Safeguard every outcome

with controlled phaco performance

The CENTURION® Vision System with ACTIVE SENTRY® Handpiece:*
• Reduces surge by detecting pressure and triggering
precise adjustments to ensure consistency4,6
• Maintains target IOP – regardless of PEL – with Active Fluidics™ Technology 4-6,15
• Maintains stability across a variety of vacuum levels5,6,16
• Reduces phaco procedure times, as well as fluid use9,10
• Protects eye from heat injury9,11,18
• INTREPID® Hybrid Tip helps reduce the risk of capsular tears and improves
safety in the OR 7

Contact your Alcon representative to learn more about bringing a new level of safety and efficiency to your procedures.

CENTURION® VISION SYSTEM IMPORTANT SAFETY INFORMATION

CAUTION: These products are CE Marked and comply with the regulations applicable to Medical Devices.
INDICATION: The CENTURION® Vision System is indicated for emulsification, separation, irrigation, and aspiration of cataracts, residual cortical material and lens epithelial cells, vitreous aspiration and cutting associated with anterior vitrectomy, bipolar coagulation, and
intraocular lens injection. The AutoSert® IOL Injector Handpiece is intended to deliver qualified AcrySof® intraocular lenses into the eye following cataract removal. The AutoSert® IOL Injector Handpiece achieves the functionality of injection of intraocular lenses. The AutoSert® IOL Injector Handpiece is indicated for use with the
AcrySof® lenses SN6OWF, SN6AD1, SN6AT3 through SN6AT9, as well as approved AcrySof® lenses that are specifically indicated for use with this inserter, as indicated in the approved labeling of those lenses.
WARNINGS: Appropriate use of CENTURION® Vision System parameters and accessories is important for successful procedures. Use of low vacuum limits, low flow rates, low bottle heights, high power settings, extended power usage, power usage during occlusion conditions (beeping tones), failure to sufficiently aspirate viscoelastic
prior to using power, excessively tight incisions, and combinations of the above actions may result in significant temperature increases at incision site and inside the eye, and lead to severe thermal eye tissue damage. Good clinical practice dictates the testing for adequate irrigation and aspiration flow prior to entering the eye. Ensure that
tubings are not occluded or pinched during any phase of operation. The consumables used in conjunction with ALCON® instrument products constitute a complete surgical system. Use of consumables and handpieces other than those manufactured by Alcon may affect system performance and create potential hazards.
AEs/COMPLICATIONS: Inadvertent actuation of Prime or Tune while a handpiece is in the eye can create a hazardous condition that may result in patient injury. During any ultrasonic procedure, metal particles may result from inadvertent touching of the ultrasonic tip with a second instrument. Another potential source of metal
particles resulting from any ultrasonic handpiece may be the result of ultrasonic energy causing micro abrasion of the ultrasonic tip.
ATTENTION: Refer to the Directions for Use and Operator’s Manual for a complete listing of indications, warnings, cautions and notes.

* Compared to previous generations of Alcon phaco systems. ** Compared to previous generations of Alcon phaco tips. *** Compared to Alcon coaxial I/A handpiece.
1. Centurion® Vision System Operating Manual. 2. Active Sentry® pressure sensing handpiece Directions for use. 3. Sharif-Kashani P, Fanney D, Injev V. Comparison of occlusion break responses and vacuum rise times of phacoemulsification systems. BMC Ophthalmol. 2014;14:96. 4. Alcon data on file, Ref. 02559, 03.05.2017. 5. Nicoli
CM, Dimalanta R, Miller K. Experimental anterior chamber maintenance in active versus passive phacoemulsification fluidics systems. J Cataract Refract Surg. 2016;42(1):157-162. 6. Thorne A. et al. Phacoemulsifier occlusion break surge volume reduction. J Cataract Refract Surg 2018; 44:1491–1496 7. Shumway C. Utility of a novel hybrid
phacoemulsification tip to prevent posterior capsule rupture. Presentation at ASCRS 2019, 3-7 May, San Diego. 8. Centurion® FMS pack directions for use. 9. Khokhar S, Aron N, Sen S, Pillay G, Agarwal E. Effect of balanced phacoemulsification tip on the outcomes of torsional phacoemulsification using an active-fluidics system. J Cataract
Refract Surg. 2017;43(1):22-28. 10. Solomon et al. Clinical study using a new phacoemulsification system with surgical intraocular pressure control. J Cataract Refract Surg 2016; 42:542–549. 11. Zacharías J. Laboratory assessment of thermal characteristics of three phacoemulsification tip designs operated using torsional ultrasound.
Clinical Ophthalmology 2016:10 1095–1101. 12. Demircan, et al. Comparison of 45-degree Kelman and 45-degree balanced phaco tip designs in torsional microcoaxial phacoemulsification, Int J Ophthalmol 2015;8(6):1168-1172. 13. Lehmann R. Automated Patient Eye Level by Sensor-based handpiece. Presentation at ASCRS 2019, 3-7
May, San Diego. 14. Crandall AS. Role of Incision Leakage in Anterior Chamber Stability in Different Phacoemulsifier Systems. Presentation at ASCRS 2019, 3-7 May, San Diego. 15. Boukhny M, Sorensen G, Gordon R. A novel phacoemulsification system utilizing feedback based IOP target control. ASCRS-ASOA Symposium and Congress;
April 25-29, 2014; Boston, MA. 16. Aravena et al. Aqueous volume loss associated with occlusion break surge in phacoemulsifiers from 4 different manufacturers. J Cataract Refract Surg 2018; 44:884–888. 17. Vasavada AR, et al. Comparison of torsional and microburst longitudinal phacoemulsification: a prospective, randomized,
masked clinical trial. Ophthalmic Surg Lasers Imaging. 2010;41(1):109-114. 18. Zacharías J. Comparative thermal characterization of phacoemulsification probes operated in elliptical, torsional and longitudinal ultrasound modalities. ASCRS-ASOA Symposium and Congress; April 25-29, 2014; Boston, MA. 19. Intrepid® Transformer I/A
handpiece Directions for use. 20. Allen D, Habib M, Steel D. Final incision size after implantation of a hydrophobic acrylic aspheric intraocular lens: new motorized injector versus standard manual injector. J Cataract Refract Surg. 2012;38(2):249-255. 21. Johansson C. Comparison of motorized IOL insertion to traditional manual IOL
delivery. ASCRS-ASOA Symposium and Congress; March 25-29, 2011; San Diego, CA.

© 2019 Alcon 9/19 EMEA-ASP-1900001

 Centurion ®

Vision System With ACTIVE SENTRY® Handpiece

ADVANCED CONTROL CENTER,

AT YOUR FINGERTIPS

The Centurion® Vision System with ACTIVE SENTRY® handpiece places advanced science at your fingertips,
with an integrated fluidics pressure sensor, delivering improved safety, consistency and control.1-8
Smooth phaco performance
that helps to optimize surgical outcomes

The CENTURION® Vision System with ACTIVE SENTRY® Handpiece The CENTURION® Vision System with
is redefining phacoemulsification performance1,2 – its innovative ACTIVE SENTRY® Handpiece is supported
design and real-time surge reduction supports you to further ensure by advanced procedural technologies
safety, consistency and control for cataract patients.* designed to add even more efficiency to
your phaco experience.1,2,8,**

I M P R O V E D S A F E T Y, C O N S I S T E N C Y A N D C O N T R O L IMPROVED EFFICIENCY

•F
 ast responsiveness3,4 • Streamlined phacoemulsification3-5,7-12
- The ACTIVE SENTRY® Handpiece is the first and only phaco - INTREPID® BALANCED Tip designed
handpiece equipped with a fluidics pressure sensor for better efficiency**:
• Enhanced surge reduction4-6 - Improved torsional performance9,11,12
- The handpiece communicates with hardware and software - Shorter ultrasound and aspiration
for more consistent procedures times9,10,12
- Reduced energy use3-5
• Stability from start to finish3-5
- Minimal heat production11
-C
 ENTURION® Active Fluidics™ Technology dynamically
- Less fluid needed10,12
manages IOP in a wide range of surgical settings
• Designed to enhance safety7,8 - INTREPID® Hybrid Tip:
- The INTREPID® Hybrid Tip incorporates proprietary -D
 esigned to provide efficient
polymer technology to reduce damage to the capsular performance similar to the
bag and other tissues INTREPID® BALANCED Tip7,8
INTREPID® BALANCED Tip INTREPID® Hybrid Tip
ACTIVE SENTRY® HANDPIECE

Scientific innovation
has never been so uneventful
Designed to reduce post-occlusion surge, the ACTIVE SENTRY® Handpiece helps
to maintain stability in the anterior chamber and improve consistency
during phaco procedure4,6. With less variance in surge amplitude, you’ll be
able to minimize yet another variable in the surgical experience.

The first and only phaco handpiece

with an integrated fluidics pressure sensor.
 ACTIVE SENTRY® HANDPIECE
The ACTIVE SENTRY® Handpiece alerts
Active Fluidics™ Technology as fluctuation
occurs in the anterior chamber, triggering
Simulated Eye Volume After Occlusion Break4
(IOP 50 mmHg; Vac Setting 500 mmHg; immediate adjustments designed to
IOP 50 mmHg
Asp
VacRate
Setting40
500 cc/min)
mmHg stabilize the anterior chamber and
Asp Rate 40 cc/min
0.02
ensure consistency.1,4,6
0
Simulated Eye Volume (cc)

-0.02

-0.04

-0.06

-0.08

-0.10
Technical Overview, Surge Mitigation:
ACTIVE SENTRY® Handpiece4,6
-0.12 (Surge Volume, IOP Setpoint = 55 mmHg)
-0.14
0.5 1 1.5

Time After Occlusion Break (sec)

ACTIVE SENTRY® Handpiece INFINITI® INTREPID® PLUS

The ACTIVE SENTRY® Handpiece provides real-time,

improved surge reduction after occlusion breaks,
ensuring more consistent volume and IOP.4,6
ACTIVE SENTRY® HANDPIECE

Mitigating risks to safeguard your outcomes13,14

Maintains target IOP1,15 Compensates for average incision leakage1,14

• Sensor automatically recognizes patient eye • Sensor automatically detects difference in aspiration
level (PEL)13 and irrigation rates1,14
• Eliminates need for manual adjustments13 • Increases irrigation flow for consistent pressure1,14

IOP Error vs. PEL Offset13 IOP Error vs. Incision Leakage14
 The CENTURION® Vision System with
ACTIVE SENTRY® Handpiece consistently
preserves more volume, for less surge
Engineered for safe, controlled phaco performance
and greater safety.3-6,16
across a variety of vacuum levels3-6,16

Phakic Eye Testing16 Aphakic Eye Testing16

† †

Table 1: Phakic human eye aqueous volume loss associated with occlusion break surge16

Vacuum Limit Surge Volume Percent Volume Loss in Percent Volume Loss in
(mmHg) (µL) Phakic Eye Aphakic Eye
CENTURION® Vision System 200–600 17–77 7%–31% 4%–17%
AMO Signature †
200–600 30–103 12%–41% 7%–22%
DORC EVA †
200–600 47–165 19%–66% 10%–36%
B&L Stellaris PC† 200–400 67–163 27%–65% 15%–35%
† Trademarks are the property of their respective owners.
The evolution of fluidics in phaco

Gravity fluidics
Uses bottle height to regulate IOP5

Pressurized fluidics
Uses air pump to achieve irrigation pressure in bottle5

Active Fluidics™ Technology

Uses compression plates to maintain surgeon-selected target IOP1,5

Active Fluidics™ Technology with ACTIVE SENTRY® Handpiece

Combines Active Fluidics™ Technology with fluidics pressure
sensor in handpiece1,2
 Active Fluidics™ Technology with ACTIVE SENTRY® Handpiece1,2

3. Active Fluidics™ Technology

Uses compression plates to adjust
pressure on BSS® irrigating solution bag,
compensating for changes in the eye

ACTIVE FLUIDICS ™ TECHNOLOGY

1. Fluidics pressure sensor Detects
changes in anterior chamber stability
as they occur

2. ACTIVE SENTRY® Handpiece

Signals to CENTURION® Vision System
4. QuickValve™ technology
hardware and software that adjustments
Releases fluid into aspiration line
are needed to maintain consistent IOP
ACTIVE FLUIDICS ™ TECHNOLOGY

Chamber stability throughout whole

phaco procedure4-6,15,16
Active Fluidics™ Technology uses compression plates to apply
and release pressure on the BSS® irrigating solution bag as changes
in the anterior chamber are detected, actively working to maintain
target IOP.1,5,15
• Compensates for varying aspiration flow rates in
real time5,15
• Less IOP fluctuation versus gravity and pressurized
fluidics5,15

“With the CENTURION® Vision System with

ACTIVE SENTRY® Handpiece, there was lesser
movement of the posterior capsule with a
faster recovery of chamber and bag volume.”
– Cesar Espiritu, MD, vice-chairman of the
Manila Doctors Hospital ophthalmology department
Paid Alcon Consultant
IOP as Aspiration Rate Rises15 IOP vs. Aspiration Flow Rate15
Gravity vs. Active Fluidics™ Pressurized Bottle Compared with Active Fluidics™

† Trademarks are the property of their respective owners.

Flow rates vary during every case. Unlike gravity and pressurized
fluidics, Active Fluidics™ Technology detects and compensates IOP
fluctuations to help maintain surgeon-selected IOP.5,15
CENTURION® ENERGY DELIVERY

Improved efficiency to reduce ultrasound energy,

aspiration fluid used and aspiration time9-11,17
The efficient combination of OZil® technology and innovative fluidics streamlines
phacoemulsification procedures.9-11,17
• Accelerated cataract removal*9,10 • Reduced repulsion17
• Reduced energy output9,10 • Less fluid use9,10
• Enhanced torsional efficiency9-11,17

Cumulative Dissipated
Energy Used Energy10 Aspiration
FluidFluid
Used Used
10
Aspiration
TimeTime
10

8 60 200

39% 11.6%
mL
Used, mL
9%

seconds
Time, seconds
7.11 52.68

Fluid Used,
percent-seconds
CDE, percent-seconds

6 150 167.63
Reduced 40 46.56 Reduction 151.85 Faster
Aspiration Fluid

Aspiration Time,
4 100
Aspiration
4.32

Aspiration
20
CDE,

2 50

0 0 0
CENTURION®® INFINITI®® CENTURION®® INFINITI®® CENTURION®® INFINITI®®
Configuration Configuration Configuration Configuration Configuration Configuration
(n=98) (n=97) (n=98) (n=97) (n=98) (n=97)

Group difference (95% confidence interval): Group difference (95% confidence interval): Group difference (95% confidence interval):
–2.79 (–3.44 to –2.13) percent-seconds; –6.12 (–9.82 to –2.43) mL; data reflect least –15.78 (–26.49 to –5.07) seconds; data reflect
data reflect least squares mean ± standard error. squares mean ± standard error. least squares mean ± standard error.

CENTURION® Configuration: CENTURION® Vision System, 45° BALANCED Tip with INTREPID® Ultra Sleeve
INFINITI® Configuration: INFINITI® Vision System, 45° Mini Flared Kelman with Ultra Sleeve
*As compared to the INFINITI® Vision System, bottle gravity system.
 Ellips FX† IR Energy delivery designed to protect the cornea and
Temperature Recording18 anterior chamber9
Versus traditional and Ellips FX† ultrasound modalities,
OZil® phaco and the BALANCED Tip deliver18:
• 60% less temperature rise18
• Safer heat transfer18

Temperature Rise
Under Occlusion & Load18

Temporal plot of
temperature at incision

CENTURION® ENERGY DELIVERY

OZil® Torsional IR
Temperature Recording18

Temporal plot of
temperature at incision

† Trademarks are the property of their respective owners.

SAFETY, EFFICIENCY

INTREPID® Hybrid Tip is designed

to enhance safety 7,8
Elevating the patient protection of the INTREPID® BALANCED Tip
with proprietary polymer technology

Two trusted technologies — one innovative design for reducing damage to the
capsular bag and other tissues7:

• Rounded polymer edge designed to reduce the risk of capsular tears7,8

• Cutting performance suitable for cataract densities up to 3+

• Fluidics performance and configuration similiar

to the INTREPID® BALANCED Tip

INTREPID® BALANCED Tip INTREPID® Hybrid Tip

Optimal performance through versatile phaco technology

Efficiency at your fingertips

INTREPID® BALANCED Tip offers**:
• More lateral movement at tip, less shaft movement at incision site9
• Minimal heat production11
• Minimized corneal stromal changes and complications9
• Alternative “straight” tip for torsional phaco

Adaptability for a variety of cases

INTREPID® Transformer I/A Handpiece allows for:
• Coaxial or bimanual cortical removal19
• Easier transitions with an all-in-one handpiece***

More control throughout the procedure

INTREPID® AutoSert® Handpiece delivers:20,21

IMPROVED SAFETY, EFFICIENCY

• Less force to the eye
• Better wound integrity
• Less incisional stretching
• Minimal wound disruption and trauma