Module 2 ILT1 Statistics in Analytical Chemistry
Module 2 ILT1 Statistics in Analytical Chemistry
use existing knowledge or theories to make predictions about what will happen before you
make an observation
a new or unusual observation is made when that observation doesn’t fit the current knowledge
or theories
propose an explanation for this new or unusual observation (this explanation could simply be
“we observed it wrong”)
test the explanation through controlled experimentation
do not make firm conclusions until they have be verified through replication (preferably by
independent researchers)
once verified, update the current knowledge or theories to incorporate these new or unusual
observations
II. Statistics and Science
Many experiments deal with complex or difficult to measure phenomena. Equally these
experiments use sample data and seek to generalize the results beyond the observations made with
the sample data. As such, determining what a sample set of observations tells us about a proposed
explanation in general requires us to make an inference, or as we statisticians call it, to “Reason With
Uncertainty”. Reasoning with uncertainty is the core of statistical inference and is typically done using
a method called Null Hypothesis Significance Testing (NHST). NHST, in essence, follows these
steps:
1. State what you expect to happen if we assume nothing has changed
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2. Select the amount evidence required to be obtained in order to reject that assumption (i.e. that
nothing has changed)
3. Using the sample data and an appropriate statistical technique, compute a decision statistic
4. If the decision statistic provides enough evidence, then we reject the assumption that nothing
has changed and conclude that we have a set of sample data that suggests that something
has changed
It is important to recognize that when conducting NHST that it is not a proof or definitive
statement that something or nothing has changed, but rather that it lends weight to one conclusion or
the other. As such, replication IS required in order to make a firm conclusion. From the above
descriptions, you should be able to see that Statistics and the “Scientific Method” are rather similar.
This should not be surprising since statistics itself is a science, the science of uncertainty, and
therefore follows good scientific principles.
III. Task. Terms used in Statistics
Research and provide definition of the following terms used in performing Statistical
computations. Provide a reference list of your sources of answers.
4. Inferential Statistics Inferential statistics are tools that statisticians use to draw
conclusions about the characteristics of a population,
drawn from the characteristics of a sample, and to decide
how certain they can be of the reliability of those
conclusions. Based on the sample size and distribution
statisticians can calculate the probability that statistics,
which measure the central tendency, variability,
distribution, and relationships between characteristics
within a data sample, provide an accurate picture of the
corresponding parameters of the whole population from
which the sample is drawn.
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a conclusion about the parameter.
16. Constant Factors A quantity which can assume only one value.
17. Control Group A control group is a statistically significant portion of
participants in an experiment that are shielded from
exposure to variables.
18. Experimental Group An experimental group is a test sample or the group that
receives an experimental procedure. This group is
exposed to changes in the independent variable being
tested. The values of the independent variable and the
impact on the dependent variable are recorded. An
experiment may include multiple experimental groups at
one time.
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19. Mean The mean (average) of a data set is found by adding all
numbers in the data set and then dividing by the number
of values in the set.
20. Median The median is the middle value when a data set is
ordered from least to greatest.
21. Mode The mode is the number that occurs most often in a data
set.
22. Standard Deviation Defined as a number representing how far from the
average each score is.
23. Variance Defined as a number indicating how spread out the data
is.
25. Confidence Level Confidence level is the percentage of times you expect to
reproduce an estimate between the upper and lower
bounds of the confidence interval, and is set by the alpha
value.
26. Decision Criterion A criterion is set upon which a researcher will decide
whether to retain or reject the value stated in the null
hypothesis.
27. Null Hypothesis Null hypothesis is a type of statistical hypothesis that
proposes that no statistical significance exists in a set of
given observations. Hypothesis testing is used to assess
the credibility of a hypothesis by using sample data.
Sometimes referred to simply as the "null," it is
represented as H0.
29. Statistical Error Error (statistical error) describes the difference between a
value obtained from a data collection process and the
'true' value for the population. The greater the error, the
less representative the data are of the population.
31. Test of Difference The test of significance showed that the difference
between the sample mean and the population mean is
statistically significant. A two-sided alternative hypothesis
is used when there is no reason to believe that the
sample mean can only be higher or lower than a given
value.
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32. Post Hoc Analysis Post hoc (Latin, meaning “after this”) means to analyze
the results of your experimental data. They are often
based on a familywise error rate; the probability of at least
one Type I error in a set (family) of comparisons.
References
1. Ovens, M.2018. “Statistics and the “Scientific Method”” Retrieved
from https://www.yourstatsguru.com/secrets/scimethod-stats/
Your References Below
5. CFI TEAM, (2022) ParameterCharacteristics that are used to define a given population.
https://corporatefinanceinstitute.com/resources/knowledge/other/parameter/ .
6 . Stephanie Glen. "What is a Population in Statistics?" From StatisticsHowTo.com: Elementary
Statistics for the rest of us! https://www.statisticshowto.com/what-is-a-population/
7. WILL KENTON, (2022) Sample.
https://www.investopedia.com/terms/s/sample.asp
8. https://www.texasgateway.org/resource/11-definitions-statistics-probability-and-key-
terms#:~:text=Data%20are%20the%20actual%20values,statistics%20are%20mean%20and
%20proportion.
9. https://www.texasgateway.org/resource/11-definitions-statistics-probability-and-key-
terms#:~:text=Data%20are%20the%20actual%20values,statistics%20are%20mean%20and
%20proportion.
10. Johnson, (2021) Qualitative and Quantitative Variable in Statistics
https://study.com/learn/lesson/qualitative-quantitative-variables-in-statistics.html
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13. Hayes, A.F. (2013) Introduction to Mediation, Moderation, and Conditional Process Analysis: A
Regression-Based Approach. New York, NY: Guilford Press.
https://www.statisticshowto.com/moderating-variable/
16. https://www.emathzone.com/tutorials/basic-statistics/some-basic-definitions-in-statistics.html
17. KC Karnes, (2020) What is a Control Group and Why is it Important in Testing?
https://clevertap.com/blog/what-is-a-control-group/#:~:text=A%20control%20group%20is%20a,no
%20effect%20on%20the%20body.
18. Todd Helmenstine, (2020). The Difference Between Control Group and Experimental Group,
https://www.thoughtco.com/control-and-experimental-group-differences-606113
19. Sal Khan, (2012) Statistics intro: Mean, median, & mode. https://www.khanacademy.org/math/cc-
sixth-grade-math/cc-6th-data-statistics/mean-and-median/v/statistics-intro-mean-median-and-
mode#:~:text=The%20mean%20(average)%20of%20a,often%20in%20a%20data%20set.
20. Sal Khan, (2012) Statistics intro: Mean, median, & mode. https://www.khanacademy.org/math/cc-
sixth-grade-math/cc-6th-data-statistics/mean-and-median/v/statistics-intro-mean-median-and-
mode#:~:text=The%20mean%20(average)%20of%20a,often%20in%20a%20data%20set.
21. Sal Khan, (2012) Statistics intro: Mean, median, & mode. https://www.khanacademy.org/math/cc-
sixth-grade-math/cc-6th-data-statistics/mean-and-median/v/statistics-intro-mean-median-and-
mode#:~:text=The%20mean%20(average)%20of%20a,often%20in%20a%20data%20set.
22. Devin Kowalczyk, (2003-2022), Measures of Variability: Range, Variance & Standard Deviation.
https://study.com/academy/lesson/measures-of-variability-range-variance-standard-deviation.html.
23. Devin Kowalczyk, (2003-2022), Measures of Variability: Range, Variance & Standard Deviation.
https://study.com/academy/lesson/measures-of-variability-range-variance-standard-deviation.html
24. Devin Kowalczyk, (2003-2022), Measures of Variability: Range, Variance & Standard Deviation.
https://study.com/academy/lesson/measures-of-variability-range-variance-standard-deviation.html
25. Rebecca Bevans, (2020), Understanding Confidence Intervals | Easy Examples & Formulas.
https://www.scribbr.com/statistics/confidence-interval/#:~:text=a%20confidence%20level%3F-,The
%20confidence%20level%20is%20the%20percentage%20of%20times%20you%20expect,a
%20given%20level%20of%20confidence.
26. https://www.sagepub.com/sites/default/files/upm-binaries/40007_Chapter8.pdf
27.ADAMHAYES, (2022), Null Hypothesis
https://www.investopedia.com/terms/n/null_hypothesis.asp
28. Jim Frost,(2020) Alternative hypothesis, https://statisticsbyjim.com/jim_frost/.
29.https://www.google.com/search?
q=statistical+error+in+statistics&oq=Statistical+Error+in+&aqs=chrome.2.0i512j69i57j0i512l3j0i22i30l
3j0i15i22i30j0i22i30.5903j0j4&sourceid=chrome&ie=UTF-8
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32. Levine, D. (2014). Even You Can Learn Statistics and Analytics: An Easy to Understand Guide to
Statistics and Analytics 3rd Edition. Pearson FT Press. https://www.statisticshowto.com/probability-and-
statistics/statistics-definitions/post-hoc/
*Please edit the number of pages as you write your answers this lesson
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