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Kegg 01

KEGG is a database resource that integrates genomic, chemical, and systems information to understand biological functions from a molecular level. It represents biological systems using molecular networks and pathways captured from literature. KEGG contains sixteen interconnected databases that provide reference knowledge for interpreting genomes and molecular datasets.

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Quốc Anh Phạm
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40 views1 page

Kegg 01

KEGG is a database resource that integrates genomic, chemical, and systems information to understand biological functions from a molecular level. It represents biological systems using molecular networks and pathways captured from literature. KEGG contains sixteen interconnected databases that provide reference knowledge for interpreting genomes and molecular datasets.

Uploaded by

Quốc Anh Phạm
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© © All Rights Reserved
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Pham Quoc Anh

KEGG
KEGG is a database resource for understanding high-level functions and utilities of the
biological system, such as the cell, the organism and the ecosystem, from genomic and molecular-
level information. It is a computer representation of the biological system, consisting of molecular
building blocks of genes and proteins (genomic information) and chemical substances (chemical
information) that are integrated with the knowledge on molecular wiring diagrams of interaction,
reaction and relation networks (systems information). It also contains disease and drug information
(health information) as perturbations to the biological system.
KEGG is an integrated database resource consisting of sixteen databases shown below. They
are broadly categorized into systems information, genomic information, chemical information and
health information, which are distinguished by color coding of web page.
These databases contain various data objects for computer representation of the biological
systems. Thus, the database entry of each database is called the KEGG object, which is identified by
the KEGG object identifier consisting of a database-dependent prefix and a five-digit number.
The most unique data object in KEGG is the molecular networks -- molecular interaction,
reaction and relation networks representing systemic functions of the cell and the organism.
Experimental knowledge on such systemic functions is captured from literature and organized in the
following forms:
Pathway map - in KEGG PATHWAY (see: Pathway maps)
Brite hierarchy and table - in KEGG BRITE (see: Brite hierarchies)
Membership (logical expression) - in KEGG MODULE
Membership (simple list) - in KEGG DISEASE
These databases constitute the reference knowledge base for biological interpretation of
genomes and high-throughput molecular datasets through the process of KEGG mapping.

Reference:
(1) https://www.genome.jp/kegg/kegg1a.html

ALL RESOURCES WERE VIEWED ON FEBRUARY 27, 2023

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