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An Easy Guide to Neuron Anatomy

with Diagrams
Medically reviewed by Nancy Hammond, M.D. — By Carly Vandergriendt and Rachael
Zimlich, RN, BSN — Updated on February 28, 2022

Anatomy Types Function Research Takeaway

Neurons, also known as nerve cells, send and receive

signals from your brain. While neurons have a lot in
common with other types of cells, they’re structurally and
functionally unique.

Neurons, also known as nerve cells, send and receive signals from your brain. While
neurons have a lot in common with other types of cells, they’re structurally and functionally
unique.

Specialized projections called axons allow neurons to transmit electrical and chemical
signals to other cells. Neurons can also receive these signals via rootlike extensions known
as dendrites.

A 2009 study estimated that the human brain houses about 86 billion neurons  . The
creation of new nerve cells is called neurogenesis. While this process isn’t well understood,
we know that it’s much more active when you’re an embryo. However, 2013 evidence 
suggests that some neurogenesis occurs in adult brains throughout our lives.

As researchers gain insight into both neurons and neurogenesis, many are also working to
uncover links to neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

Illustration by Sophia Smith

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Parts of a neuron
Neurons vary in size, shape, and structure depending on their role and location. However,
nearly all neurons have three essential parts: a cell body, an axon, and dendrites.

Cell body
Also known as a soma, the cell body is the core section of the neuron. The cell body
contains genetic information, maintains the neuron’s structure, and provides energy to drive
activities.

Like other cell bodies, a neuron’s soma contains a nucleus and specialized organelles. It’s
enclosed by a membrane that both protects it and allows it to interact with its immediate
surroundings.

Axon
An axon is a long, tail-like structure. It joins the cell body at a specialized junction called the
axon hillock. Many axons are insulated with a fatty substance called myelin. Myelin helps
axons to conduct an electrical signal.

Neurons usually have one main axon.

Dendrites
Dendrites are fibrous roots that branch out from the cell body. Like antennae, dendrites
receive and process signals from the axons of other neurons. Neurons can have more than
one set of dendrites, known as dendritic trees.

How many they have generally depends on their role. For instance, Purkinje cells are a
special type of neuron found in a part of the brain called the cerebellum. These cells have
highly developed dendritic trees which allow them to receive thousands of signals.

Illustration by Sophia Smith

Types of neurons
Neurons vary in structure, function, and genetic makeup. Given the sheer number of
neurons, there are thousands of different types, much like there are thousands of species of
living organisms on Earth.

However, there are five major neuron forms. Each combines several elements of the basic
neuron shape.

Multipolar neurons. These neurons have a single axon and symmetrical dendrites that
extend from it. This is the most common form of neuron in the central nervous system.
Unipolar neurons. Usually only found in invertebrate species, these neurons have a
single axon.
Bipolar neurons. Bipolar neurons have two extensions extending from the cell body.
At the end of one side is the axon, and the dendrites are on the other side. These
types of neurons are mostly found in the retina of the eye. But they can also be found
in parts of the nervous system that help the nose and ear function.
Pyramidal neurons. These neurons have one axon but several dendrites to form a
pyramid type shape. These are the largest neuron cells and are mostly found in the
cortex. The cortex is the part of the brain responsible for conscious thoughts.
Purkinje neurons. Purkinje neurons have multiple dendrites that fan out from the cell
body. These neurons are inhibitory neurons, meaning they release neurotransmitters
that keep other neurons from firing.

In terms of function, scientists classify neurons into three broad types: sensory, motor, and
interneurons.

Sensory neurons
Sensory neurons help you:

taste
smell
hear
see
feel things around you

Sensory neurons are triggered by physical and chemical inputs from your environment.
Sound, touch, heat, and light are physical inputs. Smell and taste are chemical inputs.

For example, stepping on hot sand activates sensory neurons in the soles of your feet.
Those neurons send a message to your brain, which makes you aware of the heat.

Motor neurons
Motor neurons play a role in movement, including voluntary and involuntary movements.
These neurons allow the brain and spinal cord to communicate with muscles, organs, and
glands all over the body.

There are two types of motor neurons: lower and upper. Lower motor neurons carry signals
from the spinal cord to the smooth muscles and skeletal muscles. Upper motor neurons
carry signals between your brain and spinal cord.

When you eat, for instance, lower motor neurons in your spinal cord send signals to the
smooth muscles in your esophagus, stomach, and intestines. These muscles contract, which
allows food to move through your digestive tract.

Interneurons
Interneurons are neural intermediaries found in your brain and spinal cord. They’re the most
common type of neuron. They pass signals from sensory neurons and other interneurons to
motor neurons and other interneurons. Often, they form complex circuits that help you to
react to external stimuli.

For instance, when you touch something sharp like a cactus, sensory neurons in your
fingertips send a signal to interneurons in your spinal cord. Some interneurons pass the
signal on to motor neurons in your hand, which allows you to move your hand away. Other
interneurons send a signal to the pain center in your brain, and you experience pain.

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How do neurons work?

Neurons send signals using action potentials. An action potential is a shift in the neuron’s
potential electric energy caused by the flow of charged particles in and out of the
membrane of the neuron. When an action potential is generated, it’s carried along the axon
to a presynaptic ending.

Action potentials can trigger both chemical and electrical synapses. Synapses are locations
where neurons can pass these electrical and chemical messages between them. Synapses
are made up of a presynaptic ending, a synaptic cleft, and a postsynaptic ending.

Chemical synapses
In a chemical synapse, the neuron releases of chemical messengers called
neurotransmitters. These molecules cross the synaptic cleft and bind to receptors in the
postsynaptic ending of a dendrite.

Neurotransmitters can trigger a response in the postsynaptic neuron, causing it to generate

an action potential of its own. Alternatively, they can prevent activity in the postsynaptic
neuron. In that case, the postsynaptic neuron doesn’t generate an action potential.

Electrical synapses
Electrical synapses can only excite. These synapses form when two neurons are connected
by a gap junction. This gap is much smaller than a chemical synapse and is made up of ion
channels that help transmit a positive electrical signal.

Because of the way these signals travel, signals move much faster across electrical
synapses than chemical synapses. However, these signals can diminish from one neuron to
the next. This makes them less effective at transmitting repeated signals.

Recent research
While research has advanced our understanding of neurons in the last century, there’s still
much we don’t understand.

For instance, until recently, researchers believed that neuron creation occurred in adults in
a region of the brain called the hippocampus. The hippocampus is involved in memory and
learning.

But a 2018 study  found that the production of neurons in the hippocampus actually drops
after birth. This means that virtually no new neurons are created there by adulthood.

Experts considered this discovery a setback in terms of using neurogenesis to treat

diseases like Alzheimer’s and Parkinson’s. These conditions are both the result of neuron
damage and death.

There is still hope, though, that neural stem cells can be used to make new neurons. Neural
stem cells can produce new neurons, according to the National Institute of Neurological
Disorders and Stroke  . But researchers are still trying to figure out the best way to use
these stem cells to produce specific types of neurons in the laboratory setting.

If this can be done, these nerve cells could be created to replace those that are lost through
age, damage, and disease.

Ongoing clinical trials

Many clinical trials are currently underway to test the use of newly created neural cells. For
example, this one targets people who have had an ischemic stroke.

Also, a 2019 study  used fluorescent probes to observe real-time activity in the nerve cells
of mice. This technology could be used to help map brain activity, uncover the problems
that lead to neurological disorders, and advance the field of artificial intelligence.

Educational resources
Want to see how much you learned today? Use the resources below to quiz yourself
(or your students) on the anatomy and different types of neurons.

Anatomy of a Neuron study guide

Anatomy of a Neuron quiz
Types of Neurons study guide
Types of Neurons quiz

Quiz yourself on the anatomy of a neuron!

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Takeaway
Nervous system cells are called neurons. They have three distinct parts, including a cell
body, axon, and dendrites. These parts help them to send and receive chemical and
electrical signals.

While there are billions of neurons and thousands of varieties of neurons, they can be
classified into three basic groups based on function. These are motor neurons, sensory
neurons, and interneurons.

There’s still a lot we don’t know about neurons and the role they play in the development of
certain brain conditions. But many research projects and clinical trials are underway to try
and find those answers.

Last medically reviewed on February 28, 2022

How we reviewed this article:

SOURCES HISTORY

Our experts continually monitor the health and wellness space, and we update our articles
when new information becomes available.

Current Version

Feb 28, 2022

Medically Reviewed By
Nancy Hammond, MD

Jul 20, 2018

Written By
Carly Vandergriendt, Rachael Zimlich

Edited By
Rayne Whitington

Medically Reviewed By
Seunggu Han, MD

Copy Edited By
Emily Schalk

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