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Maximum & Minimum Concentration During Multiple Dosing

1. The document discusses pharmacokinetic concepts related to multiple dosing including maximum and minimum drug concentrations, steady state concentrations, and drug accumulation. 2. Drug fluctuation is smallest when a drug is given extravascularly due to continuous absorption, whereas intravenous bolus dosing sees the greatest fluctuation. 3. The average drug concentration at steady state is determined by the maintenance dose amount absorbed per interval, the dosing interval, and the drug's elimination half-life.

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HUNOOR SHAIK
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151 views

Maximum & Minimum Concentration During Multiple Dosing

1. The document discusses pharmacokinetic concepts related to multiple dosing including maximum and minimum drug concentrations, steady state concentrations, and drug accumulation. 2. Drug fluctuation is smallest when a drug is given extravascularly due to continuous absorption, whereas intravenous bolus dosing sees the greatest fluctuation. 3. The average drug concentration at steady state is determined by the maintenance dose amount absorbed per interval, the dosing interval, and the drug's elimination half-life.

Uploaded by

HUNOOR SHAIK
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Brophomauuhcs PhamocokintHos BP604T

Maximum nd Minimum Cmunbrghion duing


MulpDoAing Dr. Parjanya Shukla

Dr.M.P. 8tngh Clase


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Dr. Parjanga Shukla
&
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Hvraq Conuntraion and body Cmtant on Mulh


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* Sinu X = Va C
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