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CASP-Diagnostic-Checklist 2018 Word

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FADIL ABDULLAH
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130 views

CASP-Diagnostic-Checklist 2018 Word

Uploaded by

FADIL ABDULLAH
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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CASP Checklist: 12 questions to help you make sense of a Diagnostic Test study

How to use this appraisal tool: Three broad issues need to be considered when appraising a
trial:

Are the results of the study valid? (Section A)


What are the results? (Section B)
Will the results help locally? (Section C)

The 12 questions on the following pages are designed to help you think about these issues
systematically. The first three questions are screening questions and can be answered quickly.
If the answer to both is “yes”, it is worth proceeding with the remaining questions. There is
some degree of overlap between the questions, you are asked to record a “yes”, “no” or “can’t
tell” to most of the questions. A number of italicised prompts are given after each question.
These are designed to remind you why the question is important. Record your reasons for
your answers in the spaces provided.

About: These checklists were designed to be used as educational pedagogic tools, as part of a
workshop setting, therefore we do not suggest a scoring system. The core CASP checklists
(randomised controlled trial & systematic review) were based on JAMA 'Users’ guides to the
medical literature 1994 (adapted from Guyatt GH, Sackett DL, and Cook DJ), and piloted
with health care practitioners.
For each new checklist, a group of experts were assembled to develop and pilot the checklist
and the workshop format with which it would be used. Over the years overall adjustments
have been made to the format, but a recent survey of checklist users reiterated that the basic
format continues to be useful and appropriate.
Referencing: we recommend using the Harvard style citation, i.e.: Critical Appraisal Skills
Programme (2018). CASP (insert name of checklist i.e. Diagnostic Test Study) Checklist.
[online] Available at: URL. Accessed: Date Accessed.

©CASP this work is licensed under the Creative Commons Attribution – Non-Commercial-
Share A like. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-
sa/3.0/ www.casp-uk.net

Critical Appraisal Skills Programme (CASP) part of OAP Ltd www.casp-uk.net


Paper for appraisal and reference:
………………………………………………………………………………………………………
Section A: Are the results of the trial valid?

1. Was there a clear question Yes HINT: A question should include


for the study to address? information about
Can’t Tell • the population
• the test
No  the setting
• the outcomes

Comments:

4. Was there a comparison Yes HINT: Is this reference test(s) the best
with an appropriate available indicator in the circumstances
reference standard? Can’t Tell

No

Comments:

Is it worth continuing?

5. Did all patients get the Yes HINT: Consider


diagnostic test and • were both received regardless of the
reference standard? Can’t Tell results of the test of interest
 Check the 2x2 table (verification
No bias)

Comments:

4. Could the results of the test Yes HINT: Consider

2
have been influenced by the • was there blinding
results of the reference Can’t Tell  were the tests performed
standard?
independently
No  review bias

Comments:

5. Is the disease status of the Yes HINT: Consider


tested population clearly • presenting symptoms
described? Can’t Tell  disease stage of severity
 co-morbidity
No
 differential diagnoses (spectrum
bias)

Comments:

6. Were the methods for Yes HINT: Consider


performing the test described in • was a protocol followed
sufficient detail?
Can’t
Tell
No

Comments:

Section B: What are the results?

7. What are the results? HINT: Consider


 are the sensitivity and
specificity and/or likelihood

3
ratios presented
 are the results presented in
such a way that we can work
them out
Comments:

8. How sure are we about the results? HINT: Consider


Consequences and cost of alternatives  could they have occurred by chance
performed?  are there confidence limits
 what are they

Comments:

Section C: Will the results help locally?


Consider whether you are primarily interested in the impact on a population or individual level

9. Can the results be applied to Yes HINT: Do you think your


your patients/the population patients/population are so different from
of interest? Can’t Tell those in the study that the results cannot be
applied, such as age, sex, ethnicity and
No spectrum bias

Comments:

10. Can the test be applied to Yes HINT: Consider


your patient or population of  resources and opportunity costs
interest? Can’t Tell  level and availability of expertise
required to interpret the tests
No

4
 current practice and availability of
services

Comments:

11. Were all outcomes Yes HINT: Consider


important to the individual  will the knowledge of the test result
or population considered? Can’t Tell improve patient wellbeing
 will the knowledge of the test result
No lead to a change in patient management

Comments:

12. What would be the impact of using this test on your patients/population?

Comments:

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