The Nervous System
The Nervous System
DNA
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THE NERVOUS
SYSTEM
BY: SUE S. KALINAWAN, RN MAN
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MODULE OBJECTIVES
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LIST THE COMPONENTS OF THE NERVOUS
SYSTEM.
SYSTEM.
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FUNCTIONAL ORGANIZATION
02
03
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MAINTAINING HOMEOSTASIS.
RECEIVING SENSORY INPUT.
INTEGRATING INFORMATION.
CONTROLLING MUSCLES AND
GLANDS.
ESTABLISHING AND
MAINTAINING MENTAL
ACTIVITY.
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DIVISIONS OF THE
NERVOUS SYSTEM
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02
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CNS
PNS
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BRAIN The brain is located within the skull, and
the spinal cord is located within the vertebral
canal formed by the
vertebrae.
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Cells of the nervous system are called neurons.
NEURONS
Neurons send electrical messages from their cell
body to other cells with long extensions called axons.
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There are 12 pairs of nerves originating from the
CRANIAL AND SPINAL
NERVE brain, called cranial nerves, and 31 pairs of nerves
originating from the spinal cord, called spinal
nerves.
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SENSORY DIVISION The sensory division, or afferent (“toward”)
division, transmits electrical signals, called
action potentials, from sensory receptors in the
body to the CNS.
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The somatic nervous system allows you to decide
SOMATIC NERVOUS SYSTEM
to move your skeletal muscles, as when you raise
your hand. Voluntary (conscious) division.
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NEURON is called the neuron cell body, or soma;
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STRUCTURE as with any other type of cell, the cell
body’s nucleus is the source of
information for protein synthesis.
THREE
2. Dendrite. One type of cellular projection
PARTS
referring to its branching organization.
3. Axon. The other type of cellular
projection is called the axon, or nerve
fiber, referring to the straight alignment
and uniform diameter of most axons.
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The functional classification is based on the
TYPES OF
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NEURONS direction in which action potentials are
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conducted.
Sensory neurons (afferent neurons)
conduct action potentials toward the CNS;
FUNCTIONAL
CLASSIFICATION Motor neurons (efferent neurons) conduct
action potentials away from the CNS toward
muscles or glands.
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NEURONS
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Multipolar neurons have many dendrites
and a single axon.
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MAJOR PARTS
OF A NEURON
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GLIAL CELLS OF CNS. Glial cells are the major supporting cells in the CNS. Glial
cells help form a protective permeability barrier between the blood and the
brain and spinal cord, they phagocytize foreign substances, they produce
cerebrospinal fluid, and they form myelin sheaths around axons.
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Glial cells that are starshaped because cytoplasmic
ASTROCYTES
processes extend from the cell body.
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Schwann cells form myelin sheaths. However,
SCHWANN CELLS
unlike oligodendrocytes, each Schwann cell forms
a portion of the myelin sheath around only one
axon.
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Schwann cells or oligodendrocyte extensions repeatedly
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MYELINATED wrap around a segment of an axon to form a series of tightly
wrapped membranes rich in phospholipids, with little
cytoplasm sandwiched between the membrane layers.
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Unmyelinated axons are not devoid of myelin, as their
UNMYELINATED
name suggests. Instead, the axons rest in invaginations
of the Schwann cells or oligodendrocytes.
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axons are grouped together, forming bundles, while neuron cell bodies
and dendrites are grouped together.
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Gray Matter
cortex
DISTINCTIVE
nuclei
AREAS ganglion
White Matter
nerve tracts
nerves
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THE SYNAPSE
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The cell that transmits a signal The synapse is the junction between two cells
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toward the synapse is called the where they communicate with each other.
presynaptic cell (before the synapse),
and the target cell receiving the
signal is called the postsynaptic cell
(after the synapse). TYPES OF SYNAPSE
The average presynaptic neuron
synapses with about 1000 other
ELECTRICAL
neurons, but the average CHEMICAL
postsynaptic neuron has up to
10,000 synapses.
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junctions. The gap junctions allow a local
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current to flow directly from one cell to a
ELECTRICAL neighboring cell.
SYNAPSE
At these gap junctions, the membranes of
adjacent cells are separated by a 2 nm
gap spanned by structures called
connexons.
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end of an axon of the presynaptic cell.
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The space separating the axon ending and
CHEMICAL
the cell with which it synapses is the
SYNAPSE
synaptic cleft.
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1. Convergent pathways have many neurons synapsing with a few
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neurons.
2. Divergent pathways have a few neurons synapsing with many
neurons.
3. Reverberating circuits have collateral branches of postsynaptic
neurons synapsing with presynaptic neurons.
4. Parallel after-discharge circuits have neurons that stimulate
several neurons arranged in parallel that stimulate a common
output.
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THE
SPINAL
CORD
AND
SPINAL
NERVES
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SPINAL CORD
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The spinal cord is the major communication
link between the brain and the PNS inferior to
the head.
GENERAL
STRUCTURE It integrates incoming information and
produces responses through reflex
mechanisms.
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SPINAL CORD
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1. The spinal cord gives rise to 31 pairs of
spinal nerves. Nerves of the limbs enter and
leave the spinal cord at the cervical and
lumbosacral enlargements.
GENERAL
STRUCTURE
2. The spinal cord is shorter than the vertebral
column. Nerves from the end of the spinal
cord form the cauda equina.
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MENINGES OF Three meningeal layers surround the spinal
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cord:
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THE SPINAL
CORD
Dura mater. The most superficial and thickest
membrane. The dura mater forms a sac, often
MENINGEAL called the thecal sac, which surrounds the
LAYERS
spinal cord.
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THE SPINAL cord:
CORD
Arachnoid mater. The next deepest meningeal
MENINGEAL membrane is a very thin, wispy arachnoid
LAYERS mater.
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THE SPINAL cord:
CORD
Pia mater. The third, deepest meningeal layer,
MENINGEAL the pia mater is bound very tightly to the
LAYERS surface of the spinal cord.
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THE SPINAL pia mater is the subarachnoid space,
CORD
which contains weblike strands of the
arachnoid mater, blood vessels, and
MENINGEAL
LAYERS cerebrospinal fluid (CSF),
NOTE: The epidural space around the brain is only
a potential space. Epidural anesthesia of the
spinal nerves is often induced in women during
childbirth by injecting anesthetics into the
epidural space of the spinal cord.
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The basic structural unit of the nervous
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REFLEXES
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system is the neuron.
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REFLEXES (2) a sensory neuron,
(3) an interneuron,
(4) a motor neuron, and
BASIC
COMPONENTS (5) an effector organ.
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STRETCH REFLEX
Muscle spindles detect the stretch of skeletal
muscles and cause the muscle to shorten
reflexively.
GOLGI TENDON REFLEX
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1. Activation of pain receptors causes muscles to
contract and move some part of the body away
from a painful stimulus.
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by the endoneurium.
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SPINAL
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NERVES 2. Spinal nerves have specific cutaneous
distributions called dermatomes.
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SPINAL
NERVES AND
PLEXUSES
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Spinal nerves C1–C4 form the cervical
plexus, which supplies some muscles
CERVICAL and the skin of the neck and shoulder.
PLEXUS
The phrenic nerves innervate the
diaphragm.
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1. Spinal nerves C5–T1 form the brachial plexus,
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which supplies the upper limb.
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2. The axillary nerve innervates the deltoid and
BRACHIAL teres minor muscles and the skin of the
PLEXUS shoulder.
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surface of the forearm.
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5. The ulnar nerve innervates most of the
intrinsic hand muscles and the skin on the ulnar
BRACHIAL side of the hand.
PLEXUS 6. The median nerve innervates the pronator
and most of the flexor muscles of the forearm,
most of the thenar muscles, and the skin of the
radial side of the palm of the hand.
7. Other nerves supply most of the muscles that
act on the arm, the scapula, and the skin of the
medial arm and forearm.
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1. Spinal nerves L1–S4 form the lumbosacral
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plexus.
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LUMBAR AND 2. The obturator nerve supplies the muscles that
SACRAL
adduct the thigh and the skin of the medial
PLEXUSES
thigh.
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extend the thigh and flex the leg and the foot. It
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also supplies the plantar muscles and the skin
LUMBAR AND of the posterior leg and the sole of the foot.
SACRAL
PLEXUSES
5. The common fibular nerve and its branches
supply the short head of the biceps femoris, the
muscles that dorsiflex and plantar flex the foot,
and the skin of the lateral and anterior leg and
the dorsum of the foot.
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6. In the thigh, the tibial nerve and the common
LUMBAR AND fibular nerve are combined as the sciatic nerve.
SACRAL
PLEXUSES 7. Other lumbosacral nerves supply the lower
abdominal muscles, the hip muscles, and the
skin of the suprapubic area, external genitalia,
and upper medial thigh.
SHANOC
-
USB
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COCCYGEAL Spinal nerve S5 and the coccygeal nerve form
PLEXUS the coccygeal plexus, which supplies the
muscles of the pelvic floor and the skin over the
coccyx.
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SPINAL CORD
AND
DERMATOMAL
MAP
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BLADDER BREAK!
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BRAIN AND CRANIAL NERVES
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01
Development of the Central Nervous System
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02
Brainstem
03 Cerebellum
04 Diencephalon
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BRAIN AND CRANIAL NERVES
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05 Cerebrum
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06
Meninges, Ventricles, and Cerebrospinal Fluid
08 Cranial Nerves
The CNS forms from a flat plate of ectodermal
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tissue, the neural plate, on the dorsal surface of
CNS the embryo.
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DEVELOPMENT Just ventral to the neural plate is the notochord,
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a rod-shaped tissue that defines the axis of the
The brain and embryo and eventually gives rise to the central
spinal cord
develop from region of the intervertebral disks.
the neural tube. The lateral sides of the neural plate become
The ventricles elevated as waves, forming neural folds. The
and central crest of each fold is called a neural crest, and
canal develop the center of the neural plate becomes the
from the lumen neural groove.
of the neural
The neural folds move toward each other in the
tube.
midline and fuse to create a neural tube, which
gives rise to the CNS.
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The cephalic portion of the neural tube
becomes the brain, and the caudal portion
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becomes the spinal cord.
DEVELOPMENT
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Neural crest cells migrate away from the neural
The brain and crests to give rise to all the sensory, autonomic,
spinal cord and enteric neurons of the peripheral nervous
develop from system.
the neural tube. A series of pouches develops in the anterior
The ventricles
part of the neural tube, forming three brain
and central
canal develop regions in the early embryo:
from the lumen
of the neural a forebrain, or prosencephalon; a midbrain, or
tube. mesencephalon; and a hindbrain, or
rhombencephalon.
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1. The medulla oblongata is continuous with
the spinal cord and contains ascending and
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BRAINSTEM descending tracts.
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2. The pyramids are tracts controlling
voluntary muscle movement.
MEDULLA 3. The olives are nuclei that function in
OBLANGATA equilibrium, coordination, and modulation of
sound from the inner ear.
4. Medullary nuclei regulate the heart, blood
vessels, respiration, swallowing, vomiting,
coughing, sneezing, and hiccuping. The nuclei
of cranial nerves V, VII, and IX–XII are in the
medulla oblongata.
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1. The pons is superior to the medulla
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BRAINSTEM
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oblongata.
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BRAINSTEM
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2. The midbrain contains the nuclei for
cranial nerves III, IV, and V.
MIDBRAIN
3. The tectum consists of four colliculi. The
two inferior colliculi are involved in hearing,
and the two superior colliculi in visual
reflexes.
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4. The tegmentum contains ascending tracts
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BRAINSTEM and the red nuclei, which are involved in
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motor activity.
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scattered throughout the brainstem.
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Purkinje cells are the largest cells in the CNS.
CEREBELLUM
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2. The cerebellum has three parts, which
control balance, gross motor coordination,
RETICULAR and fine motor coordination.
FORMATION
3. The cerebellum corrects discrepancies
between intended movements and actual
movements.
4. The cerebellum can “learn” highly specific,
complex motor activities.
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1. The thalamus consists of two lobes
connected by the interthalamic adhesion.
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DIENCEPHALON The thalamus functions as an integration
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center.
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DIENCEPHALON The subthalamus is inferior to the thalamus
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and is involved in motor function.
SUBTHALAMUS Epithalamus
EPITHALAMUS
The epithalamus is superior and posterior to
the thalamus and contains the habenula,
which influences emotions through the sense
of smell. The pineal gland may play a role in
the onset of puberty.
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1. The hypothalamus, the most inferior
portion of the diencephalon, contains several
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DIENCEPHALON nuclei and tracts.
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2. The mammillary bodies are reflex centers
for olfaction.
HYPOTHALAMUS 3. The hypothalamus regulates many
endocrine functions. The pituitary gland
attaches to the hypothalamus.
4. The hypothalamus regulates body
temperature, hunger, thirst, satiety,
swallowing, and emotions.
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The longitudinal fissure divides the cerebrum into left and right
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hemispheres. Each hemisphere has five lobes.
CEREBRUM ■
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The frontal lobes are involved in smell, voluntary motor
function, motivation, aggression, and mood.
THE CORTEX OF ■ The parietal lobes contain the major sensory areas receiving
general sensory input, taste, and balance.
THE CEREBRUM
IS FOLDED INTO
■ The occipital lobes contain the visual centers.
RIDGES CALLED
■ The temporal lobes receive olfactory and auditory input and
are involved in memory, abstract thought, and judgment.
GYRI AND
GROOVES Tracts connect areas of the cortex within the same
CALLED SULCI, hemisphere (association fibers), between hemispheres
OR FISSURES. (commissural fibers), and with other parts of the brain and
the spinal cord (projection fibers).
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CEREBRUM
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Basal nuclei include the corpus striatum,
subthalamic nuclei, and substantia nigra.
BASAL NUCLEI
The basal nuclei are important in
controlling motor functions.
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CEREBRUM The limbic system includes parts of the
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cerebral cortex, basal nuclei, the
thalamus, the hypothalamus, and the
olfactory cortex.
LIMBIC SYSTEM
The limbic system controls visceral
functions through the autonomic nervous
system and the endocrine system and is
involved in emotions and memory.
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The brain and spinal cord are covered by the
dura, arachnoid, and pia mater.
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MENINGES
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The dura mater attaches to the skull and
has two layers that can separate to form
SURROUND AND dural sinuses.
PROTECT THE
BRAIN AND Beneath the arachnoid mater, the
SPINAL CORD subarachnoid space contains CSF, which
helps cushion the brain.
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connected to the third ventricle in the
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THE CNS FORMS diencephalon by the interventricular
AS A HOLLOW foramen.
TUBE THAT MAY
BE QUITE
REDUCED IN The third ventricle is connected to the
SOME AREAS OF fourth ventricle in the pons by the
THE ADULT CNS cerebral aqueduct. The central canal of
AND EXPANDED the spinal cord is connected to the fourth
IN OTHER AREAS. ventricle.
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CSF is produced from the blood in the
CEREBROSPINAL choroid plexus of each ventricle. CSF
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FLUID moves from the lateral to the third and
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A CLEAR FLUID then to the fourth ventricle.
SIMILAR TO
BLOOD SERUM From the fourth ventricle, CSF enters the
BUT WITHOUT
MOST OF THE subarachnoid space through three
PROTEINS. IT apertures.
PROVIDES A
PROTECTIVE CSF leaves the subarachnoid space
CUSHION through arachnoid granulations and
AROUND THE
CNS. returns to the blood in the dural venous
sinuses.
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REGIONS
OF THE
BRAIN
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BLOOD SUPPLY 1. The brain receives blood from the internal
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TO THE BRAIN carotid and vertebral arteries. The latter form
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THE BRAIN the basilar artery. The basilar and internal
REQUIRES A carotid arteries contribute to the cerebral
TREMENDOUS arterial circle. Branches from the circle and
AMOUNT OF basilar artery supply the brain.
BLOOD TO
MAINTAIN ITS
2. The blood-brain barrier is formed from the
NORMAL
FUNCTIONS endothelial cells of the capillaries in the brain
and the astrocytes in the brain tissue.
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CRANIAL
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NERVES
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CRANIAL NERVES
PERFORM SENSORY,
SOMATIC MOTOR,
AND
PARASYMPATHETIC
FUNCTIONS.
CHARACTERISTICS OF CRANIAL NERVES
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1. The olfactory (I) and optic (II) nerves 4. The trigeminal nerve (V) supplies the
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are involved in the senses of smell muscles of mastication, as well as a
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and vision, respectively. middle ear muscle, a palatine muscle,
and two throat muscles. The trigeminal
2. The oculomotor nerve (III) nerve has the greatest cutaneous
innervates four of six extrinsic eye sensory distribution of any cranial nerve.
muscles and the upper eyelid. The Two of the three trigeminal nerve
oculomotor nerve also provides branches innervate the teeth.
parasympathetic supply to the iris
and lens of the eye. 5. The abducens nerve (VI) controls one
of the extrinsic eye muscles.
3. The trochlear nerve (IV) controls
one of the extrinsic eye muscles
CHARACTERISTICS OF CRANIAL NERVES
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6. The facial nerve (VII) supplies the 8. The glossopharyngeal nerve (IX) is
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muscles of facial expression, an inner involved in taste and supplies tactile
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ear muscle, and two throat muscles. It sensory innervation from the posterior
is involved in the sense of taste. It is tongue, middle ear, and pharynx. It is
parasympathetic to two sets of also sensory for receptors that monitor
salivary glands and to the lacrimal blood pressure and gas levels in the
glands. blood. The glossopharyngeal nerve is
parasympathetic to the parotid salivary
7. The vestibulocochlear nerve (VIII) is glands.
involved in the senses of hearing and
balance.
CHARACTERISTICS OF CRANIAL NERVES
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9. The vagus nerve (X) innervates the 10. The accessory nerve (XI) has only a
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muscles of the pharynx, palate, and spinal component. It supplies the
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larynx. It is also involved in the sense sternocleidomastoid and trapezius
of taste. The vagus nerve is sensory muscles.
for the pharynx and larynx and for
receptors that monitor blood 11.The hypoglossal nerve (XII) supplies
pressure and gas levels in the blood. the intrinsic tongue muscles, three of
The vagus nerve is sensory for four extrinsic tongue muscles, and two
thoracic and abdominal organs. The throat muscles.
vagus nerve provides
parasympathetic innervation to the
thoracic and abdominal organs
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SUPPLEMENTAL LINKS
CNS: HTTPS://YOUTU.BE/Q8NTMDRB_QO
PNS: HTTPS://YOUTU.BE/QY9NTVH-AWO
SNS: HTTPS://YOUTU.BE/0IDGBLCHVSA
PSNS: HTTPS://YOUTU.BE/QQU-VJQJCZE
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RECAP OF
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TODAY'S MODULE
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RECAP 03 RECAP 04