Selecting An Airborne Particle Counter
Selecting An Airborne Particle Counter
Understanding which features you need in a particle can meet the ISO specifications in less time. A
counter is a difficult task. This article will identify the particle counter with a flow rate of 50 LPM can
various features available and help you choose sample one cubic meter in
which are relevant to your application. The right only 20 minutes.
particle counter will depend on the monitoring The ISO standards prescribe
environment, communications, monitoring purposes, limits for contamination and
desired flow rate, and particle size you choose to the limits can be converted
monitor. Pharmaceutical manufacturing has special to the obsolete Federal
monitoring requirements that are not completely Standard 209E (FS-209E).
addressed here. In most cases the ISO limits
Selecting an airborne-particle counter requires some are available for common
basic understanding of the terminology and particle sizes such as 0.1,
procedures. All airborne particle counters sample air 0.3, and 0.5 µm.
at specified volumetric flow rates, which are Figure 1. Lasair® III 350L
measured in cubic-feet-per-minute (CFM) or liters-
per-minute (LPM). Since particle counters are
calibrated at a specific flow rate, the sizing accuracy
is dependent upon that flow rate. Cleanroom ISO Certification
To meet most contamination specifications, particle When the primary application is cleanroom
counters must sample defined volumes of air; this certification, an instrument that has ISO certification
provides confidence in the particle data and is often features simplifies the process. The particle testing
stated as statistical significance. The ISO standard method must be accurate, reliable, and repeatable.
(ISO 14644) refers to cubic meters; to meet this Modern cleanrooms consistently meet ISO Class 5 or
standard, a 1 CFM particle counter must sample for Class 6 (FS-209E Class 100 or 1000). These
35 minutes (1 cubic foot multiplied by 35 equals 1 cleanroom classifications require the following limits:
cubic meter). Particle counters with faster flow rates
Monitoring a cleanroom in accordance with ISO counter maximum concentration value of greater than
cleanroom classifications requires the particle 10,200 particles per cubic meter (290 per cubic foot).
counter’s specification for maximum concentration to These are easily achieved limits with most modern
exceed ISO limits. For example, to monitor a Class 5 particle counters. Note that there is no ISO
cleanroom for 0.1 µm particles, the maximum specification for 0.1 µm particle counts higher than
concentration of the counter must be greater than ISO Class 6, so a 0.1 µm particle counter is not
100,000 particles per cubic meter (2,841 particles per required for those applications.
cubic foot). Using a 0.3 µm particle counter to monitor
the same Class 5 cleanroom requires a particle
Page | 1
Continuous or Frequent Cleanroom quantities of data that can overwhelm a system.
Monitoring Typical time intervals range from one minute to ten
minutes. Particle counter choices for these
Continuous or frequent monitoring in the cleanroom
applications are diverse and plentiful. Factors to
still needs to demonstrate compliance to ISO.
consider are:
Frequent monitoring requires sampling at specified • Particle size
time intervals not exceeding 60 minutes during • Flow rate
operation. Manifold systems are the least expensive • Communication options
suitable solution and are best installed during the
If a cleanroom offers network ports (Ethernet’s
cleanroom construction process. Standalone particle
10Base-T or 100Base-T), select a particle counter
counters may be installed at any time. A manifold
with networking capability. If the cleanroom relies
system includes either 16 or 32 sampling ports with a
upon serial communications, select a particle counter
single line that connects to a particle counter. The
with RS-232 or RS-485 communication protocols.
manifold sequentially samples from each port, sends
the samples to the particle counter, and then repeats Choosing between continuous and frequent
the process. However, since a manifold cycles cleanroom monitoring is a choice of economics and
through many sample points, a particle event can go infrastructure. Dedicated particle counters are the
unnoticed if the particle counter is not currently best method to detect particle excursions, but at a
monitoring the appropriate port. high cost per sample point. If short-duration events
are not critical and the need is for trending, a manifold
Continuous monitoring requires constant sampling.
system can be an effective and economical solution.
This method constantly gathers data, so events are
However, manifold systems cannot reliably transport
not missed. Sample intervals can be any duration, but
and count particles much larger than 5 µm.
shorter sample intervals will give better time
resolution. Short time intervals will provide vast
Cleanroom Monitoring Solutions
Frequency Particle Size Flow Rate Communication Product
Frequent 0.1 µm 1.0 CFM 10Base-T Lasair II 110
with AM-II-16 or AM-II-32 Manifold
Continuous 0.2 µm 1.0 CFM 10Base-T Airnet®II 201
Continuous 0.3 µm 1.0 CFM 10Base-T Airnet II 310
Continuous 0.3 µm 0.1 CFM 10Base-T Airnet II 301
Continuous 0.5 µm 1.0 CFM 10Base-T Airnet II 510
Continuous 0.3 µm 0.1 CFM RS-485 RNet® 301
Continuous 0.5 µm 1.0 CFM RS-485 RNet 510
Minienvironment particle data often follows trends in since the cost of a particle counter doubles as the
differential air pressure, so an instrument’s ability to sensitivity increases from 0.3 µm to 0.1 µm, the most
correlate particle and differential pressure data cost-effective continuous monitoring solution is a
provides trend analysis, yield improvements, and 0.3 µm particle counter with an inclusive differential
accurately scheduled preventative maintenance air pressure (DAP) probe. For validation and
cycles. certification, a 0.1 µm counter is recommended for
ISO Class 1 and ISO Class 2 minienvironments.
Published minienvironment particle data1 shows
particle concentrations clustered near 0.4 µm, and
Lab Testing tested in the lab, so the lab must define the critical
particle size limit (in µm) and the acceptable
Lab testing applications do not typically need to meet
maximum concentration limits.
ISO cleanroom requirements. These applications
seek a specific number of particle counts within a High flow rates are often desirable as they increase
certain size range, and this number defines whether throughput, reduce sampling times, and gather more
the lab components will pass or fail. Particle counter data. Since lab tests tend to focus upon sub-
selection is dependent on the components being micrometer contamination, the choices narrow for
particle counters.
Page | 3
Lab Testing Solutions
Product Particle Size Flow Rate
LASAIR II 110 0.1 µm 1.0 CFM
LASAIR III 310C 0.3 µm 1.0 CFM
LASAIR III 350L 0.3 µm 1.78 CFM
LASAIR III 5100 0.5 µm 3.56 CFM
Harsh Environments
Harsh environments require special instrumentation. LASAIR III 5100, Airnet II series, IsoAir series, and
These environments may include pharmaceutical labs, RNet provide this functionality. If a pharmaceutical lab
cleanroom make-up air handling (MUAH) units, fan contains heavy concentrations of hydrogen peroxide
decks, or aerospace launch facilities. These (H2O2), a particle counter with resilient coating and
conditions require particle counters that are isolated high maximum sampling concentrations, such as the
from the environment but still provide accurate air Airnet II 510 XR, is recommended.
sampling. MUAHs, fan decks, and launch systems require
Particle counters developed for harsh environments robust enclosures that can withstand conditions
are often housed in NEMA-rated enclosures. These outside normal room environments. Appropriate
enclosures isolate the sensitive optics and electronics, particle counters for this use have enclosures made
while providing an external probe for monitoring the from stainless steel or Kydex®, which provide superior
particle concentrations. resistance to damaging external conditions, but have
proven reliability in particle counting. Some of the
Pharmaceutical manufacturers’ interests lie only in instruments that meet these conditions include the
0.5 µm and 5.0 µm. Some particle counters offer IsoAir and IsoAir 310P, the Airnet II series, and the
screen/data configurations that only display/print RNet.
these specific channels. The LASAIR III 350L and
Product Particle Size Pressure Range Purpose Gas Type Flow Rate
HPGP-101-C 0.1 µm 40-150 psig Dedicated Sampling Reactive 0.1 CFM
MLPC-101-HP 0.1 µm 40-150 psig Dedicated Sampling Non-Reactive 0.1 CFM
LASAIR II 110 Dedicated, Occasional, or
0.1 µm 40-100 psig Non-Reactive 1.0 CFM
with HPD II-100 Periodic Testing
LASAIR III 310C Dedicated, Occasional, or
0.3 µm 25-100 psig Non-Reactive 1.0 CFM
with HPD III Periodic Testing
Conclusion
While the purchasing choices may seem endless,
evaluating your particular application will help you
focus on your requirements. Using the basic
guidelines provided in this article will help you
purchase the ideal counter to meet your requirements
without paying for features you do not need.
References
1. High-yield manufacturing: Particle Monitoring in Minienvironments; CleanRooms Magazine, April 2004
Page | 5