallpox.
Some possible resources for Measles:
o Video at SBS: Measles surge in Europe: What does it mean for Australia?
(duration 2:45) - looks at herd immunity and why it is so important.
o Measles in Australia (Australian Institute of Health and Welfare) – good graphs
and a concise report on the effectiveness of MMR vaccination.
o SBS world news video: No link between measles vaccine and autism, major
study confirms (duration 2:03). Looks at the underlying premise for anti-vaxxers
opposing the MMR vaccine, its validity and what the latest study shows about the
connection between MMR and autism.
Antibiotic resistance. Catalyst (ABC) looks at the problem of antibiotic resistance
and how researchers are approaching the problem.
Appendix two
IQ 7-2 Responses to pathogens
Watch video clip: What is snot? (duration 0:51) Discuss why snot is a good thing and why
there are different types/colours of snot. Divide students into small groups and give a
different type of snot (Science learning hub recipe) to each group. Discuss the texture of
each group’s fake snot - is it stringy or stretchy. Ask students again what snot is and what
it is for. Compare with students’ original answers.
Appendix three
IQ7-4 Prevention, treatment and control
An investigation of measles, or another disease that students could select from their
vaccination record.
Students investigate:
The disease the situation pre & post vaccination development, in Australia, another
first world country and a third world country.
What is limiting the uptake of vaccines in each?
Vaccination
Interpret data relating to the incidence and prevalence of infectious disease in populations,
for example:
mobility of individuals and the portion that are immune or immunised
and Working Scientifically outcomes Bio 11/12-3, 11/12-5, 11/12-6 and 12/12-7