Biochemistry

Placement – First Year Time: Theory – 30 Hours

Course Description : The Course is designed to assist the students to acquire knowledge of the normal biochemical
composition and functioning of human body and understand the alteration in biochemistry in diseases for practice of
nursing.

Unit Time Learning Objectives Content Teaching Learning Assessment

(Hrs) Activities methods
I 3  Describe the Introduction  Lecture  Short answer
structure  Definition and significance in nursing discussion using questions
Composition and  Review of structure, Composition charts, slides  Objective
functions of cell and functions of cell  Demonstrate type
 Differentiate  Prokaryote and Eukaryote cell use of microscope
between Prokaryote organization
and Eukaryote cell  Microscopy
 Identify techniques
of Microscopy
II 6  Describe the Structure and functions of Cell membrane  Lecture discussion  Short
Structure and  Fluid mosaic model tight junction, Answers
functions of Cell Cytoskeleton  Objective
membrane  Transport mechanism: diffusion, Type
osmosis, filtration, active channel,
sodium pump
 Acid base balance-maintenance &
diagnostic tests
 PH buffers
III 6  Explain the Composition and metabolism of  Lecture discussion  Short Answer
metabolism of Carbohydrates  Demonstration of question
carbohydrates  Types, structure, composition and uses blood glucose  Objective
 Monosaccharides, Disaccharides, monitoring Type
 Polysaccharides, Oligosaccharides
 Metabolism
 Pathways of glucose:
- Glycolysis
- Gluconeogenesis: Cori’s cycle,
Tricaboxylie acid (TCA) cycle
- Glycogenolysis
- Pentose phosphate pathways (Hexose
mono phosphate)
 Regulation of blood glucose level
Investigations and their interpretations
IV 4  Explain the Composition and metabolism of Lipids  Lecture discussion  Short Answer
metabolism of Lipids  Types, structure, composition and uses of using charts question
fatty acids  Demonstration of  Objective
 Nomenclature, Roles and Prostaglandins laboratory tests Type
 Metabolism of fatty acid
 Breakdown
 Synthesis
 Metabolism of triacylglycerols
 Cholesterol metabolism
 Biosynthesis and its Regulation
- Bile salts and bilirubin
- Vitamin D
- Steroid hormones
 Lipoproteins and their functions:
 VLDSs- IDLs, LDLs and HDLs
 Transport of lipids
 Atherosclerosis, Investigations and their
interpretations

V 6  Explain the Composition and metabolism of Amino acids  Lecture discussion  Short Answer
metabolism of Amino and Proteins using charts question
acids and Proteins  Types, structure, composition and uses of  Demonstration of  Objective
Amino acids and Proteins laboratory tests Type
  Metabolism of Amino acids and Proteins
 Protein syntheses, targeting and
glycosylation
 Chromatography
 Electrophoresis
 Sequencing
 Metabolism of Nitrogen
 Fixation and Assimilation
 Urea Cycle
 Hemes and chlorophylls
 Enzymes and co-enzymes
 Classification
 Properties
 Kinetics and inhibition
 Control
Investigations and their interpretations

VI 2  Describe types, Composition of Vitamins and minerals  Lecture Discussion  Short answer
composition and  Vitamins and minerals: using charts questions
utilization of  Structure  Demonstration of  Objective
Vitamins & minerals  Classification laboratory tests type
 Properties
 Absorption
 Storage & transportation
 Normal concentration Investigations and
their interpretations

VII 3  Describe Immuno- Immunochemistry  Lecture discussion  Short answer

chemistry  Immune response,  Demonstrate questions
 Structure and classification of laboratory tests  Objective
immunoglobins type
 Mechanism of antibody production
 Antigens: HLA typing.
 Free radical and Antioxidants.
 Specialised Protein: Collagen, Elastin,
Keratin, Myosin, Lens Protein.
 Electrophoretic and Quantitative
determination of immune-oglogins
– ELISA ets.
Investigations and their interpretations