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RDU3

This document provides an introduction to a study evaluating the degree of rational drug use at Mbarale Regional Referral Hospital in Eastern Uganda. Rational drug use refers to patients receiving appropriate and affordable medicines tailored to their condition. Irrational drug use, which is not compliant with rational standards, can lead to increased antimicrobial resistance, costs, and adverse health outcomes. The study aims to assess rational drug use at the hospital using WHO indicators and identify factors influencing drug use to propose targeted interventions.

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15 views3 pages

RDU3

This document provides an introduction to a study evaluating the degree of rational drug use at Mbarale Regional Referral Hospital in Eastern Uganda. Rational drug use refers to patients receiving appropriate and affordable medicines tailored to their condition. Irrational drug use, which is not compliant with rational standards, can lead to increased antimicrobial resistance, costs, and adverse health outcomes. The study aims to assess rational drug use at the hospital using WHO indicators and identify factors influencing drug use to propose targeted interventions.

Uploaded by

aine
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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A STUDY TO EVALUATE THE DEGREE OF RATIONAL DRUG USE USING WHO

INDICATORS IN MBALE REGIONAL REFERRAL HOSPITAL, EASTERN UGANDA

TABLE OF CONTENT

INTRODUCTION

BACKGROUND

Rational Drug Use refers to patients getting medicines appropriate to their individual clinical
conditions, in patient-tailored doses, for an adequate time and at lowest cost to them and their
community (WHO, 2005).

For Rational Drug Use to be ensured, the physician, dispenser and patient should play their part
appropriately. The physician comes up with the correct diagnosis and suggests safe, effective and
affordable medication for the benefit of the patient. Dispenser practices good stock management,
provides a right drug to the right patient in right formulation and dosage, proper counselling and
clear instructions. Then the patient complies and adheres to the provided medication (Mamo and
Alemu, 2020).

On the other hand, Irrational Drug Use is the use of medicine in a way that is not compliant with
Rational Drug Use. Examples of Irrational Drug Use include; polypharmacy, inappropriate
antimicrobial use, injections overuse, inappropriate self-medication with prescription-only
medicines and failure to prescribe in accordance with Clinical Guidelines (Sema et al. 2021).

Irrational Drug Use has been reported worldwide with the prevalence highest in Sub-Saharan and
low income countries with prevalence of 89% in Tanzania (Mboya et al., 2018), 51.4% in
Zambia (Lukali and Mchelo, 2015), and 23.3% in Egypt (Sabry et al., 2014).

This always results into rapid emergency of anti-microbial resistance, increased mortality and
morbidity, high drug therapy costs, increased occurrence of preventable adverse drug reactions,
drug interactions and poor patient adherence (Sisay, 2017).

To avoid these Irrational Drug Use consequences, a country and its healthy facilities must have
interventions such as; use of Clinical Guidelines, development and use of National Essential
Medicines List, establishment of Drug And Therapeutics Committees, continuing in-service
medical education, public education about medicines, avoidance of perverse financial incentives
and sufficient government expenditure to ensure availability of medicines and staff (WHO,
2021).

This study will evaluate the degree of rational drug use in MRRH and factors contributing to
that, then its findings will be used to propose facility-tailored interventions to promote rational
drug use.

PROBLEM STATEMENT

JUSTIFICATION

RESEARCH QUESTIONS

RESEARCH OBJECTIVES

CONCEPTUAL FRAMEWORK

LITERATURE REVIEW

METHODOLOGY

STUDY DESIGN

STUDY SETTING

STUDY PERIOD

STUDY POPULATION

SAMPLE SIZE CALCUTION

SAMPLING PROCEDURE

DATA COLLECTION PROCEDURE


DATA COLLECTION TOOLS

DATA ANALYSIS

ETHICAL CONSIDERATION

REFERENCES

APPENDICES

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