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NEET Biology MCQ

The document contains a 50 question multiple choice quiz on molecular biology and genetics concepts like DNA structure, replication, transcription and translation. The questions cover topics such as DNA and RNA base pairing, genetic code, structure and function of genes, DNA as the genetic material, experiments supporting the DNA hypothesis, DNA replication, transcription and translation processes. An answer key with the correct response for each question is provided at the end.

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Ish Malik
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Download as PDF, TXT or read online on Scribd
275 views

NEET Biology MCQ

The document contains a 50 question multiple choice quiz on molecular biology and genetics concepts like DNA structure, replication, transcription and translation. The questions cover topics such as DNA and RNA base pairing, genetic code, structure and function of genes, DNA as the genetic material, experiments supporting the DNA hypothesis, DNA replication, transcription and translation processes. An answer key with the correct response for each question is provided at the end.

Uploaded by

Ish Malik
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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NEET Biology MCQ

Chapter-6 Molecular basis of Inheritance


1. A sample of DNA contains 20% of adenine. What is the quantity of guanine present?
A. 30 B. 20 C. 15 D. 25

2. Who proposed the concept of reverse transcription?


A. Crick &Temmin B. Temmin& Baltimore C. Watson & Chargaff
D. Chargaff

3. What is the name of process of addition of methyl guanosine triphosphate at the 5’


end of hn RNA?
A. Splicing B. Capping C. Tailing D. None of these

4. Find out the wrong pair/s?


1. rRNA- RNA polymerase I
2. tRNA- RNA polymerase II
3. mRNA-RNA polymerase III
A. Both 1 & 2 B. Both 2& 3 C. Only 1 D. Only 2

5. Who proposed base pairing rules of DNA?


A. James Watson B. Erwin Chargaff C. Francis Crick D. Frederic Griffith

6. Find out the incorrect pair


1. β- galactosidase – produces by z-gene
2. Permease – produces by y-gene
3. Transacetylase – produces by a-gene
A. 1 & 2 B. 2&3 C. All the statements D. None of the statements

7. What is the length of DNA having 75 base pairs?


A. 255A0 B. 112.5 A0 C. 750 A0 D. None of these

8. Which amino acids are present mostly in histone?


A. Arginine & Glycine B. Glycine & Lysine C. Arginine & Lysine D. Arginine &Valine

9. During tailing which molecule is added at the 3’ and of hnRNA?


A. Poly adenylate residue B. Methyl guanosine tri phosphate C. Methyl guanosine di
phosphate D. Adenosine monophosphate

10. Which type of histones interconnect two adjacent nucleosomes?


A. H1& H2A B. H2A & H2B C. H1 only D. H3 &H2A
11. Who discovered Lac operon?
A. Jacob & Monod B. Jacob & Watson C. Watson & Monod D. Crick & Monod

12. Which is the largest gene in Man?


A. Dystrophin B. Dystronin C. Dystromin D. Dystropin

13. What were the experimental materials used by Griffith to prove that DNA is the
genetic material?
A. E-coli & Streptococcus pneumonia B. Mice & Staphylococcus pneumonia C. Mice,
Streptococcus pneumonia & Staphylococcus pneumonia D. None of these

14. Which enzyme unwinds DNA double helix during DNA replication?
A. Topoisomerase B. Helicase C. SSB protein D. DNA polymerase

15. Who experimentally proved that DNA is the genetic material?


A. Meselson& Chase B. Hershey & Chase C. Hershey &Meselson D. Watson & Chase

16. Consider the following statements


1. Codes for amino acid methionine
2. Initiation codon
3. Stop codon
4. Sense codon

Which of the above statements are true with respect to AUG?

A. 1, 2 & 3 are correct B. 2, 3 & 4 are correct C. 1, 2 & 4 are correct D. Only 1 is
correct

17. Which codons are stop codons


A. UAA,UGC & UCG B. UAA,UGA& UAG

C. UAA,UGC & UGA D. UAA,UAG & UCG

18. Which amino acids are coded by the genetic codes GAG & GUG respectively
A. Glutamic acid & Glutamic acid B. Glutaric acid &Valine C. Glutaric acid &ProlineD.
Glutamic acid &Valine

19. The exchange of chromosomes segments between non-homologous chromosomes


is called

A. Translocation B. Deletion C. Transfer D. Frame shift


20. Okazaki fragments are
A. Short DNA fragments on the lagging strand
B. Short DNA fragments on the leading strand
C. The RNA primers required for initiation of DNA synthesis
D. The DNA fragment produced due to radiation action

21. RNA polymerizes which is on the promoter, moves to the structural genes to
transcribe them. However, it happens when
A. There is no repressor on the operator
B. There is repressor on the operator
C. Inducer binds to structural genes
D. RNA polymerase shifts first to regulator gene

22. The special unwinding enzyme that helps in breaking the weak hydrogen bond which
hold the two strands of DNA is
A. Primase B. DNA ligase C.DNA polymerase D. Helicase

23. Transfer of DNA from one bacteria to another through cell to cell contact is known as
A.Conjugation B.Transformation C.Transduction D.Transcription

24. The four nitrogen base sequence which form the code words for DNA
Language is
A. UTAC B. ACTU C. AGCU D. ATCG

25. DNA strands are antiparallel because of the presence of


A. H-bonds B. Peptide bonds C. Di sulphide bonds D.Phospho diester bonds

26. Transformation experiments using pneumococcus bacteria led to the hypothesis that
A. RNA is the transfer link between DNA and protein synthesis
B.Chromosomes are made up of DNA
C.DNA is genetic substance
D.Bacteria has sexual reproduction

27. The type of RNA specifically responsible for directing the proper sequence of amino
acids in protein synthesis is
A. Ribosomal RNA B.Messenger RNA C.Chromosomal RNA d) None

28. The base sequence of the strand of DNA is CATTAG CATGAT GAC. What will be the
sequence of RNA strand which is complimentary with the DNA?
A. GTA ATC GAT CTA B. UA AUC GUA GUA CUG
C. GTA ATG ATG GUA CUG D. None of these
29. Which of the following is correct according to Chargaff’s rules?
A. A+C=G+T B. A+T=G+C C. A+T=T+C d) All the above

30. Who discovered DNA polymerase?


A. Kornberg B. Chargaff C. Nathans D. Smith

31. Which of the viruses exhibits reverse transcription process?


A. Polio virus B. Tobacco mosaic virus C. Retro virus D. Hepatitis B virus

32. Where is the location of promoter in the transcription unit?


A. Towards 5’ end of template strand
B. Towards 3’ end of template strand
C. Towards 5’ end of coding strand
D. Towards 3’ end of coding strand

33. Which molecule acts as an adaptor during translation?


A. mRNA B. rRNA C.tRNA D.hnRNA

34. Who confirmed transforming principle experimentally?


A. Oswald Avery B. Collin McLeod C. Maclynn McCarty D. All of them together

35. What is the product of metabolism of galactose in lac operon?


A. Glucose + Lactose B. Glucose + Glucose C. Glucose + Fructose D. None

36. What is the name of segment of DNA capable of producing a polypeptide chain
A. Recon B. Cistron C. Muton D. None of these

37. Who experimentally proved semi conservative model of DNA replication


A. Meselson & Stahl B. Frederic Griffith C. Watson & Crick D. Chargaff

38. The codon AUG stands for which amino acid


A. Tryptophan B. Glycine C. Lysine D. Methionine

39. How many sense codons are there in genetic code


A. 64 B. 61 C. 62 D. 60

40. When did human genome project start?


A. 1989 B. 1990 C. 1988 D. None

41. Where is the location of terminator in the transcription unit


E. Towards 5’ end of template strand
F. Towards 3’ end of template strand
G. Towards 5’ end of coding strand
H. Towards 3’ end of coding strand

42. Who named the term nucleic acid to the content of chromatin?
A. Frederic Altmann B. Oswald Awery C. Gregor Mendel D. None

43. Which enzymes prevents the binding of unwound DNA strands


A. DNA ligase B. DNA polymerase C. SSB protein D. Helicase

44. RNA polymerase III transcribes


A. tRNA B. mRNA C. hnRNA D. rRNA

45. Degeneracy of genetic code is due to


A. First nitrogen base
B. Second nitrogen base
C. Third nitrogen base
D. First & second nitrogen base

46. Number of base pairs in a mini satellite is approximately


A. 6-12 bp B. 12-18 bp C. 18- 24 bp D. None

47. The post transcriptional process involves


A. Splicing B. Tailing C. Capping D. All

48. How many naturally occurring amino acids are there


A. 20 B. 21 C.22 D. None

49. How many stop codons are there?


A. 3 B.2 C. 4 D. 5

50. Which gene produces permease in Lac operon?


A. Z-gene B. A- gene C. Y-gene D. P-gene

****************************************
ANSWERS KEYS

1. B 18. D 35. D
2. B 19. A 36. B
3. B 20. A 37. A
4. B 21. A 38. D
5. B 22. D 39. B
6. D 23. B 40. B
7. B 24. D 41. B
8. C 25. D 42. D
9. A 26. B 43. C
10. C 27. B 44. A
11. A 28. D 45. C
12. A 29. B 46. D
13. C 30. A 47. D
14. B 31. A 48. A
15. B 32. A 49. A
16. C 33. C 50. C
17. B 34. D

Rajeshkumar
Principal
K V No.1, Devlali

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