Scribd
Upload
21 views

Manganese Assignment - Removed

Manganese is a trace element that plays important roles as a cofactor for enzymes involved in metabolism of carbohydrates, lipids, and amino acids. It is essential for bone health, reproduction, wound healing, and neurological functions. Good dietary sources of manganese include nuts, whole grains, legumes, fruits, and vegetables.

Uploaded by

bhavya
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
21 views

Manganese Assignment - Removed

Manganese is a trace element that plays important roles as a cofactor for enzymes involved in metabolism of carbohydrates, lipids, and amino acids. It is essential for bone health, reproduction, wound healing, and neurological functions. Good dietary sources of manganese include nuts, whole grains, legumes, fruits, and vegetables.

Uploaded by

bhavya
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 5

ROLE

OF
MANGANESE

Name: G.Bhavya bharathi


Reg no: 722210304008
Class: Msc 1 st yearbiotechnology
ROLE OF MANGANESE[Mn] IN HUMAN BODY:
INTRODUCTION:
 Manganese is a naturally occurring transition metal and important
trace element in the body.
 Manganese chemical symbol is Mn and the atomic number is 25.
 In the body, manganese is a cofactor of many important enzymes
that are involved in the synthesis of polysaccharide, fatty acids,
and urea from ammonia, regeneration of red blood cells, the
reproductive cycle, and chondroitin synthesis in bone matrix
 Despite several health benefits, excessive exposure to manganese
in an extended period of time can lead to manganese induced
neurotoxicity, which can present as physical and/or psychological
disorders
Discovery:
 Manganese was first discovered by 1774 by chemist Carl Scheele.
 In 1970 the first case of manganese deficiency was recorded.

Fig:1 Manganese element Fig:2 Sir Carl scheele


Sources:
 Many foods contain manganese, and it is an essential nutrient
in our diet. Good dietary sources of manganese include:
 Nuts and seeds : Almond,hazelnut
 Whole grains: brown rice , oats
 Legumes: chickpeas
 Fruits:Pineapple, raspberry
 Vegetable : spinach, sweet potato

Fig3:Manganese foods chart


Role of manganese in human body :
1) Enzyme Activation:
 Manganese acts as a cofactor for many enzymes involved
in various metabolic pathways.
 It participates in the activation of enzymes that play roles
in amino acid, lipid, and carbohydrate metabolism.
 For example, manganese is essential for the proper
function of enzymes involved in the synthesis of
cholesterol, glucose metabolism, and the breakdown of
amino acids.
2) Bone Health:
 Manganese is essential for the synthesis of connective
tissues, including cartilage and bone.
 It aids in the formation of bone matrix and the proper
development and maintenance of healthy bones
 It contributes to the synthesis of connective tissues and
helps in the production of the structural components of
bones.
3. Metabolism:
 Manganese plays a role in various metabolic processes,
including the metabolism of amino acids, carbohydrates,
and cholesterol.
 Manganese plays a role in gluconeogenesis, a process by
which the body produces glucose from non-carbohydrate
sources, such as amino acids and glycerol.
4. Neurotransmitter Production:
 Manganese is involved in the synthesis of certain
neurotransmitters, such as serotonin and norepinephrine,
which are essential for mood regulation and overall brain
function.
5. Blood Sugar Regulation:
 Manganese is thought to be involved in maintaining
normal blood sugar levels by participating in the
metabolism of glucose.
6. Wound Healing:
 Manganese aids in the formation of blood clots and
contributes to the wound healing process.
 Manganese is required for the activation of prolidase,
an enzyme that functions to provide the amino acid,
proline, for collagen formation in human skin cells
7. Reproduction:
 Manganese is important for normal reproductive function
and fetal development during pregnancy.
 However, manganese toxicity is rare and typically occurs
with long-term exposure to high levels of manganese, such
as in certain occupational settings.
 The recommended dietary intake of manganese for adults
is typically around 2.3 mg per day for men and 1.8 mg per
day for women.
Manganese deficiency and toxicity:

Deficiency Adequacy Toxicity

 Cardio- Normal bone  Central


Vascular:Reduced formation and Nervous
blood cholesterol amino acid, system:effects
levels cholesterol, and parkinson’s
 Central Nervous carbohydrate disease
System: altered Metabolism.  Neuro –
moodand Muscular:
increased pain (in Rigidity of limbs,
reproductively lack of coordination.
capable Women)

You might also like