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Simple X-Linked Genetics

This document discusses genetics concepts through examples involving sex-linked traits in fruit flies and humans. It examines crosses between parents with different genotypes to determine the expected ratios of offspring phenotypes. Key points covered include sex linkage of eye color in fruit flies, X-linked inheritance of hemophilia in humans, and codominance of fur color genes in calico cats. Offspring ratios are presented through genetic crosses and used to calculate expected percentages.

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Kalina Dimov
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© © All Rights Reserved
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Download as PDF, TXT or read online on Scribd
480 views

Simple X-Linked Genetics

This document discusses genetics concepts through examples involving sex-linked traits in fruit flies and humans. It examines crosses between parents with different genotypes to determine the expected ratios of offspring phenotypes. Key points covered include sex linkage of eye color in fruit flies, X-linked inheritance of hemophilia in humans, and codominance of fur color genes in calico cats. Offspring ratios are presented through genetic crosses and used to calculate expected percentages.

Uploaded by

Kalina Dimov
Copyright
© © All Rights Reserved
Available Formats
Download as PDF, TXT or read online on Scribd
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Kalina Dimov

Name _____________________________

Genetics: X Linked Genes


****In fruit flies, eye color is a sex linked trait. Red is dominant to white ****

1. What are the sexes and eye colors of flies with the following genotypes:

XRXr pink - female


_____________ XRY red - male
____________ XrXr white - female
____________
XRXR red - female
____________ XrY white -male
____________

2. What are the genotypes of these flies:


X^rY X^RX^r
white eyed, male ____________ red eyed female (heterozygous) ________
white eyed, female ___________
X^rX^r X^RY
red eyed, male ___________

3. Show the cross of a white eyed female X r X r with a red-eyed male X R Y .


X^r X^r

X^R X^RX^r X^RX^r

Y X^rY X^rY

4. Show a cross between a pure red eyed female and a white eyed male.
What are the genotypes of the parents:
X^RX^R
___________& X^rY
_______________
X^R X^R
X^r X^RX^r X^RX^r How many are:
0
white eyed, male ____
Y X^RY X^RY white eyed, female ____
0
red eyed, male ____
2
red eyed, female ____
2

5. Show the cross of a red eyed female (heterozygous) and a red eyed male. What are the genotypes
of the parents?
X^RX^r
___________ X^RY
& ________________

How many are:


X^R X^r 1
white eyed, male____
X^R X^RX^R X^RX^r 0
white eyed, female ___
1
red eyed, male ____
Y X^RY X^rY
2
red eyed, female ____

Math: What if in the above cross, 100


males were produced and 200 females.
How many total red-eyed flies would there
be?
150
____________
6. In humans, hemophilia is a sex linked trait. Females can be normal, carriers, or have the disease.
Males will either have the disease or not (but they won’t ever be carriers)
= female, normal
= male, normal

= female, carrier
= male, hemophiliac

= female, hemophiliac

Show the cross of a man who has hemophilia with a woman who is a carrier.
X^H X^h
X^h X^HX^h X^hX^h
Y X^HY X^hY

50%
What is the probability that their children will have the disease? __________

7. A woman who is a carrier marries a normal man. Show the cross. What is the probability
that their children will have hemophilia? What sex will a child in the family with hemophilia
be? X^H X^h
Probability : 25%
X^H X^HX^H X^HX^h
Male
Y X^HY X^hY

8. A woman who has hemophilia marries a normal man. How many of their children will have
hemophilia, and what is their sex?
X^h X^h 50% of their children will be hemophilic.
X^H X^HX^h X^HX^h Male

Y X^hY X^hY

9. In cats, the gene for calico (multicolored) cats is codominant. Females that receive a B and an R
gene have black and oRange splotches on white coats. Males can only be black or orange, but never
calico.
Here’s what a calico female’s genotype would look like. XB XR
Show the cross of a female calico cat with a black male?
X^B X^R 25%
What percentage of the kittens will be black and male? _________
X^B X^BX^B X^BX^R 0%
What percentage of the kittens will be calico and male? _________
What percentage of the kittens will be calico and female? _________
50%
Y X^BY X^RY

10. Show the cross of a female black cat, with a male orange cat.
X^B X^B 50%
What percentage of the kittens will be calico and female? _____
X^BX^R black
What color will all the male cats be? ______
X^R X^BX^R

Y X^BY X^BY

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