8

Science
Quarter 4 – Module 3: The
Significance of Meiosis

CO_Q4_Science 8_ Module 3
Science – Grade 8
Alternative Delivery Mode
Quarter 4 – Module 3: The Significance of Meiosis
First Edition, 2020

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Published by the Department of Education

Secretary: Leonor Magtolis Briones
Undersecretary: Diosdado M. San Antonio

Development Team of the Module

Writer: Marilou C. Salazar
Editor: Melvyn C.Montes
Reviewers: Bernabe L. Linog, Corazon P. Roa, Juvy B. Luna, Arlene L. Abala,
Kathyleen S. Torculas and Nonita C. Patalinghug
Illustrators: Marilou C. Salazar and Rosa Mia L. Pontillo
Layout Artist: Edgardo D. Pamugas III
Layout Evaluators: Celeste Faith R. Almanon and Jay S. Ayap
Management Team: Francis Cesar B.Bringas
Isidro M. Biol, Jr.
Maripaz F. Magno
Josephine Chonie M. Obseñares
Gregoria T. Su
Marvilyn C. Francia
Jay S. Ayap
Nonita C. Patalinghug

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J. P. Rosales Avenue, Butuan City, Philippines 8600
Telefax: (085) 342-8207/ (085)342-5969
E-mailAddress: [email protected]
 8

Science
Quarter 4 – Module 3: The
Significance of Meiosis
Introductory Message
This Self-Learning Module (SLM) is prepared so that you, our dear learners,
can continue your studies and learn while at home. Activities, questions, directions,
exercises, and discussions are carefully stated for you to understand each lesson.

Each SLM is composed of different parts. Each part shall guide you step-by-
step as you discover and understand the lesson prepared for you.

Pre-tests are provided to measure your prior knowledge on lessons in each

SLM. This will tell you if you need to proceed on completing this module or if you
need to ask your facilitator or your teacher’s assistance for better understanding of
the lesson. At the end of each module, you need to answer the post-test to self-
check your learning. Answer keys are provided for each activity and test. We trust
that you will be honest in usingthese.

In addition to the material in the main text, Notes to the Teacher are also
providedtoourfacilitatorsandparentsforstrategiesandremindersonhowtheycan best
help you on your home-basedlearning.

Please use this module with care. Do not put unnecessary marks on any part
of this SLM. Use a separate sheet of paper in answering the exercises and tests.
And read the instructions carefully before performing each task.

If you have any questions in using this SLM or any difficulty in answering the
tasks in this module, do not hesitate to consult your teacher or facilitator.

Thank you.
 What I Need to Know

This module was designed and written with you in mind. It is here to help you
master the significance of meiosis. The scope of this module permits it to be used
in many different learning situations. The language used recognizes the diverse
vocabulary level of students. The lessons are arranged to follow the standard
sequence of the course. But the order in which you read them can be changed to
correspond with the learner’s material you are now using.

This module contains:

 Lesson 1 – The Significance ofMeiosis

After going through this module, you are expected to:

1. explaingametogenesis;
2. explain the role of meiosis ingametogenesis;
3. describe the abnormalities that may occur during meiosis;and
4. explain the significance of meiosis in maintaining the
chromosome number of an organism. (MELC Week 2S8LT-IVe-17)

1 CO_Q4_Science 8_ Module 3
 What I Know

Directions:Choose the letter of the correct answer. Write your answers on a separate
sheet of paper.

1. Gametogenesis is theformationof .
A. bodycells
B. gonads
C. sexcells
D. somaticcells
2. Which statement describesgametogenesis?
A. It produces haploidcells.
B. It takes place in plantsalone.
C. It does not occur inmammals.
D. It always starts with haploidcells.

3. Which is true about spermatogenesis?Each primary spermatocyte produces

.
A. four diploidspermatids
B. four haploidspermatids
C. one diploid spermatid; four polarbodies
D. one haploid spermatid; four polarbodies

4. After a complicated process of differentiation or transformation, the

spermatids become .
A. primaryspermatocytes
B. secondaryspermatocytes
C. spermatogonia
D. sperms
5. Which part of the sperms has thegenetic information?
A. acrosome
B. head
C. middlepiece
D. tail

6. Which are produced during meiosis in thetestes?

A. 4 diploidsperms
B. 4 haploidsperms
C. 23 diploidsperms
D. 23 haploidsperms
7. Whichofthefollowingisproducedduringmeiosisintheovary?
A. 1 diploidovum
B. 1 haploidovum
C. 4 haploidova
D. 23 diploidova

2 CO_Q4_Science 8_ Module 3
8. In oogenesis, which one produces thefirst polar body?
A. oogonia
B. primaryoocyte
C. secondaryoocyte
D. primordial germcell

9. Which statement is FALSE aboutoogenesis?

A. Production of haploidovum.
B. Degeneration of polarbodies.
C. Production of haploid primaryoocyte.
D. Production of haploid secondaryoocyte.

10. What processes are involved ingametogenesis?

A. meiosis I andII
B. mitosis andmeiosis
C. mitosis and meiosisI
D. mitosis and meiosisII
11. Which causes Downsyndrome?
A. viralinfection
B. bacterialinfection
C. chromosomalabnormality
D. lackofoxygensupplytothebrainatbirth
12. ThefollowingarethecharacteristicsofapersonwithPatausyndromeEXCEPT:
A. cleftlip
B. extrafingers
C. Simiancrease
D. smallstature

13. A child with Klinefelter syndrome has how manychromosomes?

A. 44
B. 45
C. 46
D. 47

14. The other name for Cri-du-Chatsyndromeis .

A. Trisomy13
B. Trisomy21
C. 47, XXYsyndrome
D. “Cat cry”syndrome

15. Which is themain role of meiosis in gametogenesis?

A. for growth of bodycells
B. for asexualreproduction
C. for cell repair andreplacement
D. for reduction of chromosome number of gametes

3 CO_Q4_Science 8_ Module 3
 Lesson

1 The Significance of Meiosis

What’s In
Directions:WriteTrueifthestatementiscorrectandFalseifthestatementis
wrong.Writeyouranswersonaseparatesheetofpaper.

1. Gametes are sexcells.

2. Each meiosis has fourphases.
3. Gametes have 22chromosomes.
4. The parent cell divides threetimes.
5. Meiosis1issimilarwithmeiosis2.
6. Sister chromatids are identicalchromosomes.
7. Prophase 1 is the longest phase duringmeiosis.
8. Meiosisisaprocessinwhichidenticalcellsareproduced.
9. Adiploidcellhastwicethequantityofgeneticinformation.
10. Gametesthroughmeiosisarewithsimilargenestotheirparents.

Meiosis is a type of cell division that takes place during the creation of sex
cells.Duringmeiosis,thechromosomenumberisdecreasedbyhalf.Thisistoensure that
the zygote would receive the exact number of chromosomes during fertilization.
Thecreation of germ cells or gametes is referred to as gametogenesis.
These gametes are used for sexualreproduction.

During gametogenesis, a cell which contains one set of every pair of

chromosome comes from a diploid cell (2N). Male and female individuals produce
their gametes through meiosis. In males, gametogenesis is known
as spermatogenesis. This process produces spermatozoa (singular form is
spermatozoon) or sperm cells. Gametogenesis in females is known as oogenesis,
since it produces oocytes and yields mature ova (singular form ovum) or egg cells.
Both processes begin with meiosis. The creation of sperm cells happens in the
testes while egg cell production happens inside the ovary. The formation of embryo
does not occur normally without the process ofmeiosis.

Meiosis functions for the proper conditioning of cells inside the gonads in
preparation for reproduction and for genetic diversity among organisms. But the
basic function of meiosis is to maintain the standard number of chromosomes of
the organism or species after the union of sex cells during fertilization. This is
possible
whenthedivisionandthereductionofchromosomenumberofgametesfromdiploid (2N)
to haploid (N)occurs.

4 CO_Q4_Science 8_ Module 3
 What’s New

Activity 1. What is the Number?

Directions: Study the diagram of gametogenesis where egg cells and sperm cells
undergomeiosisIandmeiosisII.Notethenumberassignedtoeachcell.
Identify the number of chromosomes in the different cells, represented
by a circle, by writing the symbol N for haploid and 2N for the diploid.
Write your answers on a separatesheet of paper.

Illustrated by: Marilou C. Salazar

What is It

Role of Meiosis in Gametogenesis

Multicellularorganismsareformedbytheunionofgametesorsexcells.These sex
cells, eggs and sperms are created through the process gametogenesis. For
gametogenesis to occur successfully, meiosis is required in reducing the number of
chromosomes of gametes from diploid (2N), having a complete set of
chromosomes, to haploid (N) where the gametes carry only half the standard
number of chromosomes. When these eggs and sperms unite during fertilization, a
diploid zygote forms. The zygote has one full set of chromosomes received from
each parent. Inhumans,boththefatherandthemothercontribute23chromosomeseach

5 CO_Q4_Science 8_ Module 3
through their sex cells. Thus, the zygote has 46 chromosomes. The zygote divides
through mitosis many times. This produces a new diploid multicellular organism.
Four haploid cells (N) are produced after meiosis. These cells undergo development
for them to become mature and functional gametes. The process of gametogenesis
differs between male and female organisms. This happens inside the gonads or the
testes and ovaries.

Gametogenesis involves the following steps:

1. Multiplemitotic divisionsandcell growthof reproductive cells. This

explains why there are numerous sperm cellsproduced.
2. Two meiotic divisions (Meiosis I and II) occurs to produce haploidcells.
3. Haploiddaughtercellsundergodevelopmentforthemtobecomefunctional
maturegametes.

Spermatogenesis

Figure 2 shows the parts of the spermatozoa,

namely:

1. Nucleus(pluralformnuclei)isfoundinthe
head.
2. Mitochondrion (plural form mitochondria) is
at the middle piece that connects the head
to its tail. It provides energy for the
locomotion.

6 CO_Q4_Science 8_ Module 3
 Illustrated by: Rosa Mia L. Pontillo

Figure 2. Sperm Cell

Illustrated by: Rosa Mia L. Pontillo

7 CO_Q4_Science 8_ Module 3
3. Acrosome is a cap-like structure which develops on the head. It contains
digestive enzymes. These enzymes penetrate the outer sheath of the ovum,
resulting to the merging of the sperm and theovum haploid nucleus.

Oogenesis

This process refers to the creation of gametes called ova which

happens inside the ovaries among female organisms. It begins during
the developmental stages of fetus inside a mother’s womb, when the
reproductive cells of females are formed by meiosis. Figure 3 shows
the phases of the formation of an ovum or egg cell.
 The reproductive female cells known as
oogonium (plural oogonia) undergoes
mitosis and cell growth until it is ready
to undergo meiosis and
becomesprimary oocyte. This primary
oocyte is diploid (2N).
 The primary oocyte begins Meiosis I but
stops its development in prophase I until
puberty, when a girl begins her
menstrualcycle.
 Each month, a hormone known as
Follicle-stimulating hormone (FHS) will
trigger the continued division of the
primary oocyte. The pituitary gland is
responsible for the production of FHS.
The functions of both the ovaries and
the testes are controlled by thishormone. Figure 3. Formation of Egg Cell
 The primary oocyte divides duringthe Illustrated by: Rosa Mia L Pontillo
first meiotic division and two cells of unequal size are formed. One of the
cells receives the complete parts of the cytoplasm and forms a secondary
oocyte, the other cell of smaller size, becomes a polar body. Both cells
contain only one of the pairs of the complete set of chromosomes.
 The haploid secondary oocyte is released by the rupture of the follicles of the
ovary during ovulation and move into the fallopian tube and divides again
during the second meiotic division, but its development is arrested in
metaphaseII.Afterfertilizationisinitiated,thesecondaryoocytecompletesits
second meiotic division, resulting in the formation of a mature ovum and
another polar body. At this point, the ovum is ready to fuse with the
spermatozoan. The polar body may or may not divide, and eventually
degenerate at the end of Meiosis II. The polar bodies shed the excess haploid
sets ofchromosomes.
 If fertilization occurs, the ovum is stimulated to complete meiosis II. It
contains a lot of stored food which is used by the growing embryo at the start
of itsdevelopment.

8 CO_Q4_Science 8_ Module 3
What would happen if meiosis suddenly stops?
The process of meiosis is needed in the formation of gametes, sexual
reproduction, and for the increase of genetic diversity. If there is no meiosis,
reproduction among sexually producing creatures will never occur. Production of
offspringwouldstopandeventually,nomorefuturegenerations.Theearthwillsuffer
extinction of most species among multicellular eukaryotes.

What would happen when something goes wrong during meiosis?

Meiosis may not always proceed normally. Problems during meiosis
sometimeshappenandcausegreatharmduringembryonicdevelopment.Accidents
likemiscarriages,geneticerrors,andbirthdefectsmayoccur.Theseaccidentsmay
affectthemovementofthechromosomesandthefunctioningofthespindlefibers.
Inhumans,non-disjunctionofthechromosomesinMeiosis1orMeiosis2havebeen
known to cause abnormal conditions suchas:
Down syndrome is also identified as Trisomy 21. This condition happens in
chromosome pair 21. During Meiosis I, chromosome pair 21 did not detach from
each other at Anaphase I. One of the gametes produced acquires both members of
the pair of chromosomes. The offspring has 47 chromosomes in his or her cells
instead of the standard 46 chromosomes. Problems with the way the body and the
brain develop are the effects brought by this excess chromosome. Common
physical characteristics of people with Down syndrome include:
1. shortneck
2. smallears
3. smallmouth
4. smallstature
5. flattenednose
6. low muscletone
7. upward slantingeyes
8. short hands and shortfingers
9. Brushfieldspots-orwhitespotsonthecoloredpartoftheeye.

Cri-du-chatSyndrome
Cri-du-chat, the French for cat’s cry, is the sound of a baby having this
condition when he/she cries. This is a genetic condition which is also known as 5p-
(5p minus) syndrome and cat cry syndrome. This is caused by deletion, an
uncommon genetic condition whereby a part of the genetic segment in the small
arm known as the p arm of chromosome 5 is missing. Persons with cri-du-chat
syndrome suffers different symptoms. The variation of symptoms depends on the
size of the deleted part of the p arm. Common physical characteristics of people
with Cri-du- chat syndromeinclude:
1. small headsize
2. widely-spacedeyes
3. round or moon-likeface
4. high-pitched cat-likecry
5. low weight at birthand
6. weak muscle tone duringinfancy

9 CO_Q4_Science 8_ Module 3
Patau Syndrome
Patau syndrome is also identified as Trisomy 13 syndrome. This is a
condition in which each cell of the body of the affected individual has three copies
of chromosome 13 instead of two which is the standard number. This results to an
excess of genetic material which bring disruptions to the normal development of
the individual.
Persons having this chromosomal condition suffer serious physical
abnormalities and intellectual disability whichinclude:
1. cleftlip
2. cleftpalate
3. heartdefects
4. weak muscletone
5. brainabnormalities
6. extra fingers ortoes
7. eyes are poorlydeveloped
Klinefelter Syndrome
Klinefelter Syndrome is also identified as 47, XXY syndrome. This condition
is a sex chromosome disorder due to the occurrence of an extra X chromosomes in
the cell among male individuals. Normally, each human cell has 46 chromosomes.
Twenty-two pairs or 44 chromosomes are called body chromosomes while only one
pair or two of these are called sex chromosomes. Humans have two sex
chromosomes, the X and the Y. Males possess one X sex chromosome and one Y
sex chromosome (XY), and females have two X sex chromosomes (XX). Males with
KlinefeltersyndromeholdanextraXchromosomes(XXY)or47chromosomesintheir
cells. This results to multiple genes in the X chromosomes. These extra genetic
materials interrupt many developmental activities including sexual development.
Common physical characteristics of people with Klinefelter syndromeinclude:
1. smalltestes
2. breastenlargement
3. decreased bonedensity
4. decreasedmusclemass
5. unusually small penis ormicropenis
6. presenceoffewhaironthebodyandface

The affected individual produces a decreased amount of testosterone

hormone, a hormone that controls the male sexual development even before birth
and during puberty. The affected males are infertile.

Why is meiosis important?

Meiosis is important in the formation of sex cells. It makes sure that all
organisms produced sexually contain the standard number of chromosomes.
Among
humanbeingsandmostothermammals,meiosisproducesgeneticvariationthrough
recombination whereby different species exchange genetic materials. This process
produces offspring with mixed traits that vary from either parent. When two germ
cells combine during fertilization, the chances for genetic variation to occur increase
even further. Due to this random recombination of DNA in sexual reproduction,

10 CO_Q4_Science 8_ Module 3
diversity of life on Earthincreases.

11 CO_Q4_Science 8_ Module 3
 What’s More

Activity 2. Math Time!

Directions: Use the diagram on gametogenesis to answer the given questions.
Write your answers on a separate sheet of paper.

Illustrated by: Marilou C. Salazar

1. Suppose there are ten primary oocytes that underwent meiosis, compute the
following:

a. Number of secondaryoocytes
b. Number of matureova
c. Number of polarbodies

2. Supposetherearesixprimaryspermatocytes,computeforthefollowing:

a. Number of secondaryspermatocytes
b. Number ofspermatids
c. Number of spermcells

12 CO_Q4_Science 8_ Module 3
Activity 3. Cool Chromosomes!
Directions: Write the correct number of chromosomes in each cell during spermato-
genesis and oogenesis. Write your answers on a separate sheet of paper.

A.) Felis catus or cat has a chromosome number of 38 (2N).

Illustrated by: Marilou C. Salazar

B.) Ananas comosus or pineapple has a chromosome number of 50 (2N).

Illustrated by: Marilou C. Salazar

Activity 4. All about Down Syndrome!

Directions:Answer the questions below. Write your answers on a separate sheet of
paper.

1. Which chromosome carries Downsyndrome?

2. What are the physical characteristics possessed by a person with Down Syn-
drome? Give at leasttwo.

3. What happens to chromosome 21 in Meiosis I which results to Down

Syndromecondition?
Scoring Rubric for Question no. 3
3: Discussions do not have misconceptions and cite complete scientific evidence.
2: Discussions do not have misconceptions and cite incomplete scientific
evidence. 1:Discussionshavemisconceptionsandciteincompletescientificevidence.
0: No discussions.

13 CO_Q4_Science 8_ Module 3
Activity 5. What’s Cri-du-chat Syndrome?
Directions:Answer the questions below. Write your answers on a separate sheet of
paper.

1. WhenapersonhasCri-du-ChatSyndrome,whatchromosomeisaltered?

2. What are the physical characteristics possessed by a person with Cri-du-

Chat Syndrome. Give at leasttwo.

3. What are the other names for Cri-du-ChatSyndrome?

What I Have Learned

Activity 6. Matching Type

Directions:MatchColumnAwithitscorrespondingdescriptioninColumnB.
Writetheletterofyouranswersonaseparatesheetofpaper.

ColumnA Column B

1. Gametes A. testes andovary

2. Gametogenesis B. exchange of genetic materialbetween
3. Geneticrecombination differentorganisms
4. Gonad C. common physical characteristics ofpeople
5. Haploid with Patausyndrome
6. Importanceofmeiosis D. ensures that all organisms produced via
sexual reproduction contain the correct
number of chromosomes by producing
haploid gametes.
7. Oogonium E. an illness in the sex chromosomeamong
8. Ovulation males which is also identifiedas
9. With extra fingers KlinefelterSyndrome
10. 47,XXYsyndrome F. the release of eggs from theovary
G. having a complete set of each pair
of chromosome
H. The immature female reproductivecells
I. sexcells
J. single set of unpairedchromosomes
K. process by which gametes, or sex cells,
are produced by anorganism

14 CO_Q4_Science 8_ Module 3
 What I Can Do

Activity 7. Amazing Meiosis!

Directions: A. Write the correct chromosome number of the selected organisms.
Write your answers on a separate sheet of paper.

Organism Diploid Number Haploid Number

1. Chicken 39

2. Corn 20

3. Durian 56

4. Frog 13

5. Guava 22

6. Melon 24

7. Mosquito 3

8. Rat 21

9. Starfish 36

10. Sunflower 17

Directions: B. Explain the significance of meiosis in maintaining the chromosome

number of an organism. (3 points)

3: Discussions do not have misconceptions and cite complete scientific evidence.

2: Discussions do not have misconceptions and cite incomplete scientific
evidence. 1:Discussionshavemisconceptionsandciteincompletescientificevidence.
0: No discussions.

15 CO_Q4_Science 8_ Module 3
 Assessment

Directions:Choose the letter of the correct answer. Write your answers on a separate
sheet ofpaper.

1. Whichisthecorrectseriesofcellularstagesinspermatogenesis?
A. spermatids – spermatocytes -spermatozoa
B. spermatids – spermatozoa -spermatocytes
C. spermatocytes – spermatozoa -spermatids
D. spermatocytes – spermatids -spermatozoa
2. Which process does thecreation of polar bodies happen?
A. cytokinesis
B. mitosis
C. oogenesis
D. spermatogenesis
3. Which of the following is involved in the maturation ofsperms?
A. growth of primary spermatocytes throughmitosis
B. formationofovumfromprimaryoocytesthroughmeiosis
C. creation of polar bodies from primary oocytes throughmeiosis
D. developmentofspermatidsfromprimaryspermatocytesthroughmeiosisII
4. How many spermatozoa are produced after a primary spermatocyte
undergo spermatogenesis?
A. 2
B. 4
C. 6
D. 8
5. Which statement is TRUE aboutoogenesis?
A. Polar bodiesdegenerate.
B. Ovum produced isdiploid.
C. Primary oocyte ishaploid.
D. Secondary oocyte isdiploid.
6. Which statement is FALSE aboutspermatogenesis?
A. The secondary spermatocytes arehaploid.
B. Ittakesplaceinthetestesofmaleanimals.
C. Each primary spermatocyte becomes four diploid spermatids.
D. Each primary spermatocyte becomes four haploidspermatids.
7. Which is produced by each primary oocyteafter oogenesis?
A. fourova
B. oneovum
C. one polar body and threeova
D. three polar bodies and oneovum

16 CO_Q4_Science 8_ Module 3
8. Which of the following are formed aftergametogenesis?
A. bodycells
B. gonads
C. sexcells
D. somaticcells

9. Whatistheroleofthepolarbodiesduringoogenesis?
A. It increases the number ofsperms.
B. It increases the number of egg cells.
C. It weakens the ovum duringfertilization.
D. It removes the excess haploid sets ofchromosomes.

10. Which statement is FALSE aboutacrosome?

A. It is a cap-likestructure.
B. It contains digestiveenzymes.
C. It develops on the head of theovum.
D. Itsenzymesbreaktheoutersheathoftheovum.

11. The following are the common physical characteristics of people with
Klinefelter syndromeEXCEPT:
A. smalltestes
B. breastenlargement
C. increased musclemass
D. presenceoffewhaironthebodyandface

12. WhatisthenumberofthealteredchromosomeinPatausyndrome?
A. 5
B. 13
C. 18
D. 21

13. Which is correct about spermatogenesis andoogenesis?

A. spermatogenesis:1sperm;oogenesis:2eggs
B. spermatogenesis:2sperms;oogenesis:1egg
C. spermatogenesis:4sperms;oogenesis:1egg
D. spermatogenesis: 8 sperms; oogenesis: 4eggs

14. Which one indicates a normal humanmale?

A. Xchromosome
B. XXchromosomes
C. XY chromosomes
D. XXYchromosomes

15. The following are the significance of meiosisEXCEPT:

A. geneticvariability
B. sex cellformation
C. asexualreproduction
D. normal chromosomal numberupkeep

17 CO_Q4_Science 8_ Module 3
 Additional Activities

Activity 8. Healthy Tips!

Directions:Putacheckmark()ifthestatementisapreventivehealthcarepractice
against fetal abnormalities and an X mark if not. Write your answers on
a separate sheet ofpaper.

1. Managestress.
2. Exerciseregularly.
3. Avoid prenatalcare.
4. Keep a normalweight.
5. Self-medicate whensick.
6. Eat plenty of sweetfoods.
7. Drink alcoholic and caffeinatedbeverages.
8. Expose self to radiation and x-raysoften.
9. Avoid smoking and stay away from second-handsmoke.
10. Keep track of medical history, medications, and immunizations before
pregnancy.

18 CO_Q4_Science 8_ Module 3
CO_Q4_Science 8_ Module 3 19
Additional Assessment Additional Activities
Activity
1. D 11. C Activity 7: Amazing Meios is!
Activity 8: 2. C 12. B A.)
Identification 1. 78 4. 26 7. 6 10. 34
3. D 13. C
2. 10 5. 11 8. 42
4. B 14. C
1. √ 6. X 3. 28 6. 12 9. 18
5. A 15. C
2. √ 7. X
6. C
3. X 8. X B.) The primary function of meios is is the reduction of
7. D
4. √ 9. √ the number of chromosomes of the gametes from diploid
8. C
5. X 10. √ (2N) to haploid (N) so that the normal chromosome
9. D
numbe r of the organis m may be maintained after the
10. C
union of sex cells during fertilization.
What I Have Learn ed What’s More
Activity 6: Matching Type Activity 5: Cri-du-chat Syndrome
1. I 6. D 1. Chromosome 5
2. K 7. H 2.) 1. Small head size 5. Widely spaced eyes
3. B 8. F 2. Round or moon-like face 6. Low birth weight
4. A 9. C 3. High-pitched cat-like cry
5. J 10. E 4. Weak muscle tone during infancy
3.) 1. Cat’s cry syndrome 2. 5p- or 5p minus
What’s More What’s More
Activity 4: Down Syndrome
Activity 3: Cool Chromosome s!
1. Chromosome 21
2.) 1. Low muscle tone 7. Small stature A.) 1. 38 B.) 1. 50
2. Flattened nose 8. Small mouth 2. 19 2. 25
3. Short neck 9. Slanting eyes 3. 19 3. 25
4. Small ears 4. 19 4. 25
5. Wide, short hands with short fingers 5. 19 5. 25
6. White spots on the colored part of the 6. 19 6. 25
eye known as Brush field spots 7. 19 7. 25
3. Chromosome pair 21 fails to separate from
each other during Meiosis I.
What’s More What’s New
What' s In What I Know
Activity 2: Math Activity 1 – True or False (Pretest)
Time! What’s the
Numb er? 1. True 6. True 1. A 9. C
A.) a. 10
2. True 7. True 2. A 10. A
b. 10 3. False 8. False
1. 2N 8. N 3. B 11. C
c. 30 2. 2N 9. N 4. False 9. True
4. B 12. D
3. N 10. N 5. False 10. False
5. B 13. D
B.) a. 12 4. N 11. N
6. B 14. D
b. 24 5. N 12. N
6. N 13. N 7. B 15. D
c. 24
7. N 14. N 8. B
Answer Key
20 CO_Q4_Science 8_ Module 3
References
Books

Campo, Pia C., May R. Chavez, Maria Helen D.H. Catalan, Ph.D., Leticia V. Catris,
Ph.D., Marlene B. Ferido, Ph.D., Ian Kendrich C. Fontanilla, Ph.D., Jacqueline
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21 CO_Q4_Science 8_ Module 3
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