SAFETY DATA SHEET Version 6.

9
Revision Date 16.07.2021
according to Regulation (EC) No. 1907/2006 Print Date 04.05.2022
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers
Product name : Boric acid
Product Number : B7901
Brand : Sigma
Index-No. : 005-007-00-2
REACH No. : 01-2119486683-25-XXXX
CAS-No. : 10043-35-3

1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Inc.
3050 SPRUCE ST
ST. LOUIS MO 63103
UNITED STATES
Telephone : +1 314 771-5765
Fax : +1 800 325-5052
1.4 Emergency telephone
Emergency Phone # : 800-424-9300 CHEMTREC (USA) +1-703-
527-3887 CHEMTREC (International) 24
Hours/day; 7 Days/week

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Reproductive toxicity (Category 1B), H360FD
For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram

Signal word Danger

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 Hazard statement(s)
H360FD May damage fertility. May damage the unborn child.
Precautionary statement(s)
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and
understood.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection/ hearing protection.
P308 + P313 IF exposed or concerned: Get medical advice/ attention.
P405 Store locked up.
P501 Dispose of contents/ container to an approved waste disposal
plant.
Supplemental Hazard none
Statements
Restricted to professional users.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients

3.1 Substances
Formula : H3BO3
Molecular weight : 61,83 g/mol
CAS-No. : 10043-35-3
EC-No. : 233-139-2
Index-No. : 005-007-00-2
Component Classification Concentration
boric acid Included in the Candidate List of Substances of Very High Concern (SVHC)
according to Regulation (EC) No. 1907/2006 (REACH)
CAS-No. 10043-35-3 Repr. 1B; H360FD <= 100 %
EC-No. 233-139-2 Concentration limits:
Index-No. 005-007-00-2 >= 5,5 %: Repr. 1B,
H360FD;
For the full text of the H-Statements mentioned in this Section, see Section 16.

SECTION 4: First aid measures

4.1 Description of first-aid measures
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with
water/ shower. Consult a physician.

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 In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact
lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a
physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section
2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media
Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Borane/boron oxides
Not combustible.
Ambient fire may liberate hazardous vapours.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by
keeping a safe distance or by wearing suitable protective clothing.
5.4 Further information
Prevent fire extinguishing water from contaminating surface water or the ground water
system.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact.
Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures,
consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions
(see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area.
Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
7.1 Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands
and face after working with substance.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditions
Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible
only to qualified or authorized persons.
Moisture sensitive.
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

8.1 Control parameters
Ingredients with workplace control parameters
8.2 Exposure controls

Personal protective equipment

Eye/face protection
Use equipment for eye protection tested and approved under appropriate
government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L
This recommendation applies only to the product stated in the safety data sheet,
supplied by us and for the designated use. When dissolving in or mixing with other
substances and under conditions deviating from those stated in EN374 please
contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm

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 Break through time: 480 min
Material tested:KCL 741 Dermatril® L
Body Protection
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following
standards: DIN EN 143, DIN 14387 and other accompanying standards relating to
the used respiratory protection system.
Recommended Filter type: Filter type P3
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory
protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties
a) Appearance Form: crystalline
Color: white
b) Odor odorless
c) Odor Threshold Not applicable
d) pH 5,1 at 1,8 g/l at 25 °C

e) Melting Melting point/range: 160 °C - dec.

point/freezing point
f) Initial boiling point 300 °C
and boiling range
g) Flash point No data available
h) Evaporation rate No data available
i) Flammability (solid, The product is not flammable. - Flammability (solids)
gas)
j) Upper/lower No data available
flammability or
explosive limits
k) Vapor pressure < 0,1 hPa at 25 °C - Regulation (EC) No. 440/2008, Annex, A.4
l) Vapor density No data available
m) Density 1,49 g/cm3 at 23 °C
Relative density 1,49 at 23 °C - Regulation (EC) No. 440/2008, Annex, A.3
n) Water solubility 49,2 g/l at 20 °C - Regulation (EC) No. 440/2008, Annex, A.6-
completely soluble
o) Partition coefficient: log Pow: -1,09 at 22 °C - Regulation (EC) No. 440/2008, Annex,
n-octanol/water A.8 - Bioaccumulation is not expected.

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 p) Autoignition No data available
temperature
q) Decomposition No data available
temperature
r) Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
s) Explosive properties No data available
t) Oxidizing properties No data available
9.2 Other safety information
Dissociation constant 8,94 at 20 °C
- OECD Test Guideline 112

SECTION 10: Stability and reactivity

10.1 Reactivity
No data available
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.3 Possibility of hazardous reactions
Risk of explosion with:
Acetic anhydride
Violent reactions possible with:
strong oxidising agents
Bases

10.4 Conditions to avoid

Exposure to moisture.
no information available
10.5 Incompatible materials
No data available
10.6 Hazardous decomposition products
In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Rat - male and female - 3.450 mg/kg
Remarks: (ECHA)
LC50 Inhalation - Rat - male and female - 4 h - > 2,12 mg/l
(OECD Test Guideline 403)
LD50 Dermal - Rabbit - male and female - > 2.000 mg/kg
Remarks: (ECHA)
Skin corrosion/irritation
Skin - Rabbit
Result: No skin irritation - 24 h
Remarks: (ECHA)
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 Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation - 24 h
(OECD Test Guideline 405)
Respiratory or skin sensitization
Buehler Test - Guinea pig
Result: negative
(OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: sister chromatid exchange assay
Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation
Result: negative
Remarks: (ECHA)
Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative

Test Type: Micronucleus test

Species: Mouse

Application Route: Oral

Method: OECD Test Guideline 474
Result: negative
Carcinogenicity
No data available
Reproductive toxicity
May damage fertility.
May damage the unborn child.
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Oral - 2 yr - NOAEL (No observed adverse
effect level) - 17,5 mg/kg - LOAEL (Lowest observed adverse effect level) - 58,5 mg/kg

RTECS: ED4550000
Toxicity reported for borates in humans: ingestion or absorption may cause nausea,
vomiting, diarrhea, abdominal cramps, anderythematous lesions on the skin and mucous
membranes. Other symptoms include: circulatory collapse, tachycardia, cyanosis, delirium,

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 convulsions, and coma. Death has been reported to occur in infants from less than 5 grams
and in adults from 5 to 20 grams.
To the best of our knowledge, the chemical, physical, and toxicological properties have not
been thoroughly investigated.
Liver - Irregularities - Based on Human Evidence

SECTION 12: Ecological information

12.1 Toxicity
Toxicity to fish LC50 - Ptychocheilus lucius - 279 mg/l - 96 h
Remarks: (ECOTOX Database)

Toxicity to daphnia EC50 - Daphnia magna (Water flea) - 133 mg/l - 48 h

and other aquatic
invertebrates
12.2 Persistence and degradability
The methods for determining biodegradability are not applicable to inorganic substances.
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at
levels of 0.1% or higher.
12.6 Other adverse effects
No data available

SECTION 13: Disposal considerations

13.1 Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.

SECTION 14: Transport information

14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -

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14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user

Further information
Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This material safety data sheet complies with the requirements of Regulation (EC) No.
1907/2006.
Authorisations and/or restrictions on use
REACH - Candidate List of Substances of Very : boric acid
High Concern for Authorisation (Article 59).
REACH - Restrictions on the manufacture, : boric acid
placing on the market and use of certain
dangerous substances, preparations and articles
(Annex XVII)

Other regulations
Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or
stricter national regulations where applicable.
Take note of Dir 94/33/EC on the protection of young people at work.
15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out

SECTION 16: Other information

Full text of H-Statements referred to under sections 2 and 3.
H360FD May damage fertility. May damage the unborn child.
Further information
The above information is believed to be correct but does not purport to be all inclusive
and shall be used only as a guide. The information in this document is based on the
present state of our knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any guarantee of the properties of
the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any
damage resulting from handling or from contact with the above product. See
www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional
terms and conditions of sale.

Copyright 2020 Sigma-Aldrich Co. LLC. License granted to make unlimited paper copies
for internal use only.
The branding on the header and/or footer of this document may temporarily not visually
match the product purchased as we transition our branding. However, all of the

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 information in the document regarding the product remains unchanged and matches the
product ordered. For further information please contact [email protected].

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