Side Effects of Antipsychotic Medications (PS CAT DOG)
Side Effects of Antipsychotic Medications (PS CAT DOG)
P - Photosensitivity
o X direct sunlight
o Use sunglasses, SPF 25, umbrella
S - Sedation
o Caution in driving
C - Constipation
o Cholinergic effect (SNS)
o Increase OFI
o Increase fiber diet
A - Agranulocytosis
o Decreased WBCs → Risk for Infection
o WOF this in patients taking Clozapine
o Instruct patient to report of fever and sore throat (S/Sx of infection)
T - Tooth decay
D - Dry mouth
o Cholinergic effect (SNS)
o Give sugarless gum, hard candy to stimulate anticholinergic effects
O - Orthostatic hypotension
o Dangle feet before arising from bed
o Change positions gradually
G - Galactorrhea
o Milk discharge from patients
o Use cotton underwear
EPS (Extrapyramidal syndrome)
o Cause decreased dopamine due to antipsychotics given
o 3 components (DAP)
D - Dystonia (DOT)
D - Dysphagia (difficulty swallowing), drooling
O - Oculogyric crisis (Upward deviation of eye)
T - Torticollis (Stiff neck)
Tx (ABC)
o Akineton (Biperiden)
o Benadryl (Diphenhydramine)
o Cogentin (Benztropine)
A - Akathisia
o Restlessness, inability to sit still
o Tx: Propranolol (Beta-Blocker)
P - Pseudoparkinsonism
o Resting tremors, unstable gait
o Tx: Pramipexole (Mirapex), Amantadine
(Symmetrel)
What would be the immediate nursing action if the
patient is experiencing dysphagia, torticollis and tremors?
Notify MD.
o X discontinue → relapse of S/Sx
Other management. Lower the dose/shift to another med
Prevention: Early detection (notify MD immediately)
Neuroleptic malignant syndrome
o Muscle spasms + fever
o Muscle spasms → laryngospasms → airway obstruction
o Most fatal SE of antipsychotic medications
o Immediate nursing action: discontinue immediately
o Management: muscle relaxants
o Prevention: hydration
Tardive dyskinesia
o Last SE to occur - would only occur after 6 months
o permanent, irreversible
o s/sx: tongue protrusion and twisting, teeth grinding and lip smacking
o Immediate nurse action: notify MD
o Tx: valbenazine (Ingressa)